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2017

Vizeli, Patrick and Schmid, Yasmin and Prestin, Katharina and Meyer Zu Schwabedissen, Henriette E. and Liechti, Matthias E.. (2017) Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects. European Neuropsychopharmacology, 27 (3). pp. 232-238.

Dolder, Patrick C. and Grünblatt, Edna and Müller, Felix and Borgwardt, Stefan J. and Liechti, Matthias E.. (2017) A Single Dose of LSD Does Not Alter Gene Expression of the Serotonin 2A Receptor Gene (HTR2A) or Early Growth Response Genes (EGR1-3) in Healthy Subjects. Frontiers in Pharmacology, 8. p. 423.

Luethi, Dino and Liechti, Matthias E. and Krähenbühl, Stephan. (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology, 387. pp. 57-66.

Schmidt, André and Müller, Felix and Dolder, Patrick C. and Schmid, Yasmin and Zanchi, Davide and Liechti, Matthias E. and Borgwardt, Stefan. (2017) Comparative Effects of Methylphenidate, Modafinil, and MDMA on Response Inhibition Neural Networks in Healthy Subjects. International Journal of Neuropsychopharmacology, 20 (9). pp. 712-720.

Liechti, Matthias E.. (2017) Modern Clinical Research on LSD. Neuropsychopharmacology, 42 (11). pp. 2114-2127.

Vizeli, Patrick and Liechti, Matthias E.. (2017) Safety pharmacology of acute MDMA administration in healthy subjects. Journal of Psychopharmacology, 31 (5). pp. 576-588.

Mueller, F. and Lenz, C. and Dolder, P. C. and Harder, S. and Schmid, Y. and Lang, U. E. and Liechti, M. E. and Borgwardt, S.. (2017) Acute effects of LSD on amygdala activity during processing of fearful stimuli in healthy subjects. Translational Psychiatry, 7 (4). e1084.

Liakoni, Evangelia and Müller, Sabine and Stoller, Adrian and Ricklin, Meret and Liechti, Matthias E. and Exadaktylos, Aristomenis K.. (2017) Presentations to an urban emergency department in Bern, Switzerland associated with acute recreational drug toxicity. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 25 (1). p. 26.

Dolder, Patrick C. and Schmid, Yasmin and Steuer, Andrea E. and Kraemer, Thomas and Rentsch, Katharina M. and Hammann, Felix and Liechti, Matthias E.. (2017) Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects. Clinical Pharmacokinetics. pp. 1219-1230.

Kuypers, Kim Pc and Dolder, Patrick C. and Ramaekers, Johannes G. and Liechti, Matthias E.. (2017) Multifaceted empathy of healthy volunteers after single doses of MDMA: A pooled sample of placebo-controlled studies. Journal of Psychopharmacology, 31 (5). pp. 589-598.

Luethi, Dino and Kaeser, Philine J. and Brandt, Simon D. and Krähenbühl, Stephan and Hoener, Marius C. and Liechti, Matthias E.. (2017) Pharmacological profile of methylphenidate-based designer drugs. Neuropharmacology, 17. 0028.

Luethi, Dino and Kolaczynska, Karolina E. and Docci, Luca and Krähenbühl, Stephan and Hoener, Marius C. and Liechti, Matthias E.. (2017) Pharmacological profile of mephedrone analogs and related new psychoactive substances. Neuropharmacology, 17. 0028.

Luethi, Dino and Trachsel, Daniel and Hoener, Marius C. and Liechti, Matthias E.. (2017) Monoamine receptor interaction profiles of 4-thio-substituted phenethylamines (2C-T drugs). Neuropharmacology, 17. 0028.

2016

Strajhar, Petra and Schmid, Y. and Liakoni, E. and Dolder, P. C. and Rentsch, K. M. and Kratschmar, Denise V. and Odermatt, Alex and Liechti, Matthias E.. (2016) Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects. Journal of Neuroendocrinology, 28 (3). p. 12374.

Steuer, Andrea E. and Schmidhauser, Corina and Tingelhoff, Eva H. and Schmid, Yasmin and Rickli, Anna and Kraemer, Thomas and Liechti, Matthias E.. (2016) Impact of cytochrome P450 2D6 function on the chiral blood plasma pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its phase I and II metabolites in humans. PLoS one, 11 (3). e0150955.

Simmler, Linda D. and Buchy, Danièle and Chaboz, Sylvie and Hoener, Marius C. and Liechti, Matthias E.. (2016) In vitro characterization of psychoactive substances at rat, mouse, and human trace amine-associated receptor 1. Journal of pharmacology and experimental therapeutics, 357 (1). pp. 134-144.

