Items where Division is "05 Faculty of Science > Departement Biozentrum > Infection Biology > Molecular Microbiology (Dehio)"

2017

González-Prieto, Coral and Gabriel, Richard and Dehio, Christoph and Schmidt, Manfred and Llosa, Matxalen. (2017) The Conjugative Relaxase TrwC Promotes Integration of Foreign DNA in the Human Genome. Applied and Environmental Microbiology, 83 (12). e00207-17.

Harms, Alexander and Segers, Francisca H. I. D. and Quebatte, Maxime and Mistl, Claudia and Manfredi, Pablo and Körner, Jonas and Chomel, Bruno B. and Kosoy, Michael and Maruyama, Soichi and Engel, Philipp and Dehio, Christoph. (2017) Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella. Genome biology and evolution, 9 (3). pp. 761-776.

Riba, Andrea and Emmenlauer, Mario and Chen, Amy and Sigoillot, Frederic and Cong, Feng and Dehio, Christoph and Jenkins, Jeremy and Zavolan, Mihaela. (2017) Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results. Cell Systems, 4 (2). pp. 182-193.e4.

8 May 2016

Casanova, Alain and Low, Shyan H. and Emmenlauer, Mario and Conde-Alvarez, Raquel and Salcedo, Suzana P. and Gorvel, Jean-Pierre and Dehio, Christoph. (2016) Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells. Journal of Visualized Experiments (114). e54263.

2016

Andritschke, Daniel and Dilling, Sabrina and Emmenlauer, Mario and Welz, Tobias and Schmich, Fabian and Misselwitz, Benjamin and Rämö, Pauli and Rottner, Klemens and Kerkhoff, Eugen and Wada, Teiji and Penninger, Josef M. and Beerenwinkel, Niko and Horvath, Peter and Dehio, Christoph and Hardt, Wolf-Dietrich. (2016) A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. PLoS ONE, 11 (9). e0161965.

Harms, Alexander and Stanger, Frédéric Valentin and Dehio, Christoph. (2016) Biological Diversity and Molecular Plasticity of FIC Domain Proteins. Annual Reviews of Microbiology, 70. pp. 341-360.

Stanger, Frédéric V. and Harms, Alexander and Dehio, Christoph and Schirmer, Tilman. (2016) Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin. PLoS One, 11 (9). e0163654.

11 November 2015

Kreibich, Saskia and Emmenlauer, Mario and Fredlund, Jennifer and Rämö, Pauli and Münz, Christian and Dehio, Christoph and Enninga, Jost and Hardt, Wolf-Dietrich. (2015) Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1. Cell host & microbe, 18 (5). pp. 527-537.

21 October 2015

Schmich, Fabian and Szczurek, Ewa and Kreibich, Saskia and Dilling, Sabrina and Andritschke, Daniel and Casanova, Alain and Low, Shyan Huey and Eicher, Simone and Muntwiler, Simone and Emmenlauer, Mario and Rämo, Pauli and Conde-Alvarez, Raquel and von Mering, Christian and Hardt, Wolf-Dietrich and Dehio, Christoph and Beerenwinkel, Niko. (2015) Erratum to: gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens. Genome Biology, 16 (233). p. 1.

7 October 2015

Schmich, Fabian and Szczurek, Ewa and Kreibich, Saskia and Dilling, Sabrina and Andritschke, Daniel and Casanova, Alain and Low, Shyan Huey and Eicher, Simone and Muntwiler, Simone and Emmenlauer, Mario and Rämö, Pauli and Conde-Alvarez, Raquel and von Mering, Christian and Hardt, Wolf-Dietrich and Dehio, Christoph and Beerenwinkel, Niko. (2015) gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens. Genome Biology, 16 (220). pp. 1-12.

April 2015

Siebourg-Polster, Juliane and Mudrak, Daria and Emmenlauer, Mario and Rämö, Pauli and Dehio, Christoph and Greber, Urs and Fröhlich, Holger and Beerenwinkel, Niko. (2015) NEMix: single-cell nested effects models for probabilistic pathway stimulation. PLoS Computational Biology, 11 (4). e1004078.

2015

Kallert, Sandra. Interleukin-33 and vaccine vectors in virus-host balance. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Kühbacher, Andreas and Emmenlauer, Mario and Rämö, Pauli and Kafai, Natasha and Dehio, Christoph and Cossart, Pascale and Pizarro-Cerdá, Javier. (2015) Genome-Wide siRNA Screen Identifies Complementary Signaling Pathways Involved in Listeria Infection and Reveals Different Actin Nucleation Mechanisms during Listeria Cell Invasion and Actin Comet Tail Formation. mBio, 6 (3). e00598-15.

