Items where contributor is "Broz, Petr"

Meunier, Etienne and Broz, Petr. (2017) Evolutionary Convergence and Divergence in NLR Function and Structure. Trends in Immunology, 38 (10). pp. 744-757.

Brodmann, Maj and Dreier, Roland F. and Broz, Petr and Basler, Marek. (2017) Francisella requires dynamic type VI secretion system and ClpB to deliver effectors for phagosomal escape. Nature Communications, 8. p. 15853.

Wallet, Pierre and Benaoudia, Sacha and Mosnier, Amandine and Lagrange, Brice and Martin, Amandine and Lindgren, Helena and Golovliov, Igor and Michal, Fanny and Basso, Pauline and Djebali, Sophia and Provost, Angelina and Allatif, Omran and Meunier, Etienne and Broz, Petr and Yamamoto, Masahiro and Py, Bénédicte F. and Faudry, Eric and Sjöstedt, Anders and Henry, Thomas. (2017) IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection. PLoS Pathogens, 13 (10). e1006630.

Sborgi, Lorenzo and Rühl, Sebastian and Mulvihill, Estefania and Pipercevic, Joka and Heilig, Rosalie and Stahlberg, Henning and Farady, Christopher J. and Müller, Daniel J. and Broz, Petr and Hiller, Sebastian. (2016) GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death. The EMBO Journal, 35 (16). pp. 1766-1778.

Di Micco, Antonia and Frera, Gianluca and Lugrin, Jérôme and Jamilloux, Yvan and Hsu, Erh-Ting and Tardivel, Aubry and De Gassart, Aude and Zaffalon, Léa and Bujisic, Bojan and Siegert, Stefanie and Quadroni, Manfredo and Broz, Petr and Henry, Thomas and Hrycyna, Christine A. and Martinon, Fabio. (2016) AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity. Proceedings of the National Academy of Sciences of the United States of America, 113 (32). E4671-E4680.

Broz, Petr. (2016) Inflammasomes: Intracellular detection of extracellular bacteria. Cell research, 26 (8). pp. 859-860.

Broz, Petr and Dixit, Vishva M.. (2016) Inflammasomes: mechanism of assembly, regulation and signalling. Nature reviews. Immunology, 16 (7). pp. 407-420.

Meunier, Etienne and Broz, Petr. (2016) Interferon-inducible GTPases in cell autonomous and innate immunity. Cellular microbiology, 18 (2). pp. 168-180.

Broz, Petr. (2016) Immune Response: Intracellular pathogens under attack. eLife, 5. e14729.

Dick, Mathias S. and Sborgi, Lorenzo and Rühl, Sebastian and Hiller, Sebastian and Broz, Petr. (2016) ASC filament formation serves as a signal amplification mechanism for inflammasomes. Nature Communications, 7. p. 11929.

Rühl, Sebastian and Broz, Petr. (2016) The gasdermin-D pore: Executor of pyroptotic cell death. Oncotarget, 7 (36). pp. 57481-57482.

Groß, Christina J. and Mishra, Ritu and Schneider, Katharina S. and Médard, Guillaume and Wettmarshausen, Jennifer and Dittlein, Daniela C. and Shi, Hexin and Gorka, Oliver and Koenig, Paul-Albert and Fromm, Stephan and Magnani, Giovanni and Ćiković, Tamara and Hartjes, Lara and Smollich, Joachim and Robertson, Avril A. B. and Cooper, Matthew A. and Schmidt-Supprian, Marc and Schuster, Michael and Schroder, Kate and Broz, Petr and Traidl-Hoffmann, Claudia and Beutler, Bruce and Kuster, Bernhard and Ruland, Jürgen and Schneider, Sabine and Perocchi, Fabiana and Groß, Olaf. (2016) K(+) Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria. Immunity, 45 (4). pp. 761-773.

Ravotti, Francesco and Sborgi, Lorenzo and Cadalbert, Riccardo and Huber, Matthias and Mazur, Adam and Broz, Petr and Hiller, Sebastian and Meier, Beat H. and Böckmann, Anja. (2016) Sequence-specific solid-state NMR assignments of the mouse ASC PYRIN domain in its filament form. Biomolecular NMR Assignments, 10 (1). pp. 107-115.

