Garcia de la Fuente, Isabel and Ansari, Marc and Rougemont, Anne-Laure and Passweg, Jakob R. and Gumy-Pause, Fabienne and Ozsahin, Hulya and Lobrinus, Johannes A. and Posfay-Barbe, Klara M.. (2010) Acute disseminated fatal toxoplasmosis after haploidentical stem cell transplantation despite atovaquone prophylaxis in a young man. Pediatric infectious disease journal, Vol. 29, no. 11. pp. 1059-1060.
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Official URL: http://edoc.unibas.ch/dok/A6005931
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Abstract
We describe a case of fatal acute disseminated breakthrough toxoplasmosis in a 19-year-old adolescent after haploidentical hematopoietic stem cell transplantation for acute lymphoblastic leukemia despite continued atovaquone prophylaxis. Diagnosis was at necropsy, and confirmed by postmortem polymerase chain reaction analysis in plasma. This report illustrates the need for protozoal monitoring despite atovaquone prophylaxis, in severely immunocompromised patients with intolerance to standard treatment.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Hämatologie > Hämatologie (Passweg) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Hämatologie > Hämatologie (Passweg) |
|---|---|
| UniBasel Contributors: | Passweg, Jakob R. |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Lippincott Williams & Wilkins |
| ISSN: | 0891-3668 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: | |
| Last Modified: | 24 May 2013 09:23 |
| Deposited On: | 24 May 2013 09:13 |
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