Items where Division is "05 Faculty of Science > Departement Biozentrum"

2017

Cabernard, Clemens. (2017) Sibling cell size matters. eLife, 6. e24038.

Dixon-Clarke, Sarah E. and Shehata, Saifeldin N. and Krojer, Tobias and Sharpe, Timothy D. and von Delft, Frank and Sakamoto, Kei and Bullock, Alex N.. (2017) Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16. Biochemical Journal, 474 (5). pp. 699-713.

Kapinos, Larisa E. and Huang, Binlu and Rencurel, Chantal and Lim, Roderick Y. H.. (2017) Karyopherins regulate nuclear pore complex barrier and transport function. Journal of Cell Biology, 216 (11). pp. 3609-3624.

Reichert, Heinrich. (2017) How the humble insect brain became a powerful experimental model system. Journal of Comparative Physiology A, 203 (11). pp. 879-889.

Schwarz, Olivia and Bohra, Ali Asgar and Liu, Xinyu and Reichert, Heinrich and VijayRaghavan, Krishnaswamy and Pielage, Jan. (2017) Motor control of Drosophila feeding behavior. eLife, 6. e19892.

Shi, Guojun and Somlo, Diane and Kim, Geun Hyang and Prescianotto-Baschong, Cristina and Sun, Shengyi and Beuret, Nicole and Long, Qiaoming and Rutishauser, Jonas and Arvan, Peter and Spiess, Martin and Qi, Ling. (2017) ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis. Journal of Clinical Investigation, 127 (10). pp. 3897-3912.

9 October 2016

Hsu, Chieh and Jaquet, Vincent and Maleki, Farzaneh and Becskei, Attila. (2016) Contribution of bistability and noise to cell fate transitions determined by feedback opening. Journal of Molecular Biology, 428 (20). pp. 4115-4128.

20 May 2016

Traunmüller, Lisa and Gomez, Andrea M. and Nguyen, Thi-Minh and Scheiffele, Peter. (2016) Control of neuronal synapse specification by a highly dedicated alternative splicing program. Science, 352 (6288). pp. 982-986.

5 November 2015

Baudrimont, Antoine and Becskei, Attila. (2015) Gene regulation: Expression feels two pulses. Nature, 527 (7576). pp. 46-47.

2015

Bosshart, Andreas and Hee, Chee Seng and Bechtold, Matthias and Schirmer, Tilman and Panke, Sven. (2015) Directed Divergent Evolution of a Thermostable D-Tagatose Epimerase towards Improved Activity for Two Hexose Substrates. ChemBioChem, 16 (4). pp. 592-601.

Sprecher, Simon G. and Bernardo-Garcia, F. Javier and van Giesen, Lena and Hartenstein, Volker and Reichert, Heinrich and Neves, Ricardo and Bailly, Xavier and Martinez, Pedro and Brauchle, Michael. (2015) Functional brain regeneration in the acoel worm Symsagittifera roscoffensis. Biology open, 4. pp. 1688-1695.

2014

Bonde, Marie Mi and Voegeli, Sylvia and Baudrimont, Antoine and Séraphin, Bertrand and Becskei, Attila. (2014) Quantification of pre-mRNA escape rate and synergy in splicing. Nucleic acids research, Vol. 42, H. 20. pp. 12847-12860.

Eroglu, Elif and Burkard, Thomas R. and Jiang, Yanrui and Saini, Nidhi and Homem, Catarina C. F. and Reichert, Heinrich and Knoblich, Juergen A.. (2014) SWI/SNF Complex Prevents Lineage Reversion and Induces Temporal Patterning in Neural Stem Cells. Cell, Vol. 156, H. 6. pp. 1259-1273.

Jiang, Yanrui and Reichert, Heinrich. (2014) Maintaining neural stem cell identity in the brain. eLife, Vol. 3 , e5000.

2013

Cabernard, Clemens and Doe, Chris Q.. (2013) Live Imaging of Neuroblast Lineages within Intact Larval Brains in Drosophila. Cold Spring Harbor Protocols, 2013 (10). p. 7.

Manni, Sandro. Structural and functional characterization of the intracellular kinase domain of vascular endothelial growth factor receptor-2. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Québatte, Gabriela and Kitas, Eric and Seelig, Joachim. (2013) riDOM, a cell penetrating peptide : interaction with phospholipid bilayers. BBA - Biochimica et Biophysica Acta, 1838 (3). pp. 968-977.

Stölting, Meline Nogueira Lucena and Ferrari, Stefano and Handschin, Christoph and Becskei, Attila and Provenzano, Maurizio and Sulser, Tullio and Eberli, Daniel. (2013) Myoblasts inhibit prostate cancer growth by paracrine secretion of tumor necrosis factor-α. Journal of Urology, 189 (5). pp. 1952-1959.

2012

Henrich, P. B. and Monnier, C. A. and Halfter, W. and Haritoglou, C. and Strauss, R. W. and Lim, R. Y. H. and Loparic, M.. (2012) Nanoscale topographic and biomechanical studies of the human internal limiting membrane. Investigative ophthalmology & visual science, Vol. 53. pp. 2561-2570.

Hsu, Chieh and Scherrer, Simone and Buetti-Dinh, Antoine and Ratna, Prasuna and Pizzolato, Julia and Jaquet, Vincent and Becskei, Attila. (2012) Stochastic signalling rewires the interaction map of a multiple feedback network during yeast evolution. Nature communications, Vol. 3 , 682.

Martin, Georges and Gruber, Andreas R. and Keller, Walter and Zavolan, Mihaela. (2012) Genome-wide Analysis of Pre-mRNA 3′ End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3′ UTR Length. Cell Reports, 1 (6). pp. 753-763.

Stuttfeld, Edward. The structural and functional characterization of the extracellular domain of vascular endothelial growth factor receptors : their role in receptor activation and use as therapeutic targets. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Yuhua, Wang. Identifying the role of Mer receptor tyrosine kinase in glioblastoma multiforme. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

2011

Becskei, Attila and Scherrer, Simone and Kelemen, Janos Z. and Murray, Ann Ehrenhofer. (2011) Modeling of chromosomal epigenetic silencing processes. Transcription, 2 (4). pp. 173-178.

Ratna, Prasuna and Becskei, Attila. (2011) Construction of cis-regulatory input functions of yeast promoters. Methods in Molecular Biology, 734. pp. 45-61.

2010

Kelemen, János Z. and Ratna, Prasuna and Scherrer, Simone and Becskei, Attila. (2010) Spatial epigenetic control of mono- and bistable gene expression. PLoS Biology, 8 (3). e1000332.

Sun, Li and Becskei, Attila. (2010) Systems biology: The cost of feedback control. Nature, 467 (7312). pp. 163-164.

Sürücü, Banu. Regulation of protein kinase B (PKB/Akt) by DNA-dependent protein kinase (DNA-PK) under physiological conditions. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

2009

Becskei, Attila. (2009) Linearization through distortion: a new facet of negative feedback in signalling. Molecular Systems Biology, 5. p. 255.

Buetti-Dinh, Antoine and Ungricht, Rosemarie and Kelemen, János Z. and Shetty, Chetak and Ratna, Prasuna and Becskei, Attila. (2009) Control and signal processing by transcriptional interference. Molecular Systems Biology, 5. p. 300.

Byun, Reine and Becskei, Attila. (2009) Biology inspires engineering. Genome Biology, 10 (11). p. 317.

Chan, Ying Wai and Fava, Luca L. and Uldschmid, Andreas and Schmitz, Michael H. A. and Gerlich, Daniel W. and Nigg, Erich A. and Santamaria, Anna. (2009) Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. The Journal of cell biology, Vol. 185, H. 5. pp. 859-874.

Gaitanos, Thomas N. and Santamaria, Anna and Jeyaprakash, A. Arockia and Wang, Bin and Conti, Elena and Nigg, Erich A.. (2009) Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. The EMBO journal, Vol. 28, H. 10. pp. 1442-1452.

