Items where contributor is "Walker, Ulrich A."

2011

Aschwanden, Markus and Halter, Jörg P. and Walker, Ulrich A. and Staub, Daniel and Tichelli, André and Daikeler, Thomas and Jaeger, Kurt A. and Tyndall, Alan. (2011) Nail fold capillaroscopy differs widely between systemic sclerosis and chronic graft vs host disease of the skin. Rheumatology, Vol. 50, no. 6. pp. 1168-1169.

Galluccio, Felice and Walker, Ulrich A. and Nihtyanova, Svetlana and Moinzadeh, Pia and Hunzelmann, Nicholas and Krieg, Thomas and Steen, Virginia and Baron, Murray and Sampaio-Barros, Percival and Kayser, Cristiane and Nash, Peter and Denton, Chris P. and Tyndall, Alan and Müller-Ladner, Ulf and Matucci-Cerinic, Marco. (2011) Registries in systemic sclerosis : a worldwide experience. Rheumatology, Vol. 50, no. 1. pp. 60-68.

Walker, and Ulrich, A. and Courvoisier, and Delphine, S. and Dudler, and Jean, and Aeberli, and Daniel, and von Kempis, and Johannes, and Scherer, and Almut, and Finckh, and Axel, and Swiss, Clinical Quality Management Programme in Rheumatic Diseases. (2011) Do new biologics meet the unmet medical need in rheumatoid arthritis? : safety and efficacy of abatacept following B-cell depletion. Rheumatology, Vol. 50, no. 1. pp. 243-244.

Beyer, Christian and Distler, Jörg H. W. and Allanore, Yannick and Aringer, Martin and Avouac, Jérôme and Czirják, László and Cutolo, Maurizio and Damjanov, Nemanja and Del Galdo, Francesco and Fligelstone, Kim and Guiducci, Serena and Kowal-Bielecka, Otylia and van Laar, Jacob M. and Martucci-Cerinic, Marco and Müller-Ladner, Ulf and Riemekasten, Gabriela and Tarner, Ingo H. and Tyndall, Alan and Kennedy, Ann Tyrrell and Valentini, Gabriele and Vettori, Serena and Walker, Ulrich A. and Denton, Christopher and Distler, Oliver and Eustar Biobanking Group, . (2011) EUSTAR biobanking : recommendations for the collection, storage and distribution of biospecimens in scleroderma research. Annals of the rheumatic diseases, Vol. 70, H. 7. pp. 1178-1182.

Aschwanden, Markus and Jaeger, Kurt and Benz, Daniela and Tyndall, Alan and Walker, Ulrich A.. (2011) Clinical images: calcinosis and capillaries. Arthritis & rheumatism, Vol. 63, H. 1. p. 179.

Avouac, J. and Fransen, J. and Walker, U. A. and Riccieri, V. and Smith, V. and Muller, C. and Miniati, I. and Tarner, I. H. and Randone, S. Bellando and Cutolo, M. and Allanore, Y. and Distler, O. and Valentini, G. and Czirjak, L. and Müller-Ladner, U. and Furst, D. E. and Tyndall, A. and Matucci-Cerinic, M. and Eustar Group, . (2011) Preliminary criteria for the very early diagnosis of systemic sclerosis : results of a Delphi Consensus Study from EULAR Scleroderma Trials and Research Group. Annals of the rheumatic diseases, Vol. 70, H. 3. pp. 476-481.

Pöllinger, Bernadette and Junt, Tobias and Metzler, Barbara and Walker, Ulrich A. and Tyndall, Alan and Allard, Cyril and Bay, Serkan and Keller, Roland and Raulf, Friedrich and Di Padova, Franco and O'Reilly, Terrence and Horwood, Nicole J. and Patel, Dhavalkumar D. and Littlewood-Evans, Amanda. (2011) Th17 cells, not IL-17+ ?? T cells, drive arthritic bone destruction in mice and humans. Journal of immunology, Vol. 186, H. 4. pp. 2602-2612.

Hügle, Thomas and Schuetz, Philipp and Daikeler, Thomas and Tyndall, Alan and Matucci-Cerinic, Marco and Walker, Ulrich A. and van Laar, Jacob M. and Eustar members, . (2011) Late-onset systemic sclerosis--a systematic survey of the EULAR scleroderma trials and research group database. Rheumatology, Vol. 50, no. 1. pp. 161-165.

