Items where Author is "Rüegg, Markus A."

Article

McKee, Karen K. and Crosson, Stephanie C. and Meinen, Sarina and Reinhard, Judith R. and Rüegg, Markus A. and Yurchenco, Peter D.. (2017) Chimeric protein repair of laminin polymerization ameliorates muscular dystrophy phenotype. Journal of Clinical Investigation, 127 (3). pp. 1075-1089.

Willmann, Raffaella and Gordish-Dressman, Heather and Meinen, Sarina and Rüegg, Markus A. and Yu, Qing and Nagaraju, Kanneboyina and Kumar, Ayar and Girgenrath, Mahasweta and Coffey, Caroline B. M. and Cruz, Vivian and Van Ry, Pam M. and Bogdanik, Laurent and Lutz, Cathleen and Rutkowski, Anne and Burkin, Dean J.. (2017) Improving Reproducibility of Phenotypic Assessments in the DyW Mouse Model of Laminin-α2 Related Congenital Muscular Dystrophy. Journal of Neuromuscular Diseases, 4 (2). pp. 115-126.

Reinhard, Judith R. and Lin, Shuo and McKee, Karen K. and Meinen, Sarina and Crosson, Stephanie C. and Sury, Maurizio and Hobbs, Samantha and Maier, Geraldine and Yurchenco, Peter D. and Rüegg, Markus A.. (2017) Linker proteins restore basement membrane and correct LAMA2-related muscular dystrophy in mice. Science Translational Medicine, 9 (396). eaal4649.

Rion, Nathalie and Rüegg, Markus A.. (2017) LncRNA-encoded peptides: More than translational noise? Cell Research, 27 (5). pp. 604-605.

Bozadjieva, Nadejda and Blandino-Rosano, Manuel and Chase, Jennifer and Dai, Xiao-Qing and Cummings, Kelsey and Gimeno, Jennifer and Dean, Danielle and Powers, Alvin C. and Gittes, George K. and Rüegg, Markus A. and Hall, Michael N. and MacDonald, Patrick E. and Bernal-Mizrachi, Ernesto. (2017) Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion. Journal of Clinical Investigation. pp. 1-15.

Blandino-Rosano, Manuel and Barbaresso, Rebecca and Jimenez-Palomares, Margarita and Bozadjieva, Nadejda and Werneck-de-Castro, Joao Pedro and Hatanaka, Masayuki and Mirmira, Raghavendra G. and Sonenberg, Nahum and Liu, Ming and Rüegg, Markus A. and Hall, Michael N. and Bernal-Mizrachi, Ernesto. (2017) Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing. Nature Communications, 8. p. 16014.

Brockhoff, Marielle and Rion, Nathalie and Chojnowska, Kathrin and Wiktorowicz, Tatiana and Eickhorst, Christopher and Erne, Beat and Frank, Stephan and Angelini, Corrado and Furling, Denis and Rüegg, Markus A. and Sinnreich, Michael and Castets, Perrine. (2017) Targeting deregulated AMPK/mTORC1 pathways improves muscle function in myotonic dystrophy type I. Journal of Clinical Investigation, 127 (2). pp. 549-563.

Reinhard, Judith R. and Kriz, Alexander and Galic, Milos and Angliker, Nico and Rajalu, Mathieu and Vogt, Kaspar E. and Rüegg, Markus A.. (2016) The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nature Communications, 7. p. 11613.

Guridi, Maitea and Kupr, Barbara and Romanino, Klaas and Lin, Shuo and Falcetta, Denis and Tintignac, Lionel and Rüegg, Markus A.. (2016) Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism. Skeletal Muscle, 6 (13). pp. 1-14.

Zhang, Lianjun and Tschumi, Benjamin O. and Lopez-Mejia, Isabel C. and Oberle, Susanne G. and Meyer, Marten and Samson, Guerric and Rüegg, Markus A. and Hall, Michael N. and Fajas, Lluis and Zehn, Dietmar and Mach, Jean-Pierre and Donda, Alena and Romero, Pedro. (2016) Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner. Cell Reports , 14 (5). pp. 1206-1217.

Schell, Christoph and Kretz, Oliver and Liang, Wei and Kiefer, Betina and Schneider, Simon and Sellung, Dominik and Bork, Tillmann and Leiber, Christian and Rüegg, Markus A. and Mallidis, Con and Schlatt, Stefan and Mayerhofer, Artur and Huber, Tobias B. and Grahammer, Florian. (2016) The Rapamycin-Sensitive Complex of Mammalian Target of Rapamycin Is Essential to Maintain Male Fertility. American Journal of Pathology, 186 (2). pp. 324-336.

Ruegsegger, Céline and Stucki, David M. and Steiner, Silvio and Angliker, Nico and Radecke, Julika and Keller, Eva and Zuber, Benoît and Rüegg, Markus A. and Saxena, Smita. (2016) Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology. Neuron, 89 (1). pp. 129-146.

Castets, Perrine and Frank, Stephan and Sinnreich, Michael and Rüegg, Markus A.. (2016) "Get the Balance Right": Pathological Significance of Autophagy Perturbation in Neuromuscular Disorders. Journal of Neuromuscular Diseases, 3 (2). pp. 127-155.