Klein, Ulf R. and Haindl, Markus and Nigg, Erich A. and Muller, Stefan. (2009) RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin. Molecular Biology of the Cell, 20 (1). pp. 410-418.

Plodinec, M. and Loparic, M. and Aebi, U.. (2009) Atomic force microscopy for Biological Imaging and Mechanical testing across Length Scales. In: Live Cell Imaging: A Laboratory Manual. New York, pp. 183-203.

Ratna, Prasuna and Scherrer, Simone and Fleischli, Christoph and Becskei, Attila. (2009) Synergy of repression and silencing gradients along the chromosome. Journal of Molecular Biology, 387 (4). pp. 826-839.

Reiner, Andreas. Conformational dynamics and stability of structured peptides and small proteins. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Schmidt, Thorsten I. and Kleylein-Sohn, Julia and Westendorf, Jens and Le Clech, Mikael and Lavoie, Sébastien B. and Stierhof, York-Dieter and Nigg, Erich A.. (2009) Control of Centriole Length by CPAP and CP110. Current biology, Vol. 19, H. 12. pp. 1005-1011.

2008

Chan, Eunice H. Y. and Santamaria, Anna and Silljé, Herman H. W. and Nigg, Erich A.. (2008) Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora. Chromosoma, Vol. 117, H. 5. pp. 457-469.

Malik, Rainer and Nigg, Erich A. and Körner, Roman. (2008) Comparative conservation analysis of the human mitotic phosphoproteome. Bioinformatics, Vol. 24, H. 12. pp. 1426-1432.

Puschendorf, Mareike. Epigenetic programming of mouse pre-implantation development. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Santamaria, Anna and Nagel, Susanna and Sillje, Herman H. W. and Nigg, Erich A.. (2008) The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle. Current biology, Vol. 18, H. 10. pp. 723-729.

Wang, Bin and Malik, Rainer and Nigg, Erich and Körner, Roman. (2008) Evaluation of the Low-Specificity Protease Elastase for Large-Scale Phosphoproteome Analysis. Analytical chemistry, Vol. 80, no. 24. pp. 9526-9533.

Wang, Lily Hui-Ching and Schwarzbraun, Thomas and Speicher, Michael R. and Nigg, Erich A.. (2008) Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation. Chromosoma, Vol. 117, H. 2. pp. 123-135.

2007

Baumann, Christoph and Körner, Roman and Hofmann, Kay and Nigg, Erich A.. (2007) PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint. Cell, Vol. 128, H. 1. pp. 101-114.

Becskei, Attila and Grusby, Michael J.. (2007) Contribution of IL-12R mediated feedback loop to Th1 cell differentiation. FEBS Letters, 581 (27). pp. 5199-5206.

Duensing, A. and Liu, Y. and Perdreau, S. A. and Kleylein-Sohn, J. and Nigg, E. A. and Duensing, S.. (2007) Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates. Oncogene, Vol. 26, H. 43. pp. 6280-6288.

Elowe, Sabine and Hümmer, Stefan and Uldschmid, Andreas and Li, Xiuling and Nigg, Erich A.. (2007) Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions. Genes & development, Vol. 21, H. 17. pp. 2205-2219.

Graser, Susanne and Stierhof, York-Dieter and Lavoie, Sébastien B. and Gassner, Oliver S. and Lamla, Stefan and Le Clech, Mikael and Nigg, Erich A.. (2007) Cep164, a novel centriole appendage protein required for primary cilium formation. The Journal of cell biology, Vol. 179, H. 2. pp. 321-330.

Graser, Susanne and Stierhof, York-Dieter and Nigg, Erich A.. (2007) Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion. Journal of cell science, Vol. 120, H. 24. pp. 4321-4331.

Hergovich, Alexander and Lamla, Stefan and Nigg, Erich A. and Hemmings, Brian A.. (2007) Centrosome-associated NDR kinase regulates centrosome duplication. Molecular cell, Vol. 25, H. 4. pp. 625-634.

Jeyaprakash, A. Arockia and Klein, Ulf R. and Lindner, Doris and Ebert, Judith and Nigg, Erich A. and Conti, Elena. (2007) Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell, Vol. 131, H. 2. pp. 271-285.

Kleylein-Sohn, Julia and Westendorf, Jens and Le Clech, Mikael and Habedanck, Robert and Stierhof, York-Dieter and Nigg, Erich A.. (2007) Plk4-induced centriole biogenesis in human cells. Developmental cell, Vol. 13, H. 2. pp. 190-202.

Neef, Rüdiger and Gruneberg, Ulrike and Kopajtich, Robert and Li, Xiuling and Nigg, Erich A. and Sillje, Herman and Barr, Francis A.. (2007) Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1. Nature Cell Biology, Vol. 9, H. 4. pp. 436-444.

Nigg, Erich A.. (2007) Centrosome duplication : of rules and licenses. Trends in cell biology, Vol. 17, H. 5. pp. 215-221.

Ray-Gallet, Dominique and Quivy, Jean-Pierre and Silljé, Herman W. W. and Nigg, Erich A. and Almouzni, Geneviève. (2007) The histone chaperone Asf1 is dispensable for direct de novo histone deposition in Xenopus egg extracts. Chromosoma, Vol. 116, H. 5. pp. 487-496.

Santamaria, Anna and Neef, Rüdiger and Eberspächer, Uwe and Eis, Knut and Husemann, Manfred and Mumberg, Dominik and Prechtl, Stefan and Schulze, Volker and Siemeister, Gerhard and Wortmann, Lars and Barr, Francis A. and Nigg, Erich A.. (2007) Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. Molecular Biology of the Cell, 18 (10). pp. 4024-4036.

Thein, Kerstin H. and Kleylein-Sohn, Julia and Nigg, Erich A. and Gruneberg, Ulrike. (2007) Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. The Journal of cell biology, Vol. 178, H. 3. pp. 345-354.

2006

Badouel, Caroline and Körner, Roman and Frank-Vaillant, Marie and Couturier, Anne and Nigg, Erich A. and Tassan, Jean-Pierre. (2006) M-phase MELK activity is regulated by MPF and MAPK. Cell cycle, Vol. 5, no. 8. pp. 883-889.

Chalamalasetty, Ravindra B. and Hümmer, Stefan and Nigg, Erich A. and Silljé, Herman H. W.. (2006) Influence of human Ect2 depletion and overexpression on cleavage furrow formation and abscission. Journal of cell science, Vol. 119, H. 14. pp. 3008-3019.

Goto, Hidemasa and Kiyono, Tohru and Tomono, Yasuko and Kawajiri, Aie and Urano, Takeshi and Furukawa, Koichi and Nigg, Erich A. and Inagaki, Masaki. (2006) Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nature Cell Biology, Vol. 8, H. 2. pp. 180-187.

Gruneberg, Ulrike and Neef, Rüdiger and Li, Xiuling and Chan, Eunice H. Y. and Chalamalasetty, Ravindra B. and Nigg, Erich A. and Barr, Francis A.. (2006) KIF14 and citron kinase act together to promote efficient cytokinesis. The Journal of cell biology, Vol. 172, H. 3. pp. 363-372.

Hanisch, Anja and Silljé, Herman H. W. and Nigg, Erich A.. (2006) Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2. The EMBO journal, Vol. 25, H. 23. pp. 5504-5515.

Hanisch, Anja and Wehner, Anja and Nigg, Erich A. and Silljé, Herman H. W.. (2006) Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting. Molecular Biology of the Cell, 17 (1). pp. 448-459.

Mikolajka, Aleksandra and Yan, Xiumin and Popowicz, Grzegorz M. and Smialowski, Pawel and Nigg, Erich A. and Holak, Tad A.. (2006) Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization. Journal of molecular biology, Vol. 359, H. 4. pp. 863-875.

Nigg, Erich A.. (2006) Cell biology : a licence for duplication. Nature, Vol. 442, H. 7105. pp. 874-875.