Low, Shyan Huey. Genome-wide RNAi screen reveals host factors involved in "Brucella" infection. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Lu, Yun-Yueh. Modulation of host immune responses by Bartonella effector proteins. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

December 2014

Rämö, Pauli and Drewek, Anna and Arrieumerlou, Cécile and Beerenwinkel, Niko and Ben-Tekaya, Houchaïma and Cardel, Bettina and Casanova, Alain and Conde-Alvarez, Raquel and Cossart, Pascale and Csúcs, Gábor and Eicher, Simone and Emmenlauer, Mario and Greber, Urs and Hardt, Wolf-Dietrich and Helenius, Ari and Kasper, Christoph and Kaufmann, Andreas and Kreibich, Saskia and Kühbacher, Andreas and Kunszt, Peter and Low, Shyan Huey and Mercer, Jason and Mudrak, Daria and Muntwiler, Simone and Pelkmans, Lucas and Pizarro-Cerdá, Javier and Podvinec, Michael and Pujadas, Eva and Rinn, Bernd and Rouilly, Vincent and Schmich, Fabian and Siebourg-Polster, Juliane and Snijder, Berend and Stebler, Michael and Studer, Gabriel and Szczurek, Ewa and Truttmann, Matthias and von Mering, Christian and Vonderheit, Andreas and Yakimovich, Artur and Bühlmann, Peter and Dehio, Christoph. (2014) Simultaneous analysis of large-scale RNAi screens for pathogen entry. BMC Genomics, 15 (1). p. 1162.

2014

Casanva, Alain. RNA interference screening identifies host factors involved in brucella infection. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Franceschini, Andrea and Meier, Roger and Casanova, Alain and Kreibich, Saskia and Daga, Neha and Andritschke, Daniel and Dilling, Sabrina and Rämö, Pauli and Emmenlauer, Mario and Kaufmann, Andreas and Conde-Álvarez, Raquel and Low, Shyan Huey and Pelkmans, Lucas and Helenius, Ari and Hardt, Wolf-Dietrich and Dehio, Christoph and von Mering, Christian. (2014) Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens. Proceedings of the National Academy of Sciences, 111 (12). pp. 4548-4553.

Harms, Alexander. FIC domain toxins are the origin of intra- and inter-kingdom effectors of Bartonella. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Okujava, Rusudan and Guye, Patrick and Lu, Yun-Yueh and Mistl, Claudia and Polus, Florine and Vayssier-Taussat, Muriel and Halin, Cornelia and Rolink, Antonius G. and Dehio, Christoph. (2014) A translocated effector required for bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors. PLoS Pathogens, Vol. 10, H. 6 , e1004187.

Pieles, Kathrin. From FIC to BID : target identification and functional characterization of "Bartonella" effector proteins. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Pieles, Kathrin and Glatter, Timo and Harms, Alexander and Schmidt, Alexander and Dehio, Christoph. (2014) An experimental strategy for the identification of AMPylation targets from complex protein samples. Proteomics, 14 (9). pp. 1048-1052.

Québatte, Maxime. Uncovering the transcriptional control of "Bartonella henselae" host adaptation factors. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Siamer, Sabrina and Dehio, Christoph. (2014) New insights into the role of Bartonella effector proteins in pathogenesis. Current Opinion in Microbiology, Vol. 23C. pp. 80-85.

Stanger, Frédéric V. and Dehio, Christoph and Schirmer, Tilman. (2014) Structure of the N-terminal gyrase B fragment in complex with ADP⋅Pi reveals rigid-body motion induced by ATP hydrolysis. PloS one, Vol. 9, H. 9 , e107289.

Stekhoven, Daniel J. and Omasits, Ulrich and Quebatte, Maxime and Dehio, Christoph and Ahrens, Christian H.. (2014) Proteome-wide identification of predominant subcellular protein localizations in a bacterial model organism. Journal of Proteomics , 99. pp. 123-137.

2013

Alperi, A. and Larrea, D. and Fernández-González, E. and Dehio, C. and Zechner, E. L. and Llosa, M.. (2013) A translocation motif in relaxase TrwC specifically affects recruitment by its conjugative Type IV Secretion System. Journal of Bacteriology, 195 (22). pp. 4999-5006.

Ben-Tekaya, H. and Gorvel, J. P. and Dehio, C.. (2013) Bartonella and Brucella - weapons and strategies for stealth attack. Cold Spring Harbor Perspectives in Medicine, 3 (8). a010231.

Eicher, Simone and Dehio, Christoph. (2013) Systems-level analysis of host-pathogen interaction using RNA interference. New biotechnology, Vol. 30, H. 3. pp. 308-313.

Farhan, M. and Ruusuvuori, P. and Emmenlauer, M. and Rämö, P. and Dehio, C. and Yli-Harja, O.. (2013) Multi-scale Gaussian representation and outline-learning based cell image segmentation. BMC Bioinformatics, Vol. 14, Suppl 10 , S6.

Goepfert, Arnaud and Stanger, Frédéric V. and Dehio, Christoph and Schirmer, Tilman. (2013) Conserved inhibitory mechanism and competent ATP binding mode for adenylyltransferases with fic fold. PLoS one, Vol. 8, H. 5 , e64901.

Okujava, Rusudan. Functional characterization of "Bartonella" effector protein - BepE during "in vivo" and "in vitro" infection. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Omasits, U. and Quebatte, M. and Stekhoven, D. J. and Fortes, C. and Roschitzki, B. and Robinson, M. D. and Dehio, C. and Ahrens, C. H.. (2013) Directed shotgun proteomics guided by saturated RNA-seq identifies a complete expressed prokaryotic proteome. Genome Research, 23. pp. 1916-1927.

