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Items where contributor is "Martin, Ivan"

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2016

Marsano, Anna and Medeiros da Cunha, Carolina M. and Ghanaati, Shahram and Gueven, Sinan and Centola, Matteo and Tsaryk, Roman and Barbeck, Mike and Stuedle, Chiara and Barbero, Andrea and Helmrich, Uta and Schaeren, Stefan and Kirkpatrick, James C. and Banfi, Andrea and Martin, Ivan. (2016) Spontaneous In Vivo Chondrogenesis of Bone Marrow-Derived Mesenchymal Progenitor Cells by Blocking Vascular Endothelial Growth Factor Signaling. Stem cells translational medicine, 5 (12). pp. 1730-1738.

Mumme, Marcus and Barbero, Andrea and Miot, Sylvie and Wixmerten, Anke and Feliciano, Sandra and Wolf, Francine and Asnaghi, Adelaide M. and Baumhoer, Daniel and Bieri, Oliver and Kretzschmar, Martin and Pagenstert, Geert and Haug, Martin and Schaefer, Dirk J. and Martin, Ivan and Jakob, Marcel. (2016) Nasal chondrocyte-based engineered autologous cartilage tissue for repair of articular cartilage defects: an observational first-in-human trial. Lancet, 388 (10055). pp. 1985-1994.

Mumme, Marcus and Steinitz, Amir and Nuss, Katja M. and Klein, Karina and Feliciano, Sandra and Kronen, Peter and Jakob, Marcel and von Rechenberg, Brigitte and Martin, Ivan and Barbero, Andrea and Pelttari, Karoliina. (2016) Regenerative Potential of Tissue-Engineered Nasal Chondrocytes in Goat Articular Cartilage Defects. Tissue Engineering, 22 (21-22). pp. 1286-1295.

Occhetta, Paola and Stüdle, Chiara and Barbero, Andrea and Martin, Ivan. (2016) Learn, simplify and implement: developmental re-engineering strategies for cartilage repair. Swiss medical weekly, 146. w14346.

Boccardo, Stefano and Gaudiello, Emanuele and Melly, Ludovic and Cerino, Giulia and Ricci, Davide and Martin, Ivan and Eckstein, Friedrich and Banfi, Andrea and Marsano, Anna. (2016) Engineered mesenchymal cell-based patches as controlled VEGF delivery systems to induce extrinsic angiogenesis. Acta Biomaterialia, 42. pp. 127-135.

Todorov, Atanas and Kreutz, Matthias and Haumer, Alexander and Scotti, Celeste and Barbero, Andrea and Bourgine, Paul E. and Scherberich, Arnaud and Jaquiery, Claude and Martin, Ivan. (2016) Fat-Derived Stromal Vascular Fraction Cells Enhance the Bone-Forming Capacity of Devitalized Engineered Hypertrophic Cartilage Matrix. Stem cells translational medicine, 5 (12). pp. 1684-1694.

Rossi, Eleonora and Gerges, Irini and Tocchio, Alessandro and Tamplenizza, Margherita and Aprile, Paola and Recordati, Camilla and Martello, Federico and Martin, Ivan and Milani, Paolo and Lenardi, Cristina. (2016) Biologically and mechanically driven design of an RGD-mimetic macroporous foam for adipose tissue engineering applications. Biomaterials, 104. pp. 65-77.

Osinga, Rik and Di Maggio, Nunzia and Todorov, Atanas and Allafi, Nima and Barbero, Andrea and Laurent, Frédéric and Schaefer, Dirk Johannes and Martin, Ivan and Scherberich, Arnaud. (2016) Generation of a Bone Organ by Human Adipose-Derived Stromal Cells Through Endochondral Ossification. Stem cells translational medicine, 5 (8). pp. 1090-1097.

Müller, Sebastian and Acevedo, Lina and Wang, Xiaomei and Karim, M. Zia and Matta, Ajay and Mehrkens, Arne and Schaeren, Stefan and Feliciano, Sandra and Jakob, Marcel and Martin, Ivan and Barbero, Andrea and Erwin, W. Mark. (2016) Notochordal cell conditioned medium (NCCM) regenerates end-stage human osteoarthritic articular chondrocytes and promotes a healthy phenotype. Arthritis Research and Therapy, 18 (1). p. 125.

Scotti, Celeste and Tonnarelli, Beatrice and Papadimitropoulos, Adam and Piccinini, Elia and Todorov, Atanas and Centola, Matteo and Barbero, Andrea and Martin, Ivan. (2016) Engineering Small-Scale and Scaffold-Based Bone Organs via Endochondral Ossification Using Adult Progenitor Cells. Methods in Molecular Biology, 1416. pp. 413-424.

Martin, Ivan and De Boer, Jan and Sensebe, Luc and Committee of the International Society for Cellular Therapy, M. S. C.. (2016) A relativity concept in mesenchymal stromal cell manufacturing. Cytotherapy, 18 (5). pp. 613-620.

Galipeau, Jacques and Krampera, Mauro and Barrett, John and Dazzi, Francesco and Deans, Robert J. and DeBruijn, Joost and Dominici, Massimo and Fibbe, Willem E. and Gee, Adrian P. and Gimble, Jeffery M. and Hematti, Peiman and Koh, Mickey B. C. and LeBlanc, Katarina and Martin, Ivan and McNiece, Ian K. and Mendicino, Michael and Oh, Steve and Ortiz, Luis and Phinney, Donald G. and Planat, Valerie and Shi, Yufang and Stroncek, David F. and Viswanathan, Sowmya and Weiss, Daniel J. and Sensebe, Luc. (2016) International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials. Cytotherapy, 18 (2). pp. 151-159.

Blache, Ulrich and Metzger, Stéphanie and Vallmajo-Martin, Queralt and Martin, Ivan and Djonov, Valentin and Ehrbar, Martin. (2016) Dual Role of Mesenchymal Stem Cells Allows for Microvascularized Bone Tissue-Like Environments in PEG Hydrogels. Advanced Healthcare Materials, 5 (4). pp. 489-498.

