Browse by Basel Contributors ID
2017Singer, Jochen and Ruscheweyh, Hans-Joachim and Hofmann, Ariane L. and Thurnherr, Thomas and Singer, Franziska and Toussaint, Nora C. and Ng, Charlotte K. Y. and Piscuoglio, Salvatore and Beisel, Christian and Christofori, Gerhard and Dummer, Reinhard and Hall, Michael N. and Krek, Wilhelm and Levesque, Mitchell and Manz, Markus G. and Moch, Holger and Papassotiropoulos, Andreas and Stekhoven, Daniel J. and Wild, Peter and Wüst, Thomas and Rinn, Bernd and Beerenwinkel, Niko. (2017) NGS-pipe: a flexible, easily extendable, and highly configurable framework for NGS analysis. Bioinformatics . pp. 1-2. Fitter, Stephen and Matthews, Mary P. and Martin, Sally K. and Xie, Jianling and Ooi, Soo Siang and Walkley, Carl R. and Codrington, John D. and Ruegg, Markus A. and Hall, Michael N. and Proud, Christopher G. and Gronthos, Stan and Zannettino, Andrew C. W.. (2017) mTORC1 Plays an Important Role in Skeletal Development by Controlling pre-Osteoblast Differentiation. Molecular and Cellular Biology, 37 (7). e00668-16. González, Asier and Hall, Michael N.. (2017) Nutrient sensing and TOR signaling in yeast and mammals. The EMBO Journal, 36 (4). pp. 397-408. Benjamin, Don and Hall, Michael N.. (2017) mTORC1 Controls Synthesis of Its Activator GTP. Cell Reports , 19 (13). pp. 2643-2644. Blandino-Rosano, Manuel and Barbaresso, Rebecca and Jimenez-Palomares, Margarita and Bozadjieva, Nadejda and Werneck-de-Castro, Joao Pedro and Hatanaka, Masayuki and Mirmira, Raghavendra G. and Sonenberg, Nahum and Liu, Ming and Rüegg, Markus A. and Hall, Michael N. and Bernal-Mizrachi, Ernesto. (2017) Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing. Nature Communications, 8. p. 16014. Bozadjieva, Nadejda and Blandino-Rosano, Manuel and Chase, Jennifer and Dai, Xiao-Qing and Cummings, Kelsey and Gimeno, Jennifer and Dean, Danielle and Powers, Alvin C. and Gittes, George K. and Rüegg, Markus A. and Hall, Michael N. and MacDonald, Patrick E. and Bernal-Mizrachi, Ernesto. (2017) Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion. Journal of Clinical Investigation. pp. 1-15. Tang, Fei and Zhang, Peng and Ye, Peiying and Lazarski, Christopher A. and Wu, Qi and Bergin, Ingrid L. and Bender, Timothy P. and Hall, Michael N. and Cui, Ya and Zhang, Liguo and Jiang, Taijiao and Liu, Yang and Zheng, Pan. (2017) A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice. eLife, 6. aheadofrint. Hall, Michael N.. (2017) An Amazing Turn of Events. Cell, 171 (1). pp. 18-22. Guri, Yakir and Colombi, Marco and Dazert, Eva and Hindupur, Sravanth K. and Roszik, Jason and Moes, Suzette and Jenoe, Paul and Heim, Markus H. and Riezman, Isabelle and Riezman, Howard and Hall, Michael N.. (2017) mTORC2 Promotes Tumorigenesis via Lipid Synthesis. Cancer Cell, 32 (6). pp. 807-832. 2016Swierczynska, Marta M. and Hall, Michael N.. (2016) eIF4A moonlights as an off switch for TORC1. The EMBO Journal, 35 (10). pp. 1013-1014. Grahammer, Florian and Nesterov, Viatcheslav and Ahmed, Azaz and Steinhardt, Frederic and Sandner, Lukas and Arnold, Frederic and Cordts, Tomke and Negrea, Silvio and Bertog, Marko and Ruegg, Marcus A. and Hall, Michael N. and Walz, Gerd and Korbmacher, Christoph and Artunc, Ferruh and Huber, Tobias B.. (2016) mTORC2 critically regulates renal potassium handling. Journal of Clinical Investigation, 126 (5). pp. 1773-1782. Drägert, Katja and Bhattacharya, Indranil and Hall, Michael N. and Humar, Rok and Battegay, Edouard and Haas, Elvira. (2016) Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue. Biochemical and Biophysical Research Communications, 473 (1). pp. 317-322. Zhang, Lianjun and Tschumi, Benjamin O. and Lopez-Mejia, Isabel C. and Oberle, Susanne G. and Meyer, Marten and Samson, Guerric and Rüegg, Markus A. and Hall, Michael N. and Fajas, Lluis and Zehn, Dietmar and Mach, Jean-Pierre and Donda, Alena and Romero, Pedro. (2016) Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner. Cell Reports , 14 (5). pp. 1206-1217. Dazert, Eva and Colombi, Marco and Boldanova, Tujana and Moes, Suzette and Adametz, David and Quagliata, Luca and Roth, Volker and Terracciano, Luigi and Heim, Markus H. and Jenoe, Paul and Hall, Michael N.. (2016) Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patient. Proceedings of the National Academy of Sciences of the United States of America, 113 (5). pp. 1381-1386. Aylett, Christopher H. S. and Sauer, Evelyn and Imseng, Stefan and Boehringer, Daniel and Hall, Michael N. and Ban, Nenad and Maier, Timm. (2016) Architecture of human mTOR complex 1. Science, 351 (6268). pp. 48-52. Shimobayashi, Mitsugu and Hall, Michael N.. (2016) Multiple amino acid sensing inputs to mTORC1. Cell research, 26 (1). pp. 7-20. Shende, Pankaj and Xu, Lifen and Morandi, Christian and Pentassuglia, Laura and Heim, Philippe and Lebboukh, Sonia and Berthonneche, Corinne and Pedrazzini, Thierry and Kaufmann, Beat A. and Hall, Michael N. and Rüegg, Markus A. and Brink, Marijke. (2016) Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy. Cardiovascular Research, 109 (1). pp. 103-114. Albert, Verena and Svensson, Kristoffer and Shimobayashi, Mitsugu and Colombi, Marco and Muñoz, Sergio and Jimenez, Veronica and Handschin, Christoph and Bosch, Fatima and Hall, Michael N.. (2016) mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Molecular Medicine, 8 (3). pp. 232-246. Fonseca, Bruno D. and Graber, Tyson E. and Hoang, Huy-Dung and González, Asier and Soukas, Alexandre A. and Hernández, Greco and Alain, Tommy and Swift, Stephanie L. and Weisman, Ronit and Meyer, Christian and Robaglia, Christophe and Avruch, Joseph and Hall, Michael N.. (2016) Evolution of TOR and Translation Control. In: Evolution of the Protein Synthesis Machinery and Its Regulation. Cham, pp. 327-412. Hall, Michael N.. (2016) TOR and paradigm change: cell growth is controlled. Molecular Biology of the Cell, 27 (18). pp. 2804-2806. Driscoll, David R. and Karim, Saadia A. and Sano, Makoto and Gay, David M. and Jacob, Wright and Yu, Jun and Mizukami, Yusuke and Gopinathan, Aarthi and Jodrell, Duncan I. and Evans, T. R. Jeffry and Bardeesy, Nabeel and Hall, Michael N. and Quattrochi, Brian J. and Klimstra, David S. and Barry, Simon T. and Sansom, Owen J. and Lewis, Brian C. and Morton, Jennifer P.. (2016) mTORC2 signaling drives the development and progression of pancreatic cancer. Cancer Research, 76 (23). pp. 6911-6923. Ding, Xiaolei and Bloch, Wilhelm and Iden, Sandra and Rüegg, Markus A. and Hall, Michael N. and