Nigg, Erich A.. (2006) Origins and consequences of centrosome aberrations in human cancers. International journal of cancer, Vol. 119, H. 12. pp. 2717-2723.

Nousiainen, Marjaana and Silljé, Herman H. W. and Sauer, Guido and Nigg, Erich A. and Körner, Roman. (2006) Phosphoproteome analysis of the human mitotic spindle. Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, H. 14. pp. 5391-5396.

Sayer, John A. and Otto, Edgar A. and O'Toole, John F. and Nurnberg, Gudrun and Kennedy, Michael A. and Becker, Christian and Hennies, Hans Christian and Helou, Juliana and Attanasio, Massimo and Fausett, Blake V. and Utsch, Boris and Khanna, Hemant and Liu, Yan and Drummond, Iain and Kawakami, Isao and Kusakabe, Takehiro and Tsuda, Motoyuki and Ma, Li and Lee, Hwankyu and Larson, Ronald G. and Allen, Susan J. and Wilkinson, Christopher J. and Nigg, Erich A. and Shou, Chengchao and Lillo, Concepcion and Williams, David S. and Hoppe, Bernd and Kemper, Markus J. and Neuhaus, Thomas and Parisi, Melissa A. and Glass, Ian A. and Petry, Marianne and Kispert, Andreas and Gloy, Joachim and Ganner, Athina and Walz, Gerd and Zhu, Xueliang and Goldman, Daniel and Nurnberg, Peter and Swaroop, Anand and Leroux, Michel R. and Hildebrandt, Friedhelm. (2006) The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nature genetics, Vol. 38, H. 6. pp. 674-681.

Schmidt, Andreas and Rauh, Nadine R. and Nigg, Erich A. and Mayer, Thomas U.. (2006) Cytostatic factor : an activity that puts the cell cycle on hold. Journal of cell science, Vol. 119, H. 7. pp. 1213-1218.

Silljé, Herman H. W. and Nagel, Susanna and Körner, Roman and Nigg, Erich A.. (2006) HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes. Current biology, Vol. 16, H. 8. pp. 731-742.

Silljé, Herman H. W. and Nigg, Erich A.. (2006) Purification of mitotic spindles from cultured human cells. Methods, Vol. 38, no. 1. pp. 25-28.

Tachibana, Kiku-e K. and Nigg, Erich A.. (2006) Geminin regulates multiple steps of the chromosome inheritance cycle. Cell cycle, Vol. 5, no. 2. pp. 151-154.

Yan, Xiumin and Habedanck, Robert and Nigg, Erich A.. (2006) A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. Molecular Biology of the Cell, 17 (2). pp. 634-444.

2005

Acar, Murat and Becskei, Attila and van Oudenaarden, Alexander. (2005) Enhancement of cellular memory by reducing stochastic transitions. Nature, 435 (7039). pp. 228-232.

Bahe, Susanne and Stierhof, York-Dieter and Wilkinson, Christopher J. and Leiss, Florian and Nigg, Erich A.. (2005) Rootletin forms centriole-associated filaments and functions in centrosome cohesion. The Journal of cell biology, Vol. 171, H. 1. pp. 27-33.

Becskei, Attila and Kaufmann, Benjamin B. and van Oudenaarden, Alexander. (2005) Contributions of low molecule number and chromosomal positioning to stochastic gene expression. Nature Genetics, 37 (9). pp. 937-944.

Becskei, Attila and Mattaj, Iain W.. (2005) Quantitative models of nuclear transport. Current Opinion in Cell Biology, 17 (1). pp. 27-34.

Casenghi, Martina and Barr, Francis A. and Nigg, Erich A.. (2005) Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome. Journal of cell science, Vol. 118, H. 21. pp. 5101-5108.

Chan, Eunice H. Y. and Nousiainen, Marjaana and Chalamalasetty, Ravindra B. and Schäfer, Anja and Nigg, Erich A. and Silljé, Herman H. W.. (2005) The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene, Vol. 24, H. 12. pp. 2076-2086.

Fabbro, Megan and Zhou, Bin-Bing and Takahashi, Mikiko and Sarcevic, Boris and Lal, Preeti and Graham, Mark E. and Gabrielli, Brian G. and Robinson, Phillip J. and Nigg, Erich A. and Ono, Yoshitaka and Khanna, Kum Kum. (2005) Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Developmental cell, Vol. 9, H. 4. pp. 477-488.

Guarguaglini, Giulia and Duncan, Peter I. and Stierhof, York D. and Holmström, Tim and Duensing, Stefan and Nigg, Erich A.. (2005) The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles. Molecular Biology of the Cell, 16 (3). pp. 1095-1107.

Habedanck, Robert and Stierhof, York-Dieter and Wilkinson, Christopher J. and Nigg, Erich A.. (2005) The Polo kinase Plk4 functions in centriole duplication. Nature Cell Biology, Vol. 7, H. 11. pp. 1140-1146.

Ozbudak, Ertugrul M. and Becskei, Attila and van Oudenaarden, Alexander. (2005) A system of counteracting feedback loops regulates Cdc42p activity during spontaneous cell polarization. Developmental Cell, 9 (4). pp. 565-571.

Rapley, Joseph and Baxter, Joanne E. and Blot, Joelle and Wattam, Samantha L. and Casenghi, Martina and Meraldi, Patrick and Nigg, Erich A. and Fry, Andrew M.. (2005) Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases. Molecular and cellular biology, Vol. 25, H. 4. pp. 1309-1324.

Rauh, Nadine R. and Schmidt, Andreas and Bormann, Jenny and Nigg, Erich A. and Mayer, Thomas U.. (2005) Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation. Nature, Vol. 437. pp. 1048-1052.

Sauer, Guido and Körner, Roman and Hanisch, Anja and Ries, Albert and Nigg, Erich A. and Silljé, Herman H. W.. (2005) Proteome analysis of the human mitotic spindle. Molecular & cellular proteomics, Vol. 4, no. 1. pp. 35-43.

Schmidt, Andreas and Duncan, Peter I. and Rauh, Nadine R. and Sauer, Guido and Fry, Andrew M. and Nigg, Erich A. and Mayer, Thomas U.. (2005) Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity. Genes & development, Vol. 19, H. 4. pp. 502-513.

Tachibana, Kiku-e K. and Gonzalez, Michael A. and Guarguaglini, Giulia and Nigg, Erich A. and Laskey, Ronald A.. (2005) Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects. EMBO reports, Vol. 6, H. 11. pp. 1052-1057.

Yamaguchi, Tomoya and Goto, Hidemasa and Yokoyama, Tomoya and Silljé, Herman and Hanisch, Anja and Uldschmid, Andreas and Takai, Yasushi and Oguri, Takashi and Nigg, Erich A. and Inagaki, Masaki. (2005) Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis. The Journal of cell biology, Vol. 171, H. 3. pp. 431-436.

2004

Barr, Francis A. and Silljé, Herman H. W. and Nigg, Erich A.. (2004) Polo-like kinases and the orchestration of cell division. Nature reviews. Molecular cell biology, Vol. 5, H. 6. pp. 429-440.

Becskei, Attila and Boselli, Monica G. and van Oudenaarden, Alexander. (2004) Amplitude control of cell-cycle waves by nuclear import. Nature Cell Biology , 6 (5). pp. 451-457.

Brecht, Karin. Upregulation of alpha globin promotes apoptotic cell death in the hematopoietic cell line FL5.12. 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Fletcher, Lynda and Cerniglia, George J. and Nigg, Erich A. and Yend, Tim J. and Muschel, Ruth J.. (2004) Inhibition of centrosome separation after DNA damage : a role for Nek2. Radiation research, Vol. 162, H. 2. pp. 128-135.