Martin, Ivan and Ireland, Hilary and Baldomero, Helen and Dominici, Massimo and Saris, Daniël B. and Passweg, Jakob. (2016) The Survey on Cellular and Engineered Tissue Therapies in Europe in 2013. Tissue Engineering, 22 (1-2). pp. 5-16.

Klar, Agnes S. and Güven, Sinan and Zimoch, Jakub and Zapiórkowska, Natalia A. and Biedermann, Thomas and Böttcher-Haberzeth, Sophie and Meuli-Simmen, Claudia and Martin, Ivan and Scherberich, Arnaud and Reichmann, Ernst and Meuli, Martin. (2016) Characterization of vasculogenic potential of human adipose-derived endothelial cells in a three-dimensional vascularized skin substitute. Pediatric surgery international, 32 (1). pp. 17-27.

Bersini, Simone and Arrigoni, Chiara and Lopa, Silvia and Bongio, Matilde and Martin, Ivan and Moretti, Matteo. (2016) Engineered miniaturized models of musculoskeletal diseases. Drug Discovery Today, 21 (9). pp. 1429-1436.

Martin, Ivan and Duhr, Ralph. (2016) Future of cellular therapies in orthopaedics: Different views, one common challenge. Journal of Orthopaedic Research, 34 (1). pp. 10-11.

Scotti, Celeste and Gobbi, Alberto and Karnatzikos, Georgios and Martin, Ivan and Shimomura, Kazunori and Lane, John G. and Peretti, Giuseppe Michele and Nakamura, Norimasa. (2016) Cartilage Repair in the Inflamed Joint: Considerations for Biological Augmentation Toward Tissue Regeneration. Tissue Engineering, 22 (2). pp. 149-159.

Cerino, Giulia and Gaudiello, Emanuele and Grussenmeyer, Thomas and Melly, Ludovic and Massai, Diana and Banfi, Andrea and Martin, Ivan and Eckstein, Friedrich and Grapow, Martin and Marsano, Anna. (2016) Three dimensional multi-cellular muscle-like tissue engineering in perfusion-based bioreactors. Biotechnology and Bioengineering, 113 (1). pp. 226-236.

Klar, Agnes S. and Güven, Sinan and Zimoch, Jakub and Zapiórkowska, Natalia A. and Biedermann, Thomas and Böttcher-Haberzeth, Sophie and Meuli-Simmen, Claudia and Martin, Ivan and Scherberich, Arnaud and Reichmann, Ernst and Meuli, Martin. (2016) Characterization of vasculogenic potential of human adipose-derived endothelial cells in a three-dimensional vascularized skin substitute. Pediatric Surgery International, 32 (1). pp. 17-27.

Asnaghi, Adelaide M. and Miot, Sylvie and Wixmerten, Anke and Martin, Ivan. (2016) Successes and hurdles in the translation of tissue engineered products for cartilage repair in clinical trials: focus on regulatory perspectives. European cells & materials, 31 (Suppl. 1). p. 172.

2015

Sabatino, Maria Antonietta and Santoro, Rosaria and Gueven, Sinan and Jaquiery, Claude and Wendt, David J. and Martin, Ivan and Moretti, Matteo and Barbero, Andrea. (2015) Cartilage graft engineering by co-culturing primary human articular chondrocytes with human bone marrow stromal cells. Journal of tissue engineering and regenerative medicine, 9 (12). pp. 1394-1403.

Müller, Sebastian A. and Todorov, Atanas and Heisterbach, Patricia E. and Martin, Ivan and Majewski, Martin. (2015) Tendon healing: an overview of physiology, biology, and pathology of tendon healing and systematic review of state of the art in tendon bioengineering. Knee surgery, sports traumatology, arthroscopy, 23 (7). pp. 2097-2105.

Deponti, D. and Giancamillo, A. D. and Scotti, C. and Peretti, G. M. and Martin, I.. (2015) Animal models for meniscus repair and regeneration. Journal of tissue engineering and regenerative medicine, Vol. 9, H. 5. pp. 512-527.

2014

Mehrkens, A. and Di Maggio, N. and Gueven, S. and Schaefer, D. and Scherberich, A. and Banfi, A. and Martin, I.. (2014) Non-adherent mesenchymal progenitors from adipose tissue stromal vascular fraction. Tissue Engineering, 20 (5-6). pp. 1081-1088.

Martin, I. and Baldomero, H. and Bocelli-Tyndall, C. and Emmert, M. Y. and Hoerstrup, S. P. and Ireland, H. and Passweg, J. and Tyndall, A.. (2014) The Survey on Cellular and Engineered Tissue Therapies in Europe in 2011. Tissue engineering. Part A, Vol. 20, H. 3-4. pp. 842-853.

Mele, V. and Muraro, M. G. and Calabrese, D. and Pfaff, D. and Amatruda, N. and Amicarella, F. and Kvinlaug, B. and Bocelli-Tyndall, C. and Martin, I. and Resink, T. J. and Heberer, M. and Oertli, D. and Terracciano, L. and Spagnoli, G. C. and Iezzi, G.. (2014) Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-beta. International journal of cancer, Vol. 134, H. 11. pp. 2583-2594.

2013

Helmrich, U. and Di Maggio, N. and Guven, S. and Groppa, E. and Melly, L. and Largo, R. D. and Heberer, M. and Martin, I. and Scherberich, A. and Banfi, A.. (2013) Osteogenic graft vascularization and bone resorption by VEGF-expressing human mesenchymal progenitors. Biomaterials, 34 (21). pp. 5025-5035.

Bhattacharjee, M. and Schultz-Thater, E. and Trella, E. and Miot, S. and Das, S. and Loparic, M. and Ray, A. R. and Martin, I. and Spagnoli, G. C. and Ghosh, S.. (2013) The role of 3D structure and protein conformation on the innate and adaptive immune responses to silk-based biomaterials. Biomaterials, Vol. 34, no. 33. pp. 8161-8171.

Centola, M. and Tonnarelli, B. and Scharen, S. and Glaser, N. and Barbero, A. and Martin, I.. (2013) Priming 3D cultures of human mesenchymal stromal cells toward cartilage formation via developmental pathways. Stem cells and development, Vol. 22, H. 21. pp. 2849-2858.

