Manos-Turvey, A. and Watson, E. E. and Sykes, M. L. and Jones, A. J. and Baell, J. B. and Kaiser, M. and Avery, V. M. and Payne, R. J.. (2015) Synthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents. MedChemComm, Vol. 6, H. 3. pp. 403-406.
Full text not available from this repository.
Official URL: http://edoc.unibas.ch/dok/A6373535
Downloads: Statistics Overview
Abstract
The synthesis and anti-trypanosomal activity of a compound library based on a phenoxymethylbenzamide hit discovered in a high throughput screen is described. Several of the analogues exhibited potent activity against Trypanosoma brucei rhodesiense, a human infective strain of the trypanosome parasite, that serve as lead compounds for further optimisation.
| Faculties and Departments: | 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Medical Parasitology and Infection Biology (MPI) > Parasite Chemotherapy (Mäser) |
|---|---|
| UniBasel Contributors: | Kaiser, Marcel |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 2040-2503 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Related URLs: | |
| Identification Number: |
|
| Last Modified: | 05 Jun 2015 08:53 |
| Deposited On: | 05 Jun 2015 08:53 |
Repository Staff Only: item control page