Gassmann, Reto and Carvalho, Ana and Henzing, Alexander J. and Ruchaud, Sandrine and Hudson, Damien F. and Honda, Reiko and Nigg, Erich A. and Gerloff, Dietlind L. and Earnshaw, William C.. (2004) Borealin : a novel chromosomal passenger required for stability of the bipolar mitotic spindle. The Journal of cell biology, Vol. 166, H. 2. pp. 179-191.

Gruneberg, Ulrike and Neef, Rüdiger and Honda, Reiko and Nigg, Erich A. and Barr, Francis A.. (2004) Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2. The Journal of cell biology, Vol. 166, H. 2. pp. 167-172.

Krämer, Alwin and Mailand, Niels and Lukas, Claudia and Syljuåsen, Randi G. and Wilkinson, Christopher J. and Nigg, Erich A. and Bartek, Jiri and Lukas, Jiri. (2004) Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase. Nature cell biology, Vol. 6, H. 9. pp. 884-891.

Meraldi, Patrick and Honda, Reiko and Nigg, Erich A.. (2004) Aurora kinases link chromosome segregation and cell division to cancer susceptibility. Current opinion in genetics & development, Vol. 14, H. 1. pp. 29-36.

Mishima, Masanori and Pavicic, Visnja and Grüneberg, Ulrike and Nigg, Erich A. and Glotzer, Michael. (2004) Cell cycle regulation of central spindle assembly. Nature, Vol. 430. pp. 908-913.

Sasai, Kaori and Katayama, Hiroshi and Stenoien, David L. and Fujii, Satoshi and Honda, Reiko and Kimura, Masashi and Okano, Yukio and Tatsuka, Masaaki and Suzuki, Fumio and Nigg, Erich A. and Earnshaw, William C. and Brinkley, William R. and Sen, Subrata. (2004) Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motility And The Cytoskeleton, Vol. 59, H. 4. pp. 249-263.

Steensgaard, Peter and Garrè, Massimiliano and Muradore, Ivan and Transidico, Pietro and Nigg, Erich A. and Kitagawa, Katsumi and Earnshaw, William C. and Faretta, Mario and Musacchio, Andrea. (2004) Sgt1 is required for human kinetochore assembly. EMBO reports, Vol. 5, H. 6. pp. 626-631.

Stucke, Volker M. and Baumann, Christoph and Nigg, Erich A.. (2004) Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1. Chromosoma, Vol. 113, H. 1. pp. 1-15.

2003

Andersen, Jens S. and Wilkinson, Christopher J. and Mayor, Thibault and Mortensen, Peter and Nigg, Erich A. and Mann, Matthias. (2003) Proteomic characterization of the human centrosome by protein correlation profiling. Nature, Vol. 426. pp. 570-574.

Becskei, Attila and Mattaj, Iain W.. (2003) The strategy for coupling the RanGTP gradient to nuclear protein export. Proceedings of the National Academy of Sciences of the United States of America, 100 (4). pp. 1717-1722.

Carrera, Pilar and Moshkin, Yuri M. and Gronke, Sebastian and Sillje, Herman H. W. and Nigg, Erich A. and Jackle, Herbert and Karch, Francois. (2003) Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions. Genes & development, Vol. 17, H. 20. pp. 2578-2590.

Casenghi, Martina and Meraldi, Patrick and Weinhart, Ulrike and Duncan, Peter I. and Körner, Roman and Nigg, Erich A.. (2003) Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Developmental cell, Vol. 5, H. 1. pp. 113-125.

Cheng, Kin-Yip and Lowe, Edward D. and Sinclair, John and Nigg, Erich A. and Johnson, Louise N.. (2003) The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex. The EMBO journal, Vol. 22, H. 21. pp. 5757-5768.

Goto, Hidemasa and Yasui, Yoshihiro and Kawajiri, Aie and Nigg, Erich A. and Terada, Yasuhiko and Tatsuka, Masaaki and Nagata, Koh-ichi and Inagaki, Masaki. (2003) Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process. Journal of biological chemistry, Vol. 278, H. 10. pp. 8526-8530.

Groth, Anja and Lukas, Jiri and Nigg, Erich A. and Silljé, Herman H. W. and Wernstedt, Christer and Bartek, Jiri and Hansen, Klaus. (2003) Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint. The EMBO journal, Vol. 22, H. 7. pp. 1676-1687.

Gruneberg, Ulrike and Nigg, Erich A.. (2003) Regulation of cell division : stop the SIN! Trends in cell biology, Vol. 13, H. 4. pp. 159-162.

Honda, Reiko and Körner, Roman and Nigg, Erich A.. (2003) Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Molecular Biology of the Cell, 14 (8). pp. 3325-3341.

Jackman, Mark and Lindon, Catherine and Nigg, Erich A. and Pines, Jonathon. (2003) Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nature Cell Biology, Vol. 5, H. 2. pp. 143-148.

Krause, Darren R. and Jonnalagadda, Jyoti C. and Gatei, Magtouf H. and Sillje, Herman H. W. and Zhou, Bin-Bing and Nigg, Erich A. and Khanna, Kumkum. (2003) Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1. Oncogene, Vol. 22, H. 38. pp. 5927-5937.

Kufer, Thomas A. and Nigg, Erich A. and Silljé, Herman H. W.. (2003) Regulation of Aurora-A kinase on the mitotic spindle. Chromosoma, Vol. 112, H. 4. pp. 159-163.

Neef, Rüdiger and Preisinger, Christian and Sutcliffe, Josephine and Kopajtich, Robert and Nigg, Erich A. and Mayer, Thomas U. and Barr, Francis A.. (2003) Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. The Journal of cell biology, Vol. 162, H. 5. pp. 863-875.

Scholl, Francisco G. and Scheiffele, Peter. (2003) Making connections : cholinesterase-domain proteins in the CNS. Trends in neurosciences, Vol. 26, H. 11. pp. 618-624.

Silljé, Herman H. W. and Nigg, Erich A.. (2003) Capturing polo kinase. Science, Vol. 299, no. 5610. pp. 1190-1191.

2002

Goto, Hidemasa and Yasui, Yoshihiro and Nigg, Erich A. and Inagaki, Masaki. (2002) Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. Genes to cells, Vol. 7, H. 1. pp. 11-17.

Gruneberg, Ulrike and Glotzer, Michael and Gartner, Anton and Nigg, Erich A.. (2002) The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. The Journal of cell biology, Vol. 158, H. 5. pp. 901-914.

Heitlinger, E. and Peter, M. and Lustig, A. and Villiger, W. and Nigg, E. A. and Aebi, U.. (2002) The role of the head and tail domain in lamin structure and assembly : analysis of bacterially expressed chicken lamin A and truncated B2 lamins. Journal of structural biology, Vol. 108, H. 1. pp. 74-89.

Kelm, Olaf and Wind, Mathias and Lehmann, Wolf D. and Nigg, Erich A.. (2002) Cell cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1. Journal of biological chemistry, Vol. 277, H. 28. pp. 25247-25256.

Kufer, Thomas A. and Silljé, Herman H. W. and Körner, Roman and Gruss, Oliver J. and Meraldi, Patrick and Nigg, Erich A.. (2002) Human TPX2 is required for targeting Aurora-A kinase to the spindle. The Journal of cell biology, Vol. 158, H. 4. pp. 617-623.

Louis, Matthieu and Becskei, Attila. (2002) Binary and graded responses in gene networks. Science Signaling, 2002 (143). e33.

Martin-Lluesma, Silvia and Stucke, Volker M. and Nigg, Erich A.. (2002) Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science, Vol. 297, no. 5590. pp. 2267-2270.

Mayor, Thibault and Hacker, Ulrike and Stierhof, York-Dieter and Nigg, Erich A.. (2002) The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles. Journal of cell science, Vol. 115, H. 16. pp. 3275-3284.

Mello, Jill A. and Silljé, Herman H. W. and Roche, Daniele M. J. and Kirschner, Doris B. and Nigg, Erich A. and Almouzni, Geneviève. (2002) Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. EMBO reports, Vol. 3, H. 4. pp. 329-334.