Scotti, C. and Piccinini, E. and Takizawa, H. and Todorov, A. and Bourgine, P. and Papadimitropoulos, A. and Barbero, A. and Manz, M. G. and Martin, I.. (2013) Engineering of a functional bone organ through endochondral ossification. Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, H. 10. pp. 3997-4002.

Bourgine, P. E. and Pippenger, B. E. and Todorov, A. and Jr., and Tchang, L. and Martin, I.. (2013) Tissue decellularization by activation of programmed cell death. Biomaterials, Vol. 34, no. 26. pp. 6099-6108.

Centola, M. and Abbruzzese, F. and Scotti, C. and Barbero, A. and Vadala, G. and Denaro, V. and Martin, I. and Trombetta, M. and Rainer, A. and Marsano, A.. (2013) Scaffold-based delivery of a clinically relevant anti-angiogenic drug promotes the formation of in vivo stable cartilage. Tissue engineering. Part A, Vol. 19, H. 17-18. pp. 1960-1971.

Phinney, D. G. and Galipeau, J. and Krampera, M. and Martin, I. and Shi, Y. and Sensebe, L.. (2013) MSCs: science and trials. Nature medicine, Vol. 19, H. 7. p. 812.

Scotti, C. and Hirschmann, M. T. and Antinolfi, P. and Martin, I. and Peretti, G. M.. (2013) Meniscus repair and regeneration : review on current methods and research potential. European cells & materials, Vol. 26. pp. 150-170.

Papadimitropoulos, A. and Riboldi, S. A. and Tonnarelli, B. and Piccinini, E. and Woodruff, M. A. and Hutmacher, D. W. and Martin, I.. (2013) A collagen network phase improves cell seeding of open-pore structure scaffolds under perfusion. Journal of tissue engineering and regenerative medicine, Vol. 7, H. 3. pp. 183-191.

Fulco, I. and Largo, R. D. and Miot, S. and Wixmerten, A. and Martin, I. and Schaefer, D. J. and Haug, M. D.. (2013) Toward clinical application of tissue-engineered cartilage. Facial plastic surgery, Vol. 29, no. 2. pp. 99-105.

2012

Helmrich, U. and Marsano, A. and Melly, L. and Wolff, T. and Christ, L. and Heberer, M. and Scherberich, A. and Martin, I. and Banfi, A.. (2012) Generation of human adult mesenchymal stromal/stem cells expressing defined xenogenic vascular endothelial growth factor levels by optimized transduction and flow cytometry purification. Tissue engineering. Part C, Methods, Vol. 18, H. 4. pp. 283-292.

Acharya, Chitrangada and Adesida, Adetola and Zajac, Paul and Mumme, Marcus and Riesle, Jens and Martin, Ivan and Barbero, Andrea. (2012) Enhanced chondrocyte proliferation and mesenchymal stromal cells chondrogenesis in coculture pellets mediate improved cartilage formation. Journal of cellular physiology, Vol. 227, no. 1. pp. 88-97.

Scotti, Celeste and Osmokrovic, Andrea and Wolf, Francine and Miot, Sylvie and Peretti, Giuseppe M. and Barbero, Andrea and Martin, Ivan. (2012) Response of human engineered cartilage based on articular or nasal chondrocytes to interleukin-1? and low oxygen. Tissue engineering. Part A, Vol. 18, H. 3-4. pp. 362-372.

Di Maggio, Nunzia and Mehrkens, Arne and Papadimitropoulos, Adam and Schaeren, Stefan and Heberer, Michael and Banfi, Andrea and Martin, Ivan. (2012) Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c. Stem cells, Vol. 30, H. 7. pp. 1455-1464.

Jakob, M. and Saxer, F. and Scotti, C. and Schreiner, S. and Studer, P. and Scherberich, A. and Heberer, M. and Martin, I.. (2012) Perspective on the evolution of cell-based bone tissue engineering strategies. European Surgical Research, 49 (1). pp. 1-7.

Sadr, N. and Pippenger, B. E. and Scherberich, A. and Wendt, D. and Mantero, S. and Martin, I. and Papadimitropoulos, A.. (2012) Enhancing the biological performance of synthetic polymeric materials by decoration with engineered, decellularized extracellular matrix. Biomaterials, 33 (20). pp. 5085-5093.

Sensebe, L. and Tarte, K. and Galipeau, J. and Krampera, M. and Martin, I. and Phinney, D. G. and Shi, Y.. (2012) Limited acquisition of chromosomal aberrations in human adult mesenchymal stromal cells. Cell stem cell, Vol. 10, H. 1. pp. 9-10.

Kon, E. and Filardo, G. and Tschon, M. and Fini, M. and Giavaresi, G. and Marchesini Reggiani, L. and Chiari, C. and Nehrer, S. and Martin, I. and Salter, D. M. and Ambrosio, L. and Marcacci, M.. (2012) Tissue engineering for total meniscal substitution: animal study in sheep model : results at 12 months. Tissue engineering. Part A, Vol. 18, H. 15-16. pp. 1573-1582.

Miot, S. and Brehm, W. and Dickinson, S. and Sims, T. and Wixmerten, A. and Longinotti, C. and Hollander, A. P. and Mainil-Varlet, P. and Martin, I.. (2012) Influence of in vitro maturation of engineered cartilage on the outcome of osteochondral repair in a goat model. European cells & materials, Vol. 23. pp. 222-236.

Mehrkens, A. and Saxer, F. and Guven, S. and Hoffmann, W. and Muller, A. M. and Jakob, M. and Weber, F. E. and Martin, I. and Scherberich, A.. (2012) Intraoperative engineering of osteogenic grafts combining freshly harvested, human adipose-derived cells and physiological doses of bone morphogenetic protein-2. European cells & materials, 24. pp. 308-319.

Guven, S. and Karagianni, M. and Schwalbe, M. and Schreiner, S. and Farhadi, J. and Bula, S. and Bieback, K. and Martin, I. and Scherberich, A.. (2012) Validation of an automated procedure to isolate human adipose tissue-derived cells by using the Sepax(R) technology. Tissue engineering. Part C, Vol. 18, H. 8. pp. 575-582.

