Dumortier, Alexis and Durham, André-Dante and Di Piazza, Matteo and Vauclair, Sophie and Koch, Ute and Ferrand, Gisèle and Ferrero, Isabel and Demehri, Shadmehr and Song, Lynda Li and Farr, Andrew G. and Leonard, Warren J. and Kopan, Raphael and Miele, Lucio and Hohl, Daniel and Finke, Daniela and Radtke, Freddy. (2010) Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin. PLoS one, Vol. 5, H. 2 , e9258.
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Official URL: http://edoc.unibas.ch/dok/A6003937
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Abstract
The Notch pathway is essential for proper epidermal differentiation during embryonic skin development. Moreover, skin specific loss of Notch signaling in the embryo results in skin barrier defects accompanied by a B-lymphoproliferative disease. However, much less is known about the consequences of loss of Notch signaling after birth.
| Faculties and Departments: | 03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Children's Hospital > Developmental Immunology (Finke) |
|---|---|
| UniBasel Contributors: | Finke, Daniela |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | PubMed Central |
| ISSN: | 1932-6203 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Related URLs: | |
| Identification Number: |
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| Last Modified: | 07 Dec 2012 13:04 |
| Deposited On: | 07 Dec 2012 13:03 |
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