Mueller, F. and Lenz, C. and Steiner, M. and Dolder, P. C. and Walter, M. and Lang, U. E. and Liechti, M. E. and Borgwardt, S.. (2016) Neuroimaging in moderate MDMA use: a systematic review. Neuroscience and Biobehavioral Reviews, 62 (8). pp. 21-34.

Madry, Milena M. and Steuer, Andrea E. and Hysek, Cédric M. and Liechti, Matthias E. and Baumgartner, Markus R. and Kraemer, Thomas. (2016) Evaluation of drug incorporation into hair segments and nails by enantiomeric analysis following controlled single MDMA intakes. Analytical and bioanalytical chemistry, 408 (2). pp. 545-556.

Poetzsch, Michael and Steuer, Andrea E. and Hysek, Cédric M. and Liechti, Matthias E. and Kraemer, Thomas. (2016) Development of a high-speed MALDI-triple quadrupole mass spectrometric method for the determination of 3,4-methylenedioxymethamphetamine (MDMA) in oral fluid. Drug testing and analysis, 8 (2). pp. 235-240.

Liakoni, Evangelia and Dolder, Patrick C. and Rentsch, Katharina M. and Liechti, Matthias E.. (2016) Presentations due to acute toxicity of psychoactive substances in an urban emergency department in Switzerland: a case series. BMC pharmacology & toxicology. p. 7.

Dolder, Patrick C. and Schmid, Yasmin and Müller, Felix and Borgwardt, Stefan and Liechti, Matthias E.. (2016) LSD Acutely Impairs Fear Recognition and Enhances Emotional Empathy and Sociality. Neuropsychopharmacology, 41 (11). pp. 2638-2646.

Schmid, Yasmin and Vizeli, Patrick and Hysek, Cédric M. and Prestin, Katharina and Meyer Zu Schwabedissen, Henriette E. and Liechti, Matthias E.. (2016) CYP2D6 function moderates the pharmacokinetics and pharmacodynamics of 3,4-methylene-dioxymethamphetamine in a controlled study in healthy individuals. Pharmacogenetics and Genomics, 26 (8). pp. 397-401.

Vallersnes, Odd Martin and Dines, Alison M. and Wood, David M. and Yates, Christopher and Heyerdahl, Fridtjof and Hovda, Knut Erik and Giraudon, Isabelle and Euro-DEN Research Group, and Dargan, Paul I.. (2016) Psychosis associated with acute recreational drug toxicity: a European case series. BMC Psychiatry. p. 8.

Liakoni, Evangelia and Walther, Fabio and Nickel, Christian H. and Liechti, Matthias E.. (2016) Presentations to an urban emergency department in Switzerland due to acute γ-hydroxybutyrate toxicity. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 24. p. 107.

Rickli, Anna and Moning, Olivier D. and Hoener, Marius C. and Liechti, Matthias E.. (2016) Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens. European Neuropsychopharmacology, 26 (8). pp. 1327-1337.

Dolder, Patrick C. and Holze, Friederike and Liakoni, Evangelia and Harder, Samuel and Schmid, Yasmin and Liechti, Matthias E.. (2016) Alcohol acutely enhances decoding of positive emotions and emotional concern for positive stimuli and facilitates the viewing of sexual images. Psychopharmacology, 234 (1). pp. 41-51.

Liechti, Matthias E. and Dolder, Patrick C. and Schmid, Yasmin. (2016) Alterations of consciousness and mystical-type experiences after acute LSD in humans. Psychopharmacology, 234 (9-10). pp. 1499-1510.

Simmler, Linda D. and Liechti, Matthias E.. (2016) Interactions of Cathinone NPS with Human Transporters and Receptors in Transfected Cells. Current Topics in Behavioral Neurosciences. pp. 49-72.

2015

Schmid, Yasmin and Rickli, Anna and Schaffner, Antonia and Duthaler, Urs and Grouzmann, Eric and Hysek, Cédric M. and Liechti, Matthias E.. (2015) Interactions between bupropion and 3,4-methylenedioxymethamphetamine in healthy subjects. Journal of pharmacology and experimental therapeutics, 353 (1). pp. 102-111.

Schmid, Yasmin and Enzler, Florian and Gasser, Peter and Grouzmann, Eric and Preller, Katrin H. and Vollenweider, Franz X. and Brenneisen, Rudolf and Müller, Felix and Borgwardt, Stefan and Liechti, Matthias E.. (2015) Acute effects of lysergic acid diethylamide in healthy subjects. Biological psychiatry, 78 (8). pp. 544-553.

