Browse by Basel Contributors ID

Bonifacio, Annalisa and Sanvee, Gerda M. and Brecht, Karin and Kratschmar, Denise V. and Odermatt, Alex and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes. Archives of Toxicology, 91 (5). pp. 2223-2234.

Bloechliger, Marlene and Ceschi, Alessandro and Rüegg, Stephan and Kupferschmidt, Hugo and Krähenbühl, Stephan and Jick, Susan S. and Meier, Christoph R. and Bodmer, Michael. (2016) Risk of Seizures Associated with Antidepressant Use in Patients with Depressive Disorder: Follow-up Study with a Nested Case-Control Analysis Using the Clinical Practice Research Datalink. Drug Safety , 39 (4). pp. 307-321.

Camblin, Marine and Berger, Benjamin and Haschke, Manuel and Krähenbühl, Stephan and Huwyler, Jörg and Puchkov, Maxim. (2016) CombiCap: A novel drug formulation for the basel phenotyping cocktail. International Journal of Pharmaceutics, 512 (1). pp. 253-261.

Haegler, Patrizia and Grünig, David and Berger, Benjamin and Krähenbühl, Stephan and Bouitbir, Jamal. (2015) Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: a cell model for idiosyncratic toxicity. Toxicology, 336. pp. 48-58.

Welzenbach, Karl and Mancuso, Riccardo V. and Krähenbühl, Stephan and Weitz-Schmidt, Gabriele. (2015) A novel multi-parameter assay to dissect the pharmacological effects of different modes of integrin αLβ2 inhibition in whole blood. British journal of pharmacology, 172 (20). pp. 4875-4887.

Roberts, Paul A. and Bouitbir, Jamal and Bonifacio, Annalisa and Singh, François and Kaufmann, Priska and Urwyler, Albert and Krähenbühl, Stephan. (2015) Contractile function and energy metabolism of skeletal muscle in rats with secondary carnitine deficiency. American journal of physiology. Gastrointestinal and liver physiology, 309 (3). E265-E274.

Liakoni, Evangelia and Rätz Bravo, Alexandra E. and Krähenbühl, Stephan. (2015) Hepatotoxicity of New Oral Anticoagulants (NOACs). Drug safety, 38 (8). pp. 711-720.

Bonifacio, Annalisa and Sanvee, Gerda M. and Bouitbir, Jamal and Krähenbühl, Stephan. (2015) The AKT/mTOR signaling pathway plays a key role in statin-induced myotoxicity. Biochimica et biophysica acta, 1853 (8). pp. 1841-1849.

Singh, François and Charles, Anne-Laure and Schlagowski, Anna-Isabel and Bouitbir, Jamal and Bonifacio, Annalisa and Piquard, François and Krähenbühl, Stephan and Geny, Bernard and Zoll, Joffrey. (2015) Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis. Biochimica et biophysica acta. Molecular cell research, 1853 (7). pp. 1574-1585.

Ceschi, Alessandro and Heistermann, Elja and Gros, Sonja and Reichert, Cornelia and Kupferschmidt, Hugo and Banner, Nicholas R. and Krähenbühl, Stephan and Taegtmeyer, Anne B.. (2015) Acute sirolimus overdose: a multicenter case series. PLoS one, 10 (5). e0128033.

Sidharta, Patricia N. and Krähenbühl, Stephan and Dingemanse, Jasper. (2015) Pharmacokinetic and pharmacodynamic evaluation of macitentan , a novel endothelin receptor antagonist for the treatment of pulmonary arterial hypertension. Expert opinion on drug metabolism & toxicology, 11 (3). pp. 437-449.

Blaser, Lea S. and Tramonti, Alexandra and Egger, Pascal and Haschke, Manuel and Krähenbühl, Stephan and Rätz Bravo, Alexandra E.. (2015) Hematological safety of metamizole: retrospective analysis of WHO and Swiss spontaneous safety reports. European journal of clinical pharmacology, 71 (2). pp. 209-217.

Siller-Matula, J. M. and Trenk, D. and Krähenbühl, S. and Michelson, A. D. and Delle-Karth, G.. (2014) Clinical implications of drug-drug interactions with P2Y12 receptor inhibitors. Journal of thrombosis and haemostasis, Vol. 12, H. 1. pp. 2-13.

Detampel, Pascal and Witzigmann, Dominik and Krähenbühl, Stephan and Huwyler, Jörg. (2014) Hepatocyte targeting using pegylated asialofetuin-conjugated liposomes. Journal of drug targeting, Vol. 22, No. 3. pp. 232-241.

