Eckert, A. and Förstl, H. and Hartmann, H. and Czech, C. and Mönning, U. and Beyreuther, K. and Müller, W. E.. (1995) The amplifying effect of beta-amyloid on cellular calcium signalling is reduced in Alzheimer's disease. NeuroReport, Vol. 6, H. 8. pp. 1199-1202.
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Official URL: http://edoc.unibas.ch/dok/A5253515
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Abstract
The amplifying effect of beta-amyloid fragment 25-35 (beta A25-35) on the mitogen-induced rise of free intracellular calcium in circulating lymphocytes was strongly reduced in 24 patients with Alzheimer's disease when compared with elderly, non-demented controls. Low beta-amyloid responses were significantly correlated with the presence of the apolipoprotein E epsilon 4 allele, suggesting a dose effect.
Faculties and Departments: | 03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK |
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UniBasel Contributors: | Eckert, Anne |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
Publisher: | Lippincott Williams & Wilkins |
ISSN: | 0959-4965 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Related URLs: | |
Identification Number: |
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Last Modified: | 22 Mar 2012 14:23 |
Deposited On: | 22 Mar 2012 13:35 |
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