Québatte, M. and Dick, M. S. and Kaever, V. and Schmidt, A. and Dehio, C.. (2013) Dual input control : activation of the Bartonella henselae VirB/D4 Type IV secretion system by the stringent sigma factor RpoH1 and the BatR/BatS two component system. Molecular microbiology, Vol. 90, H. 4. pp. 756-775.

Rolain, J. M. and Vayssier-Taussat, M. and Saisongkorh, W. and Merhej, V. and Gimenez, G. and Robert, C. and Le Rhun, D. and Dehio, C. and Raoult, D.. (2013) Partial disruption of translational and posttranslational machinery reshapes growth rates of Bartonella birtlesii. mBio, 4 (2). e00115-13.

2012

Dehio, C. and Berry, C. and Bartenschlager, R.. (2012) Persistent intracellular pathogens. FEMS Microbiology Reviews, 36 (3). p. 513.

Eicher, S. C. and Dehio, C.. (2012) Bartonella entry mechanisms into mammalian host cells. Cellular Microbiology, 14 (8). pp. 1166-1173.

Harms, Alexander and Dehio, Christoph. (2012) Intruders below the Radar : Molecular Pathogenesis of Bartonella spp. Clinical microbiology reviews, Vol. 25, H. 1. pp. 42-78.

Llosa, M. and Schröder, G. and Dehio, C.. (2012) New perspectives into bacterial DNA transfer to human cells. Trends in Microbiology, 20 (8). pp. 355-359.

Lu, Y. Y. and Franz, B. and Truttmann, M. C. and Riess, T. and Gay-Fraret, J. and Faustmann, M. and Kempf, V. A. and Dehio, C.. (2012) Bartonella henselae trimeric autotransporter adhesin BadA expression interferes with effector translocation by the VirB/D4 type IV secretion system. Cellular microbiology, Vol. 15, H. 5 , S. 759–778.

Pulliainen, A. T. and Pieles, K. and Brand, C. S. and Hauert, B. and Böhm, A. and Quebatte, M. and Wepf, A. and Gstaiger, M. and Aebersold, R. and Dessauer, C. W. and Dehio, C.. (2012) Bacterial effector binds host cell adenylyl cyclase to potentiate Gαs-dependent cAMP production. Proceedings of the National Academy of Sciences of the United States of America, 109 (24). pp. 9581-9586.

Pulliainen, Arto Tapio and Dehio, Christoph. (2012) Persistence of Bartonella spp. stealth pathogens : from sub-clinical infections to vasoproliferative tumour formation. FEMS Microbiology Reviews, 36 (3). pp. 563-599.

Rouilly, Vincent and Pujadas, Eva and Hullár, Béla and Balázs, Csaba and Kunszt, Peter and Podvinec, Michael. (2012) iBRAIN2: automated analysis and data handling for RNAi screens. Studies in health technology and informatics, Vol. 175. pp. 205-213.

31 December 2011

Engel, Philipp. A genomic approach to the role of type IV secretion systems in Bartonella host adaption. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

2011

Engel, Philipp and Salzburger, Walter and Liesch, Marius and Chang, Chao-Chin and Maruyama, Soichi and Lanz, Christa and Calteau, Alexandra and Lajus, Aurélie and Médigue, Claudine and Schuster, Stephan C. and Dehio, Christoph. (2011) Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella. PLoS Genetics, 7 (2). e1001296.

Fernández-González, Esther and de Paz, Héctor D. and Alperi, Anabel and Agúndez, Leticia and Faustmann, Marco and Sangari, Félix J. and Dehio, Christoph and Llosa, Matxalen. (2011) Transfer of R388 derivatives by a pathogenesis-associated type IV secretion system into both bacteria and human cells. Journal of bacteriology, Vol. 193, H. 22. pp. 6257-6265.

Mietze, A. and Morick, D. and Kohler, H. and Harrus, S. and Dehio, C. and Nolte, I. and Goethe, R.. (2011) Combined MLST and AFLP typing of Bartonella henselae isolated from cats reveals new sequence types and suggests clonal evolution. Veterinary Microbiology, 148. pp. 238-245.

Palanivelu, D. V. and Goepfert, A. and Meury, M. and Guye, P. and Dehio, C. and Schirmer, T.. (2011) Fic domain catalyzed adenylylation: Insight provided by the structural analysis of the type IV secretion system effector BepA. Protein Science, 20 (3). pp. 492-499.

Schröder, Gunnar and Schuelein, Ralf and Quebatte, Maxime and Dehio, Christoph. (2011) Conjugative DNA transfer into human cells by the VirB/VirD4 type IV secretion system of the bacterial pathogen Bartonella henselae. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 35. pp. 14643-14648.

Truttmann, M. C. and Rhomberg, T. A. and Dehio, C.. (2011) Combined action of the type IV secretion effector proteins BepC and BepF promotes invasome formation of Bartonella henselae on endothelial and epithelial cells. Cellular Microbiology, Vol. 13, H. 2. pp. 284-299.

Truttmann, Matthias C. and Guye, Patrick and Dehio, Christoph. (2011) BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures. PLoS ONE, 6 (10). e25106.

