Tyndall, A.. (2009) Cellular therapy of systemic lupus erythematosus. Lupus, 18 (5). pp. 387-393.
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Official URL: http://edoc.unibas.ch/dok/A6003930
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Abstract
Immunoablation with autologous hematopoietic stem cell rescue has been used in over 1,300 autoimmune disease patients, around 150 with SLE. Some patients have experienced durable remissions with loss of autoantibodies, whereas others either did not respond or died as a result of the treatment. Prospective randomised trials are required and are being planned to establish the place for this potentailly curative strategy. Mesenchymal stem cells are in an exploratory phase for the treatment of acute autoimmune disease including SLE. The principle is that they home to inflammed tissue and exert an antiinflammatory paracrine effect.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Ehemalige Einheiten Medizinische Fächer (Klinik) > Rheumatologie FPS (Tyndall) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Ehemalige Einheiten Medizinische Fächer (Klinik) > Rheumatologie FPS (Tyndall) 03 Faculty of Medicine > Departement Biomedizin > Former Units at DBM > Rheumatologie FPS (Tyndall) |
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| UniBasel Contributors: | De Vere-Tyndall, Alan |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | SAGE |
| ISSN: | 0961-2033 |
| e-ISSN: | 1477-0962 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Related URLs: | |
| Identification Number: |
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| Last Modified: | 02 Nov 2017 09:26 |
| Deposited On: | 01 Mar 2013 11:13 |
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