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Items where Division is "09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Former Units within Swiss TPH > Microbial Exposure & Childhood Allergies (Braun-Fahrländer)"

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Article

Brick, Tabea and Schober, Yvonne and Böcking, Christian and Pekkanen, Juha and Genuneit, Jon and Loss, Georg and Dalphin, Jean-Charles and Riedler, Josef and Lauener, Roger and Nockher, Wolfgang Andreas and Renz, Harald and Vaarala, Outi and Braun-Fahrländer, Charlotte and von Mutius, Erika and Ege, Markus Johannes and Pfefferle, Petra Ina and Pasture study group, . (2016) Omega-3 fatty acids contribute to the asthma-protective effect of unprocessed cow's milk. Journal of allergy and clinical immunology, 137 (6). pp. 1699-1706.e13.

Loss, Georg J. and Depner, Martin and Hose, Alexander J. and Genuneit, Jon and Karvonen, Anne M. and Hyvärinen, Anne and Roduit, Caroline and Kabesch, Michael and Lauener, Roger and Pfefferle, Petra Ina and Pekkanen, Juha and Dalphin, Jean-Charles and Riedler, Josef and Braun-Fahrländer, Charlotte and von Mutius, Erika and Ege, Markus J. and Pasture Study Group, . (2016) The early development of wheeze : environmental determinants and genetic susceptibility at 17q21. American journal of respiratory and critical care medicine, 193 (8). pp. 889-897.

Bringolf-Isler, Bettina and Mäder, Urs and Dössegger, Alain and Hofmann, Heidi and Puder, Jardena J. and Braun-Fahrländer, Charlotte and Kriemler, Susi. (2015) Regional differences of physical activity and sedentary behaviour in Swiss children are not explained by socio-demographics or the built environment. International journal of public health, 60 (3). pp. 291-300.

Loss, Georg and Depner, Martin and Ulfman, Laurien H. and van Neerven, R. J. Joost and Hose, Alexander J. and Genuneit, Jon and Karvonen, Anne M. and Hyvärinen, Anne and Kaulek, Vincent and Roduit, Caroline and Weber, Juliane and Lauener, Roger and Pfefferle, Petra Ina and Pekkanen, Juha and Vaarala, Outi and Dalphin, Jean-Charles and Riedler, Josef and Braun-Fahrländer, Charlotte and von Mutius, Erika and Ege, Markus J. and Pasture study group, . (2015) Consumption of unprocessed cow's milk protects infants from common respiratory infections. Journal of allergy and clinical immunology, 135 (1). pp. 56-62.e2.

Marenholz, Ingo and Esparza-Gordillo, Jorge and Rüschendorf, Franz and Bauerfeind, Anja and Strachan, David P. and Spycher, Ben D. and Baurecht, Hansjörg and Margaritte-Jeannin, Patricia and Sääf, Annika and Kerkhof, Marjan and Ege, Markus and Baltic, Svetlana and Matheson, Melanie C. and Li, Jin and Michel, Sven and Ang, Wei Q. and McArdle, Wendy and Arnold, Andreas and Homuth, Georg and Demenais, Florence and Bouzigon, Emmanuelle and Söderhäll, Cilla and Pershagen, Göran and de Jongste, Johan C. and Postma, Dirkje S. and Braun-Fahrländer, Charlotte and Horak, Elisabeth and Ogorodova, Ludmila M. and Puzyrev, Valery P. and Bragina, Elena Yu and Hudson, Thomas J. and Morin, Charles and Duffy, David L. and Marks, Guy B. and Robertson, Colin F. and Montgomery, Grant W. and Musk, Bill and Thompson, Philip J. and Martin, Nicholas G. and James, Alan and Sleiman, Patrick and Toskala, Elina and Rodriguez, Elke and Fölster-Holst, Regina and Franke, Andre and Lieb, Wolfgang and Gieger, Christian and Heinzmann, Andrea and Rietschel, Ernst and Keil, Thomas and Cichon, Sven and Nöthen, Markus M. and Pennell, Craig E. and Sly, Peter D. and Schmidt, Carsten O. and Matanovic, Anja and Schneider, Valentin and Heinig, Matthias and Hübner, Norbert and Holt, Patrick G. and Lau, Susanne and Kabesch, Michael and Weidinger, Stefan and Hakonarson, Hakon and Ferreira, Manuel A. R. and Laprise, Catherine and Freidin, Maxim B. and Genuneit, Jon and Koppelman, Gerard H. and Melén, Erik and Dizier, Marie-Hélène and Henderson, A. John and Lee, Young Ae. (2015) Meta-analysis identifies seven susceptibility loci involved in the atopic march. Nature communications, 6. p. 8804.