Truttmann, Matthias C. and Misselwitz, Benjamin and Huser, Sonja and Hardt, Wolf-Dietrich and Critchley, David R. and Dehio, Christoph. (2011) Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake. Journal of Cell Science, 124 (21). pp. 3591-3602.

Truttmann, Matthias Christoph. A systematic approach to the molecular and cellular basis of Bartonella henselae-triggered invasome formation. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

2010

Cornils, Hauke. Functional characterization of mammalian NDR kinase deficiency : novel functions and insights into downstream signaling mechanisms. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Quebatte, Maxime and Dehio, Michaela and Tropel, David and Basler, Andrea and Toller, Isabella and Raddatz, Guenter and Engel, Philipp and Huser, Sonja and Schein, Hermine and Lindroos, Hillevi L. and Andersson, Siv G. E. and Dehio, Christoph. (2010) The BatR/BatS two-component regulatory system controls the adaptive response of Bartonella henselae during human endothelial cell infection. Journal of bacteriology, 192 (13). pp. 3352-3367.

Scheidegger, F. and Quebatte, M. and Mistl, C. and Dehio, C.. (2010) The Bartonella henselae VirB/Bep system interferes with vascular endothelial growth factor (VEGF) signalling in human vascular endothelial cells. Cellular Microbiology, 13 (3). pp. 419-431.

Thommen, Daniela Stefanie. Endothelial cells as targets for antigen-specific cytotoxic T lymphocytes. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Vayssier-Taussat, Muriel and Le Rhun, Danielle and Deng, Hong Kuan and Biville, Francis and Cescau, Sandra and Danchin, Antoine and Marignac, Geneviève and Lenaour, Evelyne and Boulouis, Henri Jean and Mavris, Maria and Arnaud, Lionel and Yang, Huanming and Wang, Jing and Quebatte, Maxime and Engel, Philipp and Saenz, Henri and Dehio, Christoph. (2010) The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes. PLoS Pathogens, Vol. 6, H. 6 , e1000946.

Woodward Scott, Rachel. Enhanced transcription of the IFN-alpha inducible gene IFITM3 by means of dynamic promoter demethylation in the presence of the TGF-beta inducible small calcium binding protein S100A2. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

de Paz, Héctor D. and Larrea, Delfina and Zunzunegui, Sandra and Dehio, Christoph and de la Cruz, Fernando and Llosa, Matxalen. (2010) Functional dissection of the conjugative coupling protein TrwB. Journal of bacteriology, 192 (11). pp. 2655-2669.

2009

Chomel, B. B. and Boulouis, H. -J. and Breitschwerdt, E. B. and Kasten, R. W. and Vayssier-Taussat, M. and Birtles, R. J. and Koehler, J. E. and Dehio, C.. (2009) Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors. Veterinary Research, 40 (2). p. 29.

Engel, P. and Dehio, C.. (2009) Genomics of Host-Restricted Pathogens of the Genus Bartonella. Genome dynamics, 6. pp. 158-169.

Llosa, M. and Roy, C. and Dehio, C.. (2009) Bacterial type IV secretion systems in human disease. Molecular microbiology, Vol. 73, H. 2. pp. 141-151.

Pulliainen, A. T. and Dehio, C.. (2009) Bartonella henselae : subversion of vascular endothelial cell functions by translocated bacterial effector proteins. The international journal of biochemistry & cell biology, Vol. 41, H. 3. pp. 507-510.

Rhomberg, T. A. and Truttmann, M. C. and Guye, P. and Ellner, Y. and Dehio, C.. (2009) A translocated protein of Bartonella henselae interferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the invasome. Cellular Microbiology, Vol. 11, H. 6. pp. 927-945.

Scheidegger, F. and Ellner, Y. and Guye, P. and Rhomberg, T. A. and Weber, H. and Augustin, H. G. and Dehio, C.. (2009) Distinct activities of Bartonella henselae type IV secretion effector proteins modulate capillary-like sprout formation. Cellular Microbiology, Vol. 11, H. 7. pp. 1088-1101.

Scheidegger, Florine. The role of the VirB/VirD4/Bep system in "Bartonella henselae"-triggered vascular proliferation. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Selbach, M. and Paul, F. E. and Brandt, S. and Guye, P. and Daumke, O. and Backert, S. and Dehio, C. and Mann, M.. (2009) Host cell interactome of tyrosine-phosphorylated bacterial proteins. Cell Host & Microbe, Vol. 5, H. 4. pp. 397-403.

2008

Dehio, C.. (2008) Infection-associated type IV secretion systems of Bartonella and their diverse roles in host cell interaction. Cellular Microbiology, Vol. 10, H. 8. pp. 1591-1598.

Wang, Xueya. Antigen - presentation by vascular endothelium : its role for CTL - mediated vascular injury. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

2007

Rhomberg, Thomas Alexander. Molecular and cellular basis of the internalization of "Bartonella henselae" by human endothelial cells. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Saenz, H. L. and Engel, P. and Stoeckli, M. C. and Lanz, C. and Raddatz, G. and Vayssier-Taussat, M. and Birtles, R. and Schuster, S. C. and Dehio, C.. (2007) Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nature Genetics, Vol. 39, H. 12. pp. 1469-1476.

