Items where Division is "05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Growth and Development (Moroni)
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Lattmann, Simon. Investigation of the guanine quadruplex resolving activity of the DEAH-box RNA helicase RHAU. 2012, Doctoral Thesis, University of Basel, Faculty of Science.
Benjamin, Don and Colombi, Marco and Moroni, Christoph and Hall, Michael N.. (2011) Rapamycin passes the torch: a new generation of mTOR inhibitors. Nature Reviews. Drug Discovery, 10 (11). pp. 868-880.
Colombi, M. and Molle, K. D. and Benjamin, D. and Rattenbacher-Kiser, K. and Schaefer, C. and Betz, C. and Thiemeyer, A. and Regenass, U. and Hall, M. N. and Moroni, C.. (2011) Genome-wide shRNA screen reveals increased mitochondrial dependence upon mTORC2 addiction. Oncogene, 30 (13). pp. 1551-1565.
Louvel, Séverine. Validation of replicative phenotyping to detect and assign HIV-1 resistance in clinical specimens. 2009, Doctoral Thesis, University of Basel, Faculty of Science.
Benjamin, D. and Moroni, C.. (2007) mRNA stability and cancer : an emerging link? Expert opinion on biological therapy, Vol. 7, H. 10. pp. 1515-1529.
Bloch, Michael. Amplification of KCNMA1 : a potential therapeutic target in prostate cancer. 2007, Doctoral Thesis, University of Basel, Faculty of Science.
Essafi-Benkhadir, K. and Onesto, C. and Stebe, E. and Moroni, C. and Pages, G.. (2007) Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation. Molecular Biology of the Cell, 18 (11). pp. 4648-4658.
Wegmuller, D. and Raineri, I. and Gross, B. and Oakeley, E. J. and Moroni, C.. (2007) A cassette system to study embryonic stem cell differentiation by inducible RNA interference. Stem Cells, Vol. 25, H. 5. pp. 1178-1185.
Benjamin, D. and Colombi, M. and Stoecklin, G. and Moroni, C.. (2006) A GFP-based assay for monitoring post-transcriptional regulation of ARE-mRNA turnover. Molecular BioSystems, Vol. 2, H. 11. pp. 561-567.
Benjamin, D. and Schmidlin, M. and Min, L. and Gross, B. and Moroni, C.. (2006) BRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sites. Molecular and Cellular Biology, Vol. 26, H. 24. pp. 9497-9507.
Gherzi, R. and Trabucchi, M. and Ponassi, M. and Ruggiero, T. and Corte, G. and Moroni, C. and Chen, C. -Y. and Khabar, K. S. and Andersen, J. S. and Briata, P.. (2006) The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling. PLoS Biology, Vol. 5, H. 1 , e5.
Kiser, K. F. and Colombi, M. and Moroni, C.. (2006) Isolation and characterization of dominant and recessive IL-3-independent hematopoietic transformants. Oncogene, Vol. 25, H. 50. pp. 6595-6603.
Smulevitch, S. and Bear, J. and Alicea, C. and Rosati, M. and Jalah, R. and Zolotukhin, A. S. and von Gegerfelt, A. and Michalowski, D. and Moroni, C. and Pavlakis, G. N. and Felber, B. K.. (2006) RTE and CTE mRNA export elements synergistically increase expression of unstable, Rev-dependent HIV and SIV mRNAs. Retrovirology, Vol. 3 , 6.
Benjamin, D. and Colombi, M. and Moroni, C.. (2004) A GFP-based assay for rapid screening of compounds affecting ARE-dependent mRNA turnover. Nucleic Acids Research, 32 (11). e89.
Gherzi, R. and Lee, K. -Y. and Briata, P. and Wegmuller, D. and Moroni, C. and Karin, M. and Chen, C. -Y.. (2004) A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Molecular cell, Vol. 14, H. 5. pp. 571-583.
Leuenberger, Sabrina Angélique. On the role of ras and BRF1 in the regulation of ARE-dependent mRNA-turnover. 2004, Doctoral Thesis, University of Basel, Faculty of Science.