Orivuori, L. and Mustonen, K. and de Goffau, M. C. and Hakala, S. and Paasela, M. and Roduit, C. and Dalphin, J.-C. and Genuneit, J. and Lauener, R. and Riedler, J. and Weber, J. and von Mutius, E. and Pekkanen, J. and Harmsen, H. J. M. and Vaarala, O. and Pasture Study Group, . (2015) High level of fecal calprotectin at age 2 months as a marker of intestinal inflammation predicts atopic dermatitis and asthma by age 6. Clinical & experimental allergy, Vol. 45, H. 5. pp. 928-939.

Bringolf-Isler, B. and Kriemler, S. and Mäder, U. and Dössegger, A. and Hofmann, H. and Puder, J. J. and Braun-Fahrländer, C.. (2014) Relationship between the objectively-assessed neighborhood area and activity behavior in Swiss youth. Preventive medicine reports, Vol. 1. pp. 14-20.

Burney, P. G. J. and Potts, J. and Kummeling, I. and Mills, E. N. C. and Clausen, M. and Dubakiene, R. and Barreales, L. and Fernandez-Perez, C. and Fernandez-Rivas, M. and Le, T.-M. and Knulst, A. C. and Kowalski, M. L. and Lidholm, J. and Ballmer-Weber, B. K. and Braun-Fahlander, C. and Mustakov, T. and Kralimarkova, T. and Popov, T. and Sakellariou, A. and Papadopoulos, N. G. and Versteeg, S. A. and Zuidmeer, L. and Akkerdaas, J. H. and Hoffmann-Sommergruber, K. and van Ree, R.. (2014) The prevalence and distribution of food sensitization in european adults. Allergy : european journal of allergy and clinical immunology : official journal of the European Academy of Allergology and Clinical Immunology, Vol. 69, H. 3. pp. 365-371.

Depner, Martin and Fuchs, Oliver and Genuneit, Jon and Karvonen, Anne M. and Hyvärinen, Anne and Kaulek, Vincent and Roduit, Caroline and Weber, Juliane and Schaub, Bianca and Lauener, Roger and Kabesch, Michael and Pfefferle, Petra Ina and Frey, Urs and Pekkanen, Juha and Dalphin, Jean-Charles and Riedler, Josef and Braun-Fahrländer, Charlotte and von Mutius, Erika and Ege, Markus J. and Pasture Study Group, . (2014) Clinical and epidemiologic phenotypes of childhood asthma. American journal of respiratory and critical care medicine, Vol. 189, H. 2. pp. 129-138.

Dössegger, Alain and Ruch, Nicole and Jimmy, Gerda and Braun-Fahrländer, Charlotte and Mäder, Urs and Hänggi, Johanna and Hofmann, Heidi and Puder, Jardena J. and Kriemler, Susi and Bringolf-Isler, Bettina. (2014) Reactivity to accelerometer measurement of children and adolescents. Medicine and science in sports and exercise : official journal of the American College of Sports Medicine, Vol. 46, H. 6. pp. 1140-1146.

Frei, Remo and Roduit, Caroline and Bieli, Christian and Loeliger, Susanne and Waser, Marco and Scheynius, Annika and van Hage, Marianne and Pershagen, Göran and Doekes, Gert and Riedler, Josef and von Mutius, Erika and Sennhauser, Felix and Akdis, Cezmi A. and Braun-Fahrländer, Charlotte and Lauener, Roger P. and as part of the Parsifal study team, . (2014) Expression of genes related to anti-inflammatory pathways are modified among farmers' children. PloS one, Vol. 9, H. 3 , e91097.