Shende, Pankaj and Xu, Lifen and Morandi, Christian and Pentassuglia, Laura and Heim, Philippe and Lebboukh, Sonia and Berthonneche, Corinne and Pedrazzini, Thierry and Kaufmann, Beat A. and Hall, Michael N. and Rüegg, Markus A. and Brink, Marijke. (2016) Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy. Cardiovascular Research, 109 (1). pp. 103-114.

Ding, Xiaolei and Bloch, Wilhelm and Iden, Sandra and Rüegg, Markus A. and Hall, Michael N. and Leptin, Maria and Partridge, Linda and Eming, Sabine A.. (2016) mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nature Communications, 7. p. 13226.

Kleinert, Maximilian and Parker, Benjamin L. and Chaudhuri, Rima and Fazakerley, Daniel J. and Serup, Annette and Thomas, Kristen C. and Krycer, James R. and Sylow, Lykke and Fritzen, Andreas M. and Hoffman, Nolan J. and Jeppesen, Jacob and Schjerling, Peter and Rüegg, Markus A. and Kiens, Bente and James, David E. and Richter, Erik A.. (2016) mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3. Molecular Metabolism, 5 (8). pp. 646-655.

Aimi, Fabio and Georgiopoulou, Stavroula and Kalus, Ina and Lehner, Fabienne and Hegglin, Alica and Limani, Përparim and Gomes de Lima, Vinicius and Rüegg, Markus A. and Hall, Michael N. and Lindenblatt, Nicole and Haas, Elvira and Battegay, Edouard J. and Humar, Rok. (2015) Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult. Scientific Reports, 5. p. 17705.

Guridi, Maitea and Tintignac, Lionel A. and Lin, Shuo and Kupr, Barbara and Castets, Perrine and Rüegg, Markus A.. (2015) Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21. Science Signaling, 8 (402). ra113.

Angliker, Nico and Burri, Michael and Zaichuk, Mariana and Fritschy, Jean-Marc and Rüegg, Markus A.. (2015) mTORC1 and mTORC2 have largely distinct functions in Purkinje cells. European Journal of Neuroscience, 42 (8). pp. 2595-2612.

Zhang, Yina and Lin, Shuo and Karakatsani, Andromachi and Rüegg, Markus A. and Kröger, Stephan. (2015) Differential regulation of AChR clustering in the polar and equatorial region of murine muscle spindles. European Journal of Neuroscience, 41 (1). pp. 69-78.

Tintignac, Lionel A. and Brenner, Hans-Rudolf and Rüegg, Markus A.. (2015) Mechanisms Regulating Neuromuscular Junction Development and Function and Causes of Muscle Wasting. Physiological Reviews, 95 (3). pp. 809-852.

Lopez, Rubén J. and Mosca, Barbara and Treves, Susan and Maj, Marcin and Bergamelli, Leda and Calderon, Juan C. and Bentzinger, C. Florian and Romanino, Klaas and Hall, Michael N. and Rüegg, Markus A. and Delbono, Osvaldo and Caputo, Carlo and Zorzato, Francesco. (2015) Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex. Biochemical Journal, 466 (1). pp. 123-135.

Zhang, Lianjun and Tschumi, Benjamin O. and Corgnac, Stéphanie and Rüegg, Markus A. and Hall, Michael N. and Mach, Jean-Pierre and Romero, Pedro and Donda, Alena. (2014) Mammalian target of rapamycin complex 1 orchestrates invariant NKT cell differentiation and effector function. Journal of Immunology, 193 (4). pp. 1759-1765.

Chou, Po-Chien and Oh, Won Jun and Wu, Chang-Chih and Moloughney, Joseph and Rüegg, Markus A. and Hall, Michael N. and Jacinto, Estela and Werlen, Guy. (2014) Mammalian target of rapamycin complex 2 modulates αβTCR processing and surface expression during thymocyte development. Journal of Immunology, 193 (3). pp. 1162-1170.

Miloslavski, Rachel and Cohen, Elad and Avraham, Adam and Iluz, Yifat and Hayouka, Zvi and Kasir, Judith and Mudhasani, Rajini and Jones, Stephen N. and Cybulski, Nadine and Rüegg, Markus A. and Larsson, Ola and Gandin, Valentina and Rajakumar, Arjuna and Topisirovic, Ivan and Meyuhas, Oded. (2014) Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner. Journal of Molecular Cell Biology, 6 (3). pp. 255-266.

Steiner, Esther and Enzmann, Gaby U. and Lyck, Ruth and Lin, Shuo and Rüegg, Markus A. and Kröger, Stephan and Engelhardt, Britta. (2014) The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions. Cell and Tissue Research, 358 (2). pp. 465-479.

Thomanetz, Venus and Angliker, Nico and Cloëtta, Dimitri and Lustenberger, Regula M. and Schweighauser, Manuel and Oliveri, Filippo and Suzuki, Noboru and Rüegg, Markus A.. (2013) Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology. The journal of cell biology, Vol. 201, H. 2. pp. 293-308.