Meraldi, P. and Nigg, E. A.. (2002) The centrosome cycle. FEBS letters, Vol. 521, H. 1-3. pp. 9-13.

Meraldi, Patrick and Honda, Reiko and Nigg, Erich A.. (2002) Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. The EMBO journal, Vol. 21, H. 4. pp. 483-492.

Nigg, Erich A.. (2002) Centrosome aberrations : cause or consequence of cancer progression? Nature reviews. Cancer, Vol. 2, H. 11. pp. 815-825.

Stucke, Volker M. and Silljé, Herman H. W. and Arnaud, Lionel and Nigg, Erich A.. (2002) Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication. The EMBO journal, Vol. 21, H. 7. pp. 1723-1732.

Sumara, Izabela and Vorlaufer, Elisabeth and Stukenberg, P. Todd and Kelm, Olaf and Redemann, Norbert and Nigg, Erich A. and Peters, Jan-Michael. (2002) The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Molecular cell, Vol. 9, H. 3. pp. 515-525.

Wind, Mathias and Kelm, Olaf and Nigg, Erich A. and Lehmann, Wolf D.. (2002) Identification of phosphorylation sites in the polo-like kinases Plx1 and Plk1 by a novel strategy based on element and electrospray high resolution mass spectrometry. Proteomics, Vol. 2, H. 11. pp. 1516-1523.

2001

Araújo, S. J. and Nigg, E. A. and Wood, R. D.. (2001) Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome. Molecular and cellular biology, Vol. 21, H. 7. pp. 2281-2291.

Becskei, A. and Séraphin, B. and Serrano, L.. (2001) Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion. The EMBO Journal, 20 (10). pp. 2528-2535.

Donaldson, M. M. and Tavares, A. A. and Hagan, I. M. and Nigg, E. A. and Glover, D. M.. (2001) The mitotic roles of Polo-like kinase. Journal of cell science, Vol. 114, H. 13. pp. 2357-2358.

Duncan, P. I. and Pollet, N. and Niehrs, C. and Nigg, E. A.. (2001) Cloning and characterization of Plx2 and Plx3, two additional Polo-like kinases from Xenopus laevis. Experimental cell research, Vol. 270, H. 1. pp. 78-87.

Meraldi, P. and Nigg, E. A.. (2001) Centrosome cohesion is regulated by a balance of kinase and phosphatase activities. Journal of cell science, Vol. 114, H. 20. pp. 3749-3757.

Nigg, E. A.. (2001) Cell cycle regulation by protein kinases and phosphatases. Ernst Schering Research Foundation workshop, Vol. 34. pp. 19-46.

Nigg, E. A.. (2001) Mitotic kinases as regulators of cell division and its checkpoints. Nature reviews. Molecular cell biology, Vol. 2, H. 1. pp. 21-32.

Silljé, H. H. and Nigg, E. A.. (2001) Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases. Current biology, Vol. 11, no. 13. pp. 1068-1073.

2000

Becskei, A. and Serrano, L.. (2000) Engineering stability in gene networks by autoregulation. Nature, 405 (6786). pp. 590-593.

Fry, A. M. and Descombes, P. and Twomey, C. and Bacchieri, R. and Nigg, E. A.. (2000) The NIMA-related kinase X-Nek2B is required for efficient assembly of the zygotic centrosome in Xenopus laevis. Journal of cell science, Vol. 113, H. 11. pp. 1973-1984.

Fry, A. M. and Mayor, T. and Nigg, E. A.. (2000) Regulating centrosomes by protein phosphorylation. Current topics in developmental biology, Vol. 49. pp. 291-312.

Mayor, T. and Stierhof, Y. D. and Tanaka, K. and Fry, A. M. and Nigg, E. A.. (2000) The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion. The Journal of cell biology, Vol. 151, H. 4. pp. 837-846.

Pahlavan, G. and Polanski, Z. and Kalab, P. and Golsteyn, R. and Nigg, E. A. and Maro, B.. (2000) Characterization of polo-like kinase 1 during meiotic maturation of the mouse oocyte. Developmental biology, Vol. 220, H. 2. pp. 392-400.

Smits, V. A. and Klompmaker, R. and Arnaud, L. and Rijksen, G. and Nigg, E. A. and Medema, R. H.. (2000) Polo-like kinase-1 is a target of the DNA damage checkpoint. Nature Cell Biology, Vol. 2, H. 9. pp. 672-676.

1999

Degen, Roland. Identification and analysis of "Plasmodium falciparum" genes mediating cytoadherence. 1999, Doctoral Thesis, University of Basel, Faculty of Science.

Fry, A. M. and Arnaud, L. and Nigg, E. A.. (1999) Activity of the human centrosomal kinase, Nek2, depends on an unusual leucine zipper dimerization motif. Journal of biological chemistry, Vol. 274, H. 23. pp. 16304-16310.

Keiser, Jennifer. Pharmacological investigations on current and new drugs for treatment of human African trypanosomiasis. 1999, Doctoral Thesis, University of Basel, Faculty of Science.

Mayor, T. and Meraldi, P. and Stierhof, Y. D. and Nigg, E. A. and Fry, A. M.. (1999) Protein kinases in control of the centrosome cycle. FEBS letters, Vol. 452, H. 1/2. pp. 92-95.

Meraldi, P. and Lukas, J. and Fry, A. M. and Bartek, J. and Nigg, E. A.. (1999) Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nature Cell Biology, Vol. 1, H. 2. pp. 88-93.

Silljé, H. H. and Takahashi, K. and Tanaka, K. and Van Houwe, G. and Nigg, E. A.. (1999) Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication. The EMBO journal, Vol. 18, H. 20. pp. 5691-5702.

Tanaka, K. and Nigg, E. A.. (1999) Cloning and characterization of the murine Nek3 protein kinase, a novel member of the NIMA family of putative cell cycle regulators. Journal of biological chemistry, Vol. 274, H. 19. pp. 13491-13497.

1998

Arnaud, L. and Pines, J. and Nigg, E. A.. (1998) GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes. Chromosoma, Vol. 107, H. 6-7. pp. 424-429.

Blangy, A. and Chaussepied, P. and Nigg, E. A.. (1998) Rigor-type mutation in the kinesin-related protein HsEg5 changes its subcellular localization and induces microtubule bundling. Cell Motility And The Cytoskeleton, Vol. 40, H. 2. pp. 174-182.

Descombes, P. and Nigg, E. A.. (1998) The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts. The EMBO journal, Vol. 17, H. 5. pp. 1328-1335.

Fry, A. M. and Mayor, T. and Meraldi, P. and Stierhof, Y. D. and Tanaka, K. and Nigg, E. A.. (1998) C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2. The Journal of cell biology, Vol. 141, H. 7. pp. 1563-1574.

Fry, A. M. and Meraldi, P. and Nigg, E. A.. (1998) A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. The EMBO journal, Vol. 17, H. 2. pp. 470-481.

Jancsó, G. and Domoki, F. and Sántha, P. and Varga, J. and Fischer, J. and Orosz, K. and Penke, B. and Becskei, Attila and Dux, M. and Tóth, L.. (1998) Beta-amyloid (1-42) peptide impairs blood-brain barrier function after intracarotid infusion in rats. Neuroscience Letters, 253 (2). pp. 139-141.

Marshall, C. J. and Nigg, E. A.. (1998) Oncogenes and cell proliferation cancer genes : lessons from genetics and biochemistry. Current opinion in genetics & development, Vol. 8, H. 1. pp. 11-13.

Nigg, E. A.. (1998) Polo-like kinases : positive regulators of cell division from start to finish. Current opinion in cell biology, Vol. 10, H. 6. pp. 776-783.

1997

Blangy, A. and Arnaud, L. and Nigg, E. A.. (1997) Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150. Journal of biological chemistry, Vol. 272, H. 31. pp. 19418-19424.

