Items where Division is "05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Infection Biology (Broz)"

2017

Brodmann, Maj and Dreier, Roland F. and Broz, Petr and Basler, Marek. (2017) Francisella requires dynamic type VI secretion system and ClpB to deliver effectors for phagosomal escape. Nature Communications, 8. p. 15853.

Dreier, Roland F.. Innate immune recognition of Salmonella and Francisella : two model intracellular bacterial pathogens. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Meunier, Etienne and Broz, Petr. (2017) Evolutionary Convergence and Divergence in NLR Function and Structure. Trends in Immunology, 38 (10). pp. 744-757.

Wallet, Pierre and Benaoudia, Sacha and Mosnier, Amandine and Lagrange, Brice and Martin, Amandine and Lindgren, Helena and Golovliov, Igor and Michal, Fanny and Basso, Pauline and Djebali, Sophia and Provost, Angelina and Allatif, Omran and Meunier, Etienne and Broz, Petr and Yamamoto, Masahiro and Py, Bénédicte F. and Faudry, Eric and Sjöstedt, Anders and Henry, Thomas. (2017) IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection. PLoS Pathogens, 13 (10). e1006630.

15 August 2016

Sborgi, Lorenzo and Rühl, Sebastian and Mulvihill, Estefania and Pipercevic, Joka and Heilig, Rosalie and Stahlberg, Henning and Farady, Christopher J. and Müller, Daniel J. and Broz, Petr and Hiller, Sebastian. (2016) GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death. The EMBO Journal, 35 (16). pp. 1766-1778.

9 August 2016

Di Micco, Antonia and Frera, Gianluca and Lugrin, Jérôme and Jamilloux, Yvan and Hsu, Erh-Ting and Tardivel, Aubry and De Gassart, Aude and Zaffalon, Léa and Bujisic, Bojan and Siegert, Stefanie and Quadroni, Manfredo and Broz, Petr and Henry, Thomas and Hrycyna, Christine A. and Martinon, Fabio. (2016) AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity. Proceedings of the National Academy of Sciences of the United States of America, 113 (32). E4671-E4680.

August 2016

Broz, Petr. (2016) Inflammasomes: Intracellular detection of extracellular bacteria. Cell research, 26 (8). pp. 859-860.

July 2016

Broz, Petr and Dixit, Vishva M.. (2016) Inflammasomes: mechanism of assembly, regulation and signalling. Nature reviews. Immunology, 16 (7). pp. 407-420.

February 2016

Meunier, Etienne and Broz, Petr. (2016) Interferon-inducible GTPases in cell autonomous and innate immunity. Cellular microbiology, 18 (2). pp. 168-180.

2016

Broz, Petr. (2016) Immune Response: Intracellular pathogens under attack. eLife, 5. e14729.

Broz, Petr. (2016) Inflammasomes in Host Defense and Autoimmunity. Chimia, 70 (12). pp. 853-855.

Dick, Mathias S.. Functional analysis of the macromolecular inflammasome complex. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Dick, Mathias S. and Sborgi, Lorenzo and Rühl, Sebastian and Hiller, Sebastian and Broz, Petr. (2016) ASC filament formation serves as a signal amplification mechanism for inflammasomes. Nature Communications, 7. p. 11929.

Groß, Christina J. and Mishra, Ritu and Schneider, Katharina S. and Médard, Guillaume and Wettmarshausen, Jennifer and Dittlein, Daniela C. and Shi, Hexin and Gorka, Oliver and Koenig, Paul-Albert and Fromm, Stephan and Magnani, Giovanni and Ćiković, Tamara and Hartjes, Lara and Smollich, Joachim and Robertson, Avril A. B. and Cooper, Matthew A. and Schmidt-Supprian, Marc and Schuster, Michael and Schroder, Kate and Broz, Petr and Traidl-Hoffmann, Claudia and Beutler, Bruce and Kuster, Bernhard and Ruland, Jürgen and Schneider, Sabine and Perocchi, Fabiana and Groß, Olaf. (2016) K(+) Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria. Immunity, 45 (4). pp. 761-773.

Ravotti, Francesco and Sborgi, Lorenzo and Cadalbert, Riccardo and Huber, Matthias and Mazur, Adam and Broz, Petr and Hiller, Sebastian and Meier, Beat H. and Böckmann, Anja. (2016) Sequence-specific solid-state NMR assignments of the mouse ASC PYRIN domain in its filament form. Biomolecular NMR Assignments, 10 (1). pp. 107-115.