Broz, Petr. (2016) Inflammasomes in Host Defense and Autoimmunity. Chimia, 70 (12). pp. 853-855.

Broz, Petr. (2015) Inflammasome assembly: the wheels are turning. Cell research, 25 (12). pp. 1277-1278.

Broz, Petr. (2015) Immunology: Caspase target drives pyroptosis. Nature, 526. pp. 642-643.

Sborgi, Lorenzo and Ravotti, Francesco and Dandey, Venkata Prasad and Dick, Mathias S. and Mazur, Adam and Reckel, Sina and Chami, Mohamed and Scherer, Sebastian and Huber, Matthias and Böckmann, Anja and Egelman, Edward H. and Stahlberg, Henning and Broz, Petr and Meier, Beat H. and Hiller, Sebastian. (2015) Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 112 (43). pp. 13237-13242.

Rühl, Sebastian and Broz, Petr. (2015) Caspase-11 activates a canonical NLRP3 inflammasome by promoting K+ efflux. European journal of immunology, 45 (10). pp. 2927-2936.

Meunier, Etienne and Broz, Petr. (2015) Interferon-induced guanylate-binding proteins promote cytosolic lipopolysaccharide detection by caspase-11. DNA and cell biology, Vol. 34, H. 1. pp. 1-5.

Meunier, Etienne and Wallet, Pierre and Dreier, Roland F. and Costanzo, Stéphanie and Anton, Leonie and Rühl, Sebastian and Dussurgey, Sébastien and Dick, Mathias S. and Kistner, Anne and Rigard, Mélanie and Degrandi, Daniel and Pfeffer, Klaus and Yamamoto, Masahiro and Henry, Thomas and Broz, Petr. (2015) Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida. Nature immunology, Vol. 16, H. 5. pp. 476-484.

Meunier, Etienne and Broz, Petr. (2015) Quantification of Cytosolic vs. Vacuolar Salmonella in Primary Macrophages by Differential Permeabilization. Journal of visualized experiments, H. 101 , e52960.

O'Donnell, Hope and Pham, Oanh H. and Li, Lin-Xi and Atif, Shaikh M. and Lee, Seung-Joo and Ravesloot, Marietta M. and Stolfi, Jessica L. and Nuccio, Sean-Paul and Broz, Petr and Monack, Denise M. and Baumler, Andreas J. and McSorley, Stephen J.. (2014) Toll-like Receptor and Inflammasome Signals Converge to Amplify the Innate Bactericidal Capacity of T Helper 1 Cells. Immunity, Vol. 40, H. 2. pp. 213-224.

Meunier, Etienne and Dick, Mathias S. and Dreier, Roland F. and Schürmann, Nura and Kenzelmann Broz, Daniela and Warming, Søren and Roose-Girma, Merone and Bumann, Dirk and Kayagaki, Nobuhiko and Takeda, Kiyoshi and Yamamoto, Masahiro and Broz, Petr. (2014) Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. Nature, 509 (7500). pp. 366-370.

Broz, Petr. (2014) Getting rid of the bad apple : inflammasome-induced extrusion of salmonella-infected enterocytes. Cell host & microbe, Vol. 16, H. 2. pp. 153-155.

Broz, Petr and Monack, Denise M.. (2013) Newly described pattern recognition receptors team up against intracellular pathogens. Nature reviews. Immunology, Vol. 13, H. 8. pp. 551-652.

Xiao, Junpeng and Broz, Petr and Puri, Aaron W. and Deu, Edgar and Morell, Montse and Monack, Denise M. and Bogyo, Matthew. (2013) A coupled protein and probe engineering approach for selective inhibition and activity-based probe labeling of the caspases. Journal of the American Chemical Society, Vol. 135, H. 24. pp. 9130-9138.

Broz, Petr and Monack, Denise M.. (2013) Noncanonical inflammasomes: caspase-11 activation and effector mechanisms. PLoS Pathogens, 9 (2). e1003144.

Juruj, C. and Lelogeais, V. and Pierini, R. and Perret, M. and Py, B. F. and Jamilloux, Y. and Broz, P. and Ader, F. and Faure, M. and Henry, T.. (2013) Caspase-1 activity affects AIM2 speck formation/stability through a negative feedback loop. Frontiers in Cellular and Infection Microbiology, 3. p. 14.