Sorensen, J. R. and Koroma, K. E. and Ding, M. and Wendt, D. and Jespersen, S. and Juhl, M. V. and Theilgaard, N. and Martin, I. and Overgaard, S.. (2012) Effects of a perfusion bioreactor activated novel bone substitute in spine fusion in sheep. European spine journal, Vol. 21, H. 9. pp. 1740-1747.

Bhattacharjee, M. and Miot, S. and Gorecka, A. and Singha, K. and Loparic, M. and Dickinson, S. and Das, A. and Bhavesh, N. S. and Ray, A. R. and Martin, I. and Ghosh, S.. (2012) Oriented lamellar silk fibrous scaffolds to drive cartilage matrix orientation : towards annulus fibrosus tissue engineering. Acta Biomaterialia, Vol. 8, H. 9. pp. 3313-3325.

Mumme, M. and Scotti, C. and Papadimitropoulos, A. and Todorov, A. and Hoffmann, W. and Bocelli-Tyndall, C. and Jakob, M. and Wendt, D. and Martin, I. and Barbero, A.. (2012) Interleukin-1beta modulates endochondral ossification by human adult bone marrow stromal cells. European cells & materials, Vol. 24. pp. 224-236.

Martin, I. and Baldomero, H. and Bocelli-Tyndall, C. and Passweg, J. and Saris, D. and Tyndall, A.. (2012) The survey on cellular and engineered tissue therapies in Europe in 2010. Tissue engineering. Part A, Vol. 18, H. 21-22. pp. 2268-2279.

Santoro, R. and Krause, C. and Martin, I. and Wendt, D.. (2012) On-line monitoring of oxygen as a non-destructive method to quantify cells in engineered 3D tissue constructs. Journal of tissue engineering and regenerative medicine, Vol. 6, H. 9 , S. 696–701.

2011

Grote, M. J. and Palumberi, V. and Wagner, B. and Barbero, A. and Martin, I.. (2011) Dynamic formation of oriented patches in chondrocyte cell cultures. Journal of mathematical biology, Vol. 63, H. 4. pp. 757-777.

Toni, Roberto and Tampieri, Anna and Zini, Nicoletta and Strusi, Valentina and Sandri, Monica and Dallatana, Davide and Spaletta, Giulia and Bassoli, Elena and Gatto, Andrea and Ferrari, Andrea and Martin, Ivan. (2011) Ex situ bioengineering of bioartificial endocrine glands : a new frontier in regenerative medicine of soft tissue organs. Annals of anatomy, Vol. 193, no. 5. pp. 381-394.

Rouwkema, Jeroen and Gibbs, Susan and Lutolf, Matthias P. and Martin, Ivan and Vunjak-Novakovic, Gordana and Malda, Jos. (2011) In vitro platforms for tissue engineering : implications for basic research and clinical translation. Journal of tissue engineering and regenerative medicine, Vol. 5, H. 8 , e164-e167.

Güven, Sinan and Mehrkens, Arne and Saxer, Franziska and Schaefer, Dirk J. and Martinetti, Roberta and Martin, Ivan and Scherberich, Arnaud. (2011) Engineering of large osteogenic grafts with rapid engraftment capacity using mesenchymal and endothelial progenitors from human adipose tissue. Biomaterials, 32 (25). pp. 5801-5809.

Papadimitropoulos, Adam and Scherberich, Arnaud and Güven, Sinan and Theilgaard, Naseem and Crooijmans, Hendrikus J. A. and Santini, Francesco and Scheffler, Klaus and Zallone, Alberta and Martin, Ivan. (2011) A 3D in vitro bone organ model using human progenitor cells. European cells & materials, Vol. 21 , S. 445-458, discussion 458.

Santoro, R. and Braissant, O. and Müller, B. and Wirz, D. and Daniels, A. U. and Martin, I. and Wendt, D.. (2011) Real-time measurements of human chondrocyte heat production during in vitro proliferation. Biotechnology and bioengineering, Vol. 108, no. 12. pp. 3019-3024.

Melchels, Ferry P. W. and Tonnarelli, Beatrice and Olivares, Andy L. and Martin, Ivan and Lacroix, Damien and Feijen, Jan and Wendt, David J. and Grijpma, Dirk W.. (2011) The influence of the scaffold design on the distribution of adhering cells after perfusion cell seeding. Biomaterials, Vol. 32, no. 11. pp. 2878-2884.

Di Maggio, N. and Piccinini, E. and Jaworski, M. and Trumpp, A. and Wendt, D. J. and Martin, I.. (2011) Toward modeling the bone marrow niche using scaffold-based 3D culture systems. Biomaterials, Vol. 32, no. 2. pp. 321-329.

Francioli, Silvia and Cavallo, Carola and Grigolo, Brunella and Martin, Ivan and Barbero, Andrea. (2011) Engineered cartilage maturation regulates cytokine production and interleukin-1beta response. Clinical orthopaedics and related research, Vol. 469, H. 10. pp. 2773-2784.

Martin, I. and Baldomero, H. and Bocelli-Tyndall, C. and Slaper-Cortenbach, I. and Passweg, J. and Tyndall, A.. (2011) The survey on cellular and engineered tissue therapies in Europe in 2009. Tissue engineering. Part A, Vol. 17, H. 17-18. pp. 2221-2230.

2010

Loparic, M. and Wirz, D. and Daniels, A. U. and Raiteri, R. and Vanlandingham, M. R. and Guex, G. and Martin, I. and Aebi, U. and Stolz, M.. (2010) Micro- and nanomechanical analysis of articular cartilage by indentation-type atomic force microscopy: validation with a gel-microfiber composite. Biophysical journal, Vol. 98. pp. 2731-2740.

Vonwil, Daniel and Schuler, Martin and Barbero, Andrea and Ströbel, Simon and Wendt, David and Textor, Marcus and Aebi, Ueli and Martin, Ivan. (2010) An RGD-restricted substrate interface is sufficient for the adhesion, growth and cartilage forming capacity of human chondrocytes. European cells & materials, Vol. 20. pp. 316-328.