Fry, A. M. and Nigg, E. A.. (1997) Characterization of mammalian NIMA-related kinases. Methods in enzymology, vol. 283. pp. 270-282.

Lane, H. A. and Nigg, E. A.. (1997) Cell-cycle control : POLO-like kinases join the outer circle. Trends in cell biology, Vol. 7, H. 2. pp. 63-68.

Mundt, K. E. and Golsteyn, R. M. and Lane, H. A. and Nigg, E. A.. (1997) On the regulation and function of human polo-like kinase 1 (PLK1) : effects of overexpression on cell cycle progression. Biochemical and Biophysical Research Communications, Vol. 239, H. 2. pp. 377-385.

Nigg, E. A.. (1997) Nucleocytoplasmic transport : signals, mechanisms and regulation. Nature, Vol. 386. pp. 779-787.

Tanaka, K. and Parvinen, M. and Nigg, E. A.. (1997) The in vivo expression pattern of mouse Nek2, a NIMA-related kinase, indicates a role in both mitosis and meiosis. Experimental cell research, Vol. 237, H. 2. pp. 264-274.

1996

Adamczewski, J. P. and Rossignol, M. and Tassan, J. P. and Nigg, E. A. and Moncollin, V. and Egly, J. M.. (1996) MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH. The EMBO journal, Vol. 15, H. 8. pp. 1877-1884.

Gold, M. O. and Tassan, J. P. and Nigg, E. A. and Rice, A. P. and Herrmann, C. H.. (1996) Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8. Nucleic Acids Research, 24 (19). pp. 3771-3777.

Golsteyn, R. M. and Lane, H. A. and Mundt, K. E. and Arnaud, L. and Nigg, E. A.. (1996) The family of polo-like kinases. Progress in cell cycle research, Vol. 2. pp. 107-114.

Lane, H. A. and Nigg, E. A.. (1996) Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes. The Journal of cell biology, Vol. 135, H. 6. pp. 1701-1713.

Leclerc, V. and Tassan, J. P. and O'Farrell, P. H. and Nigg, E. A. and Léopold, P.. (1996) Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II. Molecular Biology of the Cell, 7 (4). pp. 505-513.

Nigg, E. A.. (1996) Cyclin-dependent kinase 7 : at the cross-roads of transcription, DNA repair and cell cycle control? Current opinion in cell biology, Vol. 8, H. 3. pp. 312-317.

Nigg, E. A. and Blangy, A. and Lane, H. A.. (1996) Dynamic changes in nuclear architecture during mitosis : on the role of protein phosphorylation in spindle assembly and chromosome segregation. Experimental cell research, Vol. 229, H. 2. pp. 174-180.

1995

Blangy, A. and Lane, H. A. and d'Hérin, P. and Harper, M. and Kress, M. and Nigg, E. A.. (1995) Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell, Vol. 83, H. 7. pp. 1159-1169.

Devault, A. and Martinez, A. M. and Fesquet, D. and Labbé, J. C. and Morin, N. and Tassan, J. P. and Nigg, E. A. and Cavadore, J. C. and Dorée, M.. (1995) MAT1 ('menage à trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK. The EMBO journal, Vol. 14, H. 20. pp. 5027-5036.

Fry, A. M. and Nigg, E. A.. (1995) Cell cycle : the NIMA kinase joins forces with Cdc2. Current biology, Vol. 5, H. 10. pp. 1122-1125.

Fry, A. M. and Schultz, S. J. and Bartek, J. and Nigg, E. A.. (1995) Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homolog of the mitotic regulator NIMA of Aspergillus nidulans. Journal of biological chemistry, Vol. 270 , no. 21. pp. 12899-12905.

Gallant, P. and Fry, A. M. and Nigg, E. A.. (1995) Protein kinases in the control of mitosis : focus on nucleocytoplasmic trafficking. Journal of cell science. Supplement, 19. pp. 21-28.

Golsteyn, R. M. and Mundt, K. E. and Fry, A. M. and Nigg, E. A.. (1995) Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function. The Journal of cell biology, Vol. 129, H. 6. pp. 1617-1628.

Nigg, E. A.. (1995) Cyclin-dependent protein kinases : key regulators of the eukaryotic cell cycle. Bioessays, Vol. 17, H. 6. pp. 471-480.

Ossipow, V. and Tassan, J. P. and Nigg, E. A. and Schibler, U.. (1995) A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation. Cell, Vol. 83, H. 1. pp. 137-146.

Tassan, J. P. and Jaquenoud, M. and Fry, A. M. and Frutiger, S. and Hughes, G. J. and Nigg, E. A.. (1995) In vitro assembly of a functional human CDK7-cyclin H complex requires MAT1, a novel 36 kDa RING finger protein. The EMBO journal, Vol. 14, H. 22. pp. 5608-5617.

Tassan, J. P. and Jaquenoud, M. and Léopold, P. and Schultz, S. J. and Nigg, E. A.. (1995) Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C. Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, H. 19. pp. 8871-8875.

Zucca, E. and Nigg, E. A.. (1995) Cell cycle regulation and the function of cancer genes. Annals of oncology, Vol. 6, no. 10. pp. 975-978.

1994

Gallant, P. and Nigg, E. A.. (1994) Identification of a novel vertebrate cyclin : cyclin B3 shares properties with both A- and B-type cyclins. The EMBO journal, Vol. 13, H. 3. pp. 595-605.

Golsteyn, R. M. and Schultz, S. J. and Bartek, J. and Ziemiecki, A. and Ried, T. and Nigg, E. A.. (1994) Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5. Journal of cell science, Vol. 107, H. 6. pp. 1509-1517.

Hennekes, H. and Nigg, E. A.. (1994) The role of isoprenylation in membrane attachment of nuclear lamins : a single point mutation prevents proteolytic cleavage of the lamin A precursor and confers membrane binding properties. Journal of cell science, Vol. 107, H. 4. pp. 1019-1029.

Mäkelä, T. P. and Tassan, J. P. and Nigg, E. A. and Frutiger, S. and Hughes, G. J. and Weinberg, R. A.. (1994) A cyclin associated with the CDK-activating kinase MO15. Nature, Vol. 371. pp. 254-257.

Roy, R. and Adamczewski, J. P. and Seroz, T. and Vermeulen, W. and Tassan, J. P. and Schaeffer, L. and Nigg, E. A. and Hoeijmakers, J. H. and Egly, J. M.. (1994) The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor. Cell, Vol. 79, H. 6. pp. 1093-1101.

Schultz, S. J. and Fry, A. M. and Sütterlin, C. and Ried, T. and Nigg, E. A.. (1994) Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans. Cell growth & differentiation, Vol. 5, H. 6. pp. 625-635.

Tassan, J. P. and Schultz, S. J. and Bartek, J. and Nigg, E. A.. (1994) Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase). The Journal of cell biology, Vol. 127, H. 2. pp. 467-478.

1993

Hennekes, H. and Peter, M. and Weber, K. and Nigg, E. A.. (1993) Phosphorylation on protein kinase C sites inhibits nuclear import of lamin B2. The Journal of cell biology, Vol. 120, H. 6. pp. 1293-1304.

Maridor, G. and Gallant, P. and Golsteyn, R. and Nigg, E. A.. (1993) Nuclear localization of vertebrate cyclin A correlates with its ability to form complexes with cdk catalytic subunits. Journal of cell science, Vol. 106, H. 2. pp. 535-544.

Nigg, E. A.. (1993) Cellular substrates of p34(cdc2) and its companion cyclin-dependent kinases. Trends in cell biology, Vol. 3, H. 9. pp. 296-301.

Nigg, E. A.. (1993) Targets of cyclin-dependent protein kinases. Current opinion in cell biology, Vol. 5, H. 2. pp. 187-193.

Schmidt-Zachmann, M. S. and Dargemont, C. and Kühn, L. C. and Nigg, E. A.. (1993) Nuclear export of proteins : the role of nuclear retention. Cell, Vol. 74, H. 3. pp. 493-504.

