Items where Division is "05 Faculty of Science > Departement Biozentrum > Structural Biology & Biophysics > Structural Biology (Hiller)"

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Sborgi, Lorenzo and Rühl, Sebastian and Mulvihill, Estefania and Pipercevic, Joka and Heilig, Rosalie and Stahlberg, Henning and Farady, Christopher J. and Müller, Daniel J. and Broz, Petr and Hiller, Sebastian. (2016) GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death. The EMBO Journal, 35 (16). pp. 1766-1778.

Raschle, Thomas and Rios Flores, Perla and Opitz, Christian and Müller, Daniel J. and Hiller, Sebastian. (2016) Monitoring Backbone Hydrogen-Bond Formation in β-Barrel Membrane Protein Folding. Angewandte Chemie. International edition in English, 55 (20). pp. 5952-5955.

Dick, Mathias S. and Sborgi, Lorenzo and Rühl, Sebastian and Hiller, Sebastian and Broz, Petr. (2016) ASC filament formation serves as a signal amplification mechanism for inflammasomes. Nature Communications, 7. p. 11929.

He, Lichun and Sharpe, Timothy and Mazur, Adam and Hiller, Sebastian. (2016) A molecular mechanism of chaperone–client recognition. Science Advances, 2 (11). e1601625.

Ravotti, Francesco and Sborgi, Lorenzo and Cadalbert, Riccardo and Huber, Matthias and Mazur, Adam and Broz, Petr and Hiller, Sebastian and Meier, Beat H. and Böckmann, Anja. (2016) Sequence-specific solid-state NMR assignments of the mouse ASC PYRIN domain in its filament form. Biomolecular NMR Assignments, 10 (1). pp. 107-115.

Zhong, Franklin L. and Mamaï, Ons and Sborgi, Lorenzo and Boussofara, Lobna and Hopkins, Richard and Robinson, Kim and Szeverényi, Ildikó and Takeichi, Takuya and Balaji, Reshmaa and Lau, Aristotle and Tye, Hazel and Roy, Keya and Bonnard, Carine and Ahl, Patricia J. and Jones, Leigh Ann and Baker, Paul and Lacina, Lukas and Otsuka, Atsushi and Fournie, Pierre R. and Malecaze, François and Lane, E. Birgitte and Akiyama, Masashi and Kabashima, Kenji and Connolly, John E. and Masters, Seth L. and Soler, Vincent J. and Omar, Salma Samir and McGrath, John A. and Nedelcu, Roxana and Gribaa, Moez and Denguezli, Mohamed and Saad, Ali and Hiller, Sebastian and Reversade, Bruno. (2016) Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation. Cell, 167 (1). pp. 187-202.e17.

Sborgi, Lorenzo and Ravotti, Francesco and Dandey, Venkata Prasad and Dick, Mathias S. and Mazur, Adam and Reckel, Sina and Chami, Mohamed and Scherer, Sebastian and Huber, Matthias and Böckmann, Anja and Egelman, Edward H. and Stahlberg, Henning and Broz, Petr and Meier, Beat H. and Hiller, Sebastian. (2015) Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 112 (43). pp. 13237-13242.

Thoma, Johannes and Burmann, Björn M. and Hiller, Sebastian and Müller, Daniel J.. (2015) Impact of holdase chaperones Skp and SurA on the folding of β-barrel outer-membrane proteins. Nature structural & molecular biology, 22 (10). pp. 795-802.

Burmann, Björn M. and Hiller, Sebastian. (2015) Chaperones and chaperone-substrate complexes: dynamic playgrounds for NMR spectroscopists. Progress in Nuclear Magnetic Resonance Spectroscopy, 86/87. pp. 41-64.

Arquint, Christian and Gabryjonczyk, Anna-Maria and Imseng, Stefan and Böhm, Raphael and Sauer, Evelyn and Hiller, Sebastian and Nigg, Erich A. and Maier, Timm. (2015) STIL binding to Polo-box 3 of PLK4 regulates centriole duplication. eLife, 4. e07888.

