Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) : a consensus conference proposal for a standardized approach

Halter, J. and Schüpbach, W. M. M. and Casali, C. and Elhasid, R. and Fay, K. and Hammans, S. and Illa, I. and Kappeler, L. and Krähenbühl, S. and Lehmann, T. and Mandel, H. and Marti, R. and Mattle, H. and Orchard, K. and Savage, D. and Sue, C. M. and Valcarcel, D. and Gratwohl, A. and Hirano, M.. (2011) Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) : a consensus conference proposal for a standardized approach. Bone marrow transplantation, Vol. 46, H. 3. pp. 330-337.

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Official URL: http://edoc.unibas.ch/dok/A6006584

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Abstract

Allogeneic hematopoietic SCT (HSCT) has been proposed as a treatment for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). HSCT has been performed in nine patients using different protocols with varying success. Based on this preliminary experience, participants of the first consensus conference propose a common approach to allogeneic HSCT in MNGIE. Standardization of the transplant protocol and the clinical and biochemical assessments will allow evaluation of the safety and efficacy of HSCT as well as optimization of therapy for patients with MNGIE.

Faculties and Departments:	03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Klinische Pharmakologie > Klinische Pharmakologie (Krähenbühl) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Klinische Pharmakologie > Klinische Pharmakologie (Krähenbühl)
UniBasel Contributors:	Krähenbühl, Stephan
Item Type:	Article, refereed
Article Subtype:	Research Article
Publisher:	Nature Publishing Group
ISSN:	0268-3369
Note:	Publication type according to Uni Basel Research Database: Journal article
Last Modified:	25 Oct 2013 08:33
Deposited On:	25 Oct 2013 08:33

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