Osthoff, Michael and Rovó, Alicia and Stern, Martin and Danner, Doris and Gratwohl, Alois and Tichelli, André and Trendelenburg, Marten. (2010) Mannose-binding lectin levels and major infections in a cohort of very long-term survivors after allogeneic stem cell transplantation. Haematologica, Vol. 95, H. 8. pp. 1389-1396.
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Official URL: http://edoc.unibas.ch/dok/A6003544
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Abstract
Life-threatening infections are a major cause of death after allogeneic stem cell transplantation. Complement Mannose-binding lectin is a key component of innate immunity. Functional deficiency of mannose-binding lectin due to genetic polymorphism is frequent. Previous reports showed conflicting results with respect to the influence of functional mannose-binding lectin deficiency on infectious risk after allogeneic stem cell transplantation. The aim of this study was to clarify the impact of low mannose-binding lectin levels on infectious risk in a unique cohort of very long-term survivors after stem cell transplantation.
| Faculties and Departments: | 03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Clinical Immunology (Trendelenburg) 03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Ehemalige Einheiten Querschnittsfächer (Klinik) > Diagnostische Hämatologie (Tichelli) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Ehemalige Einheiten Querschnittsfächer (Klinik) > Diagnostische Hämatologie (Tichelli) 03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Ehemalige Einheiten Medizinische Fächer (Klinik) > Hämatologie (Gratwohl) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Ehemalige Einheiten Medizinische Fächer (Klinik) > Hämatologie (Gratwohl) 03 Faculty of Medicine > Departement Biomedizin > Former Units at DBM > Immunotherapy (Stern) |
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| UniBasel Contributors: | Tichelli, André and Gratwohl, Alois A. and Trendelenburg, Marten and Stern, Martin Andreas and Rovó, Alicia |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| ISSN: | 0017-6567 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
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| Last Modified: | 21 Jun 2013 12:29 |
| Deposited On: | 21 Jun 2013 12:24 |
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