Koligi, K. and Mertz, D. and Benz, D. and Vogt, T. and Bloemberg, G. V. and Winter, L. and Tyndall, A. and Battegay, M. and Walker, U. A.. (2011) [Of bugs and joints. Oligoarthritis caused by Tropheryma whipplei]. Der Internist, Vol. 52, no. 7. pp. 884-888.

Côté, Hélène C. F. and Gerschenson, Mariana and Walker, Ulrich A. and Miro, Oscar and Garrabou, Gloria and Hammond, Emma and Villarroya, Joan and Giralt, Marta and Villarroya, Francesc and Cinque, Paola and Garcia-Arumi, Elena and Andreu, Antonio L. and Pinti, Marcello and Cossarizza, Andrea. (2011) Quality assessment of human mitochondrial DNA quantification : MITONAUTS, an international multicentre survey. Mitochondrion, Vol. 11, H. 3. pp. 520-527.

Weinberg, Melissa E. and Roman, Mark C. and Jacob, Peyton and Wen, Michael and Cheung, Polly and Walker, Ulrich A. and Mulligan, Kathleen and Schambelan, Morris. (2011) Enhanced uridine bioavailability following administration of a triacetyluridine-rich nutritional supplement. PLoS one, Vol. 6, H. 2 , e14709.

Sevastianova, Ksenia and Sutinen, Jussi and Greco, Dario and Sievers, Meline and Salmenkivi, Kaisa and Perttilä, Julia and Olkkonen, Vesa M. and Wågsäter, Dick and Lidell, Martin E. and Enerbäck, Sven and Eriksson, Per and Walker, Ulrich A. and Auvinen, Petri and Ristola, Matti and Yki-Järvinen, Hannele. (2011) Comparison of dorsocervical with abdominal subcutaneous adipose tissue in patients with and without antiretroviral therapy-associated lipodystrophy. Diabetes, Vol. 60, H. 7. pp. 1894-1900.

2010

Aschwanden, Markus and Kesten, Friederike and Stern, Martin and Thalhammer, Christoph and Walker, Ulrich A. and Tyndall, Alan and Jaeger, Kurt A. and Hess, Christoph and Daikeler, Thomas. (2010) Vascular involvement in patients with giant cell arteritis determined by duplex sonography of 2x11 arterial regions. Annals of the rheumatic diseases, Vol. 69, H. 7. pp. 1356-1359.

