Items where Division is "05 Faculty of Science > Departement Chemie > Former Organization Units Chemistry > Organische Chemie (Gademann)"

2017

Burn, Reto and Misson, Laëtitia and Meury, Marcel and Seebeck, Florian P.. (2017) Anaerobic Origin of Ergothioneine. Angewandte Chemie International Edition, 56 (41). pp. 12508-12511.

Thommen, Christophe and Neuburger, Markus and Gademann, Karl. (2017) Collective Syntheses of Icetexane Natural Products Based on Biogenetic Hypotheses. Chemistry - A European Journal, 23 (1). pp. 120-127.

2016

Crane, Erika A. and Gademann, Karl. (2016) Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis. Angewandte Chemie International Edition, 55 (12). pp. 3882-3902.

De Sarkar, Suman and Blom, Judith F. and Bethuel, Yann and Jüttner, Friedrich and Gademann, Karl. (2016) Allelopathic Activity of the Iron Chelator Anachelin – A Molecular Hybrid with a Dual Mode of Action. Helvetica Chimica Acta , 99 (10). pp. 760-773.

Faltermann, Susanne and Grundler, Verena and Gademann, Karl and Pernthaler, Jakob and Fent, Karl. (2016) Comparative effects of nodularin and microcystin-LR in zebrafish: 2. Uptake and molecular effects in eleuthero-embryos and adult liver with focus on endoplasmic reticulum stress. AquaticToxicology, 171. pp. 77-87.

Gomes, José and Daeppen, Christophe and Liffert, Raphael and Roesslein, Joel and Kaufmann, Elias and Heikinheim, Annakasia and Neuburger, Markus and Gademann, Karl. (2016) Formal Total Synthesis of (−)-Jiadifenolide and Synthetic Studies toward seco-Prezizaane-Type Sesquiterpenes. Journal of Organic Chemistry, 81 (22). pp. 11017-11034.

Kaufmann, Elias. The total synthesis of the glycosylated antibiotic fidaxomicin and methionine-derived iminium lactones. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Kerschgens, Isabel Patrizia. Surface engineering of algae and synthesis of pyrrolizidines for carbon dioxide capture applications. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Lascano, Santiago and Zhang, Kang-Da and Wehlauch, Robin and Gademann, Karl and Sakai, Naomi and Matile, Stefan. (2016) The third orthogonal dynamic covalent bond. Chemical Science, 7. pp. 4720-4724.

Pinto-Carbò, Marta and Sieber, Simon and Dessein, Steven and Wicker, Thomas and Verstraete, Brecht and Gademann, Karl and Eberl, Leo and Carlier, Aurelien. (2016) Evidence of horizontal gene transfer between obligate leaf nodule symbionts. ISME Journal, 10. pp. 2092-2105.

Scherer, Manuel. Synthesis and biological activity of cyanobacterial aeruginosins. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Scherer, Manuel and Bezold, Dominik and Gademann, Karl. (2016) Investigating the Toxicity of the Aeruginosin Chlorosulfopeptides by Chemical Synthesis. Angewandte Chemie International Edition, 55 (32). pp. 9427-9431.

Wehlauch, Robin. Design of bio-inspired materials and total synthesis of "Securinega" alkaloids. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

2015

Bader, Samuel L. and Luescher, Michael U. and Gademann, Karl. (2015) Synthesis of maculalactone A and derivatives for environmental fate tracking studies. Organic & biomolecular chemistry, Vol. 13, H. 1. pp. 199-206.

Bader, Samuel Leonhard. Higher marine phenylpropanoids : synthesis and biology of maculalactones and ophiodilactones. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Schmid, Fabian Felix. Total synthesis of (-)-pyridovericin and synthetic studies towards aetheramide B. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Sieber, Simon. Addressing fundamental questions in chemical biology through biochemical investigations of natural products. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Thommen, Christophe. Syntheses of taiwaniaquinoid and icetexane natural products based on biogenetic hypotheses. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

2014

Burch, Patrick and Chicca, Andrea and Gertsch, Jürg and Gademann, Karl. (2014) Functionally Optimized Neuritogenic Farinosone C Analogs : SAR-Study and Investigations on Their Mode of Action. ACS medicinal chemistry letters, Vol. 5, H. 2. pp. 172-177.

Burch, Patrick and Schmid, Fabian and Gademann, Karl. (2014) Neuritogenic surfaces using natural product analogs. Advanced healthcare materials, Vol. 3, H. 9. pp. 1415-1419.

