Nollmann, Friederike I. and Dowling, Andrea and Kaiser, Marcel and Deckmann, Klaus and Grösch, Sabine and Ffrench-Constant, Richard and Bode, Helge B.. (2012) Synthesis of szentiamide, a depsipeptide from entomopathogenic Xenorhabdus szentirmaii with activity against Plasmodium falciparum. Beilstein journal of organic chemistry, Vol. 8. pp. 528-533.
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Abstract
The synthesis of the recently characterized depsipeptide szentiamide (1), which is produced by the entomopathogenic bacterium Xenorhabdus szentirmaii, is described. Whereas no biological activity was previously identified for 1, the material derived from the efficient synthesis enabled additional bioactivity tests leading to the identification of a notable activity against insect cells and Plasmodium falciparum, the causative agent of malaria
| Faculties and Departments: | 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Medical Parasitology and Infection Biology (MPI) > Parasite Chemotherapy (Mäser) |
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| UniBasel Contributors: | Kaiser, Marcel |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Beilstein-Institut zur Förderung der Chemischen Wissenschaften |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Language: | English |
| Related URLs: | |
| Identification Number: |
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| edoc DOI: | |
| Last Modified: | 31 Dec 2015 10:53 |
| Deposited On: | 19 Jul 2013 07:40 |
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