Reimer, Daniela and Nollmann, Friederike I. and Schultz, Katharina and Kaiser, Marcel and Bode, Helge B.. (2014) Xenortide biosynthesis by entomopathogenic xenorhabdus nematophila. Journal of natural products, 77 (8). pp. 1976-1980.
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Official URL: http://edoc.unibas.ch/41960/
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Abstract
The biosynthesis gene cluster of the xenortides and a new derivative, xenortide D, which is produced in only trace amounts, was identified in Xenorhabdus nematophila. The structure of xenortide D was elucidated using a combination of labeling experiments followed by MS analysis and was confirmed by synthesis. Bioactivity tests revealed a weak activity of tryptamine-carrying xenortides against Plasmodium falciparum and Trypanosoma brucei.
| Faculties and Departments: | 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Medical Parasitology and Infection Biology (MPI) > Parasite Chemotherapy (Mäser) |
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| UniBasel Contributors: | Kaiser, Marcel |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | American Society of Pharmacognosy |
| ISSN: | 0163-3864 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
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| Last Modified: | 30 Jun 2016 11:03 |
| Deposited On: | 19 Apr 2016 09:47 |
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