Raineri, I. and Wegmueller, D. and Gross, B. and Certa, U. and Moroni, C.. (2004) Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference. Nucleic Acids Research, 32 (4). pp. 1279-1288.
Schmidlin, M. and Lu, M. and Leuenberger, S. A. and Stoecklin, G. and Mallaun, M. and Gross, B. and Gherzi, R. and Hess, D. and Hemmings, B. A. and Moroni, C.. (2004) The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B. The EMBO journal, Vol. 23, H. 24. pp. 4760-4769.
Briata, P. and Ilengo, C. and Corte, G. and Moroni, C. and Rosenfeld, M. G. and Chen, C. -Y. and Gherzi, R.. (2003) The Wnt/beta-catenin--<Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs. Molecular cell, Vol. 12, H. 5. pp. 1201-1211.
Stoecklin, G. and Gross, B. and Ming, X. -F. and Moroni, C.. (2003) A novel mechanism of tumor suppression by destabilizing AU-rich growth factor mRNA. Oncogene, Vol. 22, H. 23. pp. 3554-3561.
Stoecklin, G. and Lu, M. and Rattenbacher, B. and Moroni, C.. (2003) A constitutive decay element promotes tumor necrosis factor alpha mRNA degradation via an AU-rich element-independent pathway. Molecular and cellular biology, Vol. 23, H. 10. pp. 3506-3515.
Struckmann, Kirsten. Differential gene expression screening uncovers downregulation of the cell cycle regulator BTG2 as an important step in renal tumor biology. 2003, Doctoral Thesis, University of Basel, Faculty of Science.
Stoecklin, G. and Colombi, M. and Raineri, I. and Leuenberger, S. and Mallaun, M. and Schmidlin, M. and Gross, B. and Lu, M. and Kitamura, T. and Moroni, C.. (2002) Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover. The EMBO journal, Vol. 21, H. 17. pp. 4709-4718.
Brem, R. and Certa, U. and Neeb, M. and Nair, A. P. and Moroni, C.. (2001) Global analysis of differential gene expression after transformation with the v-H-ras oncogene in a murine tumor model. Oncogene, Vol. 20, H. 22. pp. 2854-2858.
Ming, X. F. and Stoecklin, G. and Lu, M. and Looser, R. and Moroni, C.. (2001) Parallel and independent regulation of interleukin-3 mRNA turnover by phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase. Molecular and cellular biology, Vol. 21, H. 17. pp. 5778-5789.
Stoecklin, G. and Stoeckle, P. and Lu, M. and Muehlemann, O. and Moroni, C.. (2001) Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements. RNA, Vol. 7, H. 11. pp. 1578-1588.
Stoecklin, G. and Ming, X. F. and Looser, R. and Moroni, C.. (2000) Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin-3 mRNA degradation pathway. Molecular and Cellular Biology, Vol. 20, H. 11. pp. 3753-3763.
Wyss, A. and Moroni, C.. (2000) Calcium-dependent and oncogenic IL-3 mRNA stabilization can be distinguished pharmacologically and by sequence requirements in the 3'UTR. Growth Factors, Vol. 18, H. 2. pp. 109-118.
Brennan, L. E. and Nakagawa, J. and Egger, D. and Bienz, K. and Moroni, C.. (1999) Characterisation and mitochondrial localisation of AUH : an AU-specific RNA-binding enoyl-CoA hydratase. Gene, Vol. 228, H. 1/2. pp. 85-91.
Buess, M. and Engler, O. and Hirsch, H. H. and Moroni, C.. (1999) Search for oncogenic regulators in an autocrine tumor model using differential display PCR : identification of novel candidate genes including the calcium channel mtrp6. Oncogene, Vol. 18, H. 7. pp. 1487-1494.
Nair, A. P. and Hirsch, H. H. and Colombi, M. and Moroni, C.. (1999) Cyclosporin A promotes translational silencing of autocrine interleukin-3 via ribosome-associated deadenylation. Molecular and Cellular Biology, Vol. 19, H. 1. pp. 889-898.