Avouac, Jerome and Walker, Ulrich and Tyndall, Alan and Kahan, André and Matucci-Cerinic, Marco and Allanore, Yannick and Eustar, and Miniati, I. and Muller, A. and Iannone, F. and Distler, O. and Becvar, R. and Sierakowsky, S. and Kowal-Bielecka, O. and Coelho, P. and Cabane, J. and Cutolo, M. and Shoenfeld, Y. and Valentini, G. and Rovensky, J. and Riemekasten, G. and Vlachoyiannopoulos, P. and Caporali, R. and Jiri, S. and Inanc, M. and Zimmermann Gorska, I. and Carreira, P. and Novak, S. and Czirjak, L. and Oliveira Ramos, F. and Jendro, M. and Chizzolini, C. and Kucharz, E. J. and Richter, J. and Cozzi, F. and Rozman, B. and Mallia, C. M. and Gabrielli, A. and Farge, D. and Kiener, H. P. and Schöffel, D. and Airo, P. and Wollheim, F. and Martinovic, D. and Trotta, F. and Jablonska, S. and Reich, K. and Bombardieri, S. and Siakka, P. and Pellerito, R. and Bambara, L. M. and Morovic-Vergles, J. and Denton, C. and Hinrichs, R. and Van den Hoogen, F. and Damjanov, N. and Kötter, I. and Ortiz, V. and Heitmann, S. and Krasowska, D. and Seidel, M. and Hasler, P. and Van Laar, J. M. and Kaltwasser, J. P. and Foeldvari, I. and Juan Mas, A. and Bajocchi, G. and Wislowska, M. and Pereira Da Silva, J. A. and Jacobsen, S. and Worm, M. and Graniger, W. and Kuhn, A. and Stankovic, A. and Cossutta, R. and Majdan, M. and Damjanovska Rajcevska, L. and Tikly, M. and Nasonov, E. L. and Steinbrink, K. and Herrick, A. and Müller-Ladner, U. and Dinc, A. and Scorza, R. and Sondergaard, K. and Indiveri, F. and Nielsen, H. and Szekanecz, Z. and Silver, R. M. and Antivalle, M. and Espinosa, I. B. and García de la Pena Lefebvre, P. and Midtvedt, O. and Launay, D. and Valesini, F. and Tuvik, P. and Ionescu, R. M. and Del Papa, N. and Pinto, S. and Wigley, F. and Mihai, C. and Sinziana Capranu, M. and Sunderkötter, C. and Jun, J. B. and Alhasani, S. and Distler, J. H. and Ton, E. and Soukup, T. and Seibold, J. and Zeni, S. and Nash, P. and Mouthon, L. and De Keyser, F. and Duruöz, M. T. and Cantatore, F. P. and Strauss, G. and von Mülhen, C. A. and Pozzi, M. R. and Eyerich, K. and Szechinski, J. and Keiserman, M. and Houssiau, F. A. and Román-Ivorra, J. A. and Krummel-Lorenz, B. and Aringer, M. and Westhovens, R. and Bellisai, F. and Mayer, M. and Stoeckl, F. and Uprus, M. and Volpe, A. and Buslau, M. and Yavuz, S. and Granel, B. and Valderílio Feijó, A. and Del Galdo, F. and Popa, S. and Zenone, T. and Ricardo Machado, X. and Pileckyte, M. and Stebbings, S. and Mathieu, A. and Tulli, A. and Tourinho, T. and Souza, R. and Acayaba de Toledo, R. and Stamp, L. and Solanki, K. and Veale, D. and Francisco Marques Neto, J. and Bagnato, G. F. and Loyo, E. and Toloza, S. and Li, M. and Ahmed Abdel Atty Mohamed, W. and Cobankara, V. and Olas, J. and Salsano, F. and Oksel, F. and Tanaseanu, C. M. and Foti, R. and Ancuta, C. and Vonk, M. and Caramashi, P. and Beretta, L. and Balbir, A. and Chiàla, A. and Pasalic Simic, K. and Ghio, M. and Stamenkovic, B. and Rednic, S. and Host, N. and Pellerito, R. and Hachulla, E. and Furst, D. E.. (2010) Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database. The journal of rheumatology, Vol. 37, H. 7. pp. 1488-1501.

Finckh, A. and Ciurea, A. and Brulhart, L. and Möller, B. and Walker, U. A. and Courvoisier, D. and Kyburz, D. and Dudler, J. and Gabay, C. and Arthritis, . (2010) Which subgroup of patients with rheumatoid arthritis benefits from switching to rituximab versus alternative anti-tumour necrosis factor (TNF) agents after previous failure of an anti-TNF agent? Annals of the rheumatic diseases, Vol. 69, H. 2. pp. 387-393.

McComsey Grace, A. and Walker, Ulrich A. and Budhathoki Chakra, B. and Su, Zhaohui and Currier, Judith S. and Kosmiski, Lisa and Naini, Linda G. and Charles, Stéphannie and Medvik, Kathy and Aberg, Judith A.. (2010) Uridine supplementation in the treatment of HIV lipoatrophy : results of ACTG 5229. AIDS, Vol. 24, H. 6. pp. 2507-2515.

Dudler, Jean and Finckh, Axel and Kyburz, Diego and Langenegger, Thomas and Möller, Burkhard and Schmiedel, Ute and Walker, Ulrich A.. (2010) Swiss consensus statement: Recommendations for optimising re-treatment with MabThera (rituximab) in rheumatoid arthritis. Rheumatology, Vol. 140 , w13073.

Effelsberg, Nora M. and Hügle, Thomas and Walker, Ulrich A.. (2010) A metabolic cause of spinal deformity. Metabolism, Vol. 59, H. 1. pp. 140-143.

Balcarek, Kerstin and Venhoff, Nils and Deveaud, Catherine and Beauvoit, Bertrand and Bonnet, Jacques and Kirschner, Janbernd and Venhoff, Ana C. and Lebrecht, Dirk and Walker, Ulrich A.. (2010) Role of pyrimidine depletion in the mitochondrial cardiotoxicity of nucleoside analogue reverse transcriptase inhibitors. JAIDS: journal of acquired immune deficiency syndromes, Vol. 55, H. 5. pp. 550-557.