Morand, Réjane and Bouitbir, Jamal and Felser, Andrea and Hench, Jürgen and Handschin, Christoph and Frank, Stephan and Krähenbühl, Stephan. (2014) Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice. European journal of nutrition, Vol. 53, H. 6. pp. 1313-1325.

Mengiardi, Seraina and Tsakiris, Dimitrios A. and Molnar, Viviane and Kohlhaas-Styk, Urs and Mittag, Michael and Kraehenbuehl, Stephan and Hersberger, Kurt E.. (2014) Impact of pharmaceutical care on self-administration of outpatient low-molecular-weight heparin therapy. Pharmacology & pharmacy, Vol. 5, H. 4. pp. 372-385.

Donzelli, Massimiliano and Derungs, Adrian and Serratore, Maria-Giovanna and Noppen, Christoph and Nezic, Lana and Krähenbühl, Stephan and Haschke, Manuel. (2014) The Basel Cocktail for Simultaneous Phenotyping of Human Cytochrome P450 Isoforms in Plasma, Saliva and Dried Blood Spots. Clinical pharmacokinetics, Vol. 53, H. 3. pp. 271-282.

Felser, Andrea and Lindinger, Peter W. and Schnell, Dominik and Kratschmar, Denise V. and Odermatt, Alex and Mies, Suzette and Jenö, Paul and Krähenbühl, Stephan. (2014) Hepatocellular toxicity of benzbromarone : Effects on mitochondrial function and structure. Toxicology, Vol. 324. pp. 136-146.

Taegtmeyer, Anne B. and Haschke, Manuel and Tchambaz, Lydia and Buylaert, Mirabel and Tschöpl, Martin and Beuers, Ulrich and Drewe, Jürgen and Krähenbühl, Stephan. (2014) A study of the relationship between serum bile acids and propranolol pharmacokinetics and pharmacodynamics in patients with liver cirrhosis and in healthy controls. PLoS one, Vol. 9, H. 6 , e97885.

Felser, Andrea and Stoller, Andrea and Morand, Réjane and Schnell, Dominik and Donzelli, Massimiliano and Terracciano, Luigi and Bouitbir, Jamal and Krähenbühl, Stephan. (2014) Hepatic toxicity of dronedarone in mice : role of mitochondrial β-oxidation. Toxicology, Vol. 323. pp. 1-9.

Nezic, Lana and Derungs, Adrian and Bruggisser, Marcel and Tschudin-Sutter, Sarah and Krähenbühl, Stephan and Haschke, Manuel. (2014) Therapeutic drug monitoring of once daily aminoglycoside dosing : comparison of two methods and investigation of the optimal blood sampling strategy. European journal of clinical pharmacology, Vol. 70, H. 7. pp. 829-837.

Wuillemin, Natascha and Terracciano, Luigi and Beltraminelli, Helmut and Schlapbach, Christoph and Fontana, Stefano and Krähenbühl, Stephan and Pichler, Werner J. and Yerly, Daniel. (2014) T cells infiltrate the liver and kill hepatocytes in HLA-B(∗)57:01-associated floxacillin-induced liver injury. American journal of pathology, Vol. 184, no. 6. pp. 1677-1682.

Ceschi, Alessandro and Gregoriano, Claudia and Rauber-Lüthy, Christine and Kupferschmidt, Hugo and Banner, Nicholas R. and Krähenbühl, Stephan and Taegtmeyer, Anne B.. (2014) Acute mycophenolate overdose : case series and systematic literature analysis. Expert opinion on drug safety, Vol. 13, H. 5. pp. 525-534.

Gregoriano, Claudia and Ceschi, Alessandro and Rauber-Lüthy, Christine and Kupferschmidt, Hugo and Banner, Nicholas R. and Krähenbühl, Stephan and Taegtmeyer, Anne B.. (2014) Acute thiopurine overdose : analysis of reports to a National Poison Centre 1995-2013. PLoS one, Vol. 9, H. 1 , e86390.

Liakoni, Evangelia and Rätz Bravo, Alexandra E. and Terracciano, Luigi and Heim, Markus and Krähenbühl, Stephan. (2014) Symptomatic hepatocellular liver injury with hyperbilirubinemia in two patients treated with rivaroxaban. JAMA internal medicine, Vol. 174, H. 10. pp. 1683-1686.