Horak, Elisabeth and Morass, Bernhard and Ulmer, Hanno and Genuneit, Jon and Braun-Fahrländer, Charlotte and von Mutius, Erika and on behalf of the Gabriel Study Group, . (2014) Prevalence of wheezing and atopic diseases in Austrian schoolchildren in conjunction with urban, rural or farm residence. Wiener klinische Wochenschrift, Jg. 126, H. 17-18. pp. 532-536.

Lluis, Anna and Depner, Martin and Gaugler, Beatrice and Saas, Philippe and Casaca, Vera Isabel and Raedler, Diana and Michel, Sven and Tost, Jorg and Liu, Jing and Genuneit, Jon and Pfefferle, Petra and Roponen, Marjut and Weber, Juliane and Braun-Fahrländer, Charlotte and Riedler, Josef and Lauener, Roger and Vuitton, Dominique Angèle and Dalphin, Jean-Charles and Pekkanen, Juha and von Mutius, Erika and Schaub, Bianca and Protection Against Allergy: Study in Rural Environments Study Gr, . (2014) Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood. Journal of allergy and clinical immunology, 133 (2). pp. 551-559.

Orivuori, Laura and Mustonen, Kirsi and Roduit, Caroline and Braun-Fahrländer, Charlotte and Dalphin, Jean-Charles and Genuneit, Jon and Lauener, Roger and Pfefferle, Petra and Riedler, Josef and Weber, Juliane and von Mutius, Erika and Pekkanen, Juha and Vaarala, Outi and Pasture Study Group, . (2014) Immunoglobulin A and immunoglobulin G antibodies against β-lactoglobulin and gliadin at age 1 associate with immunoglobulin E sensitization at age 6. Pediatric allergy and immunology, Vol. 25, H. 4. pp. 329-337.

Ragettli, Martina S. and Tsai, Ming-Yi and Braun-Fahrländer, Charlotte and de Nazelle, Audrey and Schindler, Christian and Ineichen, Alex and Ducret-Stich, Regina E. and Perez, Laura and Probst-Hensch, Nicole and Künzli, Nino and Phuleria, Harish C.. (2014) Simulation of population-based commuter exposure to NO2 using different air pollution models. International journal of environmental research and public health, Vol. 11, H. 5. pp. 5049-5068.

Roduit, Caroline and Frei, Remo and Depner, Martin and Schaub, Bianca and Loss, Georg and Genuneit, Jon and Pfefferle, Petra and Hyvärinen, Anne and Karvonen, Anne M. and Riedler, Josef and Dalphin, Jean-Charles and Pekkanen, Juha and von Mutius, Erika and Braun-Fahrländer, Charlotte and Lauener, Roger and Pasture study group, . (2014) Increased food diversity in the first year of life is inversely associated with allergic diseases. Journal of allergy and clinical immunology, 133 (4). pp. 1056-1064.

Scholtens, Salome and Postma, Dirkje S. and Moffatt, Miriam F. and Panasevich, Sviatlana and Granell, Raquel and Henderson, A. John and Melén, Erik and Nyberg, Fredrik and Pershagen, Göran and Jarvis, Deborah and Ramasamy, Adaikalavan and Wjst, Matthias and Svanes, Cecilie and Bouzigon, Emmanuelle and Demenais, Florence and Kauffmann, Francine and Siroux, Valérie and von Mutius, Erika and Ege, Markus Johannes and Braun-Fahrländer, Charlotte and Genuneit, Jon and Gabriela study group, and Brunekreef, Bert and Smit, Henriette A. and Wijga, Alet H. and Kerkhof, Marjan and Curjuric, Ivan and Imboden, Medea and Thun, Gian A. and Probst-Hensch, Nicole and Freidin, Maxim B. and Bragina, Elena Iu and Deev, I. A. and Puzyrev, V. P. and Daley, Denise and Park, Julie and Becker, Allan and Chan-Yeung, Moira and Kozyrskyj, Anita L. and Pare, Peter and Marenholz, Ingo and Lau, Susanne and Keil, Thomas and Lee, Young-Ae and Kabesch, Michael and Wijmenga, Cisca and Franke, Lude and Nolte, Ilja M. and Vonk, Judith and Kumar, Ashish and Farrall, Martin and Cookson, William O. C. M. and Strachan, David P. and Koppelman, Gerard H. and Boezen, H. Marike. (2014) Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure. Journal of allergy and clinical immunology, 133 (3). pp. 885-888.