Venhoff, Nils and Lebrecht, Dirk and Deveaud, Catherine and Beauvoit, Bertrand and Bonnet, Jacques and Müller, Klaus and Kirschner, Janbernd and Venhoff, Ana C. and Walker, Ulrich A.. (2010) Oral uridine supplementation antagonizes the peripheral neuropathy and encephalopathy induced by antiretroviral nucleoside analogues. AIDS, Vol. 24, H. 3. pp. 345-352.

Allanore, Y. and Meune, C. and Vonk, M. C. and Airo, P. and Hachulla, E. and Caramaschi, P. and Riemekasten, G. and Cozzi, F. and Beretta, L. and Derk, C. T. and Komócsi, A. and Farge, D. and Balbir, A. and Riccieri, V. and Distler, O. and Chialà, A. and Papa, N. Del and Simic, K. Pasalic and Ghio, M. and Stamenkovic, B. and Rednic, S. and Host, N. and Pellerito, R. and Zegers, E. and Kahan, A. and Walker, U. A. and Matucci-Cerinic, M. and Eustar co-authors, . (2010) Prevalence and factors associated with left ventricular dysfunction in the EULAR Scleroderma Trial and Research group (EUSTAR) database of patients with systemic sclerosis. Annals of the rheumatic diseases, Vol. 69, H. 1. pp. 218-221.

Tyndall, Anthony J. and Bannert, Bettina and Vonk, Madelon and Airò, Paolo and Cozzi, Franco and Carreira, Patricia E. and Bancel, Dominique Farge and Allanore, Yannick and Müller-Ladner, Ulf and Distler, Oliver and Iannone, Florenzo and Pellerito, Raffaele and Pileckyte, Margarita and Miniati, Irene and Ananieva, Lidia and Gurman, Alexandra Balbir and Damjanov, Nemanja and Mueller, Adelheid and Valentini, Gabriele and Riemekasten, Gabriela and Tikly, Mohammed and Hummers, Laura and Henriques, Maria J. S. and Caramaschi, Paola and Scheja, Agneta and Rozman, Blaz and Ton, Evelien and Kumánovics, Gábor and Coleiro, Bernard and Feierl, Eva and Szucs, Gabriella and Von Mühlen, Carlos Alberto and Riccieri, Valeria and Novak, Srdan and Chizzolini, Carlo and Kotulska, Anna and Denton, Christopher and Coelho, Paulo C. and Kötter, Ina and Simsek, Ismail and de la Pena Lefebvre, Paloma García and Hachulla, Eric and Seibold, James R. and Rednic, Simona and Stork, Jirí and Morovic-Vergles, Jadranka and Walker, Ulrich A.. (2010) Causes and risk factors for death in systemic sclerosis : a study from the EULAR Scleroderma Trials and Research (EUSTAR) database. Annals of the rheumatic diseases, Vol. 69, H. 10. pp. 1809-1815.

Rizzi, Marta and Knoth, Rolf and Hampe, Christiane S. and Lorenz, Peter and Gougeon, Marie-Lise and Lemercier, Brigitte and Venhoff, Nils and Ferrera, Francesca and Salzer, Ulrich and Thiesen, Hans-Jürgen and Peter, Hans-Hartmut and Walker, Ulrich A. and Eibel, Hermann. (2010) Long-lived plasma cells and memory B cells produce pathogenic anti-GAD65 autoantibodies in Stiff Person Syndrome. PLoS one, Vol. 5, H. 5 , e10838.

Lebrecht, Dirk and Kirschner, Janbernd and Geist, Andrea and Haberstroh, Jörg and Walker, Ulrich A.. (2010) Respiratory chain deficiency precedes the disrupted calcium homeostasis in chronic doxorubicin cardiomyopathy. Cardiovascular pathology, Vol. 19, H. 5 , e167-174.