Ceschi, A. and Rauber-Lüthy, C. and Kupferschmidt, H. and Banner, N. R. and Ansari, M. and Krähenbühl, S. and Taegtmeyer, A. B.. (2013) Acute Calcineurin Inhibitor Overdose: Analysis of Cases Reported to a National Poison Center Between 1995 and 2011. American journal of transplantation : official journal of the American Society of Transplant Surgeons (ASTS) and the American Society of Transplantation (AST), Vol. 13 , S. 786–795.

Felser, Andrea and Blum, Kim and Lindinger, Peter W. and Bouitbir, Jamal and Krähenbühl, Stephan. (2013) Mechanisms of hepatocellular toxicity associated with dronedarone -a comparison to amiodarone. Toxicological Sciences, Vol. 131, H. 2. pp. 480-490.

Mueller, F. and Büchel, B. and Köberle, D. and Schürch, S. and Pfister, B. and Krähenbühl, St and Froehlich, T. K. and Largiader, C. R. and Joerger, M.. (2013) Gender-specific elimination of continuous-infusional 5-fluorouracil in patients with gastrointestinal malignancies: results from a prospective population pharmacokinetic study. Cancer chemotherapy and pharmacology, Vol. 71, H. 2. pp. 361-370.

Franz, Carmen C. and Hildbrand, Carole and Born, Christa and Egger, Sabin and Rätz Bravo, Alexandra E. and Krähenbühl, Stephan. (2013) Dose adjustment in patients with liver cirrhosis : impact on adverse drug reactions and hospitalizations. European journal of clinical pharmacology, Vol. 69, H. 8. pp. 1565-1573.

Morand, Réjane and Donzelli, Massimiliano and Haschke, Manuel and Krähenbühl, Stephan. (2013) Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction. Analytical and bioanalytical chemistry, Vol. 405, H. 27. pp. 8829-8836.

Hirzel, E. and Lindinger, P. W. and Maseneni, S. and Giese, M. and Rhein, V. V. and Eckert, A. and Hoch, M. and Krahenbuhl, S. and Eberle, A. N.. (2013) Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytes. Journal of receptors and signal transduction, Vol. 33, H. 5. pp. 304-312.

Haschke, Manuel and Schuster, Manfred and Poglitsch, Marko and Loibner, Hans and Salzberg, Marc and Bruggisser, Marcel and Penninger, Joseph and Krähenbühl, Stephan. (2013) Pharmacokinetics and pharmacodynamics of recombinant human angiotensin-converting enzyme 2 in healthy human subjects. Clinical pharmacokinetics, Vol. 52, H. 9. pp. 783-792.

Wuillemin, Natascha and Adam, Jacqueline and Fontana, Stefano and Krähenbühl, Stephan and Pichler, Werner J. and Yerly, Daniel. (2013) HLA haplotype determines hapten or p-i T cell reactivity to flucloxacillin. Journal of immunology, Vol. 190, H. 10. pp. 4956-4964.

Maseneni, S. and Donzelli, M. and Brecht, K. and Krahenbuhl, S.. (2013) Toxicity of thienopyridines on human neutrophil granulocytes and lymphocytes. Toxicology, Vol. 308. pp. 11-19.

Giger-Pabst, Urs and Lange, Jochen and Maurer, Christoph and Bucher, Carine and Schreiber, Vital and Schlumpf, Rolf and Kocher, Thomas and Schweizer, Walter and Krähenbühl, Stephan and Krähenbühl, Lukas. (2013) Short-term preoperative supplementation of an immunoenriched diet does not improve clinical outcome in well-nourished patients undergoing abdominal cancer surgery. Nutrition, Vol. 29, H. 5. pp. 724-729.

Caduff Good, Angela and Nobel, Daniel and Krähenbühl, Stephan and Geisen, Christof and Henz, Samuel. (2013) Randomised trial of a clinical dosing algorithm to start anticoagulation with phenprocoumon. Swiss medical weekly, Vol. 143 , w13709.

Krähenbühl, Stephan. (2013) Leicht erhöhte Transaminasen. Therapeutische Umschau, Vol. 70, H. 5. pp. 284-288.

Zahno, A. and Bouitbir, J. and Maseneni, S. and Lindinger, P. W. and Brecht, K. and Krahenbuhl, S.. (2013) Hepatocellular toxicity of clopidogrel: Mechanisms and risk factors. Free radical biology & medicine, Vol. 65. pp. 208-216.