San Paolo, Salvatore. Characterization of regulatory pathways controlling morphological differentiation in "Streptomyces coelicolor". 2007, Doctoral Thesis, University of Basel, Faculty of Science.

2006

Guye-Vuillème, Patrick. Proteins injected by the bacterial pathogen "Bartonella" subvert eukaryotic cell signaling. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Schmid, M. C. and Scheidegger, F. and Dehio, M. and Balmelle-Devaux, N. and Schulein, R. and Guye, P. and Chennakesava, C. S. and Biedermann, B. and Dehio, C.. (2006) A translocated bacterial protein protects vascular endothelial cells from apoptosis. PLoS Pathogens, 2 (11). e115.

2005

Dehio, C.. (2005) Bartonella-host-cell interactions and vascular tumour formation. Nature Reviews Microbiology, Vol. 3, H. 8. pp. 621-631.

Fiedler, J. and Leucht, F. and Waltenberger, J. and Dehio, C. and Brenner, R. E.. (2005) VEGF-A and PlGF-1 stimulate chemotactic migration of human mesenchymal progenitor cells. Biochemical and Biophysical Research Communications, Vol. 334, H. 2. pp. 561-568.

Lindroos, H. L. and Mira, A. and Repsilber, D. and Vinnere, O. and Naslund, K. and Dehio, M. and Dehio, C. and Andersson, S. G. E.. (2005) Characterization of the genome composition of Bartonella koehlerae by microarray comparative genomic hybridization profiling. Journal of bacteriology, Vol. 187, H. 17. pp. 6155-6165.

Mavris, M. and Saenz, H. and Monteil, M. and Boulouis, H. -J. and Dehio, C. and Vayssier-Taussat, M.. (2005) Characterization of genes involved in long-term bacteremia in mice by Bartonella birtlesii. Annals of the New York Academy of Sciences, Vol. 1063. pp. 312-314.

Saenz, H. L. and Dehio, C.. (2005) Signature-tagged mutagenesis : technical advances in a negative selection method for virulence gene identification. Current Opinion in Microbiology, Vol. 8, H. 5. pp. 612-619.

Saenz Dürrmeier, Luis-Henri. Large-scale identification of pathogenicity factors in "Bartonella" by signature-tagged mutagenesis. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Schmid, Michael Christoph. Subversion of endothelial cell functions by the human pathogen "Bartonella henselae". 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Schroder, G. and Dehio, C.. (2005) Virulence-associated type IV secretion systems of Bartonella. Trends in microbiology, Vol. 13, H. 7. pp. 336-342.

Schulein, R. and Guye, P. and Rhomberg, T. A. and Schmid, M. C. and Schroder, G. and Vergunst, A. C. and Carena, I. and Dehio, C.. (2005) A bipartite signal mediates the transfer of type IV secretion substrates of Bartonella henselae into human cells. Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, H. 3. pp. 856-861.

de Paz, H. D. and Sangari, F. J. and Bolland, S. and Garcia-Lobo, J. M. and Dehio, C. and de la Cruz, F. and Llosa, M.. (2005) Functional interactions between type IV secretion systems involved in DNA transfer and virulence. Microbiology, Vol. 151, H. Pt 11. pp. 3505-3516.

2004

Dehio, C.. (2004) Molecular and cellular basis of bartonella pathogenesis. Annual review of microbiology, Vol. 58. pp. 365-390.

Dehio, C. and Sauder, U. and Hiestand, R.. (2004) Isolation of Bartonella schoenbuchensis from Lipoptena cervi, a blood-sucking arthropod causing deer ked dermatitis. Journal of clinical microbiology, Vol. 42, H. 11. pp. 5320-5323.

Niehus, E. and Gressmann, H. and Ye, F. and Schlapbach, R. and Dehio, M. and Dehio, C. and Stack, A. and Meyer, T. F. and Suerbaum, S. and Josenhans, C.. (2004) Genome-wide analysis of transcriptional hierarchy and feedback regulation in the flagellar system of Helicobacter pylori. Molecular microbiology, Vol. 52, H. 4. pp. 947-961.

Rhomberg, T. A. and Karlberg, O. and Mini, T. and Zimny-Arndt, U. and Wickenberg, U. and Rottgen, M. and Jungblut, P. R. and Jeno, P. and Andersson, S. G. E. and Dehio, C.. (2004) Proteomic analysis of the sarcosine-insoluble outer membrane fraction of the bacterial pathogen Bartonella henselae. Proteomics, Vol. 4, H. 10. pp. 3021-3033.

Schmid, M. C. and Schulein, R. and Dehio, M. and Denecker, G. and Carena, I. and Dehio, C.. (2004) The VirB type IV secretion system of Bartonella henselae mediates invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. Molecular microbiology, Vol. 52, H. 1. pp. 81-92.

Zahringer, U. and Lindner, B. and Knirel, Y. A. and van den Akker, W. M. R. and Hiestand, R. and Heine, H. and Dehio, C.. (2004) Structure and biological activity of the short-chain lipopolysaccharide from Bartonella henselae ATCC 49882T. Journal of Biological Chemistry, 279 (20). pp. 21046-21054.

