Items where Author is "Dehio, Christoph"

2017

Harms, Alexander and Segers, Francisca H. I. D. and Quebatte, Maxime and Mistl, Claudia and Manfredi, Pablo and Körner, Jonas and Chomel, Bruno B. and Kosoy, Michael and Maruyama, Soichi and Engel, Philipp and Dehio, Christoph. (2017) Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella. Genome biology and evolution, 9 (3). pp. 761-776.

Riba, Andrea and Emmenlauer, Mario and Chen, Amy and Sigoillot, Frederic and Cong, Feng and Dehio, Christoph and Jenkins, Jeremy and Zavolan, Mihaela. (2017) Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results. Cell Systems, 4 (2). pp. 182-193.e4.

Stanger, Frédéric V. and de Beer, Tjaart A. P. and Dranow, David M. and Schirmer, Tilman and Phan, Isabelle and Dehio, Christoph. (2017) The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure , 25 (1). pp. 203-211.

González-Prieto, Coral and Gabriel, Richard and Dehio, Christoph and Schmidt, Manfred and Llosa, Matxalen. (2017) The Conjugative Relaxase TrwC Promotes Integration of Foreign DNA in the Human Genome. Applied and Environmental Microbiology, 83 (12). e00207-17.

8 May 2016

Casanova, Alain and Low, Shyan H. and Emmenlauer, Mario and Conde-Alvarez, Raquel and Salcedo, Suzana P. and Gorvel, Jean-Pierre and Dehio, Christoph. (2016) Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells. Journal of Visualized Experiments (114). e54263.

2016

Andritschke, Daniel and Dilling, Sabrina and Emmenlauer, Mario and Welz, Tobias and Schmich, Fabian and Misselwitz, Benjamin and Rämö, Pauli and Rottner, Klemens and Kerkhoff, Eugen and Wada, Teiji and Penninger, Josef M. and Beerenwinkel, Niko and Horvath, Peter and Dehio, Christoph and Hardt, Wolf-Dietrich. (2016) A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. PLoS ONE, 11 (9). e0161965.

Harms, Alexander and Stanger, Frédéric Valentin and Dehio, Christoph. (2016) Biological Diversity and Molecular Plasticity of FIC Domain Proteins. Annual Reviews of Microbiology, 70. pp. 341-360.

Stanger, Frédéric V. and Harms, Alexander and Dehio, Christoph and Schirmer, Tilman. (2016) Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin. PLoS One, 11 (9). e0163654.

Stanger, Frédéric V. and Burmann, Björn M. and Harms, Alexander and Aragão, Hugo and Mazur, Adam and Sharpe, Timothy and Dehio, Christoph and Hiller, Sebastian and Schirmer, Tilman. (2016) Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proceedings of the National Academy of Sciences of the United States of America, 113 (5). E529-E537.

11 November 2015

Kreibich, Saskia and Emmenlauer, Mario and Fredlund, Jennifer and Rämö, Pauli and Münz, Christian and Dehio, Christoph and Enninga, Jost and Hardt, Wolf-Dietrich. (2015) Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1. Cell host & microbe, 18 (5). pp. 527-537.

21 October 2015

Schmich, Fabian and Szczurek, Ewa and Kreibich, Saskia and Dilling, Sabrina and Andritschke, Daniel and Casanova, Alain and Low, Shyan Huey and Eicher, Simone and Muntwiler, Simone and Emmenlauer, Mario and Rämo, Pauli and Conde-Alvarez, Raquel and von Mering, Christian and Hardt, Wolf-Dietrich and Dehio, Christoph and Beerenwinkel, Niko. (2015) Erratum to: gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens. Genome Biology, 16 (233). p. 1.

7 October 2015

Schmich, Fabian and Szczurek, Ewa and Kreibich, Saskia and Dilling, Sabrina and Andritschke, Daniel and Casanova, Alain and Low, Shyan Huey and Eicher, Simone and Muntwiler, Simone and Emmenlauer, Mario and Rämö, Pauli and Conde-Alvarez, Raquel and von Mering, Christian and Hardt, Wolf-Dietrich and Dehio, Christoph and Beerenwinkel, Niko. (2015) gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens. Genome Biology, 16 (220). pp. 1-12.

September 2015

Harms, Alexander and Stanger, Frédéric Valentin and Scheu, Patrick Daniel and de Jong, Imke Greet and Goepfert, Arnaud and Glatter, Timo and Gerdes, Kenn and Schirmer, Tilman and Dehio, Christoph. (2015) Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology. Cell reports, 12 (9). pp. 1497-1507.

