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2016Makowska, Zuzanna and Boldanova, Tujana and Adametz, David and Quagliata, Luca and Vogt, Julia E. and Dill, Michael T. and Matter, Mathias S. and Roth, Volker and Terracciano, Luigi and Heim, Markus H.. (2016) Gene expression analysis of biopsy samples reveals critical limitations of transcriptome-based molecular classifications of hepatocellular carcinoma. The Journal of Pathology : Clinical Research , 2 (2). pp. 80-92. 2014Dill, Michael T. and Makowska, Zuzanna and Trincucci, Gaia and Gruber, Andreas J. and Vogt, Julia E. and Filipowicz, Magdalena and Calabrese, Diego and Krol, Ilona and Lau, Daryl T. and Terracciano, Luigi and van Nimwegen, Erik and Roth, Volker and Heim, Markus H.. (2014) Pegylated IFN-α regulates hepatic gene expression through transient Jak/STAT activation. Journal of Clinical Investigation, Vol. 124, H. 4. pp. 1568-1581. Haid, S. and Grethe, C. and Dill, M. T. and Heim, M. and Kaderali, L. and Pietschmann, T.. (2014) Isolate-dependent use of Claudins for cell entry by hepatitis C virus. Hepatology, Vol. 59, No. 1. pp. 24-34. Rothweiler, S. and Terracciano, L. and Tornillo, L. and Dill, M. T. and Heim, M. H. and Semela, D.. (2014) Downregulation of the Endothelial Genes Notch1 and EphrinB2 in Patients with Nodular Regenerative Hyperplasia. Liver international, Vol. 34, H. 4. pp. 594-603. Rothweiler, S. and Heim, M. H. and Semela, D.. (2014) Nodular regenerative hyperplasia in a patient with generalized essential telangiectasia : endotheliopathy as causal factor. Hepatology, Vol. 59, No. 6. pp. 2419-2421. Frentzen, A. and Anggakusuma, and Gurlevik, E. and Hueging, K. and Knocke, S. and Ginkel, C. and Brown, R. J. and Heim, M. and Dill, M. T. and Kroger, A. and Kalinke, U. and Kaderali, L. and Kuehnel, F. and Pietschmann, T.. (2014) Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells. Hepatology, Vol. 59, No. 1. pp. 78-88. Quagliata, L. and Matter, M. S. and Piscuoglio, S. and Arabi, L. and Ruiz, C. and Procino, A. and Kovac, M. and Moretti, F. and Makowska, Z. and Boldanova, T. and Andersen, J. B. and Hammerle, M. and Tornillo, L. and Heim, M. H. and Diederichs, S. and Cillo, C. and Terracciano, L. M.. (2014) lncRNA HOTTIP / HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients. Hepatology, Vol. 59, No. 3. pp. 911-923. Wieland, S. and Makowska, Z. and Campana, B. and Calabrese, D. and Dill, M. T. and Chung, J. and Chisari, F. V. and Heim, M. H.. (2014) Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver. Hepatology, Vol. 59, No. 6. pp. 2121-2130. Morikawa, K. and Gouttenoire, J. and Hernandez, C. and Thi, V. L. and Tran, H. T. and Lange, C. M. and Dill, M. T. and Heim, M. H. and Donze, O. and Penin, F. and Quadroni, M. and Moradpour, D.. (2014) Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. Hepatology, Vol. 59, No. 2. pp. 423-433. Frei, P. and Leucht, A. K. and Held, U. and Kofmehl, R. and Manser, C. N. and Schmitt, J. and Mertens, J. and Rau, M. and Baur, K. and Gerlach, T. and Negro, F. and Heim, M. and Moradpour, D. and Cerny, A. and Dufour, J. F. and Mullhaupt, B. and Geier, A.. (2014) Elderly age is not a negative predictive factor for virological response to therapy with pegylated interferon-alpha and ribavirin in chronic hepatitis C virus patients. Liver international, Vol. 34, H. 4. pp. 551-557. Duong, F. H. and Dill, M. T. and Matter, M. S. and Makowska, Z. and Calabrese, D. and Dietsche, T. and Ketterer, S. and Terracciano, L. and Heim, M. H.. (2014) Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53. Carcinogenesis, Vol. 35, H. 1. pp. 114-122. 