Francioli, Silvia E. and Candrian, Christian and Martin, Katja and Heberer, Michael and Martin, Ivan and Barbero, Andrea. (2010) Effect of three-dimensional expansion and cell seeding density on the cartilage-forming capacity of human articular chondrocytes in type II collagen sponges. Journal of biomedical materials research. Part A, Vol. 95, no. 3. pp. 924-931.

Martin, Ivan and Baldomero, Helen and Tyndall, Alan and Niederwieser, Dietger and Gratwohl, Alois. (2010) A survey on cellular and engineered tissue therapies in Europe in 2008. Tissue engineering. Part A, Vol. 16, H. 8. pp. 2419-2427.

Ströbel, Simon and Loparic, Marko and Wendt, David and Schenk, Andreas D. and Candrian, Christian and Lindberg, Raija L. P. and Moldovan, Florina and Barbero, Andrea and Martin, Ivan. (2010) Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages. Arthritis research & therapy, Vol. 12 , R34.

Piccinini, E. and Sadr, N. and Martin, I.. (2010) Ceramic materials lead to underestimated DNA quantifications : a method for reliable measurements. European cells & materials, 20. pp. 38-44.

Miot, Sylvie and Gianni-Barrera, Roberto and Pelttari, Karoliina and Acharya, Chitrangada and Mainil-Varlet, Pierre and Juelke, Henriette and Jaquiery, Claude and Candrian, Christian and Barbero, Andrea and Martin, Ivan. (2010) In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction. Tissue engineering. Part C, Methods, Vol. 16, H. 1. pp. 11-21.

Santoro, Rosaria and Olivares, Andy L. and Brans, Gerben and Wirz, Dieter and Longinotti, Cristina and Lacroix, Damien and Martin, Ivan and Wendt, David. (2010) Bioreactor based engineering of large-scale human cartilage grafts for joint resurfacing. Biomaterials, 31 (34). pp. 8946-8952.

Kon, Elizaveta and Delcogliano, Marco and Filardo, Giuseppe and Fini, Milena and Giavaresi, Gianluca and Francioli, Silvia and Martin, Ivan and Pressato, Daniele and Arcangeli, Elena and Quarto, Rodolfo and Sandri, Monica and Marcacci, Maurillo. (2010) Orderly osteochondral regeneration in a sheep model using a novel nano-composite multilayered biomaterial. Journal of orthopaedic research, Vol. 28, H. 1. pp. 116-124.

Candrian, C. and Miot, S. and Wolf, F. and Bonacina, E. and Dickinson, S. and Wirz, D. and Jakob, M. and Valderrabano, V. and Barbero, A. and Martin, I.. (2010) Are ankle chondrocytes from damaged fragments a suitable cell source for cartilage repair? Osteoarthritis and cartilage, Vol. 18, H. 8. pp. 1067-1076.

Kon, Elizaveta and Filardo, Giuseppe and Delcogliano, Marco and Fini, Milena and Salamanna, Francesca and Giavaresi, Gianluca and Martin, Ivan and Marcacci, Maurilio. (2010) Platelet autologous growth factors decrease the osteochondral regeneration capability of a collagen-hydroxyapatite scaffold in a sheep model. BMC musculoskeletal disorders, Vol. 11. p. 220.

Martin, I. and Riboldi, S. A. and Jakob, M. and Wendt, D.. (2010) SnapShot: bioreactors systems in tissue engineering (TE) & regenerative medicine (RM). Biomaterials, Vol. 31, no. 11. pp. 3114-3115.

Müller, A. M. and Mehrkens, A. and Schäfer, D. J. and Jaquiery, C. and Güven, S. and Lehmicke, M. and Martinetti, R. and Farhadi, I. and Jakob, M. and Scherberich, A. and Martin, I.. (2010) Towards an intraoperative engineering of osteogenic and vasculogenic grafts from the stromal vascular fraction of human adipose tissue. European Cells and Materials, 19. pp. 127-135.

Scotti, Celeste and Wirz, Dieter and Wolf, Francine and Schaefer, Dirk J. and Bürgin, Vivienne and Daniels, Alma U. and Valderrabano, Victor and Candrian, Christian and Jakob, Marcel and Martin, Ivan and Barbero, Andrea. (2010) Engineering human cell-based, functionally integrated osteochondral grafts by biological bonding of engineered cartilage tissues to bony scaffolds. Biomaterials, 31 (8). pp. 2252-2259.

Schaeren, Stefan and Jaquiéry, Claude and Wolf, Francine and Papadimitropoulos, Adam and Barbero, Andrea and Schultz-Thater, Elke and Heberer, Michael and Martin, Ivan. (2010) Effect of bone sialoprotein coating of ceramic and synthetic polymer materials on in vitro osteogenic cell differentiation and in vivo bone formation. Journal of biomedical materials research. Part A, Vol. 92, no. 4. pp. 1461-1467.

Scotti, Celeste and Tonnarelli, Beatrice and Papadimitropoulos, Adam and Scherberich, Arnaud and Schaeren, Stefan and Schauerte, Alexandra and Lopez-Rios, Javier and Zeller, Rolf and Barbero, Andrea and Martin, Ivan. (2010) Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering. Proceedings of the National Academy of Sciences, 107 (16). pp. 7251-7256.

Bocelli-Tyndall, Chiara and Zajac, Paul and Di Maggio, Nunzia and Trella, Emanuele and Benvenuto, Federica and Iezzi, Giandomenica and Scherberich, Arnaud and Barbero, Andrea and Schaeren, Stefan and Pistoia, Vito and Spagnoli, Giulio and Vukcevic, Mirko and Martin, Ivan and Tyndall, Alan. (2010) Fibroblast growth factor 2 and platelet-derived growth factor, but not platelet lysate, induce proliferation-dependent, functional class II major histocompatibility complex antigen in human mesenchymal stem cells. Arthritis & Rheumatism, 62 (12). pp. 3815-3825.

Scherberich, Arnaud and Müller, Andreas M. and Schäfer, Dirk J. and Banfi, Andrea and Martin, Ivan. (2010) Adipose tissue-derived progenitors for engineering osteogenic and vasculogenic grafts. Journal of Cellular Physiology, 225 (2). pp. 348-353.