Hysek, C. M. and Simmler, L. D. and Nicola, V. G. and Vischer, N. and Donzelli, M. and Krahenbuhl, S. and Grouzmann, E. and Huwyler, J. and Hoener, M. C. and Liechti, M. E.. (2012) Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study. PLoS one, Vol. 7, H. 5 , e36476.

Pham, T. T. T. and See, H. H. and Morand, R. and Krahenbuhl, S. and Hauser, P. C.. (2012) Determination of free and total valproic acid in human plasma by capillary electrophoresis with contactless conductivity detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, Vol. 907. pp. 74-78.

See, Hong Heng and Schmidt-Marzinkowski, Julia and Pormsila, Worapan and Morand, Réjane and Krähenbühl, Stephan and Hauser, Peter C.. (2012) Determination of creatine and phosphocreatine in muscle biopsy samples by capillary electrophoresis with contactless conductivity detection. Analytica Chimica Acta, 727. pp. 78-82.

Franz, Carmen C. and Egger, Sabin and Born, Christa and Rätz Bravo, Alexandra E. and Krähenbühl, Stephan. (2012) Potential drug-drug interactions and adverse drug reactions in patients with liver cirrhosis. European journal of clinical pharmacology, Vol. 68, H. 2. pp. 179-188.

Henkel, Verena and Casaulta, Flurina and Seemüller, Florian and Krähenbühl, Stephan and Obermeier, Michael and Hüsler, Jürg and Möller, Hans-Jürgen. (2012) Study design features affecting outcome in antidepressant trials. Journal of affective disorders, Vol. 141, H. 2-3. pp. 160-167.

Detampel, Pascal and Beck, Mareike and Krähenbühl, Stephan and Huwyler, Jörg. (2012) Drug interaction potential of resveratrol. Drug metabolism reviews, Vol. 44, H. 3. pp. 253-265.

Morand, R. and Todesco, L. and Donzelli, M. and Fischer-Barnicol, D. and Mullen, P. J. and Krahenbuhl, S.. (2012) Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans. Therapeutic drug monitoring, Vol. 34, H. 4. pp. 406-414.

Hardmeier, M. and Zimmermann, R. and Ruegg, S. and Pfluger, M. and Deuster, S. and Suter, K. and Donzelli, M. and Drewe, J. and Krahenbuhl, S. and Fuhr, P. and Haschke, M.. (2012) Intranasal midazolam: pharmacokinetics and pharmacodynamics assessed by quantitative EEG in healthy volunteers. Clinical pharmacology and therapeutics, Vol. 91, H. 5. pp. 856-862.

Maseneni, S. and Donzelli, M. and Taegtmeyer, A. B. and Brecht, K. and Krahenbuhl, S.. (2012) Toxicity of clopidogrel and ticlopidine on human myeloid progenitor cells: importance of metabolites. Toxicology, Vol. 299, H. 2-3. pp. 139-145.

Joerger, M. and Ferreri, A. J. M. and Krähenbühl, S. and Schellens, J. H. M. and Cerny, Th and Zucca, E. and Huitema, A. D. R.. (2012) Dosing algorithm to target a predefined AUC in patients with primary central nervous system lymphoma receiving high dose methotrexate. British journal of clinical pharmacology, Vol. 73, H. 2. pp. 240-247.

Nezic, L. and Krähenbühl, S. and Rätz Bravo, A. E.. (2012) Diclofenac-induzierte Leberschäden = Diclofenac induced liver injuries. Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine PRAXIS, Vol. 101, H. 6. pp. 371-379.

Swiss Association for the Study of the Liver, and Moradpour D, Helbling B. and Cerny A, De Gottardi A. and Heim MH, Majno P. and Müllhaupt B, Negro F. and Rubbia-Brandt L, Semela D. and Vilei SB, Bernsmeier C. and Bihl F, Borovicka J. and Dill M, Dufour J. F. and Filipowicz M, Geier A. and Gerlach T, Giostra E. and Gonvers JJ, Goossens N. and Gubler C, Hadengue A. and Heim MH, Helbling B. and Hellstern M, Hirschi C. and Jochum W, Krähenbühl S. and Kullak-Ublick G, Lange C. and Lavanchy D, Majno P. and Malinverni R, McLin V. and Mentha G, Mertens J. C. and Nasser S, Oneta C. and Pache I, Rubbia-Brandt L. and Sauter B, Semela D. and Spahr L, Steuerwald M. and Stickel F, Stieger B. and Wehr K, Zala G.. (2012) Treatment of chronic hepatitis C genotype 1 with triple therapy comprising telaprevir or boceprevir. Swiss medical weekly, Vol. 142 , w13516.