2003

Autiero, M. and Waltenberger, J. and Communi, D. and Kranz, A. and Moons, L. and Lambrechts, D. and Kroll, J. and Plaisance, S. and De Mol, M. and Bono, F. and Kliche, S. and Fellbrich, G. and Ballmer-Hofer, K. and Maglione, D. and Mayr-Beyrle, U. and Dewerchin, M. and Dombrowski, S. and Stanimirovic, D. and Van Hummelen, P. and Dehio, C. and Hicklin, D. J. and Persico, G. and Herbert, J. -M. and Shibuya, M. and Collen, D. and Conway, E. M. and Carmeliet, P.. (2003) Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nature medicine, Vol. 9, H. 7. pp. 936-943.

Dehio, C.. (2003) Recent progress in understanding Bartonella-induced vascular proliferation. Current Opinion in Microbiology, Vol. 6, H. 1. pp. 61-65.

Heil, M. and Mitnacht-Krauss, R. and Issbrucker, K. and van den Heuvel, J. and Dehio, C. and Schaper, W. and Clauss, M. and Weich, H. A.. (2003) An engineered heparin-binding form of VEGF-E (hbVEGF-E) : biological effects in vitro and mobilizatiion of precursor cells. Angiogenesis, Vol. 6, H. 3. pp. 201-211.

Rziha, H. -J. and Bauer, B. and Adam, K. -H. and Rottgen, M. and Cottone, R. and Henkel, M. and Dehio, C. and Buttner, M.. (2003) Relatedness and heterogeneity at the near-terminal end of the genome of a parapoxvirus bovis 1 strain (B177) compared with parapoxvirus ovis (Orf virus). Journal of general virology, Vol. 84, no. 5. pp. 1111-1116.

Seubert, A. and Falch, C. and Birtles, R. J. and Schulein, R. and Dehio, C.. (2003) Characterization of the cryptic plasmid pBGR1 from Bartonella grahamii and construction of a versatile Escherichia coli-Bartonella spp. shuttle cloning vector. Plasmid, Vol. 49, H. 1. pp. 44-52.

Seubert, A. and Hiestand, R. and de la Cruz, F. and Dehio, C.. (2003) A bacterial conjugation machinery recruited for pathogenesis. Molecular microbiology, Vol. 49, H. 5. pp. 1253-1266.

2002

Bermond, D. and Boulouis, H. -J. and Heller, R. and Van Laere, G. and Monteil, H. and Chomel, B. B. and Sander, A. and Dehio, C. and Piemont, Y.. (2002) Bartonella bovis Bermond et al. sp. nov. and Bartonella capreoli sp. nov., isolated from European ruminants. International journal of systematic and evolutionary microbiology, Vol. 52, H. Pt 2. pp. 383-390.

Mayr-Wohlfart, U. and Waltenberger, J. and Hausser, H. and Kessler, S. and Gunther, K. -P. and Dehio, C. and Puhl, W. and Brenner, R. E.. (2002) Vascular endothelial growth factor stimulates chemotactic migration of primary human osteoblasts. Bone, Vol. 30, H. 3. pp. 472-477.

Schulein, R. and Dehio, C.. (2002) The VirB/VirD4 type IV secretion system of Bartonella is essential for establishing intraerythrocytic infection. Molecular microbiology, Vol. 46, H. 4. pp. 1053-1067.

Seubert, A. and Schulein, R. and Dehio, C.. (2002) Bacterial persistence within erythrocytes : a unique pathogenic strategy of Bartonella spp. International Journal of Medical Microbiology : IJMM, Vol. 291, H. 6/7. pp. 555-560.

Upalakalin, J. N. and Hemo, I. and Dehio, C. and Keshet, E. and Benjamin, L. E.. (2002) Survival mechanisms of VEGF and PlGF during microvascular remodeling. Cold Spring Harbor Symposia on Quantitative Biology, 67. pp. 181-187.

2001

Dehio, C.. (2001) Bartonella interactions with endothelial cells and erythrocytes. Trends in Microbiology, Vol. 9, H. 6. pp. 279-285.

Dehio, C. and Lanz, C. and Pohl, R. and Behrens, P. and Bermond, D. and Piemont, Y. and Pelz, K. and Sander, A.. (2001) Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer. International journal of systematic and evolutionary microbiology, Vol. 51, H. Pt 4. pp. 1557-1565.

Fuhrmann, O. and Arvand, M. and Gohler, A. and Schmid, M. and Krull, M. and Hippenstiel, S. and Seybold, J. and Dehio, C. and Suttorp, N.. (2001) Bartonella henselae induces NF-kappaB-dependent upregulation of adhesion molecules in cultured human endothelial cells : possible role of outer membrane proteins as pathogenic factors. Infection and immunity, Vol. 69, H. 8. pp. 5088-5097.

Koesling, J. and Aebischer, T. and Falch, C. and Schulein, R. and Dehio, C.. (2001) Cutting edge : antibody-mediated cessation of hemotropic infection by the intraerythrocytic mouse pathogen Bartonella grahamii. Journal of immunology, Vol. 167, H. 1. pp. 11-14.