Sutinen, Jussi and Laaksonen, Marko S. and Walker, Ulrich A. and Setzer, Bernhard and Kemppainen, Jukka and Nuutila, Pirjo and Yki-Järvinen, Hannele. (2010) Skeletal muscle mitochondrial DNA content and aerobic metabolism in patients with antiretroviral therapy-associated lipoatrophy. Journal of Antimicrobial Chemotherapy, Vol. 65, H. 7. pp. 1497-1504.

2009

Distler, J. H. and Allanore, Y. and Avouac, J. and Giacomelli, R. and Guiducci, S. and Moritz, F. and Akhmetshina, A. and Walker, U. A. and Gabrielli, A. and Müller-Ladner, U. and Tyndall, A. and Matucci-Cerinic, M. and Distler, O. and Eular, Scleroderma Trials and Research, group. (2009) EULAR Scleroderma Trials and Research group statement and recommendations on endothelial precursor cells. Annals of the rheumatic diseases : ARD, Vol. 68. pp. 163-168.

Hügle, T. and Gratzl, S. and Daikeler, T. and Frey, D. and Tyndall, A. and Walker, U. A.. (2009) Sclerosing skin disorders in association with multiple sclerosis. Coincidence, underlying autoimmune pathology or interferon induced? Annals of the rheumatic diseases : ARD, Vol. 68. pp. 47-50.

Walker, U. A. and Tyndall, A. and Czirják, L. and Denton, C. P. and Farge-Bancel, D. and Kowal-Bielecka, O. and Müller-Ladner, U. and Matucci-Cerinic, M.. (2009) Geographical variation of disease manifestations in systemic sclerosis : a report from the EULAR Scleroderma Trials and Research (EUSTAR) group database. Annals of the rheumatic diseases : ARD, Vol. 68. pp. 856-862.

Sievers, M. and Walker, U. A. and Sevastianova, K. and Setzer, B. and Wågsäter, D. and Eriksson, P. and Yki-Järvinen, H. and Sutinen, J.. (2009) Gene expression and immunohistochemistry in adipose tissue of HIV type 1-infected patients with nucleoside analogue reverse-transcriptase inhibitor-associated lipoatrophy. The Journal of Infectious Diseases, Vol. 200. pp. 252-262.

Gingelmaier, Andrea and Grubert, Thomas A. and Kost, Bernd P. and Setzer, Bernhard and Lebrecht, Dirk and Mylonas, Ioannis and Mueller-Hoecker, Josef and Jeschke, Udo and Hiedl, Stephan and Friese, Klaus and Walker, Ulrich A.. (2009) Mitochondrial toxicity in HIV type-1-exposed pregnancies in the era of highly active antiretroviral therapy. Antiviral therapy : an official publication of the International Society for Antiviral Research, Vol. 14. pp. 331-338.

Venhoff, Ana C. and Lebrecht, Dirk and Reuss, Frank U. and Heckl-Ostreicher, Brigitte and Wehr, Roland and Walker, Ulrich A. and Venhoff, Nils. (2009) Mitochondrial DNA depletion in rat liver induced by fosalvudine tidoxil, a novel nucleoside reverse transcriptase inhibitor prodrug. Antimicrobial agents and chemotherapy : AAC, Vol. 53. pp. 2748-2751.

Kremer, H. and Sonnenberg-Schwan, U. and Arendt, G. and Brockmeyer, N. H. and Potthoff, A. and Ulmer, A. and Graefe, K. and Lorenzen, T. and Starke, W. and Walker, U. A. and German Competence Network HIV/Aids, . (2009) HIV or HIV-therapy? Causal attributions of symptoms and their impact on treatment decisions among women and men with HIV. European journal of medical research : official organ "Deutsche AIDS-Gesellschaft", Vol. 14. pp. 139-146.

Lebrecht, Dirk and Venhoff, Ana C. and Kirschner, Janbernd and Wiech, Thorsten and Venhoff, Nils and Walker, Ulrich A.. (2009) Mitochondrial tubulopathy in tenofovir disoproxil fumarate-treated rats. JAIDS : journal of acquired immune deficiency syndromes : official publication of the International Retrovirology Association, Vol. 51. pp. 258-263.

Spoerl, David and Bär, Diego and Cooper, Julian and Vogt, Thomas and Tyndall, Alan and Walker, Ulrich A.. (2009) Multisegmental spondylitis due to Tropheryma whipplei : case report. Orphanet journal of rare diseases : OJRD, Vol. 4. p. 13.