Rühl, Sebastian and Broz, Petr. (2016) The gasdermin-D pore: Executor of pyroptotic cell death. Oncotarget, 7 (36). pp. 57481-57482.

December 2015

Broz, Petr. (2015) Inflammasome assembly: the wheels are turning. Cell research, 25 (12). pp. 1277-1278.

29 October 2015

Broz, Petr. (2015) Immunology: Caspase target drives pyroptosis. Nature, 526. pp. 642-643.

27 October 2015

Sborgi, Lorenzo and Ravotti, Francesco and Dandey, Venkata Prasad and Dick, Mathias S. and Mazur, Adam and Reckel, Sina and Chami, Mohamed and Scherer, Sebastian and Huber, Matthias and Böckmann, Anja and Egelman, Edward H. and Stahlberg, Henning and Broz, Petr and Meier, Beat H. and Hiller, Sebastian. (2015) Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 112 (43). pp. 13237-13242.

October 2015

Rühl, Sebastian and Broz, Petr. (2015) Caspase-11 activates a canonical NLRP3 inflammasome by promoting K+ efflux. European journal of immunology, 45 (10). pp. 2927-2936.

2015

Meunier, Etienne and Broz, Petr. (2015) Interferon-induced guanylate-binding proteins promote cytosolic lipopolysaccharide detection by caspase-11. DNA and cell biology, Vol. 34, H. 1. pp. 1-5.

Meunier, Etienne and Broz, Petr. (2015) Quantification of Cytosolic vs. Vacuolar Salmonella in Primary Macrophages by Differential Permeabilization. Journal of visualized experiments, H. 101 , e52960.

Meunier, Etienne and Wallet, Pierre and Dreier, Roland F. and Costanzo, Stéphanie and Anton, Leonie and Rühl, Sebastian and Dussurgey, Sébastien and Dick, Mathias S. and Kistner, Anne and Rigard, Mélanie and Degrandi, Daniel and Pfeffer, Klaus and Yamamoto, Masahiro and Henry, Thomas and Broz, Petr. (2015) Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida. Nature immunology, Vol. 16, H. 5. pp. 476-484.

2014

Broz, Petr. (2014) Getting rid of the bad apple : inflammasome-induced extrusion of salmonella-infected enterocytes. Cell host & microbe, Vol. 16, H. 2. pp. 153-155.

Meunier, Etienne and Dick, Mathias S. and Dreier, Roland F. and Schürmann, Nura and Kenzelmann Broz, Daniela and Warming, Søren and Roose-Girma, Merone and Bumann, Dirk and Kayagaki, Nobuhiko and Takeda, Kiyoshi and Yamamoto, Masahiro and Broz, Petr. (2014) Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. Nature, 509 (7500). pp. 366-370.

O'Donnell, Hope and Pham, Oanh H. and Li, Lin-Xi and Atif, Shaikh M. and Lee, Seung-Joo and Ravesloot, Marietta M. and Stolfi, Jessica L. and Nuccio, Sean-Paul and Broz, Petr and Monack, Denise M. and Baumler, Andreas J. and McSorley, Stephen J.. (2014) Toll-like Receptor and Inflammasome Signals Converge to Amplify the Innate Bactericidal Capacity of T Helper 1 Cells. Immunity, Vol. 40, H. 2. pp. 213-224.

2013

Broz, Petr and Monack, Denise M.. (2013) Measuring Inflammasome Activation in Response to Bacterial Infection. Methods in Molecular Biology, 1040. pp. 65-84.

Broz, Petr and Monack, Denise M.. (2013) Newly described pattern recognition receptors team up against intracellular pathogens. Nature reviews. Immunology, Vol. 13, H. 8. pp. 551-652.

Broz, Petr and Monack, Denise M.. (2013) Noncanonical inflammasomes: caspase-11 activation and effector mechanisms. PLoS Pathogens, 9 (2). e1003144.

Juruj, C. and Lelogeais, V. and Pierini, R. and Perret, M. and Py, B. F. and Jamilloux, Y. and Broz, P. and Ader, F. and Faure, M. and Henry, T.. (2013) Caspase-1 activity affects AIM2 speck formation/stability through a negative feedback loop. Frontiers in Cellular and Infection Microbiology, 3. p. 14.

Xiao, Junpeng and Broz, Petr and Puri, Aaron W. and Deu, Edgar and Morell, Montse and Monack, Denise M. and Bogyo, Matthew. (2013) A coupled protein and probe engineering approach for selective inhibition and activity-based probe labeling of the caspases. Journal of the American Chemical Society, Vol. 135, H. 24. pp. 9130-9138.