Raddatz, G. and Dehio, M. and Meyer, T. F. and Dehio, C.. (2001) PrimeArray : genome-scale primer design for DNA-microarray construction. Bioinformatics, 17 (1). pp. 98-99.

Schulein, R. and Seubert, A. and Gille, C. and Lanz, C. and Hansmann, Y. and Piemont, Y. and Dehio, C.. (2001) Invasion and persistent intracellular colonization of erythrocytes : A unique parasitic strategy of the emerging pathogen Bartonella. Journal of experimental medicine, Vol. 193, No. 9. pp. 1077-1086.

2000

Andersson, S. G. and Dehio, C.. (2000) Rickettsia prowazekii and Bartonella henselae : differences in the intracellular life styles revisited. International journal of medical microbiology, Vol. 290, H. 2. pp. 135-141.

Bermond, D. and Heller, R. and Barrat, F. and Delacour, G. and Dehio, C. and Alliot, A. and Monteil, H. and Chomel, B. and Boulouis, H. J. and Piemont, Y.. (2000) Bartonella birtlesii sp. nov., isolated from small mammals (Apodemus spp.). International journal of systematic and evolutionary microbiology, Vol. 50 , no. 1. pp. 1973-1979.

Dehio, C. and Gray-Owen, S. D. and Meyer, T. F.. (2000) Host cell invasion by pathogenic Neisseriae. Subcellular biochemistry, Vol. 33. pp. 61-96.

Freissler, E. and Meyer auf der Heyde, A. and David, G. and Meyer, T. F. and Dehio, C.. (2000) Syndecan-1 and syndecan-4 can mediate the invasion of OpaHSPG-expressing Neisseria gonorrhoeae into epithelial cells. Cellular microbiology, Vol. 2, H. 1. pp. 69-82.

Gray-Owen, S. D. and Dehio, C. and Naumann, M. and Rudel, T. and Meyer, T. F.. (2000) Neisseria. In: Principles of bacterial pathogenesis. San Diego, Calif. ; London.

Muenzner, P. and Dehio, C. and Fujiwara, T. and Achtman, M. and Meyer, T. F. and Gray-Owen, S. D.. (2000) Carcinoembryonic antigen family receptor specificity of Neisseria meningitidis Opa variants influences adherence to and invasion of proinflammatory cytokine-activated endothelial cells. Infection and immunity, Vol. 68, H. 6. pp. 3601-3607.

Rziha, H. and Henkel, M. and Cottone, R. and Bauer, B. and Auge, U. and Gotz, F. and Pfaff, E. and Rottgen, M. and Dehio, C. and Buttner, M.. (2000) Generation of recombinant parapoxviruses: non-essential genes suitable for insertion and expression of foreign genes. Journal of biotechnology, Vol. 83, H. 1/2. pp. 137-145.

Sander, A. and Zagrosek, A. and Bredt, W. and Schiltz, E. and Piemont, Y. and Lanz, C. and Dehio, C.. (2000) Characterization of Bartonella clarridgeiae flagellin (FlaA) and detection of antiflagellin antibodies in patients with lymphadenopathy. Journal of clinical microbiology, Vol. 38, H. 8. pp. 2943-2948.

1999

Dehio, C. and Sander, A.. (1999) Bartonella as emerging pathogens. Trends in microbiology, Vol. 7, H. 6. pp. 226-228.

Heller, R. and Kubina, M. and Mariet, P. and Riegel, P. and Delacour, G. and Dehio, C. and Lamarque, F. and Kasten, R. and Boulouis, H. J. and Monteil, H. and Chomel, B. and Piemont, Y.. (1999) Bartonella alsatica sp. nov. : a new Bartonella species isolated from the blood of wild rabbits. International Journal of Systematic Bacteriology, 49 (1). pp. 283-288.

Meyer, M. and Clauss, M. and Lepple-Wienhues, A. and Waltenberger, J. and Augustin, H. G. and Ziche, M. and Lanz, C. and Buttner, M. and Rziha, H. J. and Dehio, C.. (1999) A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases. The EMBO journal, Vol. 18, H. 2. pp. 363-374.

Popp, A. and Dehio, C. and Grunert, F. and Meyer, T. F. and Gray-Owen, S. D.. (1999) Molecular analysis of neisserial Opa protein interactions with the CEA family of receptors : identification of determinants contributing to the differential specificities of binding. Cellular Microbiology, Vol. 1, H. 2. pp. 169-181.

Rziha, H. J. and Henkel, M. and Cottone, R. and Meyer, M. and Dehio, C. and Buttner, M.. (1999) Parapoxviruses : potential alternative vectors for directing the immune response in permissive and non-permissive hosts. Journal of biotechnology, Vol. 73, H. 2/3. pp. 235-242.

1998

Dehio, C. and Freissler, E. and Lanz, C. and Gomez-Duarte, O. G. and David, G. and Meyer, T. F.. (1998) Ligation of cell surface heparan sulfate proteoglycans by antibody-coated beads stimulates phagocytic uptake into epithelial cells : a model for cellular invasion by Neisseria gonorrhoeae. Experimental cell research, Vol. 242, H. 2. pp. 528-539.