2013Dill, M. T. and Tornillo, L. and Fritzius, T. and Terracciano, L. and Semela, D. and Bettler, B. and Heim, M. H. and Tchorz, J. S.. (2013) Constitutive Notch2 signaling induces hepatic tumors in mice. Hepatology, Vol. 57, No. 4. pp. 1607-1619. Heim, M. H.. (2013) Innate immunity and HCV. Journal of hepatology, Vol. 58, H. 3. pp. 564-574. Lange, C. M. and Miki, D. and Ochi, H. and Nischalke, H. D. and Bojunga, J. and Bibert, S. and Morikawa, K. and Gouttenoire, J. and Cerny, A. and Dufour, J. F. and Gorgievski-Hrisoho, M. and Heim, M. H. and Malinverni, R. and Mullhaupt, B. and Negro, F. and Semela, D. and Kutalik, Z. and Muller, T. and Spengler, U. and Berg, T. and Chayama, K. and Moradpour, D. and Bochud, P. Y.. (2013) Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development. PLoS one, Vol. 8, H. 5 , e64053. Zeuzem, S. and Asselah, T. and Angus, P. and Zarski, J. P. and Larrey, D. and Mullhaupt, B. and Gane, E. and Schuchmann, M. and Lohse, A. W. and Pol, S. and Bronowicki, J. P. and Roberts, S. and Arasteh, K. and Zoulim, F. and Heim, M. and Stern, J. O. and Nehmiz, G. and Kukolj, G. and Bocher, W. O. and Mensa, F. J.. (2013) Faldaprevir (BI 201335), BI 207127 and ribavirin oral therapy for treatment-naive HCV genotype 1 : SOUND-C1 final results. Antiviral therapy, Vol. 18, H. 8. pp. 1015-1019. Lupberger, J. and Duong, F. H. and Fofana, I. and Zona, L. and Xiao, F. and Thumann, C. and Durand, S. C. and Pessaux, P. and Zeisel, M. B. and Heim, M. H. and Baumert, T. F.. (2013) Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha. Hepatology, Vol. 58, No. 4. pp. 1225-1235. Heim, M. H.. (2013) 25 years of interferon-based treatment of chronic hepatitis C : an epoch coming to an end. Nature reviews. Immunology, Vol. 13, H. 7. pp. 535-542. Lange, C. M. and Bibert, S. and Dufour, J. F. and Cellerai, C. and Cerny, A. and Heim, M. H. and Kaiser, L. and Malinverni, R. and Mullhaupt, B. and Negro, F. and Semela, D. and Moradpour, D. and Kutalik, Z. and Bochud, P. Y.. (2013) Comparative genetic analyses point to HCP5 as susceptibility locus for HCV-associated hepatocellular carcinoma. Journal of hepatology, Vol. 59, H. 3. pp. 504-509. Zona, L. and Lupberger, J. and Sidahmed-Adrar, N. and Thumann, C. and Harris, H. J. and Barnes, A. and Florentin, J. and Tawar, R. G. and Xiao, F. and Turek, M. and Durand, S. C. and Duong, F. H. and Heim, M. H. and Cosset, F. L. and Hirsch, I. and Samuel, D. and Brino, L. and Zeisel, M. B. and Le Naour, F. and McKeating, J. A. and Baumert, T. F.. (2013) HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex. Cell host & microbe, Vol. 13, H. 3. pp. 302-313. Makowska, Z. and Blumer, T. and Duong, F. H. and La Monica, N. and Kandimalla, E. R. and Heim, M. H.. (2013) Sequential induction of type I and II interferons mediates a long-lasting gene induction in the liver in response to a novel toll-like receptor 9 agonist. Journal of hepatology, Vol. 58, H. 4. pp. 743-749. Heim, M.. (2013) Reply to miR-122, IL28B genotype and the response to interferon in chronic hepatitis C virus infection. Nature reviews. Immunology, Vol. 13, H. 12. p. 902. 