Leptin, Maria and Partridge, Linda and Eming, Sabine A.. (2016) mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nature Communications, 7. p. 13226. Herkert, Barbara and Kauffmann, Audrey and Mollé, Sandra and Schnell, Christian and Ferrat, Thomas and Voshol, Hans and Juengert, Janina and Erasimus, Hélène and Marszalek, Grégory and Kazic-Legueux, Malika and Billy, Eric and Ruddy, David and Stump, Mark and Guthy, Daniel and Ristov, Mitko and Calkins, Keith and Maira, Sauveur-Michel and Sellers, William R. and Hofmann, Francesco and Hall, Michael N. and Brachmann, Saskia M.. (2016) Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition. Cancer Research, 76 (2). pp. 390-402. Swierczynska, Marta M. and Hall, Michael N.. (2016) mTOR in Metabolic and Endocrine Disorders. In: Molecules to Medicine with mTOR. Translating Critical Pathways into Novel Therapeutic Strategies. London, pp. 347-364. Guri, Yakir and Hall, Michael N.. (2016) mTOR Signaling Confers Resistance to Targeted Cancer Drugs. Trends in Cancer, 2 (11). pp. 688-697. Benjamin, Don and Colombi, Marco and Hindupur, Sravanth K. and Betz, Charles and Lane, Heidi A. and El-Shemerly, Mahmoud Y. M. and Lu, Min and Quagliata, Luca and Terracciano, Luigi and Moes, Suzette and Sharpe, Timothy and Wodnar-Filipowicz, Aleksandra and Moroni, Christoph and Hall, Michael N.. (2016) Syrosingopine sensitizes cancer cells to killing by metformin. Science Advances, 2 (12). e1601756. 2015Aimi, Fabio and Georgiopoulou, Stavroula and Kalus, Ina and Lehner, Fabienne and Hegglin, Alica and Limani, Përparim and Gomes de Lima, Vinicius and Rüegg, Markus A. and Hall, Michael N. and Lindenblatt, Nicole and Haas, Elvira and Battegay, Edouard J. and Humar, Rok. (2015) Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult. Scientific Reports, 5. p. 17705. Liko, Dritan and Hall, Michael N.. (2015) mTOR in health and in sickness. Journal of Molecular Medicine, 93 (10). pp. 1061-1073. Faller, W. J. and Jackson, T. J. and Knight, J. R. P. and Ridgway, R. A. and Jamieson, T. and Karim, S. A. and Jones, C. and Radulescu, S. and Huels, D. J. and Myant, K. B. and Dudek, K. M. and Casey, H. A. and Scopelliti, A. and Cordero, J. B. and Vidal, M. and Pende, M. and Ryazanov, A. G. and Sonenberg, N. and Meyuhas, O. and Hall, M. N. and Bushell, M. and Willis, A. E. and Sansom, O. J.. (2015) mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature, 517 (7535). pp. 497-500. González, A. and Shimobayashi, M. and Eisenberg, T. and Merle, D. A. and Pendl, T. and Hall, M. N. and Moustafa, T.. (2015) TORC1 Promotes Phosphorylation of Ribosomal Protein S6 via the AGC Kinase Ypk3 in Saccharomyces cerevisiae. PLoS one, Vol. 10, H. 3 , e0120250. Lopez, Rubén J. and Mosca, Barbara and Treves, Susan and Maj, Marcin and Bergamelli, Leda and Calderon, Juan C. and Bentzinger, C. Florian and Romanino, Klaas and Hall, Michael N. and Rüegg, Markus A. and Delbono, Osvaldo and Caputo, Carlo and Zorzato, Francesco. (2015) Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex. Biochemical Journal, 466 (1). pp. 123-135. Martin, S. K. and Fitter, S. and Dutta, A. K. and Matthews, M. P. and Walkley, C. R. and Hall, M. N. and Ruegg, M. A. and Gronthos, S. and Zannettino, A. C. W.. (2015) The differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation. Stem cells, Vol. 33, H. 4. pp. 1359-1365. Venkatesh, A. and Ma, S. and Le, Y. Z. and Hall, M. N. and Rüegg, M. A. and Punzo, C.. (2015) Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. Journal of Clinical Investigation, 125 (4). pp. 1446-1458. Carr, T. D. and Feehan, R. P. and Hall, M. N. and Rüegg, M. A. and Shantz, L. M.. (2015) Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. Carcinogenesis, 36 (4). pp. 487-497. Ma, S. and Venkatesh, A. and Langellotto, F. and Le, Y. Z. and Hall, M. N. and Rüegg, M. A. and Punzo, C.. (2015) Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival. Experimental Eye Research, 135. pp. 1-13. Oliveira, A. P. and Dimopoulos, S. and Busetto, A. G. and Christen, S. and Dechant, R. and Falter, L. and Haghir, C. M. and Jozefczuk, S. and Ludwig, C. and Rudroff, F. and Schulz, J. C. and González, A. and Soulard, A. and Stracka, D. and Aebersold, R. and Buhmann, J. M. and Hall, M. N. and Peter, M. and Sauer, U. and Stelling, J.. (2015) Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptome. Molecular systems biology, Vol. 11, H. 4. p. 802. Hindupur, Sravanth K. and González, Asier and Hall, Michael N.. (2015) The Opposing Actions of Target of Rapamycin and AMP-Activated Protein Kinase in Cell Growth Control. Cold Spring Harbor Perspectives in Biology, 7 (8). pp. 1-21. Albert, Verena and Cornu, Marion and Hall, Michael N.. (2015) mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior. Biochemical and Biophysical Research Communications, 464 (2). pp. 480-486. Albert, Verena and Hall, Michael N.. (2015) Reduced C/EBPβ-LIP translation improves metabolic health. EMBO reports, Vol. 16, H. 8. pp. 881-882. Drägert, Katja and Bhattacharya, Indranil and Pellegrini, Giovanni and Seebeck, Petra and Azzi, Abdelhalim and Brown, Steven A. and Georgiopoulou, Stavroula and Held, Ulrike and Blyszczuk, Przemyslaw and Arras, Margarete and Humar, Rok and Hall, Michael N. and Battegay, Edouard and Haas, Elvira. (2015) Deletion of Rictor in Brain and Fat Alters Peripheral Clock Gene Expression and Increases Blood Pressure. Hypertension, 66 (2). pp. 332-339. Cornu, Marion and de Caudron de Coquereaumont, Grégoire and Hall, Michael N.. (2015) mTOR signaling in liver disease. In: Signaling Pathways in Liver Diseases. West Sussex, pp. 314-325. Hindupur, Sravanth K. and González, Asier and Hall, Michael N.. (2015) The Opposing Actions of Target of Rapamycin and AMP-Activated Protein Kinase in Cell Growth Control. In: Size Control in Biology: From Organelles to Organisms. New York, pp. 221-240. 