Items where Author is "Eckert, Anne"

2013

Hennings, Johannes M. and Kohli, Martin A. and Czamara, Darina and Giese, Maria and Eckert, Anne and Wolf, Christiane and Heck, Angela and Domschke, Katharina and Arolt, Volker and Baune, Bernhard T. and Horstmann, Sonja and Brückl, Tanja and Klengel, Torsten and Menke, Andreas and Müller-Myhsok, Bertram and Ising, Marcus and Uhr, Manfred and Lucae, Susanne. (2013) Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach. PLoS One, 8 (6). e64947.

Giese, Maria and Unternaehrer, Eva and Brand, Serge and Calabrese, Pasquale and Holsboer-Trachsler, Edith and Eckert, Anne. (2013) The interplay of stress and sleep impacts BDNF level. PloS one, Vol. 8, H. 10 , e76050.

2011

Brown, Steven A. and Schmitt, Karen and Eckert, Anne. (2011) Aging and circadian disruption : causes and effects. Aging, Vol. 3, H. 8. pp. 813-817.

Pagani, Lucia and Eckert, Anne. (2011) Amyloid-Beta interaction with mitochondria. International journal of Alzheimer's disease, Vol. 2011 , 925050.

Yanagisawa, Katsuhiko and Fantini, Jacques and Chakrabartty, Avijit and Eckert, Anne. (2011) Aβ behavior on neuronal membranes : : aggregation and toxicities. International journal of Alzheimer's disease, Vol. 2011 , 286536.

Kulic, Luka and Wollmer, M. Axel and Rhein, Virginie and Pagani, Lucia and Kuehnle, Katrin and Cattepoel, Susann and Tracy, Jay and Eckert, Anne and Nitsch, Roger M.. (2011) Combined expression of tau and the Harlequin mouse mutation leads to increased mitochondrial dysfunction, tau pathology and neurodegeneration. Neurobiology of aging, Vol. 32, H. 10. pp. 1827-1838.

Lim, Yun-An and Grimm, Amandine and Giese, Maria and Mensah-Nyagan, Ayikoe Guy and Villafranca, J. Ernest and Ittner, Lars M. and Eckert, Anne and Götz, Jürgen. (2011) Inhibition of the mitochondrial enzyme ABAD restores the amyloid-?-mediated deregulation of estradiol. PLoS one, Vol. 6, H. 12 , e28887.

Strosznajder, Joanna B. and Cieslik, Magdalena and Cakala, Magdalena and Jesko, Henryk and Eckert, Anne and Strosznajder, Robert P.. (2011) Lipoxygenases and poly(ADP-ribose) polymerase in amyloid beta cytotoxicity. Neurochemical research, Vol. 36, H. 5. pp. 839-848.

Eckert, Anne and Schmitt, Karen and Götz, Jürgen. (2011) Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity. Alzheimer’s research & therapy, Vol. 3, H. 2. p. 15.

Götz, Jürgen and Eckert, Anne and Matamales, Miriam and Ittner, Lars M. and Liu, Xin. (2011) Modes of Aβ toxicity in Alzheimer's disease. Cellular and Molecular Life Sciences, Vol. 68, no. 20. pp. 3359-3375.

Pagani, Lucia and Schmitt, Karen and Meier, Fides and Izakovic, Jan and Roemer, Konstanze and Viola, Antoine and Cajochen, Christian and Wirz-Justice, Anna and Brown, Steven A. and Eckert, Anne. (2011) Serum factors in older individuals change cellular clock properties. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 17. pp. 7218-7223.

Brown, Steven A. and Pagani, Lucia and Cajochen, Christian and Eckert, Anne. (2011) Systemic and cellular reflections on ageing and the circadian oscillator : a mini-review. Gerontology, 57 (5). pp. 427-434.

2010

Lim, Yun-An and Rhein, Virginie and Baysang, Ginette and Meier, Fides and Poljak, Anne and Raftery, Mark J. and Guilhaus, Michael and Ittner, Lars M. and Eckert, Anne and Götz, Jürgen. (2010) Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics, Vol. 10, H. 8. pp. 1621-1633.

Eckert, Anne and Schulz, Kathrin L. and Rhein, Virginie and Götz, Jürgen. (2010) Convergence of amyloid-beta and tau pathologies on mitochondria in vivo. Molecular neurobiology, Vol. 41, H. 2/3. pp. 107-114.

Ittner, Lars M. and Ke, Yazi D. and Delerue, Fabien and Bi, Mian and Gladbach, Amadeus and van Eersel, Janet and Wölfing, Heidrun and Chieng, Billy C. and Christie, MacDonald J. and Napier, Ian A. and Eckert, Anne and Staufenbiel, Matthias and Hardeman, Edna and Götz, Jürgen. (2010) Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models. Cell, Vol. 142, H. 3. pp. 387-397.

