Zavolan, M. and van Nimwegen, E.. (2006) The types and prevalence of alternative splice forms. Current opinion in structural biology, Vol. 16, H. 3. pp. 362-367.
Full text not available from this repository.
Official URL: http://edoc.unibas.ch/dok/A5259663
Downloads: Statistics Overview
Abstract
The finding that eukaryotic gene structures are extremely complex prompted the development of new experimental techniques for the accurate measurement of transcription start site usage and of the expression of alternative splice forms. On the computational side, analyses of large databases of splice variants revealed differences in the length, motif composition and selection pressure between constitutive and alternatively spliced exons. Such features are being incorporated into novel computational tools for gene structure prediction. The result of these investigations is a continuously improving catalogue of alternative splice forms. How the expression of these alternative splice forms is regulated remains one of the major open questions.
Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Computational & Systems Biology > Bioinformatics (van Nimwegen) 05 Faculty of Science > Departement Biozentrum > Computational & Systems Biology > Bioinformatics (Zavolan) |
---|---|
UniBasel Contributors: | van Nimwegen, Erik and Zavolan, Mihaela |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
Publisher: | Current Biology |
ISSN: | 0959-440X |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Related URLs: | |
Identification Number: |
|
Last Modified: | 14 Sep 2012 06:50 |
Deposited On: | 22 Mar 2012 13:23 |
Repository Staff Only: item control page