Brahimi-Horn, M. Christiane and Lacas-Gervais, Sandra and Adaixo, Ricardo and Ilc, Karine and Rouleau, Matthieu and Notte, Annick and Dieu, Marc and Michiels, Carine and Voeltzel, Thibault and Maguer-Satta, Véronique and Pelletier, Joffrey and Ilie, Marius and Hofman, Paul and Manoury, Bénédicte and Schmidt, Alexander and Hiller, Sebastian and Pouysségur, Jacques and Mazure, Natalie M.. (2015) Local mitochondrial-endolysosomal microfusion cleaves voltage-dependent anion channel 1 to promote survival in hypoxia. Molecular and cellular biology, Vol. 35, H. 9. pp. 1491-1505.

Burmann, Björn M. and Holdbrook, Daniel A. and Callon, Morgane and Bond, Peter J. and Hiller, Sebastian . (2015) Revisiting the interaction between the chaperone Skp and lipopolysaccharide. Biophysical journal, 108 (6). pp. 1516-1526.

Jakob, Roman P. and Koch, Johanna R. and Burmann, Björn M. and Schmidpeter, Philipp A. M. and Hunkeler, Moritz and Hiller, Sebastian and Schmid, Franz X. and Maier, Timm. (2015) Dimeric structure of the bacterial extracellular foldase PrsA. Journal of Biological Chemistry, 290 (6). pp. 3278-3292.

Maier, Timm and Clantin, Bernard and Gruss, Fabian and Dewitte, Frédérique and Delattre, Anne-Sophie and Jacob-Dubuisson, Françoise and Hiller, Sebastian and Villeret, Vincent. (2015) Conserved Omp85 lid-lock structure and substrate recognition in FhaC. Nature Communications, 6. p. 7452.

Morgado, Leonor and Zeth, Kornelius and Burmann, Björn M. and Maier, Timm and Hiller, Sebastian . (2015) Characterization of the insertase BamA in three different membrane mimetics by solution NMR spectroscopy. Journal of biomolecular NMR, Vol. 61, H. 3-4. pp. 333-345.

Callon, Morgane and Burmann, Björn M. and Hiller, Sebastian . (2014) Structural mapping of a chaperone-substrate interaction surface. Angewandte Chemie. International edition in English, Vol. 53, H. 20. pp. 5069-5072.

Etzkorn, Manuela and Zoonens, Manuel and Catoire, Laurent J. and Popot, Jean-Luc and Hiller, Sebastian . (2014) How amphipols embed membrane proteins : global solvent accessibility and interaction with a flexible protein terminus. The journal of membrane biology, Vol. 247, H. 9-10. pp. 965-970.

Schnarwiler, Felix and Niemann, Moritz and Doiron, Nicholas and Harsman, Anke and Käser, Sandro and Mani, Jan and Chanfon, Astrid and Dewar, Caroline E. and Oeljeklaus, Silke and Jackson, Christopher B. and Pusnik, Mascha and Schmidt, Oliver and Meisinger, Chris and Hiller, Sebastian and Warscheid, Bettina and Schnaufer, Achim C. and Ochsenreiter, Torsten and Schneider, André. (2014) Trypanosomal TAC40 constitutes a novel subclass of mitochondrial β-barrel proteins specialized in mitochondrial genome inheritance. Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, H. 21. pp. 7624-7629.

Burmann, Björn M. and Wang, Congwei and Hiller, Sebastian. (2013) Conformation and dynamics of the periplasmic membrane-protein–chaperone complexes OmpX–Skp and tOmpA–Skp. Nature structural & molecular biology, 20 (11). pp. 1265-1272.

Gruss, Fabian and Zähringer, Franziska and Jakob, Roman P. and Burmann, Björn M. and Hiller, Sebastian and Maier, Timm. (2013) The structural basis of autotransporter translocation by TamA. Nature structural & molecular biology, Vol. 20, no. 11. pp. 1318-1320.