April 2015

Siebourg-Polster, Juliane and Mudrak, Daria and Emmenlauer, Mario and Rämö, Pauli and Dehio, Christoph and Greber, Urs and Fröhlich, Holger and Beerenwinkel, Niko. (2015) NEMix: single-cell nested effects models for probabilistic pathway stimulation. PLoS Computational Biology, 11 (4). e1004078.

2015

Kühbacher, Andreas and Emmenlauer, Mario and Rämö, Pauli and Kafai, Natasha and Dehio, Christoph and Cossart, Pascale and Pizarro-Cerdá, Javier. (2015) Genome-Wide siRNA Screen Identifies Complementary Signaling Pathways Involved in Listeria Infection and Reveals Different Actin Nucleation Mechanisms during Listeria Cell Invasion and Actin Comet Tail Formation. mBio, 6 (3). e00598-15.

December 2014

Rämö, Pauli and Drewek, Anna and Arrieumerlou, Cécile and Beerenwinkel, Niko and Ben-Tekaya, Houchaïma and Cardel, Bettina and Casanova, Alain and Conde-Alvarez, Raquel and Cossart, Pascale and Csúcs, Gábor and Eicher, Simone and Emmenlauer, Mario and Greber, Urs and Hardt, Wolf-Dietrich and Helenius, Ari and Kasper, Christoph and Kaufmann, Andreas and Kreibich, Saskia and Kühbacher, Andreas and Kunszt, Peter and Low, Shyan Huey and Mercer, Jason and Mudrak, Daria and Muntwiler, Simone and Pelkmans, Lucas and Pizarro-Cerdá, Javier and Podvinec, Michael and Pujadas, Eva and Rinn, Bernd and Rouilly, Vincent and Schmich, Fabian and Siebourg-Polster, Juliane and Snijder, Berend and Stebler, Michael and Studer, Gabriel and Szczurek, Ewa and Truttmann, Matthias and von Mering, Christian and Vonderheit, Andreas and Yakimovich, Artur and Bühlmann, Peter and Dehio, Christoph. (2014) Simultaneous analysis of large-scale RNAi screens for pathogen entry. BMC Genomics, 15 (1). p. 1162.

2014

Okujava, Rusudan and Guye, Patrick and Lu, Yun-Yueh and Mistl, Claudia and Polus, Florine and Vayssier-Taussat, Muriel and Halin, Cornelia and Rolink, Antonius G. and Dehio, Christoph. (2014) A translocated effector required for bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors. PLoS Pathogens, Vol. 10, H. 6 , e1004187.

Pieles, Kathrin and Glatter, Timo and Harms, Alexander and Schmidt, Alexander and Dehio, Christoph. (2014) An experimental strategy for the identification of AMPylation targets from complex protein samples. Proteomics, 14 (9). pp. 1048-1052.

Siamer, Sabrina and Dehio, Christoph. (2014) New insights into the role of Bartonella effector proteins in pathogenesis. Current Opinion in Microbiology, Vol. 23C. pp. 80-85.

Stekhoven, Daniel J. and Omasits, Ulrich and Quebatte, Maxime and Dehio, Christoph and Ahrens, Christian H.. (2014) Proteome-wide identification of predominant subcellular protein localizations in a bacterial model organism. Journal of Proteomics , 99. pp. 123-137.

Franceschini, Andrea and Meier, Roger and Casanova, Alain and Kreibich, Saskia and Daga, Neha and Andritschke, Daniel and Dilling, Sabrina and Rämö, Pauli and Emmenlauer, Mario and Kaufmann, Andreas and Conde-Álvarez, Raquel and Low, Shyan Huey and Pelkmans, Lucas and Helenius, Ari and Hardt, Wolf-Dietrich and Dehio, Christoph and von Mering, Christian. (2014) Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens. Proceedings of the National Academy of Sciences, 111 (12). pp. 4548-4553.

Stanger, Frédéric V. and Dehio, Christoph and Schirmer, Tilman. (2014) Structure of the N-terminal gyrase B fragment in complex with ADP⋅Pi reveals rigid-body motion induced by ATP hydrolysis. PloS one, Vol. 9, H. 9 , e107289.

2013

Goepfert, Arnaud and Stanger, Frédéric V. and Dehio, Christoph and Schirmer, Tilman. (2013) Conserved inhibitory mechanism and competent ATP binding mode for adenylyltransferases with fic fold. PLoS one, Vol. 8, H. 5 , e64901.