Dolder, Patrick C. and Schmid, Yasmin and Haschke, Manuel and Rentsch, Katharina M. and Liechti, Matthias E.. (2015) Pharmacokinetics and concentration-effect relationship of oral LSD in humans. International journal of neuropsychopharmacology, 19 (1). pyv072.

Schmid, Yasmin and Hysek, Cédric M. and Preller, Katrin H. and Bosch, Oliver G. and Bilderbeck, Amy C. and Rogers, Robert D. and Quednow, Boris B. and Liechti, Matthias E.. (2015) Effects of methylphenidate and MDMA on appraisal of erotic stimuli and intimate relationships. European neuropsychopharmacology, 25 (1). pp. 17-25.

Bigler, Marc B. and Egli, Simon B. and Hysek, Cédric M. and Hoenger, Gideon and Schmied, Laurent and Baldin, Fabian S. and Marquardsen, Florian A. and Recher, Mike and Liechti, Matthias E. and Hess, Christoph and Berger, Christoph T.. (2015) Stress-induced in vivo recruitment of human cytotoxic natural killer cells favors subsets with distinct receptor profiles and associates with increased epinephrine levels. PLoS one, 10 (12). e0145635.

Liakoni, Evangelia and Dolder, Patrick C. and Rentsch, Katharina and Liechti, Matthias E.. (2015) Acute health problems due to recreational drug use in patients presenting to an urban emergency department in Switzerland. Swiss medical weekly, 145. w14166.

Steuer, Andrea E. and Schmidhauser, Corina and Schmid, Yasmin and Rickli, Anna and Liechti, Matthias E. and Kraemer, Thomas. (2015) Chiral plasma pharmacokinetics of 3,4-methylenedioxymethamphetamine and its phase I and II metabolites following controlled administration to humans. Drug metabolism and disposition, 43 (12). pp. 1864-1871.

Steuer, Andrea E. and Schmidhauser, Corina and Liechti, Matthias E. and Kraemer, Thomas. (2015) Development and validation of an LC-MS/MS method after chiral derivatization for the simultaneous stereoselective determination of methylenedioxy-methamphetamine (MDMA) and its phase I and II metabolites in human blood plasma. Drug testing and analysis, 7 (7). pp. 592-602.

Liechti, Matthias E.. (2015) Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signalling. Swiss medical weekly, 145. w14043.

Dolder, Patrick C. and Liechti, Matthias E. and Rentsch, Katharina M.. (2015) Development and validation of a rapid turboflow LC-MS/MS method for the quantification of LSD and 2-oxo-3-hydroxy LSD in serum and urine samples of emergency toxicological cases. Analytical and bioanalytical chemistry, 407 (6). pp. 1577-1584.

Liechti, Matthias E. and Quednow, Boris B. and Liakoni, Evangelia and Dornbierer, Dario and von Rotz, Robin and Salomé Gachet, M. and Gertsch, Jürg and Seifritz, Erich and Bosch, Oliver G.. (2015) Pharmacokinetics and pharmacodynamics of γ-hydroxybutyrate in healthy subjects. British Journal of Clinical Pharmacology, 81 (5). pp. 980-988.

Maier, Larissa J. and Liakoni, Evangelia and Schildmann, Jan and Schaub, Michael P. and Liechti, Matthias E.. (2015) Swiss University Students' Attitudes toward Pharmacological Cognitive Enhancement. PLoS One, 10 (12). e0144402.

Liakoni, Evangelia and Schaub, Michael P. and Maier, Larissa J. and Glauser, Gaëlle-Vanessa and Liechti, Matthias E.. (2015) The Use of Prescription Drugs, Recreational Drugs, and "Soft Enhancers" for Cognitive Enhancement among Swiss Secondary School Students. PLoS One, 10 (10). e0141289.

Rickli, Anna and Luethi, Dino and Reinisch, Julian and Buchy, Danièle and Hoener, Marius C. and Liechti, Matthias E.. (2015) Receptor interaction profiles of novel N-2-methoxybenzyl (NBOMe) derivatives of 2,5-dimethoxy-substituted phenethylamines (2C drugs). Neuropharmacology, 99. pp. 546-553.

Rickli, Anna and Kopf, Simone and Hoener, Marius C. and Liechti, Matthias E.. (2015) Pharmacological profile of novel psychoactive benzofurans. British Journal of Pharmacology, 172 (13). pp. 3412-3425.

Rickli, Anna and Hoener, Marius C. and Liechti, Matthias E.. (2015) Monoamine transporter and receptor interaction profiles of novel psychoactive substances: para-halogenated amphetamines and pyrovalerone cathinones. European Neuropsychopharmacology, 25 (3). pp. 365-376.