Hiller, Sebastian . (2013) The functional heart of the M2 channel. Biophysical journal, Vol. 104, H. 8. pp. 1639-1640.

Reckel, Sina and Hiller, Sebastian . (2013) Perspectives of Solution NMR Spectroscopy for Structural and Functional Studies of Integral Membrane Proteins. Molecular physics, Vol. 111, H. 7. pp. 843-849.

Burmann, Björn M. and Hiller, Sebastian. (2012) Solution NMR studies of membrane-protein-chaperone complexes. Chimia, 66 (10). pp. 759-763.

Bühler, Marc and Hiller, Sebastian . (2012) Dynamic nature of heterochromatin highlighted by a HP1(Swi6)-dependent gene silencing mechanism. Cell cycle, Vo. 11, H. 21. pp. 3907-3908.

Harsman, Anke and Niemann, Moritz and Pusnik, Mascha and Schmidt, Oliver and Burmann, Björn M. and Hiller, Sebastian and Meisinger, Chris and Schneider, André and Wagner, Richard. (2012) Bacterial origin of a mitochondrial outer membrane protein translocase : new perspectives from comparative single channel electrophysiology. Journal of biological chemistry, Vol. 287, H. 37. pp. 31437-31445.

Huber, Matthias and Böckmann, Anja and Hiller, Sebastian and Meier, Beat H.. (2012) 4D solid-state NMR for protein structure determination. Physical Chemistry, Chemical Physics, 14 (15). pp. 5239-5246.

Keller, Claudia and Adaixo, Ricardo and Stunnenberg, Rieka and Woolcock, Katrina Jane and Hiller, Sebastian and Bühler, Marc. (2012) HP1(Swi6) mediates the recognition and destruction of heterochromatic RNA transcripts. Molecular cell, 47 (2). pp. 215-227.

Markley, John L. and Akutsu, Hideo and Asakura, Tetsuo and Baldus, Marc and Boelens, Rolf and Bonvin, Alexandre and Kaptein, Robert and Bax, Ad and Bezsonova, Irina and Gryk, Michael R. and Hoch, Jeffrey C. and Korzhnev, Dmitry M. and Maciejewski, Mark W. and Case, Dave and Chazin, Walter J. and Cross, Timothy A. and Dames, Sonja and Kessler, Horst and Lange, Oliver and Madl, Tobias and Reif, Bernd and Sattler, Michael and Eliezer, David and Fersht, Alan and Forman-Kay, Julie and Kay, Lewis E. and Fraser, James and Gross, John and Kortemme, Tanja and Sali, Andrej and Fujiwara, Toshimichi and Gardner, Kevin and Luo, Xuelian and Rizo-Rey, Jose and Rosen, Michael and Gil, Roberto R. and Ho, Chien and Rule, Gordon and Gronenborn, Angela M. and Ishima, Rieko and Klein-Seetharaman, Judith and Tang, Pei and van der Wel, Patrick and Xu, Yan and Grzesiek, Stephan and Hiller, Sebastian and Seelig, Joachim and Laue, Ernest D. and Mott, Helen and Nietlispach, Daniel and Barsukov, Igor and Lian, Lu-Yun and Middleton, David and Blumenschein, Tharin and Moore, Geoffrey and Campbell, Iain and Schnell, Jason and Vakonakis, Ioannis John and Watts, Anthony and Conte, Maria R. and Mason, James and Pfuhl, Mark and Sanderson, Mark R. and Craven, Jeremy and Williamson, Michael and Dominguez, Cyril and Roberts, Gordon and Günther, Ulrich and Overduin, Michael and Werner, Joern and Williamson, Philip and Blindauer, Claudia and Crump, Matthew and Driscoll, Paul and Frenkiel, Tom and Golovanov, Alexander and Matthews, Steve and Parkinson, John and Uhrin, Dusan and Williams, Mark and Neuhaus, David and Oschkinat, Hartmut and Ramos, Andres and Shaw, David E. and Steinbeck, Christoph and Vendruscolo, Michele and Vuister, Geerten W. and Walters, Kylie J. and Weinstein, Harel and Wüthrich, Kurt and Yokoyama, Shigeyuki. (2012) In support of the BMRB. Nature Structural and Molecular Biology, 19 (9). pp. 854-860.

