Moreno, F. and Fowler, A. V. and Hall, M. and Silhavy, T. J. and Zabin, I. and Schwartz, M.. (1980) A signal sequence is not sufficient to lead beta-galactosidase out of the cytoplasm. Nature, Vol. 286. pp. 356-359.
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Official URL: http://edoc.unibas.ch/dok/A5258223
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Abstract
Escherichia coli strains have been constructed in which lacZ, the gene for the cytoplasmic enzyme beta-galactosidase, is fused to lamB, the gene for an outer membrane protein. One such strain produces a beta-galactosidase which remains cytoplasmic even though it possesses the complete signal sequence of the lamB protein precursor at the amino-terminal end.
| Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Growth & Development > Biochemistry (Hall) |
|---|---|
| UniBasel Contributors: | Hall, Michael N. |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Macmillan |
| ISSN: | 0028-0836 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Last Modified: | 22 Mar 2012 14:20 |
| Deposited On: | 22 Mar 2012 13:20 |
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