Kouyos, R. D. and von Wyl, V. and Yerly, S. and Boni, J. and Rieder, P. and Joos, B. and Taffe, P. and Shah, C. and Burgisser, P. and Klimkait, T. and Weber, R. and Hirschel, B. and Cavassini, M. and Rauch, A. and Battegay, M. and Vernazza, P. L. and Bernasconi, E. and Ledergerber, B. and Bonhoeffer, S. and Gunthard, H. F. and Swiss HIV Cohort Study, . (2011) Ambiguous nucleotide calls from population-based sequencing of HIV-1 are a marker for viral diversity and the age of infection. Clinical Infectious Diseases, Vol. 52, H. 4. pp. 532-539.
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Abstract
The time passed since the infection of a human immunodeficiency virus (HIV)-infected individual (the age of infection) is an important but often only poorly known quantity. We assessed whether the fraction of ambiguous nucleotides obtained from bulk sequencing as done for genotypic resistance testing can serve as a proxy of this parameter.
| Faculties and Departments: | 03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Infection Biology (Khanna) 03 Faculty of Medicine > Departement Biomedizin > Division of Medical Microbiology > Molecular Virology (Klimkait) |
|---|---|
| UniBasel Contributors: | Klimkait, Thomas and Battegay, Manuel E. |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Oxford University Press |
| ISSN: | 1058-4838 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Language: | English |
| Related URLs: | |
| Identification Number: |
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| edoc DOI: | |
| Last Modified: | 09 Apr 2018 06:26 |
| Deposited On: | 16 Aug 2013 07:33 |
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