Dehio, C. and Gray-Owen, S. D. and Meyer, T. F.. (1998) The role of neisserial Opa proteins in interactions with host cells. Trends in microbiology, Vol. 6, H. 12. pp. 489-495.

Dehio, M. and Gomez-Duarte, O. G. and Dehio, C. and Meyer, T. F.. (1998) Vitronectin-dependent invasion of epithelial cells by Neisseria gonorrhoeae involves alpha(v) integrin receptors. FEBS letters, Vol. 424, H. 1/2. pp. 84-88.

Dehio, M. and Knorre, A. and Lanz, C. and Dehio, C.. (1998) Construction of versatile high-level expression vectors for Bartonella henselae and the use of green fluorescent protein as a new expression marker. Gene, Vol. 215, H. 2. pp. 223-229.

Heller, R. and Riegel, P. and Hansmann, Y. and Delacour, G. and Bermond, D. and Dehio, C. and Lamarque, F. and Monteil, H. and Chomel, B. and Piemont, Y.. (1998) Bartonella tribocorum sp. nov. : a new Bartonella species isolated from the blood of wild rats. International Journal of Systematic Bacteriology, 48 (4). pp. 1333-1339.

Wang, J. and Gray-Owen, S. D. and Knorre, A. and Meyer, T. F. and Dehio, C.. (1998) Opa binding to cellular CD66 receptors mediates the transcellular traversal of Neisseria gonorrhoeae across polarized T84 epithelial cell monolayers. Molecular microbiology, Vol. 30, H. 3. pp. 657-671.

1997

Dehio, C.. (1997) Pathogenicity of Bartonella spp. Bulletin de l'Institut Pasteur, Vol. 95. pp. 197-207.

Dehio, C. and Meyer, M.. (1997) Maintenance of broad-host-range incompatibility group P and group Q plasmids and transposition of Tn5 in Bartonella henselae following conjugal plasmid transfer from Escherichia coli. Journal of bacteriology, Vol. 179, H. 2. pp. 538-540.

Dehio, C. and Meyer, M. and Berger, J. and Schwarz, H. and Lanz, C.. (1997) Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasome. Journal of Cell Science, 110 (18). pp. 2141-2154.

Gomez-Duarte, O. G. and Dehio, M. and Guzman, C. A. and Chhatwal, G. S. and Dehio, C. and Meyer, T. F.. (1997) Binding of vitronectin to opa-expressing Neisseria gonorrhoeae mediates invasion of HeLa cells. Infection and immunity, Vol. 65, H. 9. pp. 3857-3866.

Gray-Owen, S. D. and Dehio, C. and Haude, A. and Grunert, F. and Meyer, T. F.. (1997) CD66 carcinoembryonic antigens mediate interactions between Opa-expressing Neisseria gonorrhoeae and human polymorphonuclear phagocytes. The EMBO journal, Vol. 16, H. 12. pp. 3435-3445.

Gray-Owen, S. D. and Lorenzen, D. R. and Haude, A. and Meyer, T. F. and Dehio, C.. (1997) Differential Opa specificities for CD66 receptors influence tissue interactions and cellular response to Neisseria gonorrhoeae. Molecular microbiology, Vol. 26, H. 5. pp. 971-980.

1996

Menard, R. and Dehio, C. and Sansonetti, P. J.. (1996) Bacterial entry into epithelial cells : the paradigm of Shigella. Trends in microbiology, Vol. 4, H. 6. pp. 220-226.

Menard, R. and Prevost, M. C. and Gounon, P. and Sansonetti, P. and Dehio, C.. (1996) The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, H. 3. pp. 1254-1258.

1995

Dehio, C. and Prevost, M. C. and Sansonetti, P. J.. (1995) Invasion of epithelial cells by Shigella flexneri induces tyrosine phosphorylation of cortactin by a pp60c-src-mediated signalling pathway. The EMBO journal, Vol. 14, H. 11. pp. 2471-2482.

1994

Dehio, C. and Schell, J.. (1994) Identification of plant genetic loci involved in a posttranscriptional mechanism for meiotically reversible transgene silencing. Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, H. 12. pp. 5538-5542.

Magrelli, A. and Langenkemper, K. and Dehio, C. and Schell, J. and Spena, A.. (1994) Splicing of the rolA transcript of Agrobacterium rhizogenes in Arabidopsis. Science, Vol. 266, no. 5193. pp. 1986-1988.

1993

Dehio, C. and Grossmann, K. and Schell, J. and Schmulling, T.. (1993) Phenotype and hormonal status of transgenic tobacco plants overexpressing the rolA gene of Agrobacterium rhizogenes T-DNA. Plant Molecular Biology, Vol. 23, H. 6. pp. 1199-1210.

Dehio, C. and Schell, J.. (1993) Stable expression of a single-copy rolA gene in transgenic Arabidopsis thaliana plants allows an exhaustive mutagenic analysis of the transgene-associated phenotype. Molecular and general genetics, Vol. 241, no. 3-4. pp. 359-366.

1992

Dehio, C. and de Bruijn, F. J.. (1992) The early nodulin gene SrEnod2 from Sesbania rostrata is inducible by cytokinin. >>The<< Plant Journal, Vol. 2, H. 1. pp. 117-128.