Ming, X. F. and Kaiser, M. and Moroni, C.. (1998) c-jun N-terminal kinase is involved in AUUUA-mediated interleukin-3 mRNA turnover in mast cells. The EMBO journal, Vol. 17, H. 20. pp. 6039-6048.
Aebersold, D. M. and Banholzer, R. and Backenstoss, V. and Hirsch, H. H. and Moroni, C.. (1997) V-Ha-ras-dependent expression of interleukin-3 mRNA in premalignant PB-3c mast cells correlates with the formation of tumors without interleukin-3 gene rearrangements. Experimental hematology, Vol. 25, H. 5. pp. 395-404.
Buess, M. and Moroni, C. and Hirsch, H. H.. (1997) Direct identification of differentially expressed genes by cycle sequencing and cycle labelling using the differential display PCR primers. Nucleic Acids Research, 25 (11). pp. 2233-2235.
Gratzl, S. and Moroni, C. and Hirsch, H. H.. (1997) Quantification of HIV-1 viral RNA and proviral DNA by isotopic competitive PCR. Journal of Virological Methods, Vol. 66, H. 2. pp. 269-282.
Nakagawa, J. and Moroni, C.. (1997) A 20-amino-acid autonomous RNA-binding domain contained in an enoyl-CoA hydratase. European journal of biochemistry, Vol. 244, H. 3. pp. 890-899.
Rothen, M. and Gratzl, S. and Hirsch, H. H. and Moroni, C.. (1997) Apoptosis in HIV-infected individuals is an early marker occurring independently of high viremia. AIDS Research and Human Retroviruses, Vol. 13, H. 9. pp. 771-779.
Vatteroni, M. and Maggi, F. and Morrica, A. and Fornai, C. and Giorgi, M. and Pistello, M. and Bendinelli, M.. (1997) Comparative evaluation of five rapid methods for identifying subtype 1b and 2c hepatitis C virus isolates. Journal of Virological Methods, Vol. 66, H. 2. pp. 187-194.
Hirsch, H. H. and Backenstoss, V. and Moroni, C.. (1996) Impaired interleukin-3 mRNA decay in autocrine mast cell tumors after transient calcium ionophore stimulation. Growth Factors, Vol. 13, H. 1/2. pp. 99-110.
Hirsch, H. H. and Nair, A. P. and Backenstoss, V. and Moroni, C.. (1995) Interleukin-3 mRNA stabilization by a trans-acting mechanism in autocrine tumors lacking interleukin-3 gene rearrangements. Journal of biological chemistry, Vol. 270 , no. 35. pp. 20629-20635.
Nakagawa, J. and Waldner, H. and Meyer-Monard, S. and Hofsteenge, J. and Jeno, P. and Moroni, C.. (1995) AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity. Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, H. 6. pp. 2051-2055.
Hahn, S. and Moroni, C.. (1994) Modulation of cytokine expression in PB-3c mastocytes by IBMX and PMA. Lymphokine and cytokine research, Vol. 13, H. 4. pp. 247-252.
Nair, A. P. and Hahn, S. and Banholzer, R. and Hirsch, H. H. and Moroni, C.. (1994) Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA. Nature, Vol. 369. pp. 239-242.
Pietrzak, J. and Frei, R. and Senn, H. P. and Moroni, C.. (1994) Comparison of polymerase chain reaction with standard methods in the diagnosis of Mycobacterium tuberculosis infection. European journal of clinical microbiology & infectious diseases, Vol. 13, H. 12. pp. 1079-1083.
Stoecklin, G. and Hahn, S. and Moroni, C.. (1994) Functional hierarchy of AUUUA motifs in mediating rapid interleukin-3 mRNA decay. Journal of biological chemistry, Vol. 269 , no. 46. pp. 28591-28597.
Hirsch, H. H. and Nair, A. P. and Moroni, C.. (1993) Suppressible and nonsuppressible autocrine mast cell tumors are distinguished by insertion of an endogenous retroviral element (IAP) into the interleukin 3 gene. The Journal of Experimental Medicine, Vol. 178, H. 2. pp. 403-411.