2014Chen, J. and Tu, X. and Esen, E. and Joeng, K. S. and Lin, C. and Arbeit, J. M. and Rüegg, M. A. and Hall, M. N. and Ma, L. and Long, F.. (2014) WNT7B promotes bone formation in part through mTORC1. PLoS Genetics, 10 (1). e1004145. Shimobayashi, M. and Hall, M. N.. (2014) Making new contacts : the mTOR network in metabolism and signalling crosstalk. Nature reviews. Molecular cell biology, Vol. 15, H. 3. pp. 155-162. Benjamin, D. and Hall, M. N.. (2014) mTORC1: Turning Off Is Just as Important as Turning On. Cell, 156 (4). pp. 627-628. Lebrun-Julien, F. and Bachmann, L. and Norrmén, C. and Trötzmüller, M. and Köfeler, H. and Rüegg, M. A. and Hall, M. N. and Suter, U.. (2014) Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination. Journal of Neuroscience, 34 (25). pp. 8432-8448. Umemura, A. and Park, E. J. and Taniguchi, K. and Lee, J. H. and Shalapour, S. and Valasek, M. A. and Aghajan, M. and Nakagawa, H. and Seki, E. and Hall, M. N. and Karin, M.. (2014) Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. Cell metabolism, Vol. 20, H. 1. pp. 133-144. Grahammer, F. and Haenisch, N. and Steinhardt, F. and Sander, L. and Roerden, M. and Arnold, F. and Cordts, T. and Wanner, N. and Reichardt, W. and Kerjaschki, D. and Ruegg, M. A. and Hall, M. N. and Moulin, P. and Busch, H. and Boerries, M. and Walz, G. and Artunc, F. and Huber, T. B.. (2014) mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress. Proceedings of the National Academy of Sciences of the United States of America, 111 (27). E2817-E2826. Zhang, Lianjun and Tschumi, Benjamin O. and Corgnac, Stéphanie and Rüegg, Markus A. and Hall, Michael N. and Mach, Jean-Pierre and Romero, Pedro and Donda, Alena. (2014) Mammalian target of rapamycin complex 1 orchestrates invariant NKT cell differentiation and effector function. Journal of Immunology, 193 (4). pp. 1759-1765. Cornu, M. and Oppliger, W. and Albert, V. and Robitaille, A. M. and Trapani, F. and Quagliata, L. and Fuhrer, T. and Sauer, U. and Terracciano, L. and Hall, M. N.. (2014) Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21. Proceedings of the National Academy of Sciences of the United States of America, 111 (32). pp. 11592-11599. Chou, Po-Chien and Oh, Won Jun and Wu, Chang-Chih and Moloughney, Joseph and Rüegg, Markus A. and Hall, Michael N. and Jacinto, Estela and Werlen, Guy. (2014) Mammalian target of rapamycin complex 2 modulates αβTCR processing and surface expression during thymocyte development. Journal of Immunology, 193 (3). pp. 1162-1170. Siamer, S. and Guillas, I. and Shimobayashi, M. and Kunz, C. and Hall, M. N. and Barny, M. A.. (2014) Expression of the bacterial type III effector DspA/E in Saccharomyces cerevisiae downregulates the sphingolipid biosynthetic pathway leading to growth-arrest. Journal of Biological Chemistry, 289 (26). pp. 18466-18477. de Cabo, R. and Carmona-Gutierrez, D. and Bernier, M. and Hall, M. N. and Madeo, F.. (2014) The Search for Antiaging Interventions : From Elixirs to Fasting Regimens. Cell, 157 (7). pp. 1515-1526. Norrmén, C. and Figlia, G. and Lebrun-Julien, F. and Pereira, J. A. and Trötzmüller, M. and Köfeler, H. C. and Rantanen, V. and Wessig, C. and van Deijk, A. F. and Smit, A. B. and Verheijen, M. G. and Rüegg, M. A. and Hall, M. N. and Suter, U.. (2014) mTORC1 Controls PNS Myelination along the mTORC1-RXRγ-SREBP-Lipid Biosynthesis Axis in Schwann Cells. Cell Reports , 9 (2). pp. 646-660. Stracka, Daniele and Jozefczuk, Szymon and Rudroff, Florian and Sauer, Uwe and Hall, Michael N.. (2014) Nitrogen Source Activates TOR (Target of Rapamycin) Complex 1 via Glutamine and Independently of Gtr/Rag Proteins. Journal of Biological Chemistry, 289 (36). pp. 25010-25020. Albert, V. and Hall, M. N.. (2014) mTOR signaling in cellular and organismal energetics. Current Opinion in Cell Biology, Vol. 33. pp. 55-66. 2013Cornu, Marion and Albert, Verena and Hall, Michael N.. (2013) mTOR in aging, metabolism, and cancer. Current Opinion in Genetics & Development, 23 (1). pp. 53-62. Bentzinger, C. Florian and Lin, Shuo and Romanino, Klaas and Castets, Perrine and Guridi, Maitea and Summermatter, Serge and Handschin, Christoph and Tintignac, Lionel A. and Hall, Michael N. and Rüegg, Markus A.. (2013) Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy. Skeletal muscle, Vol. 3, H. 1 , 6. Shimobayashi, M. and Oppliger, W. and Moes, S. and Jenö, P. and Hall, M. N.. (2013) TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis. Molecular Biology of the Cell, 24 (6). pp. 870-881. Robitaille, A. M. and Christen, S. and Shimobayashi, M. and Cornu, M. and Fava, L. L. and Moes, S. and Prescianotto-Baschong, C. and Sauer, U. and Jenoe, P. and Hall, M. N.. (2013) Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis. Science, 339 (6125). pp. 1320-1323. Saldivia, M. and Barquilla, A. and Bart, J. M. and Diaz-González, R. and Hall, M. N. and Navarro, M.. (2013) Target of rapamycin (TOR) kinase in Trypanosoma brucei : an extended family. Biochemical Society Transactions, 41 (4). pp. 934-938. Shortt, J. and Martin, B. P. and Newbold, A. and Hannan, K. M. and Devlin, J. R. and Baker, A. J. and Ralli, R. and Cullinane, C. and Schmitt, C. A. and Reimann, M. and Hall, M. N. and Wall, M. and Hannan, R. D. and Pearson, R. B. and McArthur, G. A. and Johnstone, R. W.. (2013) Combined inhibition of PI3K-related DNA-damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas. Blood, Vol. 121, H. 15. pp. 2964-2974. Bhattacharya, I. and Drägert, K. and Albert, V. and Contassot, E. and Damjanovic, M. and Hagiwara, A. and Zimmerli, L. and Humar, R. and Hall, M. N. and Battegay, E. J. and Haas, E.. (2013) Rictor in Perivascular Adipose Tissue Controls Vascular Function by Regulating Inflammatory Molecule Expression. Arteriosclerosis, thrombosis, and vascular biology, Vol. 33, H. 9. pp. 2105-2111. Sauer, E. and Imseng, S. and Maier, T. and Hall, M. N.. (2013) Conserved sequence motifs and the structure of the mTOR kinase domain. Biochemical Society Transactions, 41 (4). pp. 889-895. Thedieck, K. and Holzwarth, B. and Prentzell, M. T. and Boehlke, C. and Kläsener, K. and Ruf, S. and Sonntag, A. G. and Maerz, L. and Grellscheid, S. N. and Kremmer, E. and Nitschke, R. and Kuehn, E. W. and Jonker, J. W. and Groen, A. K. and Reth, M. and Hall, M. N. and Baumeister, R.. (2013) Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells. Cell, 154 (4). pp. 859-874. Hall, M. N.. (2013) On mTOR nomenclature. Biochemical Society Transactions, 41 (4). pp. 8817-8888. Betz, C. and Stracka, D. and Prescianotto-Baschong, C. and Frieden, M. and Demaurex, N. and Hall, M. N.. (2013) mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology. Proceedings of the National Academy of Sciences of the United States of America, 110 (31). pp. 12526-12534. Benjamin, D. and Hall, M. N.. (2013) TSC on the peroxisome controls mTORC1. Nature Cell Biology, Vol. 15, H. 10. pp. 1135-1136. Betz, C. and Hall, M. N.. (2013) Where is mTOR and what is it doing there? Journal of cell biology, Vol. 203, H. 4. pp. 563-574. Blazek, M. and Betz, C. and Reth, M. and Hall, M. N. and Zengerle, R. and Meier, M.. (2013) Proximity Ligation Assay for High Content Profiling of Cell Signaling Pathways on a Microfluidic Chip. Molecular & cellular proteomics, Vol. 12. pp. 3898-3907. Wyder Peters, L. and Molle, K. D. and Thiemeyer, A. and Knopf, A. and Goxe, M. and Guerry, P. and Brodbeck, D. and Colombi, M. and Hall, M. N. and Moroni, C. and Regenass, U.. (2013) An Isogenic Cell Panel Identifies Compounds That Inhibit Proliferation of mTOR-Pathway Addicted Cells by Different Mechanisms. Journal of Biomolecular Screening, 19 (1). pp. 131-144. 