Acevedo, Nathalie and Sääf, Annika and Söderhäll, Cilla and Melén, Erik and Mandelin, Jami and Pietras, Christina Orsmark and Ezer, Sini and Karisola, Piia and Vendelin, Johanna and Gennäs, Gustav Boije Af and Yli-Kauhaluoma, Jari and Alenius, Harri and von Mutius, Erika and Doekes, Gert and Braun-Fahrländer, Charlotte and Riedler, Josef and van Hage, Marianne and D'Amato, Mauro and Scheynius, Annika and Pershagen, Göran and Kere, Juha and Pulkkinen, Ville. (2013) Interaction between Retinoid acid receptor-related Orphan Receptor Alpha (RORA) and Neuropeptide S Receptor 1 (NPSR1) in asthma. PloS one, Vol. 8, H. 4 , e60111.

Bornelöv, Susanne and Sääf, Annika and Melén, Erik and Bergström, Anna and Torabi Moghadam, Behrooz and Pulkkinen, Ville and Acevedo, Nathalie and Orsmark Pietras, Christina and Ege, Markus and Braun-Fahrländer, Charlotte and Riedler, Josef and Doekes, Gert and Kabesch, Michael and van Hage, Marianne and Kere, Juha and Scheynius, Annika and Söderhäll, Cilla and Pershagen, Göran and Komorowski, Jan. (2013) Rule-based models of the interplay between genetic and environmental factors in childhood allergy. PLoS one, Vol. 8, H. 11 , e80080.

Braun-Fahrländer, C.. (2013) Umwelt und Medizin. Therapeutische Umschau : Monatsschrift für praktische Medizin, Vol. 70, H. 12. p. 707.

Braun-Fahrländer, Charlotte. (2013) Mikrobielles Umfeld und allergische Erkrankungen im Kindesalter. Therapeutische Umschau : Monatsschrift für praktische Medizin, Vol. 70, H. 12. pp. 714-719.

Bringolf-Isler, B. and Graf, E. and Waser, M. and Genuneit, J. and von Mutius, E. and Loss, G. and Kriemler, S. and Braun-Fahrländer, C.. (2013) Association of physical activity, asthma, and allergies : a cohort of farming and nonfarming children. Journal of allergy and clinical immunology, 132 (3). pp. 743-746.e4.

Depner, Martin and Ege, Markus J. and Genuneit, Jon and Pekkanen, Juha and Roponen, Marjut and Hirvonen, Maija-Riitta and Dalphin, Jean-Charles and Kaulek, Vincent and Krauss-Etschmann, Susanne and Riedler, Josef and Braun-Fahrländer, Charlotte and Roduit, Caroline and Lauener, Roger and Pfefferle, Petra I. and Weber, Juliane and von Mutius, Erika and Pasture Study Group, . (2013) Atopic sensitization in the first year of life. Journal of allergy and clinical immunology, 131 (3). pp. 781-788.

Genuneit, Jon and Strachan, David P. and Büchele, Gisela and Weber, Juliane and Loss, Georg and Sozanska, Barbara and Boznanski, Andrzej and Horak, Elisabeth and Heederik, Dick and Braun-Fahrländer, Charlotte and von Mutius, Erika and Gabriela study group, . (2013) The combined effects of family size and farm exposure on childhood hay fever and atopy. Pediatric allergy and immunology, Vol. 24, H. 3. pp. 293-298.

MacNeill, S. J. and Sozanska, B. and Danielewicz, H. and Debinska, A. and Kosmeda, A. and Boznanski, A. and Illi, S. and Depner, M. and Strunz-Lehner, C. and Waser, M. and Büchele, G. and Horak, E. and Genuneit, J. and Heederik, D. and Braun-Fahrländer, C. and von Mutius, E. and Cullinan, P. and Gabriela study group, . (2013) Asthma and allergies: is the farming environment (still) protective in Poland? : The GABRIEL Advanced Studies. Allergy : european journal of allergy and clinical immunology : official journal of the European Academy of Allergology and Clinical Immunology, Vol. 68, H. 6. pp. 771-779.