2012Hagiwara, Asami and Cornu, Marion and Cybulski, Nadine and Polak, Pazit and Betz, Charles and Trapani, Francesca and Terracciano, Luigi and Heim, Markus H. and Rüegg, Markus A. and Hall, Michael N.. (2012) Hepatic mTORC2 activates glycolysis and lipogenesis through akt, glucokinase, and SREBP1c. Cell Metabolism, 15 (5). pp. 725-738. Patin, E. and Kutalik, Z. and Guergnon, J. and Bibert, S. and Nalpas, B. and Jouanguy, E. and Munteanu, M. and Bousquet, L. and Argiro, L. and Halfon, P. and Boland, A. and Mullhaupt, B. and Semela, D. and Dufour, J. F. and Heim, M. H. and Moradpour, D. and Cerny, A. and Malinverni, R. and Hirsch, H. and Martinetti, G. and Suppiah, V. and Stewart, G. and Booth, D. R. and George, J. and Casanova, J. L. and Brechot, C. and Rice, C. M. and Talal, A. H. and Jacobson, I. M. and Bourliere, M. and Theodorou, I. and Poynard, T. and Negro, F. and Pol, S. and Bochud, P. Y. and Abel, L.. (2012) Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. Gastroenterology, Vol. 143, H. 5 , S. 1244-1252.e12. Makowska, Z. and Heim, M. H.. (2012) Interferon signaling in the liver during hepatitis C virus infection. Cytokine, Vol. 59, H. 3. pp. 460-466. Larrey, D. and Lohse, A. W. and de Ledinghen, V. and Trepo, C. and Gerlach, T. and Zarski, J. P. and Tran, A. and Mathurin, P. and Thimme, R. and Arasteh, K. and Trautwein, C. and Cerny, A. and Dikopoulos, N. and Schuchmann, M. and Heim, M. H. and Gerken, G. and Stern, J. O. and Wu, K. and Abdallah, N. and Girlich, B. and Scherer, J. and Berger, F. and Marquis, M. and Kukolj, G. and Bocher, W. and Steffgen, J.. (2012) Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin. Journal of hepatology, Vol. 57, H. 1. pp. 39-46. Lange, C. M. and Kutalik, Z. and Morikawa, K. and Bibert, S. and Cerny, A. and Dollenmaier, G. and Dufour, J. F. and Gerlach, T. J. and Heim, M. H. and Malinverni, R. and Mullhaupt, B. and Negro, F. and Moradpour, D. and Bochud, P. Y.. (2012) Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy. Hepatology, Vol. 55, H. 4. pp. 1038-1047. Dill, M. T. and Rothweiler, S. and Djonov, V. and Hlushchuk, R. and Tornillo, L. and Terracciano, L. and Meili-Butz, S. and Radtke, F. and Heim, M. H. and Semela, D.. (2012) Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice. Gastroenterology, Vol. 142, H. 4 , S. 967-977.e2. Friedbichler, K. and Themanns, M. and Mueller, K. M. and Schlederer, M. and Kornfeld, J. W. and Terracciano, L. M. and Kozlov, A. V. and Haindl, S. and Kenner, L. and Kolbe, T. and Mueller, M. and Snibson, K. J. and Heim, M. H. and Moriggl, R.. (2012) Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer. Hepatology, Vol. 55, H. 3. pp. 941-952. Lange, C. M. and Bibert, S. and Kutalik, Z. and Burgisser, P. and Cerny, A. and Dufour, J. F. and Geier, A. and Gerlach, T. J. and Heim, M. H. and Malinverni, R. and Negro, F. and Regenass, S. and Badenhoop, K. and Bojunga, J. and Sarrazin, C. and Zeuzem, S. and Muller, T. and Berg, T. and Bochud, P. Y. and Moradpour, D.. (2012) A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C. PLoS one, Vol. 7, H. 7 , e40159. Kuske, L. and Mensen, A. and Mullhaupt, B. and Negro, F. and Semela, D. and Moradpour, D. and Male, P. J. and Heim, M. H. and Malinverni, R. and Cerny, A. and Dufour, J. F.. (2012) Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma. Swiss medical weekly, Vol. 142 , w13651. Heim, M. H.. (2012) Interferons and hepatitis C virus. Swiss medical weekly, Vol. 142 , w13586. Garaigorta, U. and Heim, M. H. and Boyd, B. and Wieland, S. and Chisari, F. V.. (2012) Hepatitis C virus (HCV) induces formation of stress granules whose proteins regulate HCV RNA replication and virus assembly and egress. Journal of virology, Vol. 86, H. 20. pp. 11043-11056. Bochud, P. Y. and Bibert, S. and Kutalik, Z. and Patin, E. and Guergnon, J. and Nalpas, B. and Goossens, N. and Kuske, L. and Mullhaupt, B. and Gerlach, T. and Heim, M. H. and Moradpour, D. and Cerny, A. and Malinverni, R. and Regenass, S. and Dollenmaier, G. and Hirsch, H. and Martinetti, G. and