2012Cybulski, Nadine and Zinzalla, Vittoria and Hall, Michael N.. (2012) Inducible raptor and rictor Knockout Mouse Embryonic Fibroblasts. Methods in Molecular Biology, 821. pp. 267-278. Barquilla, A. and Saldivia, M. and Diaz, R. and Bart, J. -M. and Vidal, I. and Calvo, E. and Hall, M. N. and Navarro, M.. (2012) Third target of rapamycin complex negatively regulates development of quiescence in Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America, 109 (36). pp. 14399-14404. Hagiwara, Asami and Cornu, Marion and Cybulski, Nadine and Polak, Pazit and Betz, Charles and Trapani, Francesca and Terracciano, Luigi and Heim, Markus H. and Rüegg, Markus A. and Hall, Michael N.. (2012) Hepatic mTORC2 activates glycolysis and lipogenesis through akt, glucokinase, and SREBP1c. Cell Metabolism, 15 (5). pp. 725-738. Appenzeller-Herzog, Christian and Hall, Michael N.. (2012) Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling. Trends in Cell Biology, 22 (5). pp. 272-282. Durán, R. V. and Hall, M. N.. (2012) Leucyl-tRNA synthetase : double duty in amino acid sensing. Cell Research, 22 (8). pp. 1207-1209. Robitaille, A. M. and Hall, M. N.. (2012) Ramping up mitosis : an AMPKα2-regulated signaling network promotes mitotic progression. Molecular Cell, 45 (1). pp. 8-9. Durán, R. V. and Hall, M. N.. (2012) Regulation of TOR by small GTPases. EMBO Reports, 13 (2). pp. 121-128. Cardon, C. M. and Beck, T. and Hall, M. N. and Rutter, J.. (2012) PAS kinase promotes cell survival and growth through activation of Rho1. Science Signaling, 5 (209). ra9. Liu, Q. and Ren, T. and Fresques, T. and Oppliger, W. and Niles, B. J. and Hur, W. and Sabatini, D. M. and Hall, M. N. and Powers, T. and Gray, N. S.. (2012) Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae. ACS Chemical Biology, 7 (6). pp. 982-987. Durán, R. V. and Oppliger, W. and Robitaille, A. M. and Heiserich, L. and Skendaj, R. and Gottlieb, E. and Hall, M. N.. (2012) Glutaminolysis activates Rag-mTORC1 signaling. Molecular Cell, 47 (3). pp. 349-358. Durán, R. V. and Mackenzie, E. D. and Boulahbel, H. and Frezza, C. and Heiserich, L. and Tardito, S. and Bussolati, O. and Rocha, S. and Hall, M. N. and Gottlieb, E.. (2012) HIF-independent role of prolyl hydroxylases in the cellular response to amino acids. Oncogene, 32 (38). pp. 4549-4556. Durán, Raúl V. and Hall, Michael N.. (2012) Glutaminolysis feeds mTORC1. Cell Cycle, 11 (22). pp. 4107-4108. 2011Colombi, M. and Molle, K. D. and Benjamin, D. and Rattenbacher-Kiser, K. and Schaefer, C. and Betz, C. and Thiemeyer, A. and Regenass, U. and Hall, M. N. and Moroni, C.. (2011) Genome-wide shRNA screen reveals increased mitochondrial dependence upon mTORC2 addiction. Oncogene, 30 (13). pp. 1551-1565. Zinzalla, V. and Stracka, D. and Oppliger, W. and Hall, M. N.. (2011) Activation of mTORC2 by Association with the Ribosome. Cell, 144 (5). pp. 757-768. Inoki, K. and Mori, H. and Wang, J. and Suzuki, T. and Hong, S. and Yoshida, S. and Blattner, S. M. and Ikenoue, T. and Ruegg, M. A. and Hall, M. N. and Kwiatkowski, D. J. and Rastaldi, M. P. and Huber, T. B. and Kretzler, M. and Holzman, L. B. and Wiggins, R. C. and Guan, K. -L.. (2011) mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. Journal of Clinical Investigation, 121 (6). pp. 2181-2196. Hall, M. N.. (2011) Growth grows up COCB themed issue on cell division, growth, and death. Current Opinion in Cell Biology, 23 (6). pp. 705-706. Chan, J. C. and Hannan, K. M. and Riddell, K. and Ng, P. Y. and Peck, A. and Lee, R. S. and Hung, S. and Astle, M. V. and Bywater, M. and Wall, M. and Poortinga, G. and Jastrzbeski, K. and Sheppard, K. E. and Hemmings, B. A. and Hall, M. N. and Johnstone, R. W. and McArthur, G. A. and Hannan, R. D. and Pearson, R. B.. (2011) AKT is a critical regulator of rRNA synthesis and cooperates with c-MYC to control ribosome biogenesis in cancer. Science Signaling, 4 (188). ra56. Dazert, E. and Hall, M. N.. (2011) mTOR signaling in disease. Current Opinion in Cell Biology, 23 (6). pp. 744-755. Godel, M. and Hartleben, B. and Herbach, N. and Liu, S. and Zschiedrich, S. and Lu, S. and Debreczeni-Mor, A. and Lindenmeyer, M. T. and Rastaldi, M. -P. and Hartleben, G. and Wiech, T. and Fornoni, A. and Nelson, R. G. and Kretzler, M. and Wanke, R. and Pavenstadt, H. and Kerjaschki, D. and Cohen, C. D. and Hall, M. N. and Ruegg, M. A. and Inoki, K. and Walz, G. and Huber, T. B.. (2011) Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. Journal of Clinical Investigation, 121 (6). pp. 2197-2209. Shende, P. and Plaisance, I. and Morandi, C. and Pellieux, C. and Berthonneche, C. and Zorzato, F. and Krishnan, J. and Lerch, R. and Hall, M. N. and Ruegg, M. A. and Pedrazzini, T. and Brink, M.. (2011) Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice. Circulation, 123 (10). pp. 1073-1082. Loewith, R. and Hall, M. N.. (2011) Target of Rapamycin (TOR) in nutrient signaling and growth control. Genetics, 189 (4). pp. 1177-1201. Hall, M. N.. (2011) The history and perspectives of TOR research. Jikken Igaku (Experimental Medicine), Vol. 29. pp. 862-864. Benjamin, Don and Colombi, Marco and Moroni, Christoph and Hall, Michael N.. (2011) Rapamycin passes the torch: a new generation of mTOR inhibitors. Nature Reviews. Drug Discovery, 10 (11). pp. 868-880. 