Michel, S. and Busato, F. and Genuneit, J. and Pekkanen, J. and Dalphin, J. C. and Riedler, J. and Mazaleyrat, N. and Weber, J. and Karvonen, A. M. and Hirvonen, M. R. and Braun-Fahrländer, C. and Lauener, R. and von Mutius, E. and Kabesch, M. and Tost, J.. (2013) Farm exposure and time trends in early childhood may influence DNA methylation in genes related to asthma and allergy. Allergy : european journal of allergy and clinical immunology : official journal of the European Academy of Allergology and Clinical Immunology, Vol. 68, H. 3. pp. 355-364.

Mustonen, Kirsi and Orivuori, Laura and Keski-Nisula, Leea and Hyvärinen, Anne and Pfefferle, Petra Ina and Riedler, Josef and Dalphin, Jean-Charles and Genuneit, Jon and Lauener, Roger and Roduit, Caroline and Braun-Fahrländer, Charlotte and Weber, Juliane and Schaub, Bianca and von Mutius, Erika and Pekkanen, Juha and Vaarala, Outi and Pasture Study Group, . (2013) Inflammatory response and IgE sensitization at early age. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Clinical Immunology, Vol. 24, H. 4. pp. 395-401.

Mélen, E. and Granell, R. and Kogevinas, M. and Strachan, D. and Gonzalez, J. R. and Wjst, M. and Jarvis, D. and Ege, M. and Braun-Fahrländer, C. and Genuneit, J. and Horak, E. and Bouzigon, E. and Demenais, F. and Kauffmann, F. and Siroux, V. and Michel, S. and von Berg, A. and Heinzmann, A. and Kabesch, M. and Probst-Hensch, N. M. and Curjuric, I. and Imboden, M. and Rochat, T. and Henderson, J. and Sterne, J. A. C. and McArdle, W. L. and Hui, J. and James, A. L. and Musk, A. W. and Palmer, L. J. and Becker, A. and Kozyrskyj, A. L. and Chan-Young, M. and Park, J. E. and Leung, A. and Daley, D. and Freidin, M. B. and Deev, I. A. and Ogorodova, L. M. and Puzyrev, V. P. and Celedón, J. C. and Brehm, J. M. and Cloutier, M. M. and Canino, G. and Acosta-Pérez, E. and Soto-Quiros, M. and Avila, L. and Bergström, A. and Magnusson, J. and Söderhäll, C. and Kull, I. and Scholtens, S. and Boezen, H. M. and Koppelman, G. H. and Wijga, A. H. and Marenholz, I. and Esparza-Gordillo, J. and Lau, S. and Lee, Y. A. and Standl, M. and Tiesler, C. M. T. and Flexeder, C. and Heinrich, J. and Myers, R. A. and Ober, C. and Nicolae, D. L. and Farrall, M. and Kumar, A. and Moffatt, M. F. and Cookson, Wocm and Lasky-Su, J.. (2013) Genome-wide association study of body mass index in 23,000 individuals with and without asthma. Clinical & experimental allergy, Vol. 43, H. 4. pp. 463-474.

Nwaru, B. I. and Virtanen, S. M. and Alfthan, G. and Karvonen, A. M. and Genuneit, J. and Lauener, R. P. and Dalphin, J.-C. and Hyvärinen, A. and Pfefferle, P. and Riedler, J. and Weber, J. and Roduit, C. and Kaulek, V. and Braun-Fahrländer, C. and von Mutius, E. and Pekkanen, J. and the Pasture study group, . (2013) Serum vitamin E concentrations at 1 year and risk of atopy, atopic dermatitis, wheezing, and asthma in childhood : the PASTURE study. Allergy : european journal of allergy and clinical immunology : official journal of the European Academy of Allergology and Clinical Immunology, Vol. 6, H. 1. pp. 87-94.

Ragettli, M. S. and Corradi, E. and Braun-Fahrländer, C. and Schindler, C. and de Nazelle, A. and Jerrett, M. and Ducret, R. E. and Künzli, N. and Phuleria, H. C.. (2013) Commuter exposure to ultrafine particles in different urban locations, transportation modes and routes. Atmospheric environment, 77. pp. 376-384.

