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An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes

Patra, Malay and Bauman, Andreas and Mari, Cristina and Fischer, Christiane A. and Blacque, Olivier and Häussinger, Daniel and Gasser, Gilles and Mindt, Thomas L.. (2014) An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes. Chemical Communications, 50 (78). pp. 11523-11525.

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Official URL: http://edoc.unibas.ch/dok/A6348327

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Abstract

(89)Zr-based imaging agents hold great promise as novel radio-tracers in nuclear medicine. However, insufficient stability of currently used radiometal complexes in vivo is a safety concern for clinical applications. We herein report the first octadentate bifunctional chelating agent for the development of (89)Zr-labelled (bio)conjugates with improved stability.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Nuclear Magnetic Resonance (Häussinger)
UniBasel Contributors:Mindt, Thomas L. and Häussinger, Daniel
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Royal Society of Chemistry
ISSN:0022-4936
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:28 Nov 2016 15:09
Deposited On:10 Apr 2015 09:12

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