Kornilova, S. V. and Yasem, P. and Grigoriev, D. N. and Kapinos, L. E. and Totova, Y. and Blagoi, Y. P. and Galkin, V. L.. (1998) Kalorimetricheskoe izuchenie perekhoda spiral'-klubok v DNK pri vzaimodeistvii s ionami Cu2+. Biofizika, 43 (1). pp. 37-42.
Full text not available from this repository.
Official URL: http://edoc.unibas.ch/48627/
Downloads: Statistics Overview
Abstract
Using the method of differential scanning calorimetry, the DNA helix-coil transition was studied in solutions (10(-3) M Na+, 10(-3) M tris HCl, pH 7.0) containing divalent copper ions at relative metal ion concentrations (Mt2+/PDNA) ranging from 0.2 to 20. Dependences of the melting temperature and enthalpy on relative ion concentration were determined. An aggregation of Cu(2+) + DNA complexes in the range of average ion concentration was established. It is shown that the melting enthalpy of "units" increases with copper ion concentration. The data obtained were compared with values determined by UV-spectroscopy. Association constants for Cu2+ binding to DNA were defined by the ligand theory.
| Faculties and Departments: | 05 Faculty of Science |
|---|---|
| UniBasel Contributors: | Kapinos Schneider, Larisa E. E |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Izdatel'stvo Nauka |
| ISSN: | 0006-3029 |
| e-ISSN: | 0006-3029 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
|
| Last Modified: | 22 Nov 2017 10:07 |
| Deposited On: | 22 Nov 2017 10:07 |
Repository Staff Only: item control page