Stöcklin, Laura and Loss, Georg and von Mutius, Erika and Weber, Juliane and Genuneit, Jon and Horak, Elisabeth and Sozanska, Barbara and Danielewicz, Hanna and Cullinan, Paul and Heederick, Dick and Braun-Fahrländer, Charlotte and Gabriel study group, . (2013) Health-related quality of life in rural children living in four European countries : the GABRIEL study. International journal of public health, 58 (3). pp. 355-366.

Holbreich, Mark and Genuneit, Jon and Weber, Juliane and Braun-Fahrländer, Charlotte and Waser, Marco and von Mutius, Erika. (2012) Amish children living in northern Indiana have a very low prevalence of allergic sensitization. Journal of allergy and clinical immunology, 129 (6). pp. 1671-1673.

Loss, G. and Apprich, S. and Kneifel, W. and von Mutius, E. and Genuneit, J. and Braun-Fahrländer, C.. (2012) Short communication: appropriate and alternative methods to determine viable bacterial counts in cow milk samples. Journal of dairy science, Vol. 95, H. 6. pp. 2916-2918.

Braun-Fahrländer, C. and von Mutius, E.. (2011) Response by Charlotte Braun-Fahrländer and Erika von Mutius. Clinical & experimental allergy, Vol. 41, H. 6. p. 910.

Loss, G. and Apprich, S. and Waser, M. and Kneifel, W. and Genuneit, J. and Büchele, G. and Weber, J. and Sozanska, B. and Danielewicz, H. and Horak, E. and van Neerven, R. J. and Heederik, D. and Lorenzen, P. C. and von Mutius, E. and Braun-Fahrländer, C. and Gabriela, study group. (2011) The protective effect of farm milk consumption on childhood asthma and atopy : the GABRIELA study. Journal of allergy and clinical immunology, 128, H. 4 (4). pp. 766-773.

Moffatt, M. F. and Gut, I. G. and Demenais, F. and Strachan, D. P. and Bouzigon, E. and Heath, S. and von Mutius, E. and Farrall, M. and Lathrop, M. and Cookson, W. O. and Imboden, M. and Liu, L. J. and Künzli, N. and Schindler, C. and Rochat, T. and Gerbase, M. and Curjuric, I. and Thun, G. A. and Probst-Hensch, N. and Braun-Fahrländer, C.. (2010) A large-scale, consortium-based genomewide association study of asthma. The New England journal of medicine, Vol. 363, H. 13. pp. 1211-1221.

Ege, Markus Johannes and Frei, Remo and Bieli, Christian and Schram-Bijkerk, Dieneke and Waser, Marco and Benz, Marcus R. and Weiss, Gertraud and Nyberg, Fredrik and van Hage, Marianne and Pershagen, Göran and Brunekreef, Bert and Riedler, Josef and Lauener, Roger and Braun-Fahrländer, Charlotte and von Mutius, Erika and Parsifal Study team, . (2007) Not all farming environments protect against the development of asthma and wheeze in children. Journal of allergy and clinical immunology, 119 (5). pp. 1140-1147.

Riedler, J. and Braun-Fahrländer, C. and Eder, W. and Schreuer, M. and Waser, M. and Maisch, S. and Carr, D. and Schierl, R. and Nowak, D. and von Mutius, E. and Alex Study Team, . (2001) Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey. Lancet, Vol. 358, no. 9288. pp. 1129-1133.

Thesis

Rochat, Mascha K.. Protective and risk factors for childhood asthma in observational birth cohorts : the role of vitamin D and allergic rhinitis. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Roduit, Caroline. Development of atopic dermatitis and its association with prenatal and early life exposures. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Loss, Georg. Investigating the effect of farm milk consumption on childhood asthma and allergies in the context of farming, early life nutrition and innate immunity. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Bringolf-Isler, Kathrin Bettina. Bewegungsverhalten im Alltag : Kinder und Umwelt. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Wanner, Miriam. Evaluation of national interventions to promote physical activity in Switzerland with a focus on internet-based approaches. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

This list was generated on Mon Dec 23 04:07:18 2024 CET.