von Wyl, Viktor and Ehteshami, Maryam and Symons, Jori and Bürgisser, Philippe and Nijhuis, Monique and Demeter, Lisa M. and Yerly, Sabine and Böni, Jürg and Klimkait, Thomas and Schuurman, Rob and Ledergerber, Bruno and Götte, Matthias and Günthard Huldrych, F. and Swiss HIV Cohort Study, . (2010) Epidemiological and biological evidence for a compensatory effect of connection domain mutation N348I on M184V in HIV-1 reverse transcriptase. The Journal of Infectious Diseases, Vol. 201, no. 7. pp. 1054-1062.
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Abstract
The connection domain mutation N348I confers resistance to zidovudine (AZT) and is associated with the lamivudine (3TC) mutation M184V. We explored the biochemical and virological influence of N348I in the context of M184V.
| Faculties and Departments: | 03 Faculty of Medicine > Departement Biomedizin > Division of Medical Microbiology > Transplantation Virology (Hirsch) 03 Faculty of Medicine > Departement Biomedizin > Division of Medical Microbiology > Molecular Virology (Klimkait) |
|---|---|
| UniBasel Contributors: | Klimkait, Thomas and Hirsch, Hans H. |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | The University of Chicago Press |
| ISSN: | 0022-1899 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Language: | English |
| Related URLs: | |
| Identification Number: |
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| edoc DOI: | |
| Last Modified: | 13 Mar 2018 17:19 |
| Deposited On: | 26 Apr 2013 06:55 |
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