Xin, Xiaorong and Fan, Bin and Flammer, Josef and Miller, Neil R. and Jaggi, Gregor P. and Killer, Hanspeter E. and Meyer, Peter and Neutzner, Albert. (2011) Meningothelial cells react to elevated pressure and oxidative stress. PLoS one, Vol. 6, H. 5 , e20142.
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Official URL: http://edoc.unibas.ch/dok/A6004774
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Abstract
Meningothelial cells (MECs) are the cellular components of the meninges enveloping the brain. Although MECs are not fully understood, several functions of these cells have been described. The presence of desmosomes and tight junctions between MECs hints towards a barrier function protecting the brain. In addition, MECs perform endocytosis and, by the secretion of cytokines, are involved in immunological processes in the brain. However, little is known about the influence of pathological conditions on MEC function; e.g., during diseases associated with elevated intracranial pressure, hypoxia or increased oxidative stress.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Spezialfächer (Klinik) > Ehemalige Einheiten Spezialfächer (Klinik) > Ophthalmologie (Flammer) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Spezialfächer (Klinik) > Ehemalige Einheiten Spezialfächer (Klinik) > Ophthalmologie (Flammer) 03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Ocular Pharmacology and Physiology (Neutzner/Meyer) |
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| UniBasel Contributors: | Flammer, Josef and Meyer, Peter and Neutzner, Albert |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Public Library of Science |
| ISSN: | 1932-6203 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Related URLs: | |
| Identification Number: |
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| Last Modified: | 08 May 2015 08:45 |
| Deposited On: | 25 Oct 2013 08:32 |
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