Cerdan, S. and Lotscher, H. R. and Kunnecke, B. and Seelig, J.. (1989) Monoclonal antibody-coated magnetite particles as contrast agents in magnetic resonance imaging of tumors. Magnetic Resonance in Medicine, 12 (2). pp. 151-163.
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Official URL: http://edoc.unibas.ch/dok/A5257479
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Abstract
A highly specific and powerful magnetic resonance imaging contrast agent has been prepared by coating magnetite (Fe3O4) particles with monoclonal antibodies directed against a tumor antigen. The preparation maintains both the immunoreactivity of the monoclonal antibody and the full relaxing capability of the magnetite particle. MRI image contrast by spin-echo methods can be easily induced in a concentration range of 1-10 nM of the antibody-coated magnetite particles.
Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Biophysical Chemistry (Seelig J) |
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UniBasel Contributors: | Seelig, Joachim |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
Publisher: | Wiley-Liss |
ISSN: | 0740-3194 |
e-ISSN: | 1522-2594 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Identification Number: | |
Last Modified: | 14 Nov 2017 13:39 |
Deposited On: | 22 Mar 2012 13:18 |
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