Kummer, Oliver and Hammann, Felix and Moser, Claudine and Schaller, Olivier and Drewe, Jürgen and Krähenbühl, Stephan. (2011) Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. European journal of clinical pharmacology, Vol. 67, H. 1. pp. 63-71.

Zahno, Anja and Brecht, Karin and Morand, Réjane and Maseneni, Swarna and Török, Michael and Lindinger, Peter W. and Krähenbühl, Stephan. (2011) The role of CYP3A4 in amiodarone-associated toxicity on HepG2 cells. Biochemical pharmacology, Vol. 81, Issue 3. pp. 432-441.

Pormsila, Worapan and Morand, Réjane and Krähenbühl, Stephan and Hauser, Peter C.. (2011) Capillary electrophoresis with contactless conductivity detection for the determination of carnitine and acylcarnitines in clinical samples. Journal of Chromatography B, 879 (13-14). pp. 921-926.

Pormsila, Worapan and Morand, Réjane and Krähenbühl, Stephan and Hauser, Peter C.. (2011) Quantification of plasma lactate concentrations using capillary electrophoresis with contactless conductivity detection. Electrophoresis, 32 (8). pp. 884-889.

Derungs, A. and Schietzel, S. and Meyer, M. R. and Maurer, H. H. and Krahenbuhl, S. and Liechti, M. E.. (2011) Sympathomimetic toxicity in a case of analytically confirmed recreational use of naphyrone (naphthylpyrovalerone). Clinical toxicology, Vol. 49, H. 7. pp. 691-693.

Halter, J. and Schüpbach, W. M. M. and Casali, C. and Elhasid, R. and Fay, K. and Hammans, S. and Illa, I. and Kappeler, L. and Krähenbühl, S. and Lehmann, T. and Mandel, H. and Marti, R. and Mattle, H. and Orchard, K. and Savage, D. and Sue, C. M. and Valcarcel, D. and Gratwohl, A. and Hirano, M.. (2011) Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) : a consensus conference proposal for a standardized approach. Bone marrow transplantation, Vol. 46, H. 3. pp. 330-337.

Hoch, Matthias and Hoever, Petra and Haschke, Manuel and Krähenbühl, Stephan and Dingemanse, Jasper. (2011) Food effect and biocomparison of two formulations of the dual orexin receptor antagonist almorexant in healthy male subjects. The journal of clinical pharmacology, Vol. 51, H. 7. pp. 1116-1121.

Bruggisser, M. and Rätz Bravo, A. E. and Krähenbühl, S.. (2011) [Severe pancytopenia and stomatitis in a patient treated with low-dose methostraxate]. Schweizerische Rundschau für Medizin PRAXIS, Vol. 100, H. 13 , S. 765-774; quiz 772.

Franz, C. C. and Bruggisser, M. and Krähenbühl, S. and Rätz Bravo, A. E.. (2011) [Rhabdomyolysis associated with atorvastatin combined with amiodarone and fluconazole]. Schweizerische Rundschau für Medizin PRAXIS, Vol. 100, H. 5. pp. 273-284.

Mullen, P. J. and Zahno, A. and Lindinger, P. and Maseneni, S. and Felser, A. and Krähenbühl, S. and Brecht, K.. (2011) Susceptibility to simvastatin-induced toxicity is partly determined by mitochondrial respiration and phosphorylation state of Akt. Biochimica et biophysica acta, Vol. 1813, H. 12. pp. 2079-2087.

Giger, U. and Ouaissi, M. and Schmitz, S.-F H. and Krähenbühl, S. and Krähenbühl, L.. (2011) Bile duct injury and use of cholangiography during laparoscopic cholecystectomy. British journal of surgery, Vol. 98, H. 3. pp. 391-396.

Poller, Birk and Drewe, Jürgen and Krähenbühl, Stephan and Huwyler, Jörg and Gutmann, Heike. (2010) Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier. Cellular and Molecular Neurobiology, Vol. 30, No. 1. pp. 63-70.

Brauchli, Yolanda B. and Wais, Thomas and Gratwohl, Alois and Heim, Dominik and Schipf, Alexander and Diebold, Joachim and Krähenbühl, Stephan. (2010) Fatal myocardial infarction during nilotinib treatment in a 60-year-old male patient. Acta oncologica, Vol. 49, no. 4. pp. 523-525.