Québatte, Maxime and Dick, Mathias S. and Kaever, Volkhard and Schmidt, Alexander and Dehio, Christoph. (2013) Dual input control : activation of the Bartonella henselae VirB/D4 type IV secretion system by the stringent sigma factor RpoH1 and the BatR/BatS two-component system. Molecular microbiology, Vol. 90, H. 4. pp. 756-775.

Eicher, Simone and Dehio, Christoph. (2013) Systems-level analysis of host-pathogen interaction using RNA interference. New biotechnology, Vol. 30, H. 3. pp. 308-313.

Goepfert, Arnaud and Harms, Alexander and Schirmer, Tilman and Dehio, Christoph. (2013) Type II Toxin-Antitoxin Loci: The fic Family. In: Prokaryotic Toxin-Antitoxins. Heidelberg, pp. 177-187.

2012

Engel, Philipp and Goepfert, Arnaud and Stanger, Frédéric V. and Harms, Alexander and Schmidt, Alexander and Schirmer, Tilman and Dehio, Christoph. (2012) Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482 (7383). pp. 107-110.

Harms, Alexander and Dehio, Christoph. (2012) Intruders below the Radar : Molecular Pathogenesis of Bartonella spp. Clinical microbiology reviews, Vol. 25, H. 1. pp. 42-78.

Pulliainen, Arto Tapio and Dehio, Christoph. (2012) Persistence of Bartonella spp. stealth pathogens : from sub-clinical infections to vasoproliferative tumour formation. FEMS Microbiology Reviews, 36 (3). pp. 563-599.

2011

Truttmann, Matthias C. and Guye, Patrick and Dehio, Christoph. (2011) BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures. PLoS ONE, 6 (10). e25106.

Truttmann, Matthias C. and Misselwitz, Benjamin and Huser, Sonja and Hardt, Wolf-Dietrich and Critchley, David R. and Dehio, Christoph. (2011) Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake. Journal of Cell Science, 124 (21). pp. 3591-3602.

Schröder, Gunnar and Schuelein, Ralf and Quebatte, Maxime and Dehio, Christoph. (2011) Conjugative DNA transfer into human cells by the VirB/VirD4 type IV secretion system of the bacterial pathogen Bartonella henselae. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 35. pp. 14643-14648.

Engel, Philipp and Salzburger, Walter and Liesch, Marius and Chang, Chao-Chin and Maruyama, Soichi and Lanz, Christa and Calteau, Alexandra and Lajus, Aurélie and Médigue, Claudine and Schuster, Stephan C. and Dehio, Christoph. (2011) Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella. PLoS Genetics, 7 (2). e1001296.

Fernández-González, Esther and de Paz, Héctor D. and Alperi, Anabel and Agúndez, Leticia and Faustmann, Marco and Sangari, Félix J. and Dehio, Christoph and Llosa, Matxalen. (2011) Transfer of R388 derivatives by a pathogenesis-associated type IV secretion system into both bacteria and human cells. Journal of bacteriology, Vol. 193, H. 22. pp. 6257-6265.

2010

de Paz, Héctor D. and Larrea, Delfina and Zunzunegui, Sandra and Dehio, Christoph and de la Cruz, Fernando and Llosa, Matxalen. (2010) Functional dissection of the conjugative coupling protein TrwB. Journal of bacteriology, 192 (11). pp. 2655-2669.

Quebatte, Maxime and Dehio, Michaela and Tropel, David and Basler, Andrea and Toller, Isabella and Raddatz, Guenter and Engel, Philipp and Huser, Sonja and Schein, Hermine and Lindroos, Hillevi L. and Andersson, Siv G. E. and Dehio, Christoph. (2010) The BatR/BatS two-component regulatory system controls the adaptive response of Bartonella henselae during human endothelial cell infection. Journal of bacteriology, 192 (13). pp. 3352-3367.

Vayssier-Taussat, Muriel and Le Rhun, Danielle and Deng, Hong Kuan and Biville, Francis and Cescau, Sandra and Danchin, Antoine and Marignac, Geneviève and Lenaour, Evelyne and Boulouis, Henri Jean and Mavris, Maria and Arnaud, Lionel and Yang, Huanming and Wang, Jing and Quebatte, Maxime and Engel, Philipp and Saenz, Henri and Dehio, Christoph. (2010) The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes. PLoS Pathogens, Vol. 6, H. 6 , e1000946.