2009

Stolz, Martin and Gottardi, Riccardo and Raiteri, Roberto and Miot, Sylvie and Martin, Ivan and Imer, Raphael and Staufer, Urs and Raducanu, Aurelia and Dueggelin, Marcel and Baschong, Werner and Daniels, A. U. and Friederich, Niklaus F. and Aszodi, Attila and Aebi, Ueli. (2009) Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy. Nature nanotechnology, Vol. 4. pp. 186-192.

Müller, Andreas M. and Davenport, Michael and Verrier, Sophie and Droeser, Raoul and Alini, Mauro and Bocelli-Tyndall, Chiara and Schaefer, Dirk J. and Martin, Ivan and Scherberich, Arnaud. (2009) Platelet lysate as a serum substitute for 2D static and 3D perfusion culture of stromal vascular fraction cells from human adipose tissue. Tissue engineering. Part A, Vol. 15, H. 4. pp. 869-875.

Montjovent, Marc-Olivier and Bocelli-Tyndall, Chiara and Scaletta, Corinne and Scherberich, Arnaud and Mark, Silke and Martin, Ivan and Applegate, Lee Ann and Pioletti, Dominique P.. (2009) In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications. Tissue engineering. Part A, Vol. 15, H. 7. pp. 1523-1532.

Leumann, A. and Wiewiorski, M. and Egelhof, T. and Rasch, H. and Magerkurth, O. and Candrian, C. and Schaefer, D. J. and Martin, I. and Jakob, M. and Valderrabano, V.. (2009) Radiographic evaluation of frontal talar edge configuration for osteochondral plug transplantation. Clinical anatomy, Vol. 22. pp. 261-266.

Kossowska-Tomaszczuk, Katarzyna and De Geyter, Christian and De Geyter, Maria and Martin, Ivan and Holzgreve, Wolfgang and Scherberich, Arnaud and Zhang, Hong. (2009) The multipotency of luteinizing granulosa cells collected from mature ovarian follicles. Stem Cells, 27 (1). pp. 210-219.

Candrian, C. and Bonacina, E. and Frueh, J. A. and Vonwil, D. and Dickinson, S. and Wirz, D. and Heberer, M. and Jakob, M. and Martin, I. and Barbero, A.. (2009) Intra-individual comparison of human ankle and knee chondrocytes in vitro: relevance for talar cartilage repair. Osteoarthritis and cartilage, Vol. 17. pp. 489-496.

Wendt, D. and Riboldi, S. A. and Cioffi, M. and Martin, I.. (2009) Bioreactors in tissue engineering: scientific challenges and clinical perspectives. Advances in Biochemical Engineering/Biotechnology, 112. pp. 1-27.

Martin, Ivan and Smith, Timothy and Wendt, David. (2009) Bioreactor-based roadmap for the translation of tissue engineering strategies into clinical products. Trends in Biotechnology, 27 (9). pp. 495-502.

Wendt, David and Riboldi, Stefania A. and Cioffi, Margherita and Martin, Ivan. (2009) Potential and bottlenecks of bioreactors in 3D cell culture and tissue manufacturing. Advanced materials, Vol. 21. pp. 3352-3367.

Candrian, C. and Barbero, Andrea and Bonacina, E. and Francioli, S. and Hirschmann, M. T. and Milz, S. and Valderrabano, V. and Heberer, M. and Martin, I. and Jakob, M.. (2009) A novel implantation technique for engineered osteo-chondral grafts. Knee surgery, sports traumatology, arthroscopy : official journal of the European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA), Vol. 17. pp. 1377-1383.

Pelttari, Karoliina and Wixmerten, Anke and Martin, Ivan. (2009) Do we really need cartilage tissue engineering? Swiss medical weekly, Vol. 139, H. 41-42. pp. 602-609.

2008

Kon, Elizaveta and Chiari, Catharina and Marcacci, Maurilio and Delcogliano, Marco and Salter, Donald M. and Martin, Ivan and Ambrosio, Luigi and Fini, Milena and Tschon, Matilde and Tognana, Enrico and Plasenzotti, Roberto and Nehrer, Stefan. (2008) Tissue engineering for total meniscal substitution : Animal study in sheep model. Tissue engineering. Part A, Vol. 14, H. 6. pp. 1067-1080.

Degistirici, Ozer and Jaquiery, Claude and Schönebeck, Bodo and Siemonsmeier, Jürgen and Götz, Werner and Martin, Ivan and Thie, Michael. (2008) Defining properties of neural crest-derived progenitor cells from the apex of human developing tooth. Tissue engineering. Part A, Vol. 14, H. 2. pp. 317-330.

Cioffi, M. and Küffer, J. and Ströbel, S. and Dubini, G. and Martin, I. and Wendt, D.. (2008) Computational evaluation of oxygen and shear stress distributions in 3D perfusion culture systems : Macro-scale and micro-structured models. Journal Of Biomechanics, 41 (14). pp. 2918-2925.

Hoch, Matthias and Hirzel, Estelle and Lindinger, Peter and Eberle, Alex N. and Linscheid, Philippe and Martin, Ivan and Peters, Thomas and Peterli, Ralph. (2008) Weak Functional Coupling of the Melanocortin-1 Receptor Expressed in Human Adipocytes. Journal Of Receptors And Signal Transduction, Vol. 28, H. 5 , S. 485-504..

Candrian, C. and Vonwil, D. and Barbero, A. and Bonacina, E. and Miot, S. and Farhadi, J. and Wirz, D. and Dickinson, S. and Hollander, A. and Jakob, M. and Li, Z. and Alini, M. and Heberer, M. and Martin, I.. (2008) Engineered cartilage generated by nasal chondrocytes is responsive to physical forces resembling joint loading. Arthritis and rheumatism, 58 (1). pp. 197-208.

Barbero, A. and Candrian, C. and Bonacina, E. and Vonwil, D. and Farhadi, J. and Wirz, D. and Dickinson, S. and Jakob, M. and Alini, M. and Martin, I.. (2008) Engineered Cartilage generated by Nasal chondrocytes is responsive to physical forces resembling joint loading. Tissue engineering. Part A, Vol. 14, H. 5. p. 728.