Gomes, José Rui. Synthesis of majucin-type sesquiterpenes and immobilization and visualization of quorum sensing signaling molecules. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Grundler, Verena. Investigation of the toxicity of cyanobacterial peptides by chemical biology approaches. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Grundler, Verena and Gademann, Karl. (2014) Direct arginine modification in native peptides and application to chemical probe development. ACS medicinal chemistry letters, Vol. 5, H. 12. pp. 1290-1295.

Kohler, Esther and Grundler, Verena and Häussinger, Daniel and Kurmayer, Rainer and Gademann, Karl and Pernthaler, Jakob and Blom, Judith F. . (2014) The toxicity and enzyme activity of a chlorine and sulfate containing aeruginosin isolated from a non-microcystin-producing Planktothrix strain. Harmful Algae, 39. pp. 154-160.

Portmann, Cyril and Sieber, Simon and Wirthensohn, Silvan and Blom, Judith F. and Da Silva, Laeticia and Baudat, Emilie and Kaiser, Marcel and Brun, Reto and Gademann, Karl. (2014) Balgacyclamides, antiplasmodial heterocyclic peptides from Microcystis aeruguinosa EAWAG 251. Journal of natural products, Vol. 77, H. 3. pp. 557-562.

2013

Burch, Patrick. Synthesis, biological evaluation and surface applications of neuritogenic compounds. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Gomes, José and Grunau, Alexander and Lawrence, Adrien K. and Eberl, Leo and Gademann, Karl. (2013) Bioinspired surfaces against bacterial infections. Chimia, 67 (4). pp. 275-278.

Gomes, José and Grunau, Alexander and Lawrence, Adrien K. and Eberl, Leo and Gademann, Karl. (2013) Bioinspired, releasable quorum sensing modulators. Chemical Communications, 49 (2). pp. 155-157.

Gomes, José and Huber, Natalie and Grunau, Alexander and Eberl, Leo and Gademann, Karl. (2013) Fluorescent Labeling Agents for Quorum-Sensing Receptors (FLAQS) in Live Cells. Chemistry: a European journal, Vol. 19, H. 30. pp. 9766-9770.

Hoecker, Johannes. Stereoselective total syntheses of piericidins, the neuritogenic steroid withanolide A and the development of photolabile surface anchors. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Hoecker, Johannes and Gademann, Karl. (2013) Enantioselective Total Syntheses and Absolute Configuration of JBIR-02 and Mer-A2026B. Organic letters, Vol. 15, H. 3 , S. 670–673.

Hoecker, Johannes and Liffert, Raphael and Burch, Patrick and Wehlauch, Robin and Gademann, Karl. (2013) Caged retinoids as photoinducible activators : implications for cell differentiation and neurite outgrowth. Organic & biomolecular chemistry, Vol. 11, H. 20. p. 3314.

Liffert, Raphael and Hoecker, Johannes and Jana, Chandan K. and Woods, Tom M. and Burch, Patrick and Jessen, Henning J. and Neuburger, Markus and Gademann, Karl. (2013) Withanolide A: synthesis and structural requirements for neurite outgrowth. Chemical science, Vol. 4, H. 7. pp. 2851-2857.

Makhlouf Brahmi, Malika and Portmann, Cyril and D`Ambrosio, Danilo and Woods, Tom M. and Banfi, Damiano and Reichenbach, Patrick and Da Silva, Laeticia and Baudat, Emilie and Turcatti, Gerardo and Lingner, Joachim and Gademann, Karl. (2013) Telomerase Inhibitors from Cyanobacteria : Isolation and Synthesis of Sulfoquinovosyl Diacylglycerols from Microcystis aeruguinosaPCC 7806. Chemistry: a European journal, Vol. 19, H. 14. pp. 4596-4601.

Miyatake-Ondozabal, Hideki and Bannwart, Linda M. and Gademann, Karl. (2013) Enantioselective total synthesis of virosaine A and bubbialidine. Chemical Communications, 49 (19). pp. 1921-1923.

Schmid, Fabian and Jessen, Henning J. and Burch, Patrick and Gademann, Karl. (2013) Truncated militarinone fragments identified by total chemical synthesis induce neurite outgrowth. MedChemComm , 4 (1). pp. 135-139.