Pormsila, W. and Krähenbühl, S. and Hauser, P. C.. (2010) Determination of carnitine in food and food supplements by capillary electrophoresis with contactless conductivity detection. Electrophoresis, Vol. 31. pp. 2186-2191.

Pormsila, W. and Gong, X. Y. and Hauser, P. C.. (2010) Determination of the enantiomers of alpha-hydroxy- and alpha-amino acids in capillary electrophoresis with contactless conductivity detection. Electrophoresis, Vol. 31. pp. 2044-2048.

Sawatzki, M. and Kummer, O. and Krähenbühl, S. and Siegemund, M.. (2010) 35-jährige Patientin mit generalisiertem Krampfanfall und nicht-kardiogenem Lungenödem nach Intoxikation. Internist, 51 (4). pp. 528-532.

Bodmer, Michael and Meier, Christian and Krähenbühl, Stephan and Jick, Susan S. and Meier, Christoph R.. (2010) Long-term metformin use is associated with decreased risk of breast cancer. Diabetes care, Vol. 33, H. 6. pp. 1304-1308.

Haschke, Manuel and Suter, Katja and Hofmann, Sarah and Witschi, Robert and Fröhlich, Johannes and Imanidis, Georgios and Drewe, Jürgen and Briellmann, Thomas A. and Dussy, Franz E. and Krähenbühl, Stephan and Surber, Christian. (2010) Pharmacokinetics and pharmacodynamics of nasally delivered midazolam. British journal of clinical pharmacology, Vol. 69, H. 6. pp. 607-616.

Egger, S. S. and Meier, S. and Leu, C. and Christen, S. and Gratwohl, A. and Krahenbuhl, S. and Haschke, M.. (2010) Drug interactions and adverse events associated with antimycotic drugs used for invasive aspergillosis in hematopoietic SCT. Bone marrow transplantation, Vol. 45, H. 7. pp. 1197-1203.

Haschke, M. and Vitins, T. and Lude, S. and Todesco, L. and Novakova, K. and Herrmann, R. and Krahenbuhl, S.. (2010) Urinary excretion of carnitine as a marker of proximal tubular damage associated with platin-based antineoplastic drugs. Nephrology, dialysis, transplantation, Vol. 25, H. 2. pp. 426-433.

Joerger, M. and Huitema, A. D. R. and Krähenbühl, S. and Schellens, J. H. M. and Cerny, T. and Reni, M. and Zucca, E. and Cavalli, F. and Ferreri, A. J. M.. (2010) Methotrexate area under the curve is an important outcome predictor in patients with primary CNS lymphoma : a pharmacokinetic-pharmacodynamic analysis from the IELSG no. 20 trial. British journal of cancer, Vol. 102, H. 4. pp. 673-677.

Mullen, Peter James and Lüscher, Barbara and Scharnagl, Hubert and Krähenbühl, Stephan and Brecht, Karin. (2010) Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy. Biochemical pharmacology, Vol. 79, Issue 8. pp. 1200-1209.

Grisouard, Jean and Timper, Katharina and Radimerski, Tanja M. and Frey, Daniel M. and Peterli, Ralph and Kola, Blerina and Korbonits, Marta and Herrmann, Paul and Krahenbuhl, Stephan and Zulewski, Henryk and Keller, Ulrich and Muller, Beat and Christ-Crain, Mirjam. (2010) Mechanisms of metformin action on glucose transport and metabolism in human adipocytes. Biochemical Pharmacology, 80 (11). pp. 1736-1745.

Zahno, Anja and Brecht, Karin and Bodmer, Michael and Bur, Daniel and Tsakiris, Dimitrios A. and Krähenbühl, Stephan. (2010) Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro. British journal of pharmacology, Vol. 161, no. 2. pp. 393-404.

Schürch, Regula and Todesco, Liliane and Novakova, Katarina and Mevissen, Meike and Stieger, Bruno and Krähenbühl, Stephan. (2010) The plasma carnitine concentration regulates renal OCTN2 expression and carnitine transport in rats. European journal of pharmacology, Vol. 635, H. 1-3. pp. 171-176.

Krämer, Isabel and Rauber-Lüthy, Christine and Kupferschmidt, Hugo and Krähenbühl, Stephan and Ceschi, Alessandro. (2010) Minimal dose for severe poisoning and influencing factors in acute human clozapine intoxication : a 13-year retrospective study. Clinical neuropharmacology, Vol. 33, H. 5. pp. 230-234.