Wanner, D. P. and Tyndall, A. and Walker, U. A.. (2009) Tenofovir-induced osteomalacia. Clinical and experimental rheumatology : an international journal of rheumatic and connective tissue diseases, Vol. 27. pp. 1001-1003.

Walker, U. A. and Tyndall, A. and Ruszat, R.. (2009) Erectile dysfunction in systemic sclerosis. Annals of the rheumatic diseases, Vol. 68, H. 7. pp. 1083-1085.

Walker, . (2009) More about masitinib. Arthritis research & therapy, Vol. 11, H. 4. p. 120.

Venhoff, N. and Rizzi, M. and Salzer, U. and Bossaller, L. and Thoden, J. and Eibel, H. and Walker, U. A.. (2009) Monozygotic twins with stiff person syndrome and autoimmune thyroiditis : rituximab inefficacy in a double-blind, randomised, placebo controlled crossover study. Annals of the rheumatic diseases, Vol. 68, H. 9. pp. 1506-1508.

Walker, U. A. and Knöss, P. and Jakobs, M. and Krenn, V.. (2009) [Scleroderma and fibrosing diseases]. Zeitschrift für Rheumatologie, Vol. 68. pp. 312-319.

2008

McComsey, G. A. and Lo Re, V. and O'Riordan, M. and Walker, U. A. and Lebrecht, D. and Baron, E. and Mounzer, K. and Frank, I.. (2008) Effect of reducing the dose of stavudine on body composition, bone density, and markers of mitochondrial toxicity in HIV-infected subjects: a randomized, controlled study. Clinical infectious diseases, Vol. 46. pp. 1290-1296.

Setzer, B. and Lebrecht, D. and Walker, U. A.. (2008) Pyrimidine nucleoside depletion sensitizes to the mitochondrial hepatotoxicity of the reverse transcriptase inhibitor stavudine. American Journal of Pathology, Vol. 172, no. 3. pp. 681-690.

McComsey, G. A. and O'Riordan, M. and Setzer, B. and Lebrecht, D. and Baron, E. and Walker, U. A.. (2008) Uridine supplementation in HIV lipoatrophy : pilot trial on safety and effect on mitochondrial indices. European journal of clinical nutrition : EJCN, Vol. 62. pp. 1031-1037.

McComsey, Grace A. and Kang, Minhee and Ross, Allison C. and Lebrecht, Dirk and Livingston, Elizabeth and Melvin, Ann and Hitti, Jane and Cohn, Susan E. and Walker, Ulrich A.. (2008) Increased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapy. HIV clinical trials, Vol. 9, H. 2. pp. 126-136.

Lebrecht, D. and Deveaud, C. and Beauvoit, B. and Bonnet, J. and Kirschner, J. and Walker, U. A.. (2008) Uridine supplementation antagonizes zidovudine-induced mitochondrial myopathy and hyperlactatemia in mice. Arthritis & rheumatism, Vol. 58, H. 1. pp. 318-326.

Walker, U. A. and Tyndall, A. and Daikeler, T.. (2008) Rheumatic conditions in human immunodeficiency virus infection. Rheumatology, Vol. 47, no. 7. pp. 952-959.

Walker, Ulrich A. and Hasler, Paul. (2008) [Safety and efficacy of biologics directed against TNF-alpha and CD20 in the therapy of vasculitis and systemic lupus erythematosus]. Therapeutische Umschau, Vol. 65, H. 5. pp. 303-310.

Venhoff, N. and Venhoff, A. C. and Jayewardene, A. L. and Aweeka, F. and Lebrecht, D. and Walker, U. A.. (2008) Pharmacokinetics of zidovudine and lamivudine during oral uridine supplementation with NucleomaxX. JAIDS: journal of acquired immune deficiency syndromes, Vol. 48, H. 1. pp. 114-116.

Thoden, J. and Lebrecht, D. and Venhoff, N. and Neumann, J. and Müller, K. and Walker, U. A.. (2008) Highly active antiretroviral HIV therapy-associated fatal lactic acidosis : quantitative and qualitative mitochondrial DNA lesions with mitochondrial dysfunction in multiple organs. AIDS, Vol. 22, H. 9. pp. 1093-1094.