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Plasmodium falciparum and Plasmodium vivax genotypes and efficacy of intermittent preventive treatment in Papua New Guinea

Barnadas, Celine and Senn, Nicolas and Iga, Jonah and Timinao, Lincoln and Javati, Sarah and Malau, Elisheba and Rarau, Patricia and Reeder, John C. and Siba, Peter and Karunajeewa, Harin and Zimmerman, Peter A. and Davis, Timothy M. and Mueller, Ivo. (2014) Plasmodium falciparum and Plasmodium vivax genotypes and efficacy of intermittent preventive treatment in Papua New Guinea. Antimicrobial agents and chemotherapy, Vol. 58, H. 11. pp. 6958-6961.

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Official URL: http://edoc.unibas.ch/dok/A6319186

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Abstract

Intermittent preventive treatment of infants (IPTi) reduces early childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimalarial drugs in case management, there are few equivalent data relating to their protective efficacy when used as IPTi. The present data from an IPTi trial in Papua New Guinea demonstrate how these markers can predict protective efficacy of IPTi for both Plasmodium falciparum and Plasmodium vivax.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Health Interventions > Malaria Interventions (Lengeler)
UniBasel Contributors:Mueller, Ivo and Senn, Nicolas
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:American Society for Microbiology
ISSN:0066-4804
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:09 Jan 2015 09:24
Deposited On:09 Jan 2015 09:24

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