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CD14, new aspects of ligand and signal diversity

Landmann, R. and Muller, B. and Zimmerli, W.. (2000) CD14, new aspects of ligand and signal diversity. Microbes and Infection, 2 (3). pp. 295-304.

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Official URL: http://edoc.unibas.ch/56676/

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Abstract

The glycosyl-phosphatidylinositol-linked glycoprotein CD14 is expressed in myeloid cells and serum. It binds Gram-negative and -positive bacterial cell wall components and endogenous phospholipids. Toll-like receptors, NF-kappaB and MAP kinases participate in CD14 signaling of inflammation. Alterations of CD14 in inflammatory diseases support a pathogenic role for this microbial receptor.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Allgemeine innere Medizin AG > Argovia Professur für Medizin (Müller)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Allgemeine innere Medizin AG > Argovia Professur für Medizin (Müller)
UniBasel Contributors:Müller, Beat
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Publisher:Elsevier
ISSN:1286-4579
e-ISSN:1769-714X
Note:Publication type according to Uni Basel Research Database: Journal item
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Last Modified:17 Nov 2017 12:28
Deposited On:17 Nov 2017 12:28

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