Broz, Petr and Monack, Denise M.. (2013) Measuring Inflammasome Activation in Response to Bacterial Infection. Methods in Molecular Biology, 1040. pp. 65-84.

Broz, Petr and Ruby, Thomas and Belhocine, Kamila and Bouley, Donna M. and Kayagaki, Nobuhiko and Dixit, Vishva M. and Monack, Denise M.. (2012) Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature, 490 (7419). pp. 288-291.

Puri, Aaron W. and Broz, Petr and Shen, Aimee and Monack, Denise M. and Bogyo, Matthew. (2012) Caspase-1 activity is required to bypass macrophage apoptosis upon Salmonella infection. Nature Chemical Biology, 8 (9). pp. 745-747.

Broz, Petr and Ohlson, Maikke B. and Monack, Denise M.. (2012) Innate immune response to Salmonella typhimurium, a model enteric pathogen. Gut microbes, 3 (2). pp. 62-70.

Broz, Petr and Monack, Denise M.. (2011) Molecular mechanisms of inflammasome activation during microbial infections. Immunological Reviews, 243 (1). pp. 174-190.

Peng, Kaitian and Broz, Petr and Jones, Jonathan and Joubert, Lydia-Marie and Monack, Denise. (2011) Elevated AIM2-mediated pyroptosis triggered by hypercytotoxic Francisella mutant strains is attributed to increased intracellular bacteriolysis. Cellular Microbiology, 13 (10). pp. 1586-1600.

Jones, Jonathan Wiley and Broz, Petr and Monack, Denise M.. (2011) Innate immune recognition of francisella tularensis: activation of type-I interferons and the inflammasome. Frontiers in Microbiology, 2. p. 16.

Broz, Petr and von Moltke, Jakob and Jones, Jonathan W. and Vance, Russell E. and Monack, Denise M.. (2010) Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host & Microbe, 8 (6). pp. 471-483.

Broz, Petr and Newton, Kim and Lamkanfi, Mohamed and Mariathasan, Sanjeev and Dixit, Vishva M. and Monack, Denise M.. (2010) Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. Journal of Experimental Medicine, 207 (8). pp. 1745-1755.

Jones, Jonathan W. and Kayagaki, Nobuhiko and Broz, Petr and Henry, Thomas and Newton, Kim and O'Rourke, Karen and Chan, Salina and Dong, Jennifer and Qu, Yan and Roose-Girma, Meron and Dixit, Vishva M. and Monack, Denise M.. (2010) Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proceedings of the National Academy of Sciences, 107 (21). pp. 9771-9776.

Mueller, C. A. and Broz, P. and Cornelis, G. R.. (2008) The type III secretion system tip complex and translocon. Molecular microbiology, Vol. 68, H. 5. pp. 1085-1095.

Sorg, I. and Wagner, S. and Amstutz, M. and Muller, S. A. and Broz, P. and Lussi, Y. and Engel, A. and Cornelis, G. R.. (2007) YscU recognizes translocators as export substrates of the Yersinia injectisome. The EMBO journal, Vol. 26, H. 12. pp. 3015-3024.

Broz, P. and Mueller, C. A. and Muller, S. A. and Philippsen, A. and Sorg, I. and Engel, A. and Cornelis, G. R.. (2007) Function and molecular architecture of the Yersinia injectisome tip complex. Molecular microbiology, Vol. 65, H. 5. pp. 1311-1320.

Broz, Petr. Functional and structural analysis of the "Yersinia enterocolitica" type III secretion translocon. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Mueller, C. A. and Broz, P. and Muller, S. A. and Ringler, P. and Erne-Brand, F. and Sorg, I. and Kuhn, M. and Engel, A. and Cornelis, G. R.. (2005) The V-antigen of Yersinia forms a distinct structure at the tip of injectisome needles. Science, Vol. 310, H. 5748. pp. 674-676.

Goure, J. and Broz, P. and Attree, O. and Cornelis, G. R. and Attree, I.. (2005) Protective anti-V antibodies inhibit Pseudomonas and Yersinia translocon assembly within host membranes. The Journal of Infectious Diseases, Vol. 192, H. 2. pp. 218-225.

Journet, Laure and Agrain, Céline and Broz, Petr and Cornelis, Guy R.. (2003) The needle length of bacterial injectisomes is determined by a molecular ruler. Science, 302, No. 5651. pp. 1757-1760.