Hahn, S. and Wodnar-Filipowicz, A. and Nair, A. P. and Moroni, C.. (1991) Ras oncogenes amplify lymphokine (interleukin 3, granulocyte-macrophage colony-stimulating factor) induction by calcium ionophore. Oncogene, Vol. 6, H. 12. pp. 2327-2332.
Raineri, I. and Moroni, C. and Senn, H. P.. (1991) Improved efficiency for single-sided PCR by creating a reusable pool of first-strand cDNA coupled to a solid phase. Nucleic Acids Research, 19 (14). p. 4010.
Wodnar-Filipowicz, A. and Moroni, C.. (1990) Regulation of interleukin 3 mRNA expression in mast cells occurs at the posttranscriptional level and is mediated by calcium ions. Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, H. 2. pp. 777-781.
Andrejauskas, E. and Moroni, C.. (1989) Reversible abrogation of IL-3 dependence by an inducible H-ras oncogene. The EMBO journal, Vol. 8, H. 9. pp. 2575-2581.
Diamantis, I. D. and Nair, A. P. and Hirsch, H. H. and Moroni, C.. (1989) Tumor suppression involves down-regulation of interleukin 3 expression in hybrids between autocrine mastocytoma and interleukin 3-dependent parental mast cells. Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, H. 23. pp. 9299-9302.
Moroni, C. and Diamantis, I. D. and Wodnar-Filipowicz, A. and Nair, A. P.. (1989) Multistage mastocytoma model characterized by autocrine IL-3 production. Modern trends in human leukemia, 8. pp. 407-410.
Muser, J. and Kaech, S. and Moroni, C. and Ballmer-Hofer, K.. (1989) Stimulation of pp60c-src kinase activity in FDC-P1 cells by polyoma middle-T antigen and hematopoietic growth factors. Oncogene, Vol. 4, H. 12. pp. 1433-1439.
Nair, A. P. and Diamantis, I. D. and Conscience, J. F. and Kindler, V. and Hofer, P. and Moroni, C.. (1989) A v-H-ras-dependent hemopoietic tumor model involving progression from a clonal stage of transformation competence to autocrine interleukin 3 production. Molecular and cellular biology, Vol. 9, H. 3. pp. 1183-1190.
Wodnar-Filipowicz, A. and Heusser, C. H. and Moroni, C.. (1989) Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activation. Nature, Vol. 339. pp. 150-152.
Senn, H. P. and Jiricny, J. and Fopp, M. and Schmid, L. and Moroni, C.. (1988) Relapse cell population differs from acute onset clone as shown by absence of the initially activated N-ras oncogene in a patient with acute myelomonocytic leukemia. Blood, Vol. 72, H. 3. pp. 931-935.
Senn, H. P. and Tran-Thang, C. and Wodnar-Filipowicz, A. and Jiricny, J. and Fopp, M. and Gratwohl, A. and Signer, E. and Weber, W. and Moroni, C.. (1988) Mutation analysis of the N-ras proto-oncogene in active and remission phase of human acute leukemias. International journal of cancer, Vol. 41, H. 1. pp. 59-64.
Nair, A. P. and Moroni, C.. (1987) v-H-ras gene reduces IL-3 requirement in PB-3c mastocytes in vitro followed by autokrine tumor formation in vivo. Modern trends in human leukemia, 7. pp. 257-260.
Wodnar-Filipowicz, A. and Senn, H. P. and Jiricny, J. and Signer, E. and Moroni, C.. (1987) Amino acid substitution at position 13 of the N-ras gene in a non-Hodgkin's lymphoma patient. Modern trends in human leukemia, 7. pp. 172-174.
Wodnar-Filipowicz, A. and Senn, H. P. and Jiricny, J. and Signer, E. and Moroni, C.. (1987) Glycine-cysteine substitution at codon 13 of the N-ras proto-oncogene in a human T cell non-Hodgkin's lymphoma. Oncogene, Vol. 1, H. 4. pp. 457-461.