Bentzinger, C. Florian and Lin, Shuo and Romanino, Klaas and Castets, Perrine and Guridi, Maitea and Summermatter, Serge and Handschin, Christoph and Tintignac, Lionel A. and Hall, Michael N. and Rüegg, Markus A.. (2013) Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy. Skeletal muscle, Vol. 3, H. 1 , 6.

Angliker, Nico and Rüegg, Markus A.. (2013) In vivo evidence for mTORC2-mediated actin cytoskeleton rearrangement in neurons. Bioarchitecture, 3 (4). pp. 113-118.

Cloëtta, Dimitri and Thomanetz, Venus and Baranek, Constanze and Lustenberger, Regula M. and Lin, Shuo and Oliveri, Filippo and Atanasoski, Suzana and Rüegg, Markus A.. (2013) Inactivation of mTORC1 in the Developing Brain Causes Microcephaly and Affects Gliogenesis. Journal of neuroscience, Vol. 33, H. 18. pp. 7799-7810.

Castets, Perrine and Rüegg, Markus A.. (2013) MTORC1 determines autophagy through ULK1 regulation in skeletal muscle. Autophagy, 9 (9). pp. 1435-1437.

Blättler, Sharon M. and Verdeguer, Francisco and Liesa, Marc and Cunningham, John T. and Vogel, Rutger O. and Chim, Helen and Liu, Huifei and Romanino, Klaas and Shirihai, Orian S. and Vazquez, Francisca and Rüegg, Markus A. and Shi, Yang and Puigserver, Pere. (2012) Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle. Molecular and cellular biology, 32 (16). pp. 3333-3346.

Meinen, Sarina and Lin, Shuo and Rüegg, Markus A. and Punga, Anna Rostedt. (2012) Fatigue and Muscle Atrophy in a Mouse Model of Myasthenia Gravis Is Paralleled by Loss of Sarcolemmal nNOS. PLoS one, Vol. 7, H. 8 , e44148.

Hagiwara, Asami and Cornu, Marion and Cybulski, Nadine and Polak, Pazit and Betz, Charles and Trapani, Francesca and Terracciano, Luigi and Heim, Markus H. and Rüegg, Markus A. and Hall, Michael N.. (2012) Hepatic mTORC2 activates glycolysis and lipogenesis through akt, glucokinase, and SREBP1c. Cell Metabolism, 15 (5). pp. 725-738.

Steiner, Esther and Enzmann, Gaby U. and Lin, Shuo and Ghavampour, Sharang and Hannocks, Melanie-Jane and Zuber, Benoît and Rüegg, Markus A. and Sorokin, Lydia and Engelhardt, Britta. (2012) Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation. Glia, 60 (11). pp. 1646-1659.

Blättler, Sharon M. and Cunningham, John T. and Verdeguer, Francisco and Chim, Helen and Haas, Wilhelm and Liu, Huifei and Romanino, Klaas and Rüegg, Markus A. and Gygi, Steven P. and Shi, Yang and Puigserver, Pere. (2012) Yin yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling. Cell Metabolism, 15 (4). pp. 505-517.

Meinen, Sarina and Lin, Shuo and Thurnherr, Raphael and Erb, Michael and Meier, Thomas and Rüegg, Markus A.. (2011) Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice. EMBO Molecular Medicine, 3 (8). pp. 465-479.

Romanino, Klaas and Mazelin, Laetitia and Albert, Verena and Conjard-Duplany, Agnès and Lin, Shuo and Bentzinger, C. Florian and Handschin, Christoph and Puigserver, Pere and Zorzato, Francesco and Schaeffer, Laurent and Gangloff, Yann-Gaël and Rüegg, Markus A.. (2011) Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 51. pp. 20808-20813.

Rüegg, Markus A. and Glass, David J.. (2010) Molecular mechanisms and treatment options for muscle wasting eiseases. Annual Review of Pharmacology and Toxicology, 51. pp. 373-395.

Willmann, Raffaella and Possekel, Stefanie and Dubach-Powell, Judith and Meier, Thomas and Rüegg, Markus A.. (2009) Mammalian animal models for Duchenne muscular dystrophy. Neuromuscular Disorders, 19 (4). pp. 241-249.

Risson, Valérie and Mazelin, Laetitia and Roceri, Mila and Sanchez, Hervé and Moncollin, Vincent and Corneloup, Claudine and Richard-Bulteau, Hélène and Vignaud, Alban and Baas, Dominique and Defour, Aurélia and Freyssenet, Damien and Tanti, Jean-François and Le-Marchand-Brustel, Yannick and Ferrier, Bernard and Conjard-Duplany, Agnès and Romanino, Klaas and Bauché, Stéphanie and Hantaï, Daniel and Mueller, Matthias and Kozma, Sara C. and Thomas, George and Rüegg, Markus A. and Ferry, Arnaud and Pende, Mario and Bigard, Xavier and Koulmann, Nathalie and Schaeffer, Laurent and Gangloff, Yann-Gaël. (2009) Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy. The Journal of cell biology, Vol. 187, H. 6. pp. 859-874.