Götz, Jürgen and Lim, Yun-An and Ke, Yazi D. and Eckert, Anne and Ittner, Lars M.. (2010) Dissecting toxicity of tau and beta-amyloid. Neuro-degenerative Diseases, 7 (1-3). pp. 10-12.

Rhein, Virginie and Giese, Maria and Baysang, Ginette and Meier, Fides and Rao, Stefania and Schulz, Kathrin L. and Hamburger, Matthias and Eckert, Anne. (2010) Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure. PLoS one, Vol. 5 , e12359.

Müller, Walter E. and Eckert, Anne and Kurz, Christopher and Eckert, Gunter Peter and Leuner, Kristina. (2010) Mitochondrial dysfunction : common final pathway in brain aging and Alzheimer's disease : therapeutic aspects. Molecular neurobiology, Vol. 41, H. 2/3. pp. 159-171.

Schaeffer, Véronique and Meyer, Laurence and Patte-Mensah, Christine and Eckert, Anne and Mensah-Nyagan, Ayikoe G.. (2010) Sciatic nerve injury induces apoptosis of dorsal root ganglion satellite glial cells and selectively modifies neurosteroidogenesis in sensory neurons. Glia, Vol. 58, No. 2. pp. 169-180.

Pagani, Lucia and Semenova, Ekaterina A. and Moriggi, Ermanno and Revell, Victoria L. and Hack, Lisa M. and Lockley, Steven W. and Arendt, Josephine and Skene, Debra J. and Meier, Fides and Izakovic, Jan and Wirz-Justice, Anna and Cajochen, Christian and Sergeeva, Oksana J. and Cheresiz, Sergei V. and Danilenko, Konstantin V. and Eckert, Anne and Brown, Steven A.. (2010) The physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts. PLoS one, Vol. 5, H. 10 , e13376.

2009

Rhein, Virginie and Song, Xiaomin and Wiesner, Andreas and Ittner, Lars M. and Baysang, Ginette and Meier, Fides and Ozmen, Laurence and Bluethmann, Horst and Dröse, Stefan and Brandt, Ulrich and Savaskan, Egemen and Czech, Christian and Götz, Jürgen and Eckert, Anne. (2009) Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 47. pp. 20057-20062.

Eckert, Anne. (2009) Spezielle Arzneimittelinteraktionen. Therapeutische Umschau, Bd. 66, H. 6. pp. 485-492.

2008

Schaeffer, Véronique and Meyer, Laurence and Patte-Mensah, Christine and Eckert, Anne and Mensah-Nyagan, Ayikoe G.. (2008) Dose-dependent and sequence-sensitive effects of amyloid-beta peptide on neurosteroidogenesis in human neuroblastoma cells. Neurochemistry international, vol. 52, no. 6. pp. 948-955.

Eckert, Anne and Hauptmann, Susanne and Scherping, Isabel and Meinhardt, Jessica and Rhein, Virginie and Dröse, Stefan and Brandt, Ulrich and Fändrich, Marcus and Müller, Walter E. and Götz, Jürgen. (2008) Oligomeric and fibrillar species of beta-amyloid (A beta 42) both impair mitochondrial function in P301L tau transgenic mice. Journal of molecular medicine, Vol. 86, no. 11. pp. 1255-1267.

Eckert, Anne and Hauptmann, Susanne and Scherping, Isabel and Rhein, Virginie and Müller-Spahn, Franz and Götz, Jürgen and Müller, Walter E.. (2008) Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic mice. Neuro-degenerative Diseases, 5 (3-4). pp. 157-159.

2007

Chalimoniuk, Ma?gorzata and Stolecka, Anna and Caka?a, Magdalena and Hauptmann, Susane and Schulz, Kris and Lipka, Uta and Leuner, Kristine and Eckert, Anne and Muller, Walter E. and Strosznajder, Joanna B.. (2007) Amyloid beta enhances cytosolic phospholipase A2 level and arachidonic acid release via nitric oxide in APP-transfected PC12 cells. Acta biochimica Polonica, Vol. 54, Nr. 3. pp. 611-623.

Rhein, Virginie and Eckert, Anne. (2007) Effects of Alzheimer's amyloid-beta and tau protein on mitochondrial function : role of glucose metabolism and insulin signalling. Archives of physiology and biochemistry, Vol. 113, No. 3. pp. 131-141.

