Items where Author is "Hirsch, E."

2013

Zotes, T. M. and Arias, C. F. and Fuster, J. J. and Spada, R. and Perez-Yague, S. and Hirsch, E. and Wymann, M. and Carrera, A. C. and Andres, V. and Barber, D. F.. (2013) PI3K p110γ deletion attenuates murine atherosclerosis by reducing macrophage proliferation but not polarization or apoptosis in lesions. PLoS one, Vol. 8, H. 8 , e72674.

Walser, R. and Burke, J. E. and Gogvadze, E. and Bohnacker, T. and Zhang, X. and Hess, D. and Kuenzi, P. and Leitges, M. and Hirsch, E. and Williams, R. L. and Laffargue, M. and Wymann, M. P.. (2013) PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control. PLoS Biology, Vol. 11, H. 6 , e1001587.

Schmidt, C. and Schneble, N. and Muller, J. P. and Bauer, R. and Perino, A. and Marone, R. and Rybalkin, S. D. and Wymann, M. P. and Hirsch, E. and Wetzker, R.. (2013) Phosphoinositide 3-kinase gamma mediates microglial phagocytosis via lipid kinase-independent control of cAMP. Neuroscience, Vol. 233. pp. 44-53.

Collmann, E. and Bohnacker, T. and Marone, R. and Dawson, J. and Rehberg, M. and Stringer, R. and Krombach, F. and Burkhart, C. and Hirsch, E. and Hollingworth, G. J. and Thomas, M. and Wymann, M. P.. (2013) Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergy. Journal of allergy and clinical immunology, Vol. 132, H. 4. pp. 959-968.

2012

Fougerat, A. and Smirnova, N. F. and Gayral, S. and Malet, N. and Hirsch, E. and Wymann, M. P. and Perret, B. and Martinez, L. O. and Douillon, M. and Laffargue, M.. (2012) Key role of PI3Kgamma in monocyte chemotactic protein-1-mediated amplification of PDGF-induced aortic smooth muscle cell migration. British journal of pharmacology, Vol. 166, no. 5. pp. 1643-1653.

2011

Perino, A. and Ghigo, A. and Ferrero, E. and Morello, F. and Santulli, G. and Baillie, G. S. and Damilano, F. and Dunlop, A. J. and Pawson, C. and Walser, R. and Levi, R. and Altruda, F. and Silengo, L. and Langeberg, L. K. and Neubauer, G. and Heymans, S. and Lembo, G. and Wymann, M. P. and Wetzker, R. and Houslay, M. D. and Iaccarino, G. and Scott, J. D. and Hirsch, E.. (2011) Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ. Molecular cell, Vol. 42, H. 1. pp. 84-95.

2008

Fougerat, A. and Gayral, S. and Gourdy, P. and Schambourg, A. and Rückle, T. and Schwarz, M. K. and Rommel, C. and Hirsch, E. and Arnal, J. F. and Salles, J. P. and Perret, B. and Breton-Douillon, M. and Wymann, M. P. and Laffargue, M.. (2008) Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes. Circulation, Vol. 117, H. 10. pp. 1310-1317.

Ciraolo, E. and Iezzi, M. and Marone, R. and Marengo, S. and Curcio, C. and Costa, C. and Azzolino, O. and Gonella, C. and Rubinetto, C. and Wu, H. and Dastrù, W. and Martin, E. L. and Silengo, L. and Altruda, F. and Turco, E. and Lanzetti, L. and Musiani, P. and Rückle, T. and Rommel, C. and Backer, J. M. and Forni, G. and Wymann, M. P. and Hirsch, E.. (2008) Phosphoinositide 3-kinase p110beta activity : key role in metabolism and mammary gland cancer but not development. Science signaling, Vol. 1, H. 36 , ra3.