2014

Seibert, Julia and Hysek, Cédric M. and Penno, Carlos A. and Schmid, Yasmin and Kratschmar, Denise V. and Liechti, Matthias E. and Odermatt, Alex. (2014) Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects. Neuroendocrinology, 100 (1). pp. 17-25.

Simmler, L. D. and Rickli, A. and Hoener, M. C. and Liechti, M. E.. (2014) Monoamine transporter and receptor interaction profiles of a new series of designer cathinones. Neuropharmacology, Vol. 79. pp. 152-160.

Hysek, C. M. and Schmid, Y. and Simmler, L. D. and Domes, G. and Heinrichs, M. and Eisenegger, C. and Preller, K. H. and Quednow, B. B. and Liechti, M. E.. (2014) MDMA enhances emotional empathy and prosocial behavior. Social cognitive and affective neuroscience, 9 (11). pp. 1645-1652.

Hysek, C. M. and Simmler, L. D. and Schillinger, N. and Meyer, N. and Schmid, Y. and Donzelli, M. and Grouzmann, E. and Liechti, M. E.. (2014) Pharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination. International journal of neuropsychopharmacology, 17 (3). pp. 371-381.

Schmid, Yasmin and Hysek, Cédric M. and Simmler, Linda D. and Crockett, Molly J. and Quednow, Boris B. and Liechti, Matthias E.. (2014) Differential effects of MDMA and methylphenidate on social cognition. Journal of psychopharmacology, 28 (9). pp. 847-856.

Liechti, Matthias E.. (2014) Effects of MDMA on body temperature in humans. Temperature, 1 (3). pp. 179-187.

Bodmer, Michael and Enzler, Florian and Liakoni, Evangelia and Bruggisser, Marcel and Liechti, Matthias E.. (2014) Acute cocaine-related health problems in patients presenting to an urban emergency department in Switzerland: a case series. BMC Research Notes, 7. p. 173.

Simmler, Linda D. and Rickli, Anna and Schramm, York and Hoener, Marius C. and Liechti, Matthias E.. (2014) Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives. Biochemical Pharmacology, 88 (2). pp. 237-244.

2013

Maier, L. J. and Liechti, M. E. and Herzig, F. and Schaub, M. P.. (2013) To dope or not to dope: neuroenhancement with prescription drugs and drugs of abuse among Swiss university students. PLoS one, Vol. 8, H. 11 , e77967.

Hysek, C. M. and Schmid, Y. and Rickli, A. and Liechti, M. E.. (2013) Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans : lost in translation. British journal of pharmacology, 170 (6). pp. 1273-1275.

Hysek, C. M. and Fink, A. E. and Simmler, L. D. and Donzelli, M. and Grouzmann, E. and Liechti, M. E.. (2013) a-Adrenergic receptors contribute to the acute effects of MDMA in humans. Journal of clinical psychopharmacology, Vol. 33, H. 5. pp. 658-666.

Maier, L. J. and Liechti, M. E. and Schaub, M.. (2013) Neuroenhancement: auch an Schweizer Universitäten? SuchtMagazin, Jg. 39, H. 3. pp. 21-24.

2012

Hysek, C. M. and Simmler, L. D. and Nicola, V. G. and Vischer, N. and Donzelli, M. and Krahenbuhl, S. and Grouzmann, E. and Huwyler, J. and Hoener, M. C. and Liechti, M. E.. (2012) Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study. PLoS one, Vol. 7, H. 5 , e36476.

Simmler, L. D. and Buser, T. A. and Donzelli, M. and Schramm, Y. and Dieu, L. H. and Huwyler, J. and Chaboz, S. and Hoener, M. C. and Liechti, M. E.. (2012) Pharmacological characterization of designer cathinones in vitro. British journal of pharmacology, Vol. 168, no. 2. pp. 458-470.

Derungs, A. and Schwaninger, A. E. and Mansella, G. and Bingisser, R. and Kraemer, T. and Liechti, M. E.. (2012) Symptoms, toxicities, and analytical results for a patient after smoking herbs containing the novel synthetic cannabinoid MAM-2201. Forensic toxicology, Vol. 31, H. 1. pp. 164-171.

Hysek, C. M. and Brugger, R. and Simmler, L. D. and Bruggisser, M. and Donzelli, M. and Grouzmann, E. and Hoener, M. C. and Liechti, M. E.. (2012) Effects of the α₂-adrenergic agonist clonidine on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine in healthy volunteers. Journal of pharmacology and experimental therapeutics, Vol. 340, H. 2. pp. 286-294.