Candrian, C. and Bonacina, E. and Frueh, J. and Dickinson, S. and Heberer, M. and Martin, I. and Barbero, A.. (2008) Intra-individual comparison of human ankle and knee chondrocytes in vitro : Relevance for talar cartilage repair. Tissue engineering. Part A, Vol. 14, H. 5. p. 750.

Scaglione, S. and Wendt, D. and Miggino, S. and Papadimitropoulos, A. and Fato, M. and Quarto, R. and Martin, I.. (2008) Effects of fluid flow and calcium phosphate coating on human bone marrow stromal cells cultured in a defined 2D model system. Journal of biomedical materials research. Part A, 86 (2). pp. 411-419.

Tampieri, Anna and Sandri, Monica and Landi, Elena and Pressato, Daniele and Francioli, Silvia and Quarto, Rodolfo and Martin, Ivan. (2008) Design of graded biomimetic osteochondral composite scaffolds. Biomaterials, 29 (26). pp. 3539-3546.

Wolf, F. and Haug, M. and Farhadi, J. and Candrian, C. and Martin, I. and Barbero, A.. (2008) A low percentage of autologous serum can replace bovine serum to engineer human nasal cartilage. European cells & materials, Vol. 15. pp. 1-10.

Feder-Mengus, C. and Ghosh, S. and Reschner, A. and Martin, I. and Spagnoli, G. C.. (2008) New dimensions in tumor immunology : what does 3D culture reveal? Trends in molecular medicine, 14 (8). pp. 333-340.

Kafienah, Wael and Cheung, Frank L. and Sims, Trevor and Martin, Ivan and Miot, Sylvie and Von Ruhland, Chris and Roughley, Peter J. and Hollander, Anthony P.. (2008) Lumican inhibits collagen deposition in tissue engineered cartilage. Matrix Biology, 27 (6). pp. 526-534.

Wolf, F. and Candrian, C. and Wendt, D. and Farhadi, J. and Heberer, M. and Martin, I. and Barbero, A.. (2008) Cartilage tissue engineering using pre-aggregated human articular chondrocytes. European cells & materials, Vol. 16. pp. 92-99.

Vonwil, D. and Wendt, D. and Stroebel, S. and Wallny, H. J. and Gygax, D. and Heberer, M. and Martin, I.. (2008) Assessment of the stability of TGFβ3 bioactivity for potential bioreactor applications. Biochemical Engineering Journal, 39 (3). pp. 586-589.

Schaeren, Stefan and Jaquiery, Claude and Heberer, Michael and Tolnay, Markus and Vercellotti, Tomaso and Martin, Ivan. (2008) Assessment of nerve damage using a novel ultrasonic device for bone cutting. Journal of oral and maxillofacial surgery, 66 (3). pp. 593-596.

Scheufler, Oliver and Schaefer, Dirk J. and Jaquiery, Claude and Braccini, Alessandra and Wendt, David J. and Gasser, Juerg A. and Galli, Raffaele and Pierer, Gerhard and Heberer, Michael and Martin, Ivan. (2008) Spatial and temporal patterns of bone formation in ectopically pre-fabricated, autologous cell-based engineered bone flaps in rabbits. Journal of cellular and molecular medicine, Vol. 12, no. 4. pp. 1238-1249.

Hoch, M. and Hirzel, E. and Lindinger, P. and Eberle, A. N. and Linscheid, P. and Martin, I. and Peters, T. and Peterli, R.. (2008) Weak functional coupling of the melanocortin-1 receptor expressed in human adipocytes. Journal of receptors and signal transduction, Vol. 28. pp. 485-504.

Vonwil, D. and Wendt, D. and Stroebel, S. and Wallny, H. J. and Gygax, D. and Heberer, M. and Martin, I.. (2008) Assessment of TGF-b3 bioactivity for potential bioreactor applications. Biochemical engineering journal, Vol. 39. pp. 586-589.

2007

Scherberich, Arnaud and Galli, Raffaele and Jaquiery, Claude and Farhadi, Jian and Martin, Ivan. (2007) Three-dimensional perfusion culture of human adipose tissue-derived endothelial and osteoblastic progenitors generates osteogenic constructs with intrinsic vascularization capacity. Stem Cells, 25 (7). pp. 1823-1829.

Ghosh, Sourabh and Josh, Manjunath B. and Ivanov, Danila and Feder-Mengus, Chantal and Spagnoli, Giulio C. and Martin, Ivan and Erne, Paul and Resink, Therese J.. (2007) Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: A role for T-cadherin in tumor angiogenesis. FEBS letters, Vol. 581, H. 23. pp. 4523-4528.

Francioli, Silvia-Elena and Martin, Ivan and Sie, Christina-Priska and Hagg, Rupert and Tommasini, Roberto and Candrian, Christian and Heberer, Michael and Barbero, Andrea. (2007) Growth factors for clinical-scale expansion of human articular chondrocytes : Relevance for automated bioreactor systems. Tissue engineering, Vol. 13, H. 6. pp. 1227-1234.

Timmins, Nicholas E. and Scherberich, Arnaud and Früh, Jennifer-Annika and Heberer, Michael and Martin, Ivan and Jakob, Marcel. (2007) Three-dimensional cell culture and tissue engineering in a T-CUP (tissue culture under perfusion). Tissue engineering, Vol. 13, H. 8. pp. 2021-2028.

Grogan, Shawn Patrick and Barbero, Andrea and Diaz-Romero, Jose and Cleton-Jansen, Anne-Marie and Soeder, Stephan and Whiteside, Robert and Hogendoorn, Pancras C. W. and Farhadi, Jian and Aigner, Thomas and Martin, Ivan and Mainil-Varlet, Pierre. (2007) Identification of markers to characterize and sort human articular chondrocytes with enhanced in vitro chondrogenic capacity. Arthritis and rheumatism, 56 (2). pp. 586-595.

Martin, Ivan and Miot, Sylvie and Barbero, Andrea and Jakob, Marcel and Wendt, David. (2007) Osteochondral tissue engineering. Journal Of Biomechanics, 40 (4). pp. 750-765.

