Li-Wan-Po, Alain and Girard, Thierry and Farndon, Peter and Cooley, Candy and Lithgow, James. (2010) Pharmacogenetics of CYP2C19: functional and clinical implications of a new variant CYP2C19*17. British journal of clinical pharmacology, Vol. 69, H. 3. pp. 222-230.
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Official URL: http://edoc.unibas.ch/dok/A6007646
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Abstract
Cytochrome P450 2C19 metabolizes many important drugs. In 2006, a variant allele (CYP2C19*17) associated with increased activity was discovered, but its likely clinical significance is controversial. Investigators disagree about the phenotype to be assigned to the two CYP2C19*17 genotypes. The aim of this study was to provide a critical summary, helpful to prescribers.
| Faculties and Departments: | 03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Perioperative Patient Safety (Girard/Treves) |
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| UniBasel Contributors: | Girard, Thierry |
| Item Type: | Article, refereed |
| Article Subtype: | Further Journal Contribution |
| Publisher: | Blackwell |
| ISSN: | 0306-5251 |
| Note: | Publication type according to Uni Basel Research Database: Journal item |
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| Last Modified: | 20 Jun 2014 07:55 |
| Deposited On: | 20 Jun 2014 07:55 |
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