Gorgiewski, M. and Bourliere, M. and Poynard, T. and Theodorou, I. and Abel, L. and Pol, S. and Dufour, J. F. and Negro, F.. (2012) IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes. Hepatology, Vol. 55, H. 2. pp. 384-394. Stickel, F. and Helbling, B. and Heim, M. and Geier, A. and Hirschi, C. and Terziroli, B. and Wehr, K. and De Gottardi, A. and Negro, F. and Gerlach, T.. (2012) Critical review of the use of erythropoietin in the treatment of anaemia during therapy for chronic hepatitis C. Journal of viral hepatitis, Vol. 19, H. 2. pp. 77-87. Dill, M. T. and Makowska, Z. and Duong, F. H. and Merkofer, F. and Filipowicz, M. and Baumert, T. F. and Tornillo, L. and Terracciano, L. and Heim, M. H.. (2012) Interferon-gamma-stimulated genes, but not USP18, are expressed in livers of patients with acute hepatitis C. Gastroenterology, Vol. 143, H. 3 , S. 777-786.e6. 2011Trajkovski, Mirko and Hausser, Jean and Soutschek, Jürgen and Bhat, Bal and Akin, Akinc and Zavolan, Mihaela and Heim, Markus H. and Stoffel, Markus. (2011) MicroRNAs 103 and 107 regulate insulin sensitivity. Nature, Vol. 474, H. 7353. pp. 649-653. Semela, David and Heim, Markus. (2011) Hepatozelluläres Karzinom. Therapeutische Umschau, Bd. 68, H. 4. pp. 213-217. Müllhaupt, Beat and Durand, Francois and Roskams, Tanja and Dutkowski, Philipp and Heim, Markus. (2011) Is tumor biopsy necessary? Liver transplantation, Vol. 17, Suppl. 2 , S. S14-S25. Cai, Tao and Dufour, Jean-François and Muellhaupt, Beat and Gerlach, Tilman and Heim, Markus and Moradpour, Darius and Cerny, Andreas and Malinverni, Raffaele and Kaddai, Vincent and Bochud, Murielle and Negro, Francesco and Bochud, Pierre-Yves and Swiss Hepatitis C. Cohort Study Group, . (2011) Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis. Journal of hepatology, Vol. 55, H. 3. pp. 529-535. Makowska, Z. and Duong, F. H. and Trincucci, G. and Tough, D. F. and Heim, M. H.. (2011) Interferon-β and interferon-λ signaling is not affected by interferon-induced refractoriness to interferon-α in vivo. Hepatology, Vol. 53, No. 4. pp. 1154-1163. Zeuzem, S. and Asselah, T. and Angus, P. and Zarski, J. P. and Larrey, D. and Mullhaupt, B. and Gane, E. and Schuchmann, M. and Lohse, A. and Pol, S. and Bronowicki, J. P. and Roberts, S. and Arasteh, K. and Zoulim, F. and Heim, M. and Stern, J. O. and Kukolj, G. and Nehmiz, G. and Haefner, C. and Boecher, W. O.. (2011) Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection. Gastroenterology, Vol. 141, H. 6. pp. 2047-2055. Mueller, Kristina M. and Kornfeld, Jan-Wilhelm and Friedbichler, Katrin and Blaas, Leander and Egger, Gerda and Esterbauer, Harald and Hasselblatt, Peter and Schlederer, Michaela and Haindl, Susanne and Wagner, Kay-Uwe and Engblom, David and Haemmerle, Guenter and Kratky, Dagmar and Sexl, Veronika and Kenner, Lukas and Kozlov, Andrey V. and Terracciano, Luigi and Zechner, Rudolf and Schuetz, Guenther and Casanova, Emilio and Pospisilik, J. Andrew and Heim, Markus H. and Moriggl, Richard. (2011) Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice. Hepatology, Vol. 54, H. 4. pp. 1398-1409. Semela, D. and Heim, M.. (2011) Hepatozellulares Karzinom. Therapeutische Umschau, Vol. 68, H. 4. pp. 213-217. 