Marsano, A. and Millward-Sadler, S. J. and Salter, D. M. and Adesida, A. and Hardingham, T. and Tognana, E. and Kon, E. and Chiari-Grisar, C. and Nehrer, S. and Jakob, M. and Martin, I.. (2007) Differential cartilaginous tissue formation by human synovial membrane, fat pad, meniscus cells and articular chondrocytes. Osteoarthritis And Cartilage, Vol. 15, H. 1. pp. 48-58.

Lipski, Anna Marie and Jaquiery, Claude and Choi, Hoon and Eberli, Daniel and Stevens, Molly and Martin, Ivan and Chen, I. -Wei and Shastri, Venkatram Prasad. (2007) Nanoscale engineering of biomaterial surfaces. Advanced materials, Vol. 19, no. 4. pp. 553-557.

Bocelli-Tyndall, C. and Bracci, L. and Spagnoli, G. and Braccini, A. and Bouchenaki, M. and Ceredig, R. and Pistoia, V. and Martin, I. and Tyndall, A.. (2007) Bone marrow mesenchymal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro. Rheumatology, 46 (3). pp. 403-408.

Feder-Mengus, C. and Ghosh, S. and Weber, W. P. and Wyler, S. and Zajac, P. and Terracciano, L. and Oertli, D. and Heberer, M. and Martin, I. and Spagnoli, G. C. and Reschner, A.. (2007) Multiple mechanisms underlie defective recognition of melanoma cells cultured in three-dimensional architectures by antigen-specific cytotoxic T lymphocytes. British journal of cancer, 96 (7). pp. 1072-1082.

2006

Laschke, Matthias W. and Harder, Yves and Amon, Michaela and Martin, Ivan and Farhadi, Jian and Ring, Andrej and Torio-Padron, Nestor and Schramm, Rene and Ruecker, Martin and Junker, Dominic and Haeufel, Joerg M. and Carvalho, Carlos and Heberer, Michael and Germann, Gunter and Vollmar, Brigitte and Menger, Michael D.. (2006) Angiogenesis in tissue engineering : Breathing life into constructed tissue substitutes. Tissue engineering, Vol. 12, H. 8. pp. 2093-2104.

Grogan, Shawn Patrick and Barbero, Andrea and Winkelmann, Verena and Rieser, Franz and Fitzsimmons, James S. and O`Driscoll, Shawn and Martin, Ivan and Mainil-Varlet, Pierre. (2006) Visual histological grading system for the evaluation of in vitro-generated neocartilage. Tissue Engineering, Vol. 12, H. 8. pp. 2141-2149.

Wendt, D. and Stroebel, S. and Jakob, M. and John, G. T. and Martin, I.. (2006) Uniform tissues engineered by seeding and culturing cells in 3D scaffolds under perfusion at defined oxygen tensions. Biorheology, Vol. 43, H. 3-4. pp. 481-488.

Farhadi, J. and Jaquiery, C. and Haug, M. and Pierer, G. and Zeilhofer, H. F. and Martin, I.. (2006) Bone and cartilage tissue engineering for facial reconstructive surgery. IEEE engineering in medicine and biology magazine, Vol. 25, 1. pp. 106-109.

Bocelli-Tyndall, Chiara and Barbero, Andrea and Candrian, Christian and Ceredig, Rhodri and Tyndall, Alan and Martin, Ivan. (2006) Human articular chondrocytes suppress in vitro proliferation of anti-CD3 activated peripheral blood mononuclear cells. Journal of cellular physiology, Vol. 209, no. 3. pp. 732-734.

Farhadi, Jian and Fulco, Ilario and Miot, Sylvie and Wirz, Dieter and Haug, Martin and Dickinson, Sally C. and Hollander, Anthony P. and Daniels, A. U. and Pierer, Gerhard and Heberer, Michael and Martin, Ivan. (2006) Precultivation of engineered human nasal cartilage enhances the mechanical properties relevant for use in facial reconstructive surgery. Annals of surgery, Vol. 244, Nr. 6. pp. 978-985.

Mahmood, Tahir A. and Miot, Sylvie and Frank, Oliver and Martin, Ivan and Riesle, Jens and Langer, Robert and van Blitterswijk, Clemens A.. (2006) Modulation of chondrocyte phenotype for tissue engineering by designing the biologic-polymer carrier interface. Biomacromolecules, 7. pp. 3012-3018.

Marsano, A. and Wendt, D. and Quinn, T. M. and Sims, T. J. and Farhadi, J. and Jakob, M. and Heberer, M. and Martin, I.. (2006) Bi-zonal cartilaginous tissues engineered in a rotary cell culture system. Biorheology, Vol. 43, H. 3-4. pp. 553-560.

Marsano, Anna and Wendt, David and Raiteri, Roberto and Gottardi, Riccardo and Stolz, Martin and Wirz, Dieter and Daniels, Alma U. and Salter, Donald and Jakob, Marcel and Quinn, Thomas M. and Martin, Ivan. (2006) Use of hydrodynamic forces to engineer cartilaginous tissues resembling the non-uniform structure and function of meniscus. Biomaterials, 27 (35). pp. 5927-5934.

Woodfield, T. B. F. and Miot, S. and Martin, I. and van Blitterswijk, C. A. and Riesle, J.. (2006) The regulation of expanded human nasal chondrocyte re-differentiation capacity by substrate composition and gas plasma surface modification. Biomaterials, 27 (7). pp. 1043-1053.

Barbero, Andrea and Grogan, Shawn Patrick and Mainil-Varlet, Pierre and Martin, Ivan. (2006) Expansion on specific substrates regulates the phenotype and differentiation capacity of human articular chondrocytes. Journal of Cellular Biochemistry, 2006. pp. 1140-1149.

Scaglione, S. and Braccini, A. and Wendt, D. and Jaquiery, C. and Beltrame, F. and Quarto, R. and Martin, I.. (2006) Engineering of osteoinductive grafts by isolation and expansion of ovine bone marrow stromal cells directly on 3D ceramic scaffolds. Biotechnology and bioengineering, 93 (1). pp. 181-187.

Nesic, Dobrila and Whiteside, Robert and Brittberg, Mats and Wendt, David and Martin, Ivan and Mainil-Varlet, Pierre. (2006) Cartilage tissue engineering for degenerative joint disease. Advanced drug delivery reviews, 58 (2). pp. 300-322.