Schindowski, Katharina and Eckert, Anne and Peters, Jürgen and Gorriz, Corinna and Schramm, Uta and Weinandi, Thomas and Maurer, Konrad and Frölich, Lutz and Müller, Walter E.. (2007) Increased T-cell reactivity and elevated levels of CD8+ memory T-cells in Alzheimer's disease-patients and T-cell hyporeactivity in an Alzheimer's disease-mouse model : implications for immunotherapy. Neuromolecular medicine, Vol. 9, No. 4. pp. 340-354.

Leschik, Julia and Welzel, Alfred and Weissmann, Carina and Eckert, Anne and Brandt, Roland. (2007) Inverse and distinct modulation of tau-dependent neurodegeneration by presenilin 1 and amyloid-beta in cultured cortical neurons : evidence that tau phosphorylation is the limiting factor in amyloid-beta-induced cell death. Journal of neurochemistry, Vol. 101, H. 5. pp. 1303-1315.

Leuner, Kristina and Hauptmann, Susanne and Abdel-Kader, Reham and Scherping, Isabel and Keil, Uta and Strosznajder, Johanna B. and Eckert, Anne and Müller, Walter E.. (2007) Mitochondrial dysfunction: the first domino in brain aging and Alzheimer's disease? Antioxidants & redox signaling, Vol. 9, No. 10. pp. 1659-1675.

Abdel-Kader, Reham and Hauptmann, Susanne and Keil, Uta and Scherping, Isabel and Leuner, Kristina and Eckert, Anne and Müller, Walter E.. (2007) Stabilization of mitochondrial function by Ginkgo biloba extract (EGb 761). Pharmacological research, Vol. 56, No. 6. pp. 493-502.

Savaskan, Egemen and Jockers, Ralf and Ayoub, Mohammed and Angeloni, Debora and Fraschini, Franco and Flammer, Josef and Eckert, Anne and Müller-Spahn, Franz and Meyer, Peter. (2007) The MT2 melatonin receptor subtype is present in human retina and decreases in Alzheimer's disease. Current Alzheimer research, Vol. 4, No. 1. pp. 47-51.

Copanaki, Ekaterini and Schürmann, Tina and Eckert, Anne and Leuner, Kristina and Müller, Walter E. and Prehn, Jochen H. M. and Kögel, Donat. (2007) The amyloid precursor protein potentiates CHOP induction and cell death in response to ER Ca2+ depletion. Biochimica et biophysica acta. Molecular cell research, Vol. 1773, Issue 2. pp. 157-165.

2006

Schuessel, Katrin and Frey, Claudia and Jourdan, Claudia and Keil, Uta and Weber, Claudia C. and Müller-Spahn, Franz and Müller, Walter E. and Eckert, Anne. (2006) Aging sensitizes toward ROS formation and lipid peroxidation in PS1M146L transgenic mice. Free radical biology & medicine, Vol. 40, H. 5. pp. 850-562.

Hauptmann, Susanne and Keil, Uta and Scherping, Isabel and Bonert, Astrid and Eckert, Anne and Müller, Walter E.. (2006) Mitochondrial dysfunction in sporadic and genetic Alzheimer's disease. Experimental gerontology, Vol. 41, no. 7. pp. 668-673.

Keil, Uta and Hauptmann, Susanne and Bonert, Astrid and Scherping, Isabel and Eckert, Anne and Müller, Walter E.. (2006) Mitochondrial dysfunction induced by disease relevant AbetaPP and tau protein mutations. Journal of Alzheimer's disease, Vol. 9, no. 2. pp. 139-146.

Schaeffer, Véronique and Patte-Mensah, Christine and Eckert, Anne and Mensah-Nyagan, Ayikoe G.. (2006) Modulation of neurosteroid production in human neuroblastoma cells by Alzheimer's disease key proteins. Journal of neurobiology, Vol. 66, H. 8. pp. 868-881.

Keil, Uta and Scherping, Isabel and Hauptmann, Susanne and Schuessel, Katin and Eckert, Anne and Müller, Walter E.. (2006) Piracetam improves mitochondrial dysfunction following oxidative stress. British journal of pharmacology, Vol. 147, no. 2. pp. 199-208.

2005

Schuessel, Katrin and Schäfer, Stephanie and Bayer, Thomas A. and Czech, Christian and Pradier, Laurent and Müller-Spahn, Franz and Müller, Walter E. and Eckert, Anne. (2005) Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice. Neurobiology of disease, Vol. 18, no. 1. pp. 89-99.

David, Della C. and Hauptmann, Susanne and Scherping, Isabel and Schuessel, Katrin and Keil, Uta and Rizzu, Patrizia and Ravid, Rivka and Dröse, Stefan and Brandt, Ulrich and Müller, Walter E. and Eckert, Anne and Götz, Jürgen. (2005) Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. Journal of biological chemistry, Vol. 280, H. 25. pp. 23802-23814.

