Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

Wain, Louise V. and Shrine, Nick and Artigas, María Soler and Erzurumluoglu, A. Mesut and Noyvert, Boris and Bossini-Castillo, Lara and Obeidat, Ma'en and Henry, Amanda P. and Portelli, Michael A. and Hall, Robert J. and Billington, Charlotte K. and Rimington, Tracy L. and Fenech, Anthony G. and John, Catherine and Blake, Tineka and Jackson, Victoria E. and Allen, Richard J. and Prins, Bram P. and Understanding Society Scientific Group, and Campbell, Archie and Porteous, David J. and Jarvelin, Marjo-Riitta and Wielscher, Matthias and James, Alan L. and Hui, Jennie and Wareham, Nicholas J. and Zhao, Jing Hua and Wilson, James F. and Joshi, Peter K. and Stubbe, Beate and Rawal, Rajesh and Schulz, Holger and Imboden, Medea and Probst-Hensch, Nicole M. and Karrasch, Stefan and Gieger, Christian and Deary, Ian J. and Harris, Sarah E. and Marten, Jonathan and Rudan, Igor and Enroth, Stefan and Gyllensten, Ulf and Kerr, Shona M. and Polasek, Ozren and Kähönen, Mika and Surakka, Ida and Vitart, Veronique and Hayward, Caroline and Lehtimäki, Terho and Raitakari, Olli T. and Evans, David M. and Henderson, A. John and Pennell, Craig E. and Wang, Carol A. and Sly, Peter D. and Wan, Emily S. and Busch, Robert and Hobbs, Brian D. and Litonjua, Augusto A. and Sparrow, David W. and Gulsvik, Amund and Bakke, Per S. and Crapo, James D. and Beaty, Terri H. and Hansel, Nadia N. and Mathias, Rasika A. and Ruczinski, Ingo and Barnes, Kathleen C. and Bossé, Yohan and Joubert, Philippe and van den Berge, Maarten and Brandsma, Corry-Anke and Paré, Peter D. and Sin, Don D. and Nickle, David C. and Hao, Ke and Gottesman, Omri and Dewey, Frederick E. and Bruse, Shannon E. and Carey, David J. and Kirchner, H. Lester and Jonsson, Stefan and Thorleifsson, Gudmar and Jonsdottir, Ingileif and Gislason, Thorarinn and Stefansson, Kari and Schurmann, Claudia and Nadkarni, Girish and Bottinger, Erwin P. and Loos, Ruth J. F. and Walters, Robin G. and Chen, Zhengming and Millwood, Iona Y. and Vaucher, Julien and Kurmi, Om P. and Li, Liming and Hansell, Anna L. and Brightling, Chris and Zeggini, Eleftheria and Cho, Michael H. and Silverman, Edwin K. and Sayers, Ian and Trynka, Gosia and Morris, Andrew P. and Strachan, David P. and Hall, Ian P. and Tobin, Martin D.. (2017) Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature genetics, 49 (3). pp. 416-425.

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