2010Dill, M. T. and Duong, F. H. and Vogt, J. E. and Bibert, S. and Bochud, P. Y. and Terracciano, L. and Papassotiropoulos, A. and Roth, V. and Heim, M. H.. (2010) Interferon-Induced Gene Expression Is a Stronger Predictor of Treatment Response than IL28B Genotype in Patients with Hepatitis C. Gastroenterology, Vol. 140, H. 3 , S. 1021–1031. Gonvers, Jean-Jacques and Heim, Markus H. and Cavassini, Matthias and Müllhaupt, Beat and Genné, Daniel and Bernasconi, Enos and Borovicka, Jan and Cerny, Andreas and Chave, Jean-Philippe and Chuard, Christian and Dufour, François and Dutoit, Valérie and Malinverni, Raffaelle and Monnat, Martine and Negro, Francesco and Troilliet, Nicolas and Oneta, Carl. (2010) Treatment of hepatitis C in HCV mono-infected and in HIV-HCV co-infected patients : an open-labelled comparison study. Swiss Medical Weekly, Vol. 140 , w13055. Sarrazin, C. and Berg, T. and Ross, R. S. and Schirmacher, P. and Wedemeyer, H. and Neumann, U. and Schmidt, H. H. and Spengler, U. and Wirth, S. and Kessler, H. H. and Peck-Radosavljevic, M. and Ferenci, P. and Vogel, W. and Moradpour, D. and Heim, M. and Cornberg, M. and Protzer, U. and Manns, M. P. and Fleig, W. E. and Dollinger, M. M. and Zeuzem, S.. (2010) [Prophylaxis, diagnosis and therapy of hepatitis C virus (HCV) infection: the German guidelines on the management of HCV infection]. Zeitschrift für Gastroenterologie, Vol. 48, H. 2. pp. 289-351. Duong, Francois H. T. and Christen, Verena and Lin, Shanshan and Heim, Markus H.. (2010) Hepatitis C virus-induced up-regulation of protein phosphatase 2A inhibits histone modification and DNA damage repair. Hepatology, Vol. 51, No. 3. pp. 741-751. Sgier, C. and Müllhaupt, B. and Gerlach, T. and Moradpour, D. and Negro, F. and Malé, P. J. and Heim, M. H. and Malinverni, R. and Cerny, A. and Dufour, J.-F.. (2010) Effect of antiviral therapy on circulating cytokeratin-18 fragments in patients with chronic hepatitis C. Journal of viral hepatitis, Vol. 17, H. 12. pp. 845-850. Dufour, Jean-François and Hoppe, Hanno and Heim, Markus H. and Helbling, Beat and Maurhofer, Olivier and Szucs-Farkas, Zsolt and Kickuth, Ralph and Borner, Markus and Candinas, Daniel and Saar, Bettina. (2010) Continuous administration of sorafenib in combination with transarterial chemoembolization in patients with hepatocellular carcinoma : results of a phase I study. The oncologist, Vol. 15, H. 11. pp. 1198-1204. Ripoli, Maria and D'Aprile, Annamaria and Quarato, Giovanni and Sarasin-Filipowicz, Magdalena and Gouttenoire, Jérôme and Scrima, Rosella and Cela, Olga and Boffoli, Domenico and Heim, Markus H. and Moradpour, Darius and Capitanio, Nazzareno and Piccoli, Claudia. (2010) Hepatitis C virus-linked mitochondrial dysfunction promotes hypoxia-inducible factor 1 alpha-mediated glycolytic adaptation. Journal of virology, Vol. 84, H. 1. pp. 647-660. Filipowicz, Magdalena and Bernsmeier, Christine and Terracciano, Luigi and Duong, Francois H. T. and Heim, Markus H.. (2010) S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse. PLoS one, Vol. 5, H. 11 , e15492. Kim, Min Jeong and Heim, Markus and Mayr, Michael. (2010) Effect of corticosteroids during ongoing drug exposure in pantoprazole-induced interstitial nephritis. Nephrology Dialysis Transplantation, Vol. 25, H. 5. pp. 1716-1719. Rauch, Andri and Kutalik, Zoltán and Descombes, Patrick and Cai, Tao and Di Iulio, Julia and Mueller, Tobias and Bochud, Murielle and Battegay, Manuel and Bernasconi, Enos and Borovicka, Jan and Colombo, Sara and Cerny, Andreas and Dufour, Jean-François and Furrer, Hansjakob and Günthard Huldrych, F. and Heim, Markus and Hirschel, Bernard and Malinverni, Raffaele and Moradpour, Darius and Müllhaupt, Beat and Witteck, Andrea and Beckmann, Jacques S. and Berg, Thomas and Bergmann, Sven and Negro, Francesco and Telenti, Amalio and Bochud, Pierre-Yves and Swiss Hepatitis C. Cohort Study, and Swiss HIV Cohort Study, . (2010) Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure : a genome-wide association study. Gastroenterology, Vol. 138, H. 4 , S. 1338-1345, 1345.e1-7. Bellecave, Pantxika and Sarasin-Filipowicz, Magdalena and Donzé, Olivier and Kennel, Audrey and Gouttenoire, Jérôme and Meylan, Etienne and Terracciano, Luigi and Tschopp, Jürg and Sarrazin, Christoph and Berg, Thomas and Moradpour, Darius and Heim, Markus H.. (2010) Cleavage of mitochondrial antiviral signaling protein in the liver of patients with chronic hepatitis C correlates with a reduced activation of the endogenous interferon system. Hepatology, Vol. 51, H. 4. pp. 1127-1136. Bareiss, D. and Semela, D. and Heim, M. and Terracciano, L. and Hunziker, S.. (2010) [44 year old gardener with lower back pain, myalgia and fever]. Schweizerische Rundschau für Medizin PRAXIS, Vol. 99, H. 2. pp. 127-132. 2009Tchorz, Jan S. and Kinter, Jochen and Müller, Matthias and Tornillo, Luigi and Heim, Markus H. and Bettler, Bernhard. (2009) Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice. Hepatology : official journal of the American Association for the Study of Liver Diseases, Vol. 50, No. 3. pp. 871-879. Bernsmeier, Christine and Heim, Markus H.. (2009) Insulin resistance in chronic hepatitis C : mechanisms and clinical relevance. Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology, Vol. 139. pp. 678-684. Sarasin-Filipowicz, Magdalena and Wang, Xueya and Yan, Ming and Duong, Francois H. T. and Poli, Valeria and Hilton, Douglas J. and Zhang, Dong-Er and Heim, Markus H.. (2009) Alpha interferon induces long-lasting refractoriness of JAK-STAT signaling in the mouse liver through induction of USP18/UBP43. Molecular and cellular biology : MCB : a publication of the American Society for Microbiology, Vol. 29. pp. 4841-4851. Bochud, Pierre-Yves and Cai, Tao and Overbeck, Kathrin and Bochud, Murielle and Dufour, Jean-François and Müllhaupt, Beat and Borovicka, Jan and Heim, Markus and Moradpour, Darius and Cerny, Andreas and Malinverni, Raffaele and Francioli, Patrick and Negro, Francesco. (2009) Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C. Journal of hepatology : journal of the European Association for the Study of the Liver, Vol. 51. pp. 655-666. Sarasin-Filipowicz, M. and Krol, J. and Markiewicz, I. and Heim, M. H. and Filipowicz, W.. (2009) Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nature medicine, Vol. 15. pp. 31-33. Dinges, S. and Morard, I. and Heim, M. and Dufour, J.-F. and Müllhaupt, B. and Giostra, E. and Clavien, P.-A. and Mentha, G. and Negro, F.. (2009) Pegylated interferon-alpha2a/ribavirin treatment of recurrent hepatitis C after liver transplantation. Transplant infectious disease : an official journal of the Transplantation Society, Vol. 11. pp. 33-39. 2008Khanlari, B. and Bodmer, M. and Terracciano, L. and Heim, M. H. and Fluckiger, U. and Weisser, M.. (2008) Hepatitis with fibrin-ring granulomas. Infection, 36 (4). pp. 381-383. Giovanoli, O. and Heim, M. and Terracciano, L. and Bongartz, G. and Ledermann, H. P.. (2008) MRI of hepatic adenomatosis: initial observations with gadoxetic acid contrast agent in three patients. American journal of roentgenology, Vol. 190 , W290-293. Ciuffreda, D. and Comte, D. and Cavassini, M. and Giostra, E. and Bühler, L. and Perruchoud, M. and Heim, M. H. and Battegay, M. and Genné, D. and Mulhaupt, B. and Malinverni, R. and Oneta, C. and Bernasconi, E. and Monnat, M. and Cerny, A. and Chuard, C. and Borovicka, J. and Mentha, G. and Pascual, M. and Gonvers, J. J. and Pantaleo, G. and Dutoit, V.. 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