Schmidt-Zachmann, M. S. and Nigg, E. A.. (1993) Protein localization to the nucleolus : a search for targeting domains in nucleolin. Journal of cell science, Vol. 105, H. 3. pp. 799-806.

Schultz, S. J. and Nigg, E. A.. (1993) Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans. Cell growth & differentiation, Vol. 4, H. 10. pp. 821-830.

1992

Gallant, P. and Nigg, E. A.. (1992) Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells. The Journal of cell biology, Vol. 117, H. 1. pp. 213-224.

Krek, W. and Maridor, G. and Nigg, E. A.. (1992) Casein kinase II is a predominantly nuclear enzyme. The Journal of cell biology, Vol. 116, H. 1. pp. 43-55.

Krek, W. and Marks, J. and Schmitz, N. and Nigg, E. A. and Simanis, V.. (1992) Vertebrate p34cdc2 phosphorylation site mutants : effects upon cell cycle progression in the fission yeast Schizosaccharomyces pombe. Journal of cell science, Vol. 102, H. 1. pp. 43-53.

Krek, W. and Nigg, E. A.. (1992) Cell cycle regulation of vertebrate p34cdc2 activity: identification of Thr161 as an essential in vivo phosphorylation site. The New Biologist, Vol. 4, no. 4. pp. 323-329.

Nigg, E. A.. (1992) Assembly and cell cycle dynamics of the nuclear lamina. Seminars in cell biology, Vol. 3, H. 4. pp. 245-253.

Nigg, E. A.. (1992) Assembly-disassembly of the nuclear lamina. Current opinion in cell biology, Vol. 4, H. 1. pp. 105-109.

Nigg, E. A. and Gallant, P. and Krek, W.. (1992) Regulation of p34cdc2 protein kinase activity by phosphorylation and cyclin binding. Ciba Foundation symposium, 170. pp. 72-84; discussion 84-96.

Nigg, E. A. and Kitten, G. T. and Vorburger, K.. (1992) Targeting lamin proteins to the nuclear envelope: the role of CaaX box modifications. Biochemical Society transactions, Vol. 20, H. 2. pp. 500-504.

Peter, M. and Chavrier, P. and Nigg, E. A. and Zerial, M.. (1992) Isoprenylation of rab proteins on structurally distinct cysteine motifs. Journal of cell science, Vol. 102, H. 4. pp. 857-865.

Peter, M. and Sanghera, J. S. and Pelech, S. L. and Nigg, E. A.. (1992) Mitogen-activated protein kinases phosphorylate nuclear lamins and display sequence specificity overlapping that of mitotic protein kinase p34cdc2. European journal of biochemistry, Vol. 205, H. 1. pp. 287-294.

Sanghera, J. S. and Peter, M. and Nigg, E. A. and Pelech, S. L.. (1992) Immunological characterization of avian MAP kinases : evidence for nuclear localization. Molecular Biology of the Cell, 3 (7). pp. 775-787.

1991

Bailer, S. M. and Eppenberger, H. M. and Griffiths, G. and Nigg, E. A.. (1991) Characterization of A 54-kD protein of the inner nuclear membrane : evidence for cell cycle-dependent interaction with the nuclear lamina. The Journal of cell biology, Vol. 114, H. 3. pp. 389-400.

Enoch, T. and Peter, M. and Nurse, P. and Nigg, E. A.. (1991) p34cdc2 acts as a lamin kinase in fission yeast. The Journal of cell biology, Vol. 112, H. 5. pp. 797-807.

Heitlinger, E. and Peter, M. and Häner, M. and Lustig, A. and Aebi, U. and Nigg, E. A.. (1991) Expression of chicken lamin B2 in Escherichia coli : characterization of its structure, assembly, and molecular interactions. The Journal of cell biology, Vol. 113, H. 3. pp. 485-495.

Kitten, G. T. and Nigg, E. A.. (1991) The CaaX motif is required for isoprenylation, carboxyl methylation, and nuclear membrane association of lamin B2. The Journal of cell biology, Vol. 113, H. 1. pp. 13-23.

Krek, W. and Nigg, E. A.. (1991) Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle : identification of major phosphorylation sites. The EMBO journal, Vol. 10, H. 2. pp. 305-316.

Krek, W. and Nigg, E. A.. (1991) Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells : evidence for a double block to p34cdc2 kinase activation in vertebrates. The EMBO journal, Vol. 10, H. 11. pp. 3331-3341.

Maridor, G. and Park, W. and Krek, W. and Nigg, E. A.. (1991) Casein kinase II : cDNA sequences, developmental expression, and tissue distribution of mRNAs for alpha, alpha', and beta subunits of the chicken enzyme. Journal of biological chemistry, Vol. 266 , no. 4. pp. 2362-2368.

Nigg, E. A.. (1991) The substrates of the cdc2 kinase. Seminars in cell biology, Vol. 2, H. 4. pp. 261-270.

Nigg, E. A. and Baeuerle, P. A. and Lührmann, R.. (1991) Nuclear import-export : in search of signals and mechanisms. Cell, Vol. 66, H. 1. pp. 15-22.

Nigg, E. A. and Krek, W. and Peter, M.. (1991) Vertebrate cdc2 kinase : its regulation by phosphorylation and its mitotic targets. Cold Spring Harbor Symposia on Quantitative Biology, vol. 56. pp. 539-547.

Pearson, D. and Nigg, E. A. and Nagamine, Y. and Jans, D. A. and Hemmings, B. A.. (1991) Mechanisms of cAMP-mediated gene induction : examination of renal epithelial cell mutants affected in the catalytic subunit of the cAMP-dependent protein kinase. Experimental cell research, Vol. 192, H. 1. pp. 315-318.

Peter, M. and Heitlinger, E. and Häner, M. and Aebi, U. and Nigg, E. A.. (1991) Disassembly of in vitro formed lamin head-to-tail polymers by CDC2 kinase. The EMBO journal, Vol. 10, H. 6. pp. 1535-1544.

Peter, M. and Nigg, E. A.. (1991) Ectopic expression of an A-type lamin does not interfere with differentiation of lamin A-negative embryonal carcinoma cells. Journal of cell science, Vol. 100, H. 3. pp. 589-598.

1990

Griffiths, G. and Hollinshead, R. and Hemmings, B. A. and Nigg, E. A.. (1990) Ultrastructural localization of the regulatory (RII) subunit of cyclic AMP-dependent protein kinase to subcellular compartments active in endocytosis and recycling of membrane receptors. Journal of cell science, Vol. 96, H. 4. pp. 691-703.

Maridor, G. and Krek, W. and Nigg, E. A.. (1990) Structure and developmental expression of chicken nucleolin and NO38 : coordinate expression of two abundant non-ribosomal nucleolar proteins. Biochimica et biophysica acta, Vol. 1049, H. 2. pp. 126-133.

Maridor, G. and Nigg, E. A.. (1990) cDNA sequences of chicken nucleolin/C23 and NO38/B23 : two major nucleolar proteins. Nucleic Acids Research, 18 (5). p. 1286.

Nigg, E. A.. (1990) Mechanisms of signal transduction to the cell nucleus. Advances in cancer research, Vol. 55. pp. 271-310.

Peter, M. and Nakagawa, J. and Dorée, M. and Labbé, J. C. and Nigg, E. A.. (1990) Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase. Cell, Vol. 60, H. 5. pp. 791-801.

Peter, M. and Nakagawa, J. and Dorée, M. and Labbé, J. C. and Nigg, E. A.. (1990) In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase. Cell, Vol. 61, H. 4. pp. 591-602.

1989

Borer, R. A. and Lehner, C. F. and Eppenberger, H. M. and Nigg, E. A.. (1989) Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell, Vol. 56, H. 3. pp. 379-390.