Yu, Tsyr-Yan and Raschle, Thomas and Hiller, Sebastian and Wagner, Gerhard. (2012) Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs. Biochimica et biophysica acta. BBA. Biomembranes, Vol. 1818, H. 6. pp. 1562-1569.

Huber, Matthias and Hiller, Sebastian and Schanda, Paul and Ernst, Matthias and Böckmann, Anja and Verel, René and Meier, Beat H.. (2011) A proton-detected 4D solid-state NMR experiment for protein structure determination. ChemPhysChem, 12 (5). pp. 915-918.

Gossert, Alvar D. and Hiller, Sebastian and Fernández, César. (2011) Automated NMR resonance assignment of large proteins for protein-ligand interaction studies. Journal of the American Chemical Society, Vol. 133. pp. 210-213.

Krähenbühl, Barbara and Hiller, Sebastian and Wider, Gerhard. (2011) 4D APSY-HBCB(CG)CDHD experiment for automated assignment of aromatic amino acid side chains in proteins. Journal of biomolecular NMR, Vol. 51. pp. 313-318.

Kräutler, Vincent and Hiller, Sebastian and Hünenberger, Philippe H.. (2010) Residual structure in a peptide fragment of the outer membrane protein X under denaturing conditions: a molecular dynamics study. European biophysics journal, 39 (10). pp. 1421-1432.

Takeuchi, Koh and Frueh, Dominique P. and Sun, Zhen-Yu J. and Hiller, Sebastian and Wagner, Gerhard. (2010) CACA-TOCSY with alternate 13C-12C labeling: a 13Calpha direct detection experiment for mainchain resonance assignment, dihedral angle information, and amino acid type identification. Journal of biomolecular NMR, 47 (1). pp. 55-63.

Hiller, Sebastian and Malia, Thomas J. and Garces, Robert G. and Orekhov, Vladislav Y. and Wagner, Gerhard. (2010) Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1. Biomolecular NMR Assignments, 4 (1). pp. 29-32.

Hiller, Sebastian and Abramson, Jeff and Mannella, Carmen and Wagner, Gerhard and Zeth, Kornelius. (2010) The 3D structures of VDAC represent a native conformation. Trends in biochemical sciences, Vol. 35. pp. 514-521.

Raschle, Thomas and Hiller, Sebastian and Etzkorn, Manuel and Wagner, Gerhard. (2010) Nonmicellar systems for solution NMR spectroscopy of membrane proteins. Current Opinion in Structural Biology, Vol. 20. pp. 471-479.

Raschle, Thomas and Hiller, Sebastian and Yu, Tsyr-Yan and Rice, Amanda J. and Walz, Thomas and Wagner, Gerhard. (2009) Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs. The journal of the American Chemical Society, 131 (49). pp. 17777-17779.

Hiller, Sebastian and Ibraghimov, Ilghis and Wagner, Gerhard and Orekhov, Vladislav Y.. (2009) Coupled decomposition of four-dimensional NOESY spectra. The journal of the American Chemical Society, 131 (36). pp. 12970-12978.

Hiller, Sebastian and Wagner, Gerhard. (2009) The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins. Current opinion in structural biology, 19 (4). pp. 396-401.

Hiller, Sebastian and Arthanari, Haribabu and Wagner, Gerhard. (2009) The T-lock: automated compensation of radio-frequency induced sample heating. Journal of biomolecular NMR, 44 (2). pp. 69-76.

Hiller, Sebastian and Wider, Gerhard and Wüthrich, Kurt. (2008) APSY-NMR with proteins: practical aspects and backbone assignment. Journal of biomolecular NMR, 42 (3). pp. 179-195.