Hysek, C. M. and Domes, G. and Liechti, M. E.. (2012) MDMA enhances "mind reading" of positive emotions and impairs "mind reading" of negative emotions. Psychopharmacology, Vol. 222, H. 2. pp. 293-302.

Hysek, C. M. and Liechti, M. E.. (2012) Effects of MDMA alone and after pretreatement with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex. Psychopharmacology, Vol. 224, no. 3. pp. 363-376.

Hysek, C. and Schmid, Y. and Rickli, A. and Simmler, L. D. and Donzelli, M. and Grouzmann, E. and Liechti, M. E.. (2012) Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans. British journal of pharmacology, Vol. 166, H. 8. pp. 2277-2288.

Hysek, Cédric M. and Liechti, Matthias E.. (2012) Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex. Psychopharmacology, 224 (3). pp. 363-376.

2011

Hysek, C. M. and Simmler, L. D. and Ineichen, M. and Grouzmann, E. and Hoener, M. C. and Brenneisen, R. and Huwyler, J. and Liechti, M. E.. (2011) The Norepinephrine Transporter Inhibitor Reboxetine Reduces Stimulant Effects of MDMA ("Ecstasy") in Humans. Clinical pharmacology and therapeutics, Vol. 90, H. 2. pp. 246-255.

Derungs, A. and Schietzel, S. and Meyer, M. R. and Maurer, H. H. and Krahenbuhl, S. and Liechti, M. E.. (2011) Sympathomimetic toxicity in a case of analytically confirmed recreational use of naphyrone (naphthylpyrovalerone). Clinical toxicology, Vol. 49, H. 7. pp. 691-693.

Bruggisser, Marcel and Bodmer, Michael and Liechti, Matthias E.. (2011) Severe toxicity due to injected but not oral or nasal abuse of methylphenidate tablets. Swiss medical weekly, Vol. 141 , w13267.

Simmler, L. D. and Hysek, C. M. and Liechti, M. E.. (2011) Sex differences in the effects of MDMA (ecstasy) on plasma copeptin in healthy subjects. Journal of clinical endocrinology and metabolism, Vol. 96, H. 9. pp. 2844-2850.

D'Souza, M. S. and Liechti, M. E. and Ramirez-Nino, A. M. and Kuczenski, R. and Markou, A.. (2011) The metabotropic glutamate 2/3 receptor agonist LY379268 blocked nicotine-induced increases in nucleus accumbens shell dopamine only in the presence of a nicotine-associated context in rats. Neuropsychopharmacology, 36 (10). pp. 2111-2124.

2010

Hysek, C. M. and Vollenweider, F. X. and Liechti, M. E.. (2010) Effects of a beta-blocker on the cardiovascular response to MDMA (Ecstasy). Emergency medicine journal, Vol. 27, H. 8. pp. 586-589.

Bruggisser, Marcel and Ceschi, Alessandro and Bodmer, Michael and Wilks, Martin F. and Kupferschmidt, Hugo and Liechti, Matthias E.. (2010) Retrospective analysis of stimulant abuse cases reported to the Swiss Toxicological Information Centre during 1997-2009. Swiss medical weekly, Vol. 140 , w13115.

2009

Fiegler, K. and Liechti, M. E. and Bodmer, M. and Bruggisser, M.. (2009) Akzidentelle Lithiumintoxikation = Intoxication with lithium. Schweizerische Rundschau für Medizin Praxis, Jg. 98, Nr. 13. pp. 685-691.

Bodmer, M. and Haschke, M. and Bravo, Rätz and Liechti, M. E.. (2009) Nierenversagen und hämolytische Anämie = Acute renal failure due to rifampicine. Schweizerische Rundschau für Medizin Praxis, Jg. 98, Nr. 4. pp. 179-185.

2008

Bodmer, M. and Christ, A. and Liechti, M. E.. (2008) Intoxikation mit einem unbekannten Sedativum = Intoxication with an unknown sedative substance. Schweizerische Rundschau für Medizin Praxis, Jg. 97, Nr. 15. pp. 820-825.

Liechti, Matthias E. and Markou, Athina. (2008) Role of the glutamatergic system in nicotine dependence : implications for the discovery and development of new pharmacological smoking cessation therapies. CNS drugs, Vol. 22, no. 9. pp. 705-724.

Liechti, Matthias E. and Markou, Athina. (2008) Role of the glutamatergic system in nicotine dependence : implications for the discovery and development of new pharmacological smoking cessation therapies. CNS drugs, Vol. 22, H. 9. pp. 705-724.