Tsang, A. S. and Ingram, K. and Keiser, J. and Hibbert, D. B. and Todd, M. H.. (2013) Enhancing the usefulness of cross dehydrogenative coupling reactions with a removable protecting group. Organic & biomolecular chemistry : an international journal of synthetic, physical and biomolecular organic chemistry, Vol. 11, H. 30. pp. 4921-4924.
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Official URL: http://edoc.unibas.ch/dok/A6223297
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Abstract
A removable protecting group has been identified that allows the products of widely-used cross dehydrogenative couplings to be synthetically elaborated. The method can be used with enantiopure amines with no loss of enantiomeric excess. The methodology is exemplified by a new synthesis of enantiopure praziquantel, the drug used in the treatment of millions of people suffering from the neglected tropical disease, schistosomiasis
Faculties and Departments: | 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Medical Parasitology and Infection Biology (MPI) > Helminth Drug Development (Keiser) |
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UniBasel Contributors: | Keiser, Jennifer |
Item Type: | Article, refereed |
Article Subtype: | Book Review |
Publisher: | Royal Society of Chemistry |
ISSN: | 1477-0520 |
Note: | Publication type according to Uni Basel Research Database: Journal item |
Related URLs: | |
Identification Number: |
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Last Modified: | 27 Mar 2014 13:12 |
Deposited On: | 27 Mar 2014 13:12 |
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