Schneider, A. and Falkai, P. and Papassotiropoulos, A.. (2010) Molekulare Grundlagen Tau-Protein-vermittelter Toxizität : neue experimentelle Therapiestrategien zur Behandlung der Alzheimer-Erkrankung. Der Nervenarzt, Vol. 81, H. 11. pp. 1289-1297.
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Official URL: http://edoc.unibas.ch/dok/A6005197
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Abstract
Neurofibrillary tangles are the hallmark of Alzheimer's disease together with amyloid plaques. They are composed of hyperphosphorylated and aggregated Tau proteins. Consequently, experimental disease modifying approaches include kinase and aggregation inhibitors as well as substances which increase degradation of Tau proteins.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Molekulare Neurowissenschaften (Papassotiropoulos) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Molekulare Neurowissenschaften (Papassotiropoulos) |
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| Item Type: | Article, refereed |
| Publisher: | Springer-Verlag |
| ISSN: | 0028-2804 |
| Note: | Note: Englischer Titel: Molecular principles of tau-induced toxicity: new experimental therapy strategies for treatment of Alzheimer's disease -- Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
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| Last Modified: | 24 May 2013 09:23 |
| Deposited On: | 24 May 2013 09:13 |
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