Items where Author is "Jakob, Roman P."

2018

Sager, Christoph P. and Fiege, Brigitte and Zihlmann, Pascal and Vannam, Raghu and Rabbani, Said and Jakob, Roman P. and Preston, Roland C. and Zalewski, Adam and Maier, Timm and Peczuh, Mark W. and Ernst, Beat. (2018) The price of flexibility - a case study on septanoses as pyranose mimetics. Chemical Science, 9. pp. 646-654.

2017

Navarra, Giulio and Zihlmann, Pascal and Jakob, Roman P. and Stangier, Katia and Preston, Roland C. and Rabbani, Said and Smiesko, Martin and Wagner, Bea and Maier, Timm and Ernst, Beat. (2017) Carbohydrate-Lectin Interactions - An Unexpected Contribution to Affinity. ChemBioChem, 18 (6). pp. 539-544.

24 March 2016

Herbst, Dominik A. and Jakob, Roman P. and Zähringer, Franziska and Maier, Timm. (2016) Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases. Nature, 531 (7595). pp. 533-537.

February 2016

Preston, Roland C. and Jakob, Roman P. and Binder, Florian P. C. and Sager, Christoph P. and Ernst, Beat and Maier, Timm. (2016) E-selectin ligand complexes adopt an extended high-affinity conformation. Journal of Molecular Cell Biology, 8 (1). pp. 62-72.

2016

Sauer, Maximilian M. and Jakob, Roman P. and Eras, Jonathan and Baday, Sefer and Eris, Deniz and Navarra, Giulio and Bernèche, Simon and Ernst, Beat and Maier, Timm and Glockshuber, Rudi. (2016) Catch-bond mechanism of the bacterial adhesin FimH. Nature communications, 7. p. 10738.

Jakob, Roman P. and Schmidpeter, Philipp A. M. and Koch, Johanna R. and Schmid, Franz X. and Maier, Timm. (2016) Structural and Functional Characterization of a Novel Family of Cyclophilins, the AquaCyps. PLoS One, 11 (6). e0157070.

2015

Jakob, Roman P. and Koch, Johanna R. and Burmann, Björn M. and Schmidpeter, Philipp A. M. and Hunkeler, Moritz and Hiller, Sebastian and Schmid, Franz X. and Maier, Timm. (2015) Dimeric structure of the bacterial extracellular foldase PrsA. Journal of Biological Chemistry, 290 (6). pp. 3278-3292.

Kleeb, Simon and Pang, Lijuan and Mayer, Katharina and Eris, Deniz and Sigl, Anja and Preston, Roland C. and Zihlmann, Pascal and Sharpe, Timothy and Jakob, Roman P. and Abgottspon, Daniela and Hutter, Aline S. and Scharenberg, Meike and Jiang, Xiaohua and Navarra, Giulio and Rabbani, Said and Smiesko, Martin and Lüdin, Nathalie and Bezençon, Jacqueline and Schwardt, Oliver and Maier, Timm and Ernst, Beat. (2015) FimH Antagonists: Bioisosteres To Improve the in Vitro and in Vivo PK/PD Profile. Journal of Medicinal Chemistry, 58 (5). pp. 2221-2239.

Fiege, Brigitte and Rabbani, Said and Preston, Roland C. and Jakob, Roman P. and Zihlmann, Pascal and Schwardt, Oliver and Jiang, Xiaohua and Maier, Timm and Ernst, Beat. (2015) The Tyrosine Gate of the Bacterial Lectin FimH : a Conformational Analysis by NMR Spectroscopy and X-ray Crystallography. ChemBioChem, 16 (8). pp. 1235-1246.

2014

Bukhari, Habib S. T. and Jakob, Roman P. and Maier, Timm. (2014) Evolutionary origins of the multienzyme architecture of giant fungal Fatty Acid synthase. Structure, Vol. 22, H. 12. pp. 1775-1785.

2013

Gruss, Fabian and Zähringer, Franziska and Jakob, Roman P. and Burmann, Björn M. and Hiller, Sebastian and Maier, Timm. (2013) The structural basis of autotransporter translocation by TamA. Nature structural & molecular biology, Vol. 20, no. 11. pp. 1318-1320.