edoc-vmtest

Synthetic Studies on the Sporolides : Exploration of the Enediyne Route

Bonazzi, S. and Binaghi, M. and Fellay, C. and Wach, J. Y. and Gademann, K.. (2010) Synthetic Studies on the Sporolides : Exploration of the Enediyne Route. Synthesis, 4. pp. 631-642.

[img] PDF - Published Version
Restricted to Repository staff only

214Kb

Official URL: http://edoc.unibas.ch/dok/A5841601

Downloads: Statistics Overview

Abstract

Synthetic studies towards the construction of the cyclopenta[a]indene fragment of the heptacyclic marine metabolite sporolide are reported based on a hypothetical biosynthesis. The key step of this biogenetic proposal includes a Bergman cyclization of an enediyne precursor. The enediyne target of this synthetic study was prepared by Sonogashira cross-coupling of two fragments, of which the cyclopentane fragment was prepared from cyclopentenone, Morita-Baylis-Hillman reaction, and enantioselective Sharpless dihydroxylation.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Former Organization Units Chemistry > Organische Chemie (Gademann)
UniBasel Contributors:Gademann, Karl
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Georg Thieme
ISSN:0039-7881
e-ISSN:1437-210X
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
edoc DOI:
Last Modified:02 Feb 2017 10:51
Deposited On:14 Sep 2012 06:56

Repository Staff Only: item control page