2010Thedieck, K. and Hall, M. N.. (2010) Translational control by amino acids and energy. In: Handbook of cell signaling, Vol. 3. San Diego, California, pp. 2285-2293. Cornu, M. and Hall, M. N.. (2010) mTORC1 and mTORC2 in energy homeostasis. In: Structure, function and regulation of TOR complexes from yeasts to mammals, Part B. Amsterdam, pp. 263-278. Blagosklonny, Mikhail V. and Campisi, Judy and Sinclair, David A. and Bartke, Andrzej and Blasco, Maria A. and Bonner, William M. and Bohr, Vilhelm A. and Brosh, Robert M. and Brunet, Anne and Depinho, Ronald A. and Donehower, Lawrence A. and Finch, Caleb E. and Finkel, Toren and Gorospe, Myriam and Gudkov, Andrei V. and Hall, Michael N. and Hekimi, Siegfried and Helfand, Stephen L. and Karlseder, Jan and Kenyon, Cynthia and Kroemer, Guido and Longo, Valter and Nussenzweig, Andre and Osiewacz, Heinz D. and Peeper, Daniel S. and Rando, Thomas A. and Rudolph, K. Lenhard and Sassone-Corsi, Paolo and Serrano, Manuel and Sharpless, Norman E. and Skulachev, Vladimir P. and Tilly, Jonathan L. and Tower, John and Verdin, Eric and Vijg, Jan. (2010) Impact papers on aging in 2009. Aging, 2 (3). pp. 111-121. Michels, A. A. and Robitaille, A. M. and Buczynski-Ruchonnet, D. and Hodroj, W. and Reina, J. H. and Hall, M. N. and Hernandez, N.. (2010) mTORC1 directly phosphorylates and regulates human MAF1. Molecular and cellular biology, Vol. 30, H. 15. pp. 3749-3757. Soulard, A. and Cremonesi, A. and Moes, S. and Schutz, F. and Jeno, P. and Hall, M. N.. (2010) The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates. Molecular Biology of the Cell, 21 (19). pp. 3475-3486. Zinzalla, V. and Sturgill, T. W. and Hall, . (2010) TOR complexes : composition, structure and phosphorylation. In: Structure, function and regulation of TOR complexes from yeasts to mammals, Part A. Amsterdam, pp. 1-20. Tamanoi, F. and Hall, M. N., eds. (2010) Structure, Function and Regulation of TOR Complexes from Yeasts to Mammals. The enzymes, Vol. 27-28. Amsterdam. 2009Polak, P. and Hall, M. N.. (2009) mTOR and the control of whole body metabolism. Current Opinion in Cell Biology, 21 (2). pp. 209-218. Cohen, A. and Hall, M. N.. (2009) An amino acid shuffle activates mTORC1. Cell, 136 (3). pp. 399-400. Soulard, A. and Cohen, A. and Hall, M. N.. (2009) TOR signaling in invertebrates. Current Opinion in Cell Biology, 21 (6). pp. 825-836. Cybulski, N. and Polak, P. and Auwerx, J. and Ruegg, M. A. and Hall, M. N.. (2009) mTOR complex 2 in adipose tissue negatively controls whole-body growth. Proceedings of the National Academy of Sciences of the United States of America, 106 (24). pp. 9902-9907. Patursky-Polischuk, I. and Stolovich-Rain, M. and Hausner-Hanochi, M. and Kasir, J. and Cybulski, N. and Avruch, J. and Ruegg, M. A. and Hall, M. N. and Meyuhas, O.. (2009) The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner. Molecular and cellular biology, Vol. 29, H. 3. pp. 640-649. Cybulski, N. and Hall, M. N.. (2009) TOR complex 2 : a signaling pathway of its own. Trends in Biochemical Sciences, 34 (12). pp. 620-627. Sturgill, T. W. and Hall, M. N.. (2009) Activating Mutations in TOR Are in Similar Structures As Oncogenic Mutations in PI3KCalpha. ACS chemical biology, Vol. 4, no. 12. pp. 999-1015. Blagosklonny, Mikhail V. and Hall, Michael N.. (2009) Growth and aging : a common molecular mechanism. Aging, Vol. 1, H. 4. pp. 357-362. 2008Jiang, H. and Schiffer, E. and Song, Z. and Wang, J. and Zurbig, P. and Thedieck, K. and Moes, S. and Bantel, H. and Saal, N. and Jantos, J. and Brecht, M. and Jeno, P. and Hall, M. N. and Hager, K. and Manns, M. P. and Hecker, H. and Ganser, A. and Dohner, K. and Bartke, A. and Meissner, C. and Mischak, H. and Ju, Z. and Rudolph, K. L.. (2008) Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease. Proceedings of the National Academy of Sciences of the United States of America, 105 (32). pp. 11299-11304. Zinzalla, V. and Hall, M. N.. (2008) Signal transduction : linking nutrients to growth. Nature, 454. pp. 287-288. Sturgill, T. W. and Cohen, A. and Diefenbacher, M. and Trautwein, M. and Martin, D. E. and Hall, M. N.. (2008) TOR1 and TOR2 have distinct locations in live cells. Eukaryotic Cell, Vol. 7, H. 10. pp. 1819-1830. Polak, P. and Cybulski, N. and Feige, J. N. and Auwerx, J. and Ruegg, M. A. and Hall, M. N.. (2008) Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration. Cell Metabolism, Vol. 8, H. 5. pp. 399-410. Bentzinger, C. F. and Romanino, K. and Cloetta, D. and Lin, S. and Mascarenhas, J. B. and Oliveri, F. and Xia, J. and Casanova, E. and Costa, C. F. and Brink, M. and Zorzato, F. and Hall, M. N. and Ruegg, M. A.. (2008) Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metabolism, Vol. 8, H. 5. pp. 411-424. Gander, S. and Bonenfant, D. and Altermatt, P. and Martin, D. E. and Hauri, S. and Moes, S. and Hall, M. N. and Jenoe, P.. (2008) Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase. Rapid communications in mass spectrometry, Vol. 22, H. 23. pp. 3743-3753. Hall, M. N.. (2008) mTOR - what does it do? Transplantation proceedings, 40 (10). S5-S8. Robitaille, A. M. and Hall, M. N.. (2008) mTor. UCSD Nature Molecular Pages, 2008, A000094. 2007Urban, J. and Soulard, A. and Huber, A. and Lippman, S. and Mukhopadhyay, D. and Deloche, O. and Wanke, V. and Anrather, D. and Ammerer, G. and Riezman, H. and Broach, J. R. and De Virgilio, C. and Hall, M. N. and Loewith, R.. (2007) Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. Molecular cell, Vol. 26, H. 5. pp. 663-674. Soulard, A. and Hall, M. N.. (2007) SnapShot : mTOR signaling. Cell, 129 (2). p. 434. Sturgill, T. W. and Hall, M. N.. (2007) Holding back TOR advances mitosis. Nature Cell Biology, Vol. 9, H. 11. pp. 1221-1222. Thedieck, K. and Polak, P. and Kim, M. L. and Molle, K. D. and Cohen, A. and Jeno, P. and Arrieumerlou, C. and Hall, M. N.. (2007) PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. PLoS one, Vol. 2, H. 11 , e1217. Li, Weimin and Petrimpol, Marco and Molle, Klaus D. and Hall, Michael N. and Battegay, Edouard J. and Humar, Rok. (2007) Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2. Circulation Research, 100 (1). pp. 79-87. 2006Mulet, J. M. and Martin, D. E. and Loewith, R. and Hall, M. N.. (2006) Mutual antagonism of target of rapamycin and calcineurin signaling. Journal of Biological Chemistry, 281 (44). pp. 33000-33007. Polak, P. and Hall, M. N.. (2006) mTORC2 Caught in a SINful Akt. Developmental cell, Vol. 11, H. 4. pp. 433-434. Wullschleger, S. and Loewith, R. and Hall, M. N.. (2006) TOR signaling in growth and metabolism. Cell, 124 (3). pp. 471-484. Honma, Yoshimi and Kitamura, Aiko and Shioda, Ryo and Maruyama, Hironori and Ozaki, Kanako and Oda, Yoko and Mini, Thierry and Jenö, Paul and Maki, Yasushi and Yonezawa, Kazuyoshi and Hurt, Ed and Ueno, Masaru and Uritani, Masahiro and Hall, Michael N. and Ushimaru, Takashi. (2006) TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients. The EMBO Journal, 25 (16). pp. 3832-3842. Wahl, Patricia R. and Serra, Andreas L. and Le Hir, Michel and Molle, Klaus D. and Hall, Michael N. and Wüthrich, Rudolf P.. (2006) Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD). Nephrology Dialysis Transplantation, 21 (3). pp. 