Spano, D. and Cimmino, F. and Capasso, M. and D'Angelo, F. and Zambrano, N. and Terracciano, L. and Iolascon, A.. (2008) Changes of the hepatic proteome in hepatitis B-infected mouse model at early stages of fibrosis. Journal of Proteome Research, Vol. 7, H. 7. pp. 2642-2653.
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Official URL: http://edoc.unibas.ch/dok/A6006641
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Abstract
Liver fibrosis (LF) is the accumulation of extracellular matrix (ECM) proteins due to chronic liver injury. We used two-dimensional differential in-gel electrophoresis (2D-DIGE) to perform a comparative analysis of cytosolic and nuclear protein patterns of nontransgenic (NTg) and HBV transgenic (Tg) mice livers at early stages of fibrosis. We identified several candidate proteins, involved in a variety of pathways, which could be used as putative biomarkers for LF early detection.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB > Molekulare Pathologie (Terracciano) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB > Molekulare Pathologie (Terracciano) |
|---|---|
| UniBasel Contributors: | Terracciano, Luigi M. |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | American Chemical Society |
| ISSN: | 1535-3893 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Related URLs: | |
| Identification Number: |
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| Last Modified: | 08 Nov 2012 16:23 |
| Deposited On: | 08 Nov 2012 16:18 |
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