Popov, Yury and Sverdlov, Deanna Y. and Bhaskar, K. Ramakrishnan and Sharma, Anisha K. and Millonig, Gunda and Patsenker, Eleonora and Krahenbuhl, Stephan and Krahenbuhl, Lukas and Schuppan, Detlef. (2010) Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis. American journal of physiology. Gastrointestinal and liver physiology, Vol. 298, H. 3 , G323-334.

Bodmer, Michael and Brauchli, Yolanda B. and Krähenbühl, Stephan and Jick, Susan S. and Meier, Christoph R.. (2009) Statin use and risk of gallstone disease followed by cholecystectomy. JAMA : the journal of the American Medical Association, Vol. 302, H. 18. pp. 2001-2007.

Kummer, Oliver and Haschke, Manuel and Hammann, Felix and Bodmer, Michael and Bruderer, Shirin and Regnault, Yann and Dingemanse, Jasper and Krähenbühl, Stephan. (2009) Comparison of the dissolution and pharmacokinetic profiles of two galenical formulations of the endothelin receptor antagonist macitentan. European journal of pharmaceutical sciences, Vol. 38, H. 4. pp. 384-388.

Sidharta, P. N. and Rave, K. and Heinemann, L. and Chiossi, E. and Krahenbuhl, S. and Dingemanse, J.. (2009) Effect of the urotensin-II receptor antagonist palosuran on secretion of and sensitivity to insulin in patients with Type 2 diabetes mellitus. British journal of clinical pharmacology, Vol. 68, no. 4. pp. 502-510.

Rätz Bravo, Alexandra E. and Hofer, Silvia and Krähenbühl, Stephan and Ludwig, Christian. (2009) Fatal drug-drug interaction of brivudine and capecitabine. Acta oncologica, Vol. 48, no. 4. pp. 631-633.

Giger, U. and Wente, M. N. and Büchler, M. W. and Krähenbühl, S. and Lerut, J. and Krähenbühl, L.. (2009) Endoscopic retroperitoneal neurectomy for chronic pain after groin surgery. British journal of surgery, Vol. 96, H. 9. pp. 1076-1081.

Schlatter, Chantal and Egger, Sabin S. and Tchambaz, Lydia and Krähenbühl, Stephan. (2009) Pharmacokinetic changes of psychotropic drugs in patients with liver disease : implications for dose adaptation. Drug safety, Vol. 32, no. 7. pp. 561-578.

Todesco, Liliane and Bodmer, Michael and Vonwil, Karin and Häussinger, Daniel and Krähenbühl, Stephan. (2009) Interaction between pivaloylcarnitine and L-carnitine transport into L6 cells overexpressing hOCTN2. Chemico-Biological Interactions , 180 (3). pp. 472-477.

Pormsila, W. and Krahenbuhl, S. and Hauser, P. C.. (2009) Capillary electrophoresis with contactless conductivity detection for uric acid determination in biological fluids. Analytica Chimica Acta, Vol. 636, pp. 224-228.

Knapp, Andrea Caroline and Todesco, Liliane and Beier, Konstantin and Terracciano, Luigi and Saegesser, Hans and Reichen, Juerg and Kraehenbuehl, Stephan. (2008) Toxicity of valproic acid in mice with decreased plasma and tissue carnitine stores. The Journal of Pharmacology and Experimental Therapeutics, Vol. 324, H. 2. pp. 568-575.

Knapp, Andrea Caroline and Todesco, Liliane and Torok, Michael and Beier, Konstantin and Krähenbühl, Stephan. (2008) Effect of carnitine deprivation on carnitine homeostasis and energy metabolism in mice with systemic carnitine deficiency. Annals of nutrition and metabolism, Vol. 52, No. 2. pp. 136-144.

Brauchli, Yolanda B. and Gittermann, Matthias and Michot, Marc and Krähenbühl, Stephan and Gnehm, Hanspeter E.. (2008) A fatal tick bite occurring during the course of tick-borne encephalitis vaccination. Pediatric infectious disease journal, Vol. 27. pp. 363-365.

Vonbach, Priska and Dubied, André and Krähenbühl, Stephan and Beer, Jürg H.. (2008) Prevalence of drug-drug interactions at hospital entry and during hospital stay of patients in internal medicine. European journal of internal medicine, Vol. 19, H. 6. pp. 413-420.