598-604. Martin, D. E. and Powers, T. and Hall, M. N.. (2006) Regulation of ribosome biogenesis : where is TOR? Cell Metabolism, Vol. 4, H. 4. pp. 259-260. Linder, P. and Shore, D. and Hall, M. N., eds. (2006) Landmark papers in yeast biology. New York. 2005Kamada, Y. and Fujioka, Y. and Suzuki, N. N. and Inagaki, F. and Wullschleger, S. and Loewith, R. and Hall, M. N. and Ohsumi, Y.. (2005) Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization. Molecular and Cellular Biology, Vol. 25, H. 16. pp. 7239-7248. Wullschleger, S. and Loewith, R. and Oppliger, W. and Hall, M. N.. (2005) Molecular organization of target of rapamycin complex 2. Journal of Biological Chemistry, 280 (35). pp. 30697-30704. Dames, S. A. and Mulet, J. M. and Rathgeb-Szabo, K. and Hall, M. N. and Grzesiek, S.. (2005) The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. Journal of Biological Chemistry, 280 (21). pp. 20558-20564. Martin, D. E. and Hall, M. N.. (2005) The expanding TOR signaling network. Current Opinion in Cell Biology, 17 (2). pp. 158-166. 2004Burri, L. and Vascotto, K. and Fredersdorf, S. and Tiedt, R. and Hall, M. N. and Lithgow, T.. (2004) Zim17 : a novel zinc finger protein essential for protein import into mitochondria. Journal of Biological Chemistry, 279 (48). pp. 50243-50249. Martin, D. E. and Soulard, A. and Hall, M. N.. (2004) TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell, 119 (7). pp. 969-979. Martin, D. E. and Demougin, P. and Hall, M. N. and Bellis, M.. (2004) Rank difference analysis of microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data. BMC bioinformatics, Vol. 5 , 148. Morales-Johansson, H. and Jenoe, P. and Cooke, F. T. and Hall, M. N.. (2004) Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4. Journal of Biological Chemistry, 279 (38). pp. 39604-39610. Schmelzle, T. and Beck, T. and Martin, D. E. and Hall, M. N.. (2004) Activation of the RAS/cyclic AMP pathway suppresses a TOR deficiency in yeast. Molecular and cellular biology, Vol. 24, H. 1. pp. 338-351. Jacinto, E. and Loewith, R. and Schmidt, A. and Lin, S. and Ruegg, M. A. and Hall, A. and Hall, M. N.. (2004) Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nature Cell Biology, Vol. 6, H. 11. pp. 1122-1128. Audhya, Anjon and Loewith, Robbie and Parsons, Ainslie B. and Gao, Lu and Tabuchi, Mitsuaki and Zhou, Huilin and Boone, Charles and Hall, Michael N. and Emr, Scott D.. (2004) Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton. The EMBO Journal, 23 (19). pp. 3747-3757. Crespo, J. L. and Helliwell, S. B. and Wiederkehr, C. and Demougin, P. and Fowler, B. and Primig, M. and Hall, M. N.. (2004) NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae. Journal of Biological Chemistry, 279 (36). pp. 37512-37517. Schmelzle, T. and Crespo, J. L. and Hall, M. N.. (2004) Translational control by amino acids and energy. In: Handbook of cell signaling, Vol. 3. San Diego, California, pp. 299-303. Loewith, R. and Hall, M. N.. (2004) TOR signaling in yeast : temporal and spatial control of cell growth. In: Cell growth. New York, pp. 139-166. Hall, M. N. and Raff, M. and Thomas, G., eds. (2004) Cell growth : control of cell size. Cold Spring Harbor monograph series, 42. New York. Thomas, George and Sabatini, David M. and Hall, Michael N., eds. (2004) TOR : target of rapamycin. Current topics in microbiology and immunology, 279. Heidelberg. Lorberg, A. and Hall, M. N.. (2004) TOR - the first 10 years. Current Topics in Microbiology and Immunology, 279. pp. 1-18. 2003Jacinto, E. and Hall, M. N.. (2003) Tor signalling in bugs, brain and brawn. Nature reviews. Molecular cell biology, Vol. 4, H. 2. pp. 117-126. Bonenfant, D. and Schmelzle, T. and Jacinto, E. and Crespo, J. L. and Mini, T. and Hall, M. N. and Jenoe, P.. (2003) Quantitation of changes in protein phosphorylation : a simple method based on stable isotope labeling and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America, 100 (3). pp. 880-885. 2002Crespo, J. L. and Hall, M. N.. (2002) Elucidating TOR signaling and rapamycin action : lessons from Saccharomyces cerevisiae. Microbiology and molecular biology reviews, Vol. 66, H. 4. pp. 579-591. Loewith, R. and Jacinto, E. and Wullschleger, S. and Lorberg, A. and Crespo, J. L. and Bonenfant, D. and Oppliger, W. and Jenoe, P. and Hall, M. N.. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Molecular cell, Vol. 10, H. 3. pp. 457-468. Desrivieres, S. and Cooke, F. T. and Morales-Johansson, H. and Parker, P. J. and Hall, M. N.. (2002) Calmodulin controls organization of the actin cytoskeleton via regulation of phosphatidylinositol (4,5)-bisphosphate synthesis in Saccharomyces cerevisiae. Biochemical Journal, 366 (3). pp. 945-951. Schmidt, A. and Schmelzle, T. and Hall, M. N.. (2002) The RHO1-GAPs SAC7, BEM2 and BAG7 control distinct RHO1 functions in Saccharomyces cerevisiae. Molecular Microbiology, 45 (5). pp. 1433-1441. Crespo, J. L. and Powers, T. and Fowler, B. and Hall, M. N.. (2002) The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine. Proceedings of the National Academy of Sciences of the United States of America, 99 (10). pp. 6784-6789. Schmelzle, T. and Helliwell, S. B. and Hall, M. N.. (2002) Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast. Molecular and Cellular Biology, Vol. 22, H. 5. pp. 1329-1339. 2001Jacinto, E. and Guo, B. and Arndt, K. T. and Schmelzle, T. and Hall, M. N.. (2001) TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Molecular cell, Vol. 8, H. 5. pp. 1017-1026. Friant, S. and Lombardi, R. and Schmelzle, T. and Hall, M. N. and Riezman, H.. (2001) Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast. The EMBO Journal, 20 (23). pp. 6783-6792. Crespo, J. L. and Daicho, K. and Ushimaru, T. and Hall, M. N.. (2001) The GATA transcription factors GLN3 and GAT1 link TOR to salt stress in Saccharomyces cerevisiae. Journal of Biological Chemistry, 276 (37). pp. 34441-34444. Hall, M. N. and Sabatini, D. M.. (2001) TOR and Control of Cell Growth. In: Cahiers de la Fondation des Treilles, 13. Paris, pp. 62-82. Beck, T. and Delley, P. A. and Hall, M. N.. (2001) Control of the actin cytoskeleton by extracellular signals. In: Molecular interactions of actin, Vol. 1: Actin structure and actin-binding proteins. Heidelberg, pp. 231-262. 