Savaskan, Egemen and Ayoub, Mohammed A. and Ravid, Rivka and Angeloni, Debora and Fraschini, Franco and Meier, Fides and Eckert, Anne and Müller-Spahn, Franz and Jockers, Ralf. (2005) Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease. Journal of pineal research, Vol. 38, no. 1. pp. 10-16.

Eckert, Anne and Keil, Uta and Scherping, Isabel and Hauptmann, Susanne and Müller, Walter E.. (2005) Stabilization of mitochondrial membrane potential and improvement of neuronal energy metabolism by Ginkgo biloba extract EGb 761. Annals of the New York Academy of Sciences, Vol. 1056. pp. 474-485.

Eckert, Anne. (2005) Stellenwert von Nimodipin in der Demenztherapie : Calcium-Hypothese der Demenz. Pharmazie in unserer Zeit, Vol. 34, issue 5. pp. 392-398.

2004

Strosznajder, Joanna B. and Je?ko, Henryk and Zambrzycka, Agata and Eckert, Anne and Chalimoniuk, Ma?gorzata. (2004) Age-related alteration of activity and gene expression of endothelial nitric oxide synthase in different parts of the brain in rats. Neuroscience letters, Vol. 370, H. 2-3. pp. 175-179.

Keil, Uta and Bonert, Astrid and Marques, Celio A. and Scherping, Isabel and Weyermann, Jörg and Strosznajder, Joanna B. and Müller-Spahn, Franz and Haass, Christian and Czech, Christian and Pradier, Laurent and Müller, Walter E. and Eckert, Anne. (2004) Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis. Journal of biological chemistry, Vol. 279, H. 48. pp. 50310-50320.

2003

Bayer, Thomas A. and Schäfer, Stephanie and Simons, Andreas and Kemmling, André and Kamer, Thomas and Tepest, Ralf and Eckert, Anne and Schüssel, Katrin and Eikenberg, Oliver and Sturchler-Pierrat, Christine and Abramowski, Dorothee and Staufenbiel, Matthias and Multhaup, Gerd. (2003) Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice. Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 24. pp. 14187-14192.

Schindowski, Katharina and Kratzsch, Tilmann and Peters, Jürgen and Steiner, Barbara and Leutner, Silke and Touchet, Natalie and Maurer, Konrad and Czech, Christian and Pradier, Laurent and Frölich, Lutz and Müller, Walter E. and Eckert, Anne. (2003) Impact of aging : sporadic, and genetic risk factors on vulnerability to apoptosis in Alzheimer's disease. Neuromolecular medicine, Vol. 4, No. 3. pp. 161-178.

Eckert, Anne and Marques, Celio A. and Keil, Uta and Schüssel, Katrin and Müller, Walter E.. (2003) Increased apoptotic cell death in sporadic and genetic Alzheimer's disease. Annals of the New York Academy of Sciences, vol. 1010. pp. 604-609.

Eckert, Anne and Keil, Uta and Marques, Celio A. and Bonert, Astrid and Frey, Claudia and Schüssel, Katrin and Müller, Walter E.. (2003) Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease. Biochemical Pharmacology, Volume 76, Issue 10. pp. 1184-1193.

Marques, Celio A. and Keil, Uta and Bonert, Astrid and Steiner, Barbara and Haass, Christian and Muller, Walter E. and Eckert, Anne. (2003) Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation : oxidative stress, caspases, and the JNK pathway. Journal of biological chemistry, Vol. 278, H. 30. pp. 28294-28302.

Kögel, Donat and Schomburg, Robert and Schürmann, Tina and Reimertz, Claus and König, Hans-Georg and Poppe, Monika and Eckert, Anne and Müller, Walter E. and Prehn, Jochen H. M.. (2003) The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis. Journal of neurochemistry, Vol. 87, H. 1. pp. 248-256.

2002

Schindowski, Katharina and Fröhlich, Lutz and Maurer, Konrad and Müller, Walter E. and Eckert, Anne. (2002) Age-related impairment of human T lymphocytes' activation : specific differences between CD4(+) and CD8(+) subsets. Mechanisms of ageing and development, Vol. 123, no. 4. pp. 375-390.

Eckert, Anne. (2002) Alois Alzheimer und die Alzheimer Krankheit : aus der Frankfurter Anstalt für Irre und Epileptische. Pharmazie in unserer Zeit, Vol. 31, issue 4. pp. 356-360.

Leutz, Steffen and Steiner, Barbara and Marques, Celio A. and Haass, Christian and Müller, Walter E. and Eckert, Anne. (2002) Reduction of trophic support enhances apoptosis in PC12 cells expressing Alzheimer's APP mutation and sensitizes cells to staurosporine-induced cell death. Journal of molecular neuroscience, Vol. 18, No. 3. pp. 189-201.