Krek, W. and Nigg, E. A.. (1989) Structure and developmental expression of the chicken CDC2 kinase. The EMBO journal, Vol. 8, H. 10. pp. 3071-3078.

Nakagawa, J. and Kitten, G. T. and Nigg, E. A.. (1989) A somatic cell-derived system for studying both early and late mitotic events in vitro. Journal of cell science, Vol. 94, H. 3. pp. 449-462.

Nigg, E. A.. (1989) The nuclear envelope. Current opinion in cell biology, Vol. 1, H. 3. pp. 435-440.

Peter, M. and Kitten, G. T. and Lehner, C. F. and Vorburger, K. and Bailer, S. M. and Maridor, G. and Nigg, E. A.. (1989) Cloning and sequencing of cDNA clones encoding chicken lamins A and B1 and comparison of the primary structures of vertebrate A- and B-type lamins. Journal of molecular biology, Vol. 208, H. 3. pp. 393-404.

Vorburger, K. and Kitten, G. T. and Nigg, E. A.. (1989) Modification of nuclear lamin proteins by a mevalonic acid derivative occurs in reticulocyte lysates and requires the cysteine residue of the C-terminal CXXM motif. The EMBO journal, Vol. 8, H. 13. pp. 4007-4013.

Vorburger, K. and Lehner, C. F. and Kitten, G. T. and Eppenberger, H. M. and Nigg, E. A.. (1989) A second higher vertebrate B-type lamin : cDNA sequence determination and in vitro processing of chicken lamin B2. Journal of molecular biology, Vol. 208, H. 3. pp. 405-415.

1988

Nigg, E. A.. (1988) Nuclear function and organization : the potential of immunochemical approaches. International review of cytology, Vol. 110. pp. 27-92.

Stick, R. and Angres, B. and Lehner, C. F. and Nigg, E. A.. (1988) The fates of chicken nuclear lamin proteins during mitosis : evidence for a reversible redistribution of lamin B2 between inner nuclear membrane and elements of the endoplasmic reticulum. The Journal of cell biology, Vol. 107, H. 2. pp. 397-406.

1987

Lehner, C. F. and Stick, R. and Eppenberger, H. M. and Nigg, E. A.. (1987) Differential expression of nuclear lamin proteins during chicken development. The Journal of cell biology, Vol. 105, H. 1. pp. 577-587.

1986

Lehner, C. F. and Eppenberger, H. M. and Fakan, S. and Nigg, E. A.. (1986) Nuclear substructure antigens : monoclonal antibodies against components of nuclear matrix preparations. Experimental cell research, Vol. 162, H. 1. pp. 205-219.

Lehner, C. F. and Fürstenberger, G. and Eppenberger, H. M. and Nigg, E. A.. (1986) Biogenesis of the nuclear lamina : in vivo synthesis and processing of nuclear protein precursors. Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, No. 7. pp. 2096-2099.

Lehner, C. F. and Kurer, V. and Eppenberger, H. M. and Nigg, E. A.. (1986) The nuclear lamin protein family in higher vertebrates : identification of quantitatively minor lamin proteins by monoclonal antibodies. Journal of biological chemistry, Vol. 261 , no. 28. pp. 13293-13301.

Nigg, E. A. and Sefton, B. M. and Singer, S. J. and Vogt, P. K.. (1986) Cytoskeletal organization, vinculin-phosphorylation, and fibronectin expression in transformed fibroblasts with different cell morphologies. Virology, Vol. 151, H. 1. pp. 50-65.

Reuter, R. and Lehner, C. F. and Nigg, E. A. and Lührmann, R.. (1986) A monoclonal antibody specific for snRNPs U1 and U2. FEBS letters, Vol. 201, H. 1. pp. 25-30.

1985

Nigg, E. A. and Hilz, H. and Eppenberger, H. M. and Dutly, F.. (1985) Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus. The EMBO journal, Vol. 4, H. 11. pp. 2801-2806.

Nigg, E. A. and Schäfer, G. and Hilz, H. and Eppenberger, H. M.. (1985) Cyclic-AMP-dependent protein kinase type II is associated with the Golgi complex and with centrosomes. Cell, Vol. 41, H. 3. pp. 1039-1051.

1983

Nigg, E. A. and Cooper, J. A. and Hunter, T.. (1983) Immunofluorescent localization of a 39,000-dalton substrate of tyrosine protein kinases to the cytoplasmic surface of the plasma membrane. The Journal of cell biology, Vol. 96, H. 6. pp. 1601-1609.

Papkoff, J. and Nigg, E. A. and Hunter, T.. (1983) The transforming protein of Moloney murine sarcoma virus is a soluble cytoplasmic protein. Cell, Vol. 33, H. 1. pp. 161-172.

1982

Nigg, E. A. and Sefton, B. M. and Hunter, T. and Walter, G. and Singer, S. J.. (1982) Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide. Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, H. 17. pp. 5322-5326.

Nigg, E. A. and Walter, G. and Singer, S. J.. (1982) On the nature of crossreactions observed with antibodies directed to defined epitopes. Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, H. 19. pp. 5939-5943.

Sefton, B. M. and Hunter, T. and Nigg, E. A. and Singer, S. J. and Walter, G.. (1982) Cytoskeletal targets for viral transforming proteins with tyrosine protein kinase activity. Cold Spring Harbor symposia on quantitative biology, Vol. 46. pp. 939-951.

1981

Cherry, R. J. and Nigg, E. A.. (1981) Rotational diffusion of erythrocyte membrane proteins. Progress in clinical and biological research, Vol. 51. pp. 59-77.

1980

Cherry, R. J. and Nigg, E. A. and Beddard, G. S.. (1980) Oligosaccharide motion in erythrocyte membranes investigated by picosecond fluorescence polarization and microsecond dichroism of an optical probe. Proceedings of the National Academy of Sciences of the United States of America, Vol. 77, H. 10. pp. 5899-5903.

Nigg, E. A. and Bron, C. and Girardet, M. and Cherry, R. J.. (1980) Band 3-glycophorin A association in erythrocyte membrane demonstrated by combining protein diffusion measurements with antibody-induced cross-linking. Biochemistry, Vol. 19, H. 9. pp. 1887-1893.

Nigg, E. A. and Cherry, R. J.. (1980) Anchorage of a band 3 population at the erythrocyte cytoplasmic membrane surface : protein rotational diffusion measurements. Proceedings of the National Academy of Sciences of the United States of America, Vol. 77, H. 8. pp. 4702-4706.

Nigg, E. A. and Cherry, R. J. and Bächi, T.. (1980) Influence of influenza and Sendai virus on the rotational mobility of Band 3 proteins in human erythrocyte membranes. Virology, Vol. 107, H. 2. pp. 552-556.

Nigg, E. A. and Gahmberg, C. G. and Cherry, R. J.. (1980) Rotational diffusion of band 3 proteins in membranes from En(a-) and neuraminidase-treated normal human erythrocytes. Biochimica et biophysica acta, Vol. 600, H. 3. pp. 636-642.

1979

Cherry, R. J. and Nigg, E.. (1979) Rotational diffusion of band 3 in the red cell membrane : measurements using triplet probes. Progress in clinical and biological research, vol. 30. pp. 475-481.

Nigg, E. and Cherry, R. J.. (1979) Dimeric association of band 3 in the erythrocyte membrane demonstrated by protein diffusion measurements. Nature, Vol. 277. pp. 493-494.

Nigg, E. and Kessler, M. and Cherry, R. J.. (1979) Labeling of human erythrocyte membranes with eosin probes used for protein diffusion measurements : inhibition of anion transport and photo-oxidative inactivation of acetylcholinesterase. Biochimica et biophysica acta, Vol. 550, H. 2. pp. 328-340.

Nigg, E. A. and Cherry, R. J.. (1979) Influence of temperature and cholesterol on the rotational diffusion of band 3 in the human erythrocyte membrane. Biochemistry, Vol. 18, H. 16. pp. 3457-3465.