Bodmer, M. and Meier, C. and Krähenbühl, S. and Jick, S. S. and Meier, C. R.. (2008) Metformin, sulfonylureas, or other antidiabetes drugs and the risk of lactic acidosis or hypoglycemia : a nested case-control analysis. Diabetes Care, Vol. 31. pp. 2086-2091.

Brauchli, Yolanda B. and Scholer, André and Schwietert, Martin and Krähenbühl, Stephan. (2008) Undetectable phenytoin serum levels by an automated particle-enhanced turbidimetric inhibition immunoassay in a patient with monoclonal IgM lambda. Clinica chimica acta, Vol. 389, H. 1-2. pp. 174-176.

Poller, B. and Gutmann, H. and Krähenbühl, S. and Weksler, B. and Romero, I. and Couraud, P. O. and Tuffin, G. and Drewe, J. and Huwyler, J.. (2008) The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies. Journal of Neurochemistry, Vol. 107, H. 5. pp. 1358-1368.

Todesco, L. and Bur, D. and Brooks, H. and Török, M. and Landmann, L. and Stieger, B. and Krähenbühl, S.. (2008) Pharmacological manipulation of L-carnitine transport into L6 cells with stable overexpression of human OCTN2. Cellular and molecular life sciences, Vol. 65, no. 10. pp. 1596-1608.

Bodmer, M. and Burkard, T. and Kummer, O. and Beyrau, R. and Krähenbühl, S. and Haschke, M.. (2008) Pharmacokinetics and pharmacodynamics of quetiapine in a patient with a massive overdose. Therapeutic drug monitoring, Vol. 30, H. 4. pp. 553-556.

Lüde, Saskia and Török, Michael and Dieterle, Sandy and Jäggi, René and Büter, Karin Berger and Krähenbühl, Stephan. (2008) Hepatocellular toxicity of kava leaf and root extracts. Phytomedicine, Vol. 15, H. 1-2. pp. 120-131.

Vonbach, Priska and Dubied, André and Krähenbühl, Stephan and Beer, Jürg H.. (2008) Evaluation of frequently used drug interaction screening programs. Pharmacy world & science, Vol. 30, H. 4. pp. 367-374.

Aschmann, Yvonne Zysset and Kummer, Oliver and Linka, André and Wenk, Markus and Azzola, Andrea and Bodmer, Michael and Krähenbühl, Stephan and Haschke, Manuel. (2008) Pharmacokinetics and pharmacodynamics of sildenafil in a patient treated with human immunodeficiency virus protease inhibitors. Therapeutic drug monitoring, Vol. 30, H. 1. pp. 130-134.

Kummer, O. and Hammann, F. and Bodmer, M. and Novakova, K. and Krähenbühl, S. and Haschke, M.. (2008) [Drug-induced toxic hepatitis]. Schweizerische Rundschau für Medizin PRAXIS, Vol. 97 , S. 235-239 ; quiz 240-241.

Waldhauser, K. M. and Brecht, K. and Hebeisen, S. and Ha, H. R. and Konrad, D. and Bur, D. and Krähenbühl, S.. (2008) Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues. British journal of pharmacology, Vol. 155, no. 4. pp. 585-595.

Bodmer, M. and Link, B. and Grignaschi, N. and Kummer, O. and Ruegg, S. and Haschke, M. and Krähenbühl, S.. (2008) Pharmacokinetics of midazolam and metabolites in a patient with refractory status epilepticus treated with extraordinary doses of midazolam. Therapeutic drug monitoringNew York : Raven Press, Vol. 30, H. 1. pp. 120-124.

Botomino, Andrea and Bruppacher, Rudolf and Krähenbühl, Stephan and Hersberger, Kurt E.. (2008) Change of body weight and lifestyle of persons at risk for diabetes after screening and counselling in pharmacies. Pharmacy world & science, Vol. 30, H. 3. pp. 222-226.

Huwyler, J. and Drewe, J. and Krähenbuhl, S.. (2008) Tumor targeting using liposomal antineoplastic drugs. International Journal of Nanomedicine, 3 (1). pp. 21-29.

Schnyder, Anita and Krähenbühl, Stephan and Drewe, Jürgen and Huwyler, Jörg. (2005) Targeting of daunomycin using biotinylated immunoliposomes: Pharmacokinetics, tissue distribution and in vitro pharmacological effects. Journal of Drug Targeting, 13 (5). pp. 325-335.