2000Brachat, A. and Liebundguth, N. and Rebischung, C. and Lemire, S. and Scharer, F. and Hoepfner, D. and Demchyshyn, V. and Howald, I. and Dusterhoft, A. and Mostl, D. and Pohlmann, R. and Kotter, P. and Hall, M. N. and Wach, A. and Philippsen, P.. (2000) Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames. Yeast, 16 (3). pp. 241-253. Cosentino, G. P. and Schmelzle, T. and Haghighat, A. and Helliwell, S. B. and Hall, M. N. and Sonenberg, N.. (2000) Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Molecular and Cellular Biology, Vol. 20, H. 13. pp. 4604-4613. Kunz, J. and Schneider, U. and Howald, I. and Schmidt, A. and Hall, M. N.. (2000) HEAT repeats mediate plasma membrane localization of Tor2p in yeast. 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(1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature, 402. pp. 689-692. Delley, P. A. and Hall, M. N.. (1999) Cell wall stress depolarizes cell growth via hyperactivation of RHO1. The Journal of cell biology, Vol. 147, H. 1. pp. 163-174. Beck, T. and Schmidt, A. and Hall, M. N.. (1999) Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast. The Journal of cell biology, Vol. 146, H. 6. pp. 1227-1238. 1998Cooke, F. T. and Dove, S. K. and McEwen, R. K. and Painter, G. and Holmes, A. B. and Hall, M. N. and Michell, R. H. and Parker, P. J.. (1998) The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. Current Biology, 8 (22). pp. 1219-1222. Schmidt, A. and Hall, M. N.. (1998) Signaling to the actin cytoskeleton. Annual review of cell and developmental biology, Vol. 14. pp. 305-338. Schmidt, A. and Beck, T. and Koller, A. and Kunz, J. and Hall, M. N.. (1998) The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease. The EMBO Journal, 17 (23). pp. 6924-6931. Helliwell, S. B. and Schmidt, A. and Ohya, Y. and Hall, M. N.. (1998) The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton. Current Biology, 8 (22). pp. 1211-1214. Desrivieres, S. and Cooke, F. T. and Parker, P. J. and Hall, M. N.. (1998) MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae. Journal of Biological Chemistry, 273 (25). pp. 15787-15793. Bickle, M. and Delley, P. A. and Schmidt, A. and Hall, M. N.. (1998) Cell wall integrity modulates RHO1 activity via the exchange factor ROM2. The EMBO Journal, 17 (8). pp. 2235-2245. Helliwell, S. B. and Howald, I. and Barbet, N. and Hall, M. N.. (1998) TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae. Genetics, 148 (1). pp. 99-112. 1997Thomas, G. and Hall, M. N.. (1997) TOR signalling and control of cell growth. Current Opinion in Cell Biology, 9 (6). pp. 782-787. Schmidt, A. and Bickle, M. and Beck, T. and Hall, M. N.. (1997) The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Cell, 88 (4). pp. 531-542. 1996Barbet, N. C. and Schneider, U. and Helliwell, S. B. and Stansfield, I. and Tuite, M. F. and Hall, M. N.. (1996) TOR controls translation initiation and early G1 progression in yeast. Molecular Biology of the Cell, 7 (1). pp. 25-42. Hall, M. N.. (1996) Drug discovery : rational serendipity. Trends in Biochemical Sciences, 21 (8). pp. 322-323. Beretta, L. and Gingras, A. C. and Svitkin, Y. V. and Hall, M. N. and Sonenberg, N.. (1996) Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. The EMBO Journal, 15 (3). pp. 658-664. Schmidt, A. and Kunz, J. and Hall, M. N.. (1996) TOR2 is required for organization of the actin cytoskeleton in yeast. Proceedings of the National Academy of Sciences of the United States of America, 93 (24). pp. 13780-13785. Hall, M. N.. (1996) The TOR signalling pathway and growth control in yeast. Biochemical Society Transactions, 24 (1). pp. 234-239. Hall, M. N.. (1996) Yeast cloning book cloning. Trends in Cell Biology, 6 (2). p. 80. Koller, A. and Heitman, J. and Hall, M. N.. (1996) Regional bivalent-univalent pairing versus trivalent pairing of a trisomic chromosome in Saccharomyces cerevisiae. Genetics, 144 (3). pp. 957-966. 1994Garcia-Bustos, J. F. and Marini, F. and Stevenson, I. and Frei, C. and Hall, M. N.. (1994) PIK1, an essential phosphatidylinositol 4-kinase associated with the yeast nucleus. The EMBO Journal, 13 (10). pp. 2352-2361. Hottiger, T. and De Virgilio, C. and Hall, M. N. and Boller, T. and Wiemken, A.. (1994) The role of trehalose synthesis for the acquisition of thermotolerance in yeast : II. Physiological concentrations of trehalose increase the thermal stability of proteins in vitro. European Journal of Biochemistry, 219 (1-2). pp. 187-193. Schmidt, A. and Hall, M. N. and Koller, A.. (1994) Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Molecular and Cellular Biology, Vol. 14, H. 10. pp. 6597-6606. Helliwell, S. B. and Wagner, P. and Kunz, J. and Deuter-Reinhard, M. and Henriquez, R. and Hall, M. N.. (1994) TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Molecular Biology of the Cell, 5 (1). pp. 105-118. Hall, M. N.. (1994) Cytosplasm-to-nucleus signaling in yeast: use of immunosuppressive drugs as probes. In: Trafic des Protéines chez les Microorganismes. Paris, pp. 55-57. 1993Heitman, J. and Koller, A. and Kunz, J. and Henriquez, R. and Schmidt, A. and Movva, N. R. and Hall, M. N.. (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Molecular and cellular biology, Vol. 13, H. 8. pp. 5010-5019. Kunz, J. and Henriquez, R. and Schneider, U. and Deuter-Reinhard, M. and Movva, N. R. and Hall, M. N.. (1993) Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell, 73 (3). pp. 585-596. Wagner, P. and Hall, M. N.. (1993) Nuclear protein transport is functionally conserved between yeast and higher eukaryotes. FEBS Letters, 321 (2-3). pp. 261-266. Kunz, J. and Hall, M. N.. (1993) Cyclosporin A, FK506 and rapamycin : more than just immunosuppression. Trends in Biochemical Sciences, 18 (9). pp. 334-348. Heitman, J. and Koller, A. and Cardenas, M. E. and Hall, M. N.. (1993) Identification of immunosuppressive drug targets in yeast. Methods, Vol. 5, no. 2. pp. 176-187. Hall, M. N. and Linder, P. and Hall, M. N., eds. (1993) The early days of yeast genetics. New York. 1992Davis, E. S. and Becker, A. and Heitman, J. and Hall, M. N. and Brennan, M. B.. (1992) A yeast cyclophilin gene essential for lactate metabolism at high temperature. Proceedings of the National Academy of Sciences of the United States of America, 89 (23). pp. 11169-11173. Tinland, B. and Koukolíková-Nicola, Z. and Hall, M. N. and Hohn, B.. (1992) The T-DNA-linked VirD2 protein contains two distinct functional nuclear localization signals. Proceedings of the National Academy of Sciences of the United States of America, 89 (16). pp. 7442-7446. Heitman, J. and Movva, N. R. and Hall, M. N.. (1992) Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression. The New Biologist, Vol. 4, no. 5. pp. 448-460. 1991Garcia-Bustos, J. F. and Wagner, P. and Hall, M. N.. (1991) Yeast cell-free nuclear protein import requires ATP hydrolysis. Experimental Cell Research, 192 (1). pp. 213-219. Garcia-Bustos, J. and Heitman, J. and Hall, M. N.. (1991) Nuclear protein localization. Biochimica et Biophysica Acta, 1071 (1). pp. 83-101. Garcia-Bustos, J. F. and Wagner, P. and Hall, M. N.. (1991) Nuclear import substrates compete for a limited number of binding sites : evidence for different classes of yeast nuclear import receptors. Journal of Biological Chemistry, 266 (33). pp. 22303-22306. Heitman, J. and Movva, N. R. and Hiestand, P. C. and Hall, M. N.. (1991) FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America, 88 (5). pp. 1948-1952. Heitman, J. and Movva, N. R. and Hall, M. N.. (1991) Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science, 253 (5022). pp. 905-909. Tinland, B. and Hall, M. N. and Hohn, B.. (1991) Mechanism of T-DNA transfer. In: Proceedings of the 5th International Symposium on the molecular genetics of plant-microbe interactions, Interlaken, Switzerland, September 9-14, 1990. Dordrecht, pp. 79-84. 1990Hall, M. N. and Craik, C. and Hiraoka, Y.. (1990) Homeodomain of yeast repressor alpha 2 contains a nuclear localization signal. Proceedings of the National Academy of Sciences of the United States of America, 87 (18). pp. 6954-6958. Wagner, P. and Kunz, J. and Koller, A. and Hall, M. N.. (1990) Active transport of proteins into the nucleus. FEBS Letters, 275 (1-2). pp. 1-5. 1988Silver, P. A. and Hall, M. N.. (1988) Transport of proteins into the nucleus. In: Protein transfer and organelle biogenesis. San Diego, Calif., pp. 749-769. Hall, M. N. and Fried, S. R.. (1988) Is nuclear protein localization receptor-mediated? In: Molecular Biology of Intracellular Protein Sorting and Organelle Assembly. New York, pp. 187-192. 1987Benson, S. A. and Hall, M. N. and Rasmussen, B. A.. (1987) Signal sequence mutations that alter coupling of secretion and translation of an Escherichia coli outer membrane protein. Journal of bacteriology, Vol. 169, H. 10. pp. 4686-4691. Hall, M. N. and Johnson, A. D.. (1987) Homeo domain of the yeast repressor alpha 2 is a sequence-specific DNA-binding domain but is not sufficient for repression. Science, 237 (4818). pp. 1007-1012. 1986Hall, M. N.. (1986) Considerations on the mechanism of nuclear protein localization in yeast. In: Nucleocytoplasmic transport. Heidelberg, pp. 247-252. Garcia-Bustos, J. and Heitman, J. and Hall, M. N.. (1986) Nuclear protein localization signals in yeast. In: Yeast cell biology (UCLA-Symposia on molecular and cellular biology, N.S. Vol. 33). Alan R. Liss, Inc., pp. 421-425. 1985Hall, M. N.. (1985) Studies on the mechanism of nuclear protein localization in yeast. In: Protein transport and secretion. New York, pp. 196-200. Benson, S. A. and Hall, M. N. and Silhavy, T. J.. (1985) Genetic analysis of protein export in Escherichia coli K12. Annual Review of Biochemistry, 54. pp. 101-134. Silhavy, T. J. and Benson, S. A. and Hall, M. N.. (1985) A mechanism to couple transport and export. In: Microbiology - 1985. Washington, pp. 454-458. 1984Hall, M. N. and Hereford, L. and Herskowitz, I.. (1984) Targeting of E. coli beta-galactosidase to the nucleus in yeast. Cell, 36 (4). pp. 1057-1065. Berman, M. L. and Jackson, D. E. and Fowler, A. and Zabin, I. and Christensen, L. and Fiil, N. P. and Hall, M. N.. (1984) Gene fusion techniques: Cloning vectors for manipulating IacZ gene fusions. Gene Analysis Techniques, 1 (3). pp. 43-51. 1983Hall, M. N. and Gabay, J. and Schwartz, M.. (1983) Evidence for a coupling of synthesis and export of an outer membrane protein in Escherichia coli. The EMBO Journal, 2 (1). pp. 15-19. Taylor, R. K. and Hall, M. N. and Silhavy, T. J.. (1983) Isolation and characterization of mutations altering expression of the major outer membrane porin proteins using the local anaesthetic procaine. Journal of Molecular Biology, 166 (3). pp. 273-282. 1982Benson, S. and Emr, S. and Hall, M. and Silhavy, T. and Sodergren, E.. (1982) Genetic approaches to study export of LamB to the outer membrane. Annales de Microbiologie, Vol. 133a, H. 1. pp. 115-122. Hall, M. N. and Schwartz, M. and Silhavy, T. J.. (1982) Sequence information within the lamB genes in required for proper routing of the bacteriophage lambda receptor protein to the outer membrane of Escherichia coli K-12. Journal of Molecular Biology, 156 (1). pp. 93-112. Hall, M. N. and Gabay, J. and Debarbouille, M. and Schwartz, M.. (1982) A role for mRNA secondary structure in the control of translation initiation. Nature, 295. pp. 616-618. Hall, M. N. and Schwartz, M.. (1982) Reconsidering the early steps of protein secretion. Annales de Microbiologie, 133a (1). pp. 123-127. 1981Hall, M. N. and Silhavy, T. J.. (1981) Genetic analysis of the major outer membrane proteins of Escherichia coli. Annual Review of Genetics, 15. pp. 91-142. Hall, M. N. and Silhavy, T. J.. (1981) The ompB locus and the regulation of the major outer membrane porin proteins of Escherichia coli K12. Journal of Molecular Biology, 146 (1). pp. 23-43. Hall, M. N. and Silhavy, T. J.. (1981) Genetic analysis of the ompB locus in Escherichia coli K-12. Journal of Molecular Biology, 151 (1). pp. 1-15. Taylor, R. K. and Hall, M. N. and Enquist, L. and Silhavy, T. J.. (1981) Identification of OmpR : a positive regulatory protein controlling expression of the major outer membrane matrix porin proteins of Escherichia coli K-12. Journal of bacteriology, Vol. 147, H. 1. pp. 255-258. Hall, M. N. and Emr, S. D. and Silhavy, T. J.. (1981) Genetic studies on mechanisms of protein localization in Escherichia coli K-12. In: Membrane transport and neuroreceptors. New York, pp. 81-97. 1980Emr, S. D. and Hall, M. N. and Silhavy, T. J.. (1980) A mechanism of protein localization : the signal hypothesis and bacteria. The Journal of cell biology, Vol. 86, H. 3. pp. 701-711. Moreno, F. and Fowler, A. V. and Hall, M. and Silhavy, T. J. and Zabin, I. and Schwartz, M.. (1980) A signal sequence is not sufficient to lead beta-galactosidase out of the cytoplasm. Nature, Vol. 286. pp. 356-359. Hall, M. N. and Emr, S. D. and Silhavy, T. J.. (1980) Genetic studies on mechanisms of protein localization in Escherichia coli K-12. Journal of Supramolecular Structure, 13 (2). pp. 147-163. 1979Hall, M. N. and Silhavy, T. J.. (1979) Transcriptional regulation of Escherichia coli K-12 major outer membrane protein 1b. Journal of bacteriology, Vol. 140, H. 2. pp. 342-350. |