Hiller, Sebastian and Joss, Rosmarie and Wider, Gerhard. (2008) Automated NMR assignment of protein side chain resonances using automated projection spectroscopy (APSY). The journal of the American Chemical Society, 130 (36). pp. 12073-12079.

Hiller, Sebastian and Garces, Robert G. and Malia, Thomas J. and Orekhov, Vladislav Y. and Colombini, Marco and Wagner, Gerhard. (2008) Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Science, 321 (5893). pp. 1206-1210.

Suzuki, Chikako and Garces, Robert G. and Edmonds, Katherine A. and Hiller, Sebastian and Hyberts, Sven G. and Marintchev, Assen and Wagner, Gerhard. (2008) PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains. Proceedings of the National Academy of Sciences of the United States of America, 105 (9). pp. 3274-3279.

Hiller, Sebastian and Wider, Gerhard and Imbach, Lukas L. and Wüthrich, Kurt. (2008) Interactions with hydrophobic clusters in the urea-unfolded membrane protein OmpX. Angewandte Chemie. International edition in English, 47 (5). pp. 977-981.

Etezady-Esfarjani, Touraj and Hiller, Sebastian and Villalba, Cristina and Wüthrich, Kurt. (2007) Cell-free protein synthesis of perdeuterated proteins for NMR studies. Journal of biomolecular NMR, 39 (3). pp. 229-238.

Hiller, Sebastian and Wasmer, Christian and Wider, Gerhard and Wüthrich, Kurt. (2007) Sequence-specific resonance assignment of soluble nonglobular proteins by 7D APSY-NMR spectroscopy. The journal of the American Chemical Society, 129 (35). pp. 10823-10828.

Gossert, Alvar D. and Hiller, Sebastian and Fiorito, Francesco and Wüthrich, Kurt. (2007) NMR assignment of the E. coli type 1 pilus protein FimF. Journal of biomolecular NMR, 38 (2). p. 195.

Fiorito, Francesco and Hiller, Sebastian and Wider, Gerhard and Wüthrich, Kurt. (2006) Automated resonance assignment of proteins: 6D APSY-NMR. Journal of biomolecular NMR, 35 (1). pp. 27-37.

Hiller, Sebastian and Fiorito, Francesco and Wüthrich, Kurt and Wider, Gerhard. (2005) Automated projection spectroscopy (APSY). Proceedings of the National Academy of Sciences of the United States of America, 102 (31). pp. 10876-10881.

Hiller, Sebastian and Wider, Gerhard and Etezady-Esfarjani, Touraj and Horst, Reto and Wüthrich, Kurt. (2005) Managing the solvent water polarization to obtain improved NMR spectra of large molecular structures. Journal of biomolecular NMR, 32 (1). pp. 61-70.

Tafer, Hakim and Hiller, Sebastian and Hilty, Christian and Fernández, César and Wüthrich, Kurt. (2004) Nonrandom structure in the urea-unfolded Escherichia coli outer membrane protein X (OmpX). Biochemistry, 43 (4). pp. 860-869.

Hiller, Sebastian and Kohl, Andreas and Fiorito, Francesco and Herrmann, Thorsten and Wider, Gerhard and Tschopp, Jürg and Grütter, Markus G. and Wüthrich, Kurt. (2003) NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain. Structure, 11 (10). pp. 1199-1205.

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Callon, Morgane. NMR experiments to characterize cellular and molecular mechanisms : from metabolomics to protein biogenesis. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Gruss, Fabian and Hiller, Sebastian and Maier, Timm. (2015) Purification and Bicelle Crystallization for Structure Determination of the E. coli Outer Membrane Protein TamA. Methods in Molecular Biology, 1329. pp. 259-270.

Hiller, Sebastian and Wider, Gerhard. (2012) Automated projection spectroscopy and its applications. Topics in current chemistry, Vol. 316. pp. 21-47.

Hiller Odermatt, Sebastian and Wagner, G.. (2012) Solution NMR Spectroscopy of Integral Membrane Proteins. In: Comprehensive Biophysics, 5. Burlington, pp. 120-138.