Thommen, Christophe and Jana, Chandan Kumar and Neuburger, Markus and Gademann, Karl. (2013) Syntheses of Taiwaniaquinone F and Taiwaniaquinol A via an Unusual Remote C-H Functionalization. Organic letters, Vol. 15, H. 6. pp. 1390-1393.

2012

Cantó, Carles and Houtkooper, Riekelt H. and Pirinen, Eija and Youn, Dou Y. and Oosterveer, Maaike H. and Cen, Yana and Fernandez-Marcos, Pablo J. and Yamamoto, Hiroyasu and Andreux, Pénélope A. and Cettour-Rose, Philippe and Gademann, Karl and Rinsch, Chris and Schoonjans, Kristina and Sauve, Anthony A. and Auwerx, Johan. (2012) The NAD(+) Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity. Cell metabolism, Vol. 15, H. 6. pp. 838-847.

Elamparuthi, Elangovan and Fellay, Cindy and Neuburger, Markus and Gademann, Karl. (2012) Total Synthesis of Cyrneine A. Angewandte Chemie International Edition, 51 (17). pp. 4071-4073.

Gademann, Karl and Wach, Jean-Yves. (2012) Reduce to the Maximum : Truncated Natural Products as Powerful Modulators of Biological Processes. Synlett, 2012, Vol. 2. pp. 163-170.

Wehlauch, Robin and Hoecker, Johannes and Gademann, Karl. (2012) Nitrocatechols as Tractable Surface Release Systems. ChemPlusChem, 77. pp. 1071-1074.

2011

Gademann, Karl. (2011) Controlling protein transport by small molecules. Current drug targets, Vol. 12, H. 11. pp. 1574-1580.

Gademann, Karl. (2011) Out in the green : biologically active metabolites produced by cyanobacteria. Chimia, 65 (6). pp. 416-419.

Gademann, Karl and Sieber, Simon. (2011) Chemical Interference of Biological Systems with Natural Products. Chimia, 65 (11). pp. 835-838.

Jana, Chandan Kumar and Hoecker, Johannes and Woods, Tom M. and Jessen, Henning J. and Neuburger, Markus and Gademann, Karl. (2011) Synthesis of Withanolide A, Biological Evaluation of Its Neuritogenic Properties, and Studies on Secretase Inhibition. Angewandte Chemie. International edition in English, Vol. 50, H. 36. pp. 8407-8411.

Schumacher, Andreas and Jessen, Henning J. and Schmid, Fabian and Pfaltz, Andreas and Gademann, Karl. (2011) Catalytic Enantioselective Total Synthesis of (+)-Torrubiellone. Organic Letters, 13 (16). pp. 4368-4370.

Schumacher, Andreas and Jessen, Henning J. and Shaw, Trawis and Pfaltz, Andreas and Gademann, Karl. (2011) A Unified Approach for the Stereoselective Total Synthesis of Pyridone Alkaloids and Their Neuritogenic Activity. Angewandte Chemie International Edition, 50 (18). pp. 4222-4226.

2010

Bonazzi, S. and Barbaras, D. and Patiny, L. and Scopelliti, R. and Schneider, P. and Cole, S. T. and Kaiser, M. and Brun, R. and Gademann, K.. (2010) Antimalarial and antitubercular nostocarboline and eudistomin derivatives: Synthesis, in vitro and in vivo biological evaluation. Bioorganic and Medicinal Chemistry, 18 (4). pp. 1464-1476.

Bonazzi, S. and Binaghi, M. and Fellay, C. and Wach, J. Y. and Gademann, K.. (2010) Synthetic Studies on the Sporolides : Exploration of the Enediyne Route. Synthesis, 4. pp. 631-642.

Bonazzi, S. and Eidam, O. and Guttinger, S. and Wach, J. Y. and Zemp, I. and Kutay, U. and Gademann, K.. (2010) Anguinomycins and Derivatives : Total Syntheses, Modeling, and Biological Evaluation of the Inhibition of Nucleocytoplasmic Transport. Journal of the American Chemical Society, 132 (4). pp. 1432-1442.

Gademann, K. and Portmann, C. and Blom, J. F. and Zeder, M. and Juttner, F.. (2010) Multiple Toxin Production in the Cyanobacterium Microcystis : Isolation of the Toxic Protease Inhibitor Cyanopeptolin 1020. Journal of Natural Products, 73 (5). pp. 980-984.

Jana, C. K. and Scopelliti, R. and Gademann, K.. (2010) A Synthetic Entry into the Taiwaniaquinoids Based on a Biogenetic Hypothesis : Total Synthesis of (-)-Taiwaniaquinone H. Chemistry - A European Journal, 16 (26). pp. 7692-7695.

Jana, C. K. and Scopelliti, R. and Gademann, K.. (2010) Connecting C-19 Norditerpenoids to C-20 Diterpenes : Total Syntheses of 6-Hydroxy-5,6-dehydrosugiol, 6-Hydroxysugiol, and Taiwaniaquinone H, and Formal Synthesis of Dichroanone. Synthesis, H. 13. pp. 2223-2232.

Jessen, H. J. and Gademann, K.. (2010) 4-Hydroxy-2-pyridone alkaloids : Structures and synthetic approaches. Natural product reports, Vol. 27, H. 8. pp. 1168-1185.

Jessen, H. J. and Gademann, K.. (2010) Total Synthesis of the Marine Alkaloid Palau'amine. Angewandte Chemie. International edition in English, Vol. 49, H. 17. pp. 2972-2974.

Locher, H. H. and Ritz, D. and Pfaff, P. and Gaertner, M. and Knezevic, A. and Sabato, D. and Schroeder, S. and Barbaras, D. and Gademann, K.. (2010) Dimers of Nostocarboline with Potent Antibacterial Activity. Chemotherapy, 56 (4). pp. 318-324.

Malisova, B. and Tosatti, S. and Textor, M. and Gademann, K. and Zurcher, S.. (2010) Poly(ethylene glycol) Adlayers Immobilized to Metal Oxide Substrates Through Catechol Derivatives : Influence of Assembly Conditions on Formation and Stability. Langmuir, Vol. 26, H. 6. pp. 4018-4026.

Okello, W. and Ostermaier, V. and Portmann, C. and Gademann, K. and Kurmayer, R.. (2010) Spatial isolation favours the divergence in microcystin net production by Microcystis in Ugandan freshwater lakes. Water research, Vol. 44, H. 9. pp. 2803-2814.

Okello, W. and Portmann, C. and Erhard, M. and Gademann, K. and Kurmayer, R.. (2010) Occurrence of Microcystin-Producing Cyanobacteria in Ugandan Freshwater Habitats. Environmental toxicology, Vol. 25, H. 4. pp. 367-380.

Saxer, S. and Pieles, U. and Elsener, M. and Horisberger, M. and Tosatti, S. and Textor, M. and Gademann, K. and Zurcher, S.. (2010) Design of a high-throughput device for screening surface modification protocols. Progress in Organic Coatings, 67 (1). pp. 20-27.

Saxer, S. and Portmann, C. and Tosatti, S. and Gademann, K. and Zurcher, S. and Textor, M.. (2010) Surface Assembly of Catechol-Functionalized Poly(L-lysine)-graft-poly(ethylene glycol) Copolymer on Titanium Exploiting Combined Electrostatically Driven Self-Organization and Blomimetic Strong Adhesion. Macromolecules, Vol. 43, H. 2. pp. 1050-1060.

Wach, J. Y. and Guttinger, S. and Kutay, U. and Gademann, K.. (2010) The cytotoxic styryl lactone goniothalamin is an inhibitor of nucleocytoplasmic transport. Bioorganic & medicinal chemistry letters, Vol. 20, H. 9. pp. 2843-2846.

2009

Wiesner, Markus. Peptides as catalysts for asymmetric 1,4-addition reactions of aldehydes to nitroolefins. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

2008

Buss, Axel Wolfgang. Diastereoselective synthesis of [alpha]-tocopherol. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

2007

Büttiker, Dominik. Cytochromes P450 : from model compounds towards artificial hemoproteins. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Schlatter, Alain. Asymmetric transfer hydrogenation to aromatic and aliphatic ketones catalyzed by ruthenium complexes linked to both faces of [beta]-cyclodextrin. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

2006

Grütter, Christian. Diastereoselektive Synthese von [alpha]-Tocopherol durch eine neue, enzym-ähnliche Chromanol-Zyklisierung. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Sbaragli, Laura. "Radical clock investigation with a metalloporphyrin enzyme model". 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Stettler, Alexandra. Molekularbiologische Affinitätsstudien : neue Anwendungen elektrophoretischer, miniaturisierter Trennsysteme. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Wang, Hao. Ruthenium porphyrin-ß-cyclodextrin complexes as supramolecular enzyme models for regioselective cleavage